HU9500966D0 - Method for the stereoselective preparation of a derivative of beta-phenylisoserine and its use in the preparation of taxane derivatives - Google Patents

Method for the stereoselective preparation of a derivative of beta-phenylisoserine and its use in the preparation of taxane derivatives

Info

Publication number
HU9500966D0
HU9500966D0 HU9500966A HU9500966A HU9500966D0 HU 9500966 D0 HU9500966 D0 HU 9500966D0 HU 9500966 A HU9500966 A HU 9500966A HU 9500966 A HU9500966 A HU 9500966A HU 9500966 D0 HU9500966 D0 HU 9500966D0
Authority
HU
Hungary
Prior art keywords
formula
pct
preparation
iii
phenylisoserine
Prior art date
Application number
HU9500966A
Other languages
English (en)
Other versions
HUT73171A (en
Inventor
Jean-Noel Denis
Andrew Greene
Alice Kanazawa
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of HU9500966D0 publication Critical patent/HU9500966D0/hu
Publication of HUT73171A publication Critical patent/HUT73171A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C27/00Processes involving the simultaneous production of more than one class of oxygen-containing compounds
    • C07C27/20Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction
    • C07C27/22Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction with the use of catalysts which are specific for this process
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU9500966A 1992-10-05 1993-10-04 Method for the stereoselective preparation of a derivative of beta-phenylisoserine and its use in the preparation of taxane derivatives HUT73171A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211740A FR2696454B1 (fr) 1992-10-05 1992-10-05 Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane.

Publications (2)

Publication Number Publication Date
HU9500966D0 true HU9500966D0 (en) 1995-06-28
HUT73171A HUT73171A (en) 1996-06-28

Family

ID=9434118

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9500966A HUT73171A (en) 1992-10-05 1993-10-04 Method for the stereoselective preparation of a derivative of beta-phenylisoserine and its use in the preparation of taxane derivatives

Country Status (23)

Country Link
US (2) US5726346A (hu)
EP (1) EP0663901B1 (hu)
JP (1) JPH08502051A (hu)
KR (1) KR100290664B1 (hu)
AT (1) ATE150451T1 (hu)
AU (1) AU682011B2 (hu)
CA (1) CA2146374A1 (hu)
CZ (1) CZ283290B6 (hu)
DE (1) DE69309086T2 (hu)
DK (1) DK0663901T3 (hu)
ES (1) ES2099479T3 (hu)
FI (1) FI951589A0 (hu)
FR (1) FR2696454B1 (hu)
GR (1) GR3022872T3 (hu)
HU (1) HUT73171A (hu)
MX (1) MX9305765A (hu)
NZ (1) NZ256444A (hu)
PL (2) PL176503B1 (hu)
RU (1) RU2109010C1 (hu)
SK (1) SK280576B6 (hu)
TW (1) TW436476B (hu)
WO (1) WO1994007847A1 (hu)
ZA (1) ZA937317B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7601847B2 (en) 2004-10-26 2009-10-13 Wyeth Preparation and purification of 4-(indazol-3-yl)phenols
WO2010024762A1 (en) * 2008-08-26 2010-03-04 Organoclick Aktiebolag PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES
WO2010062239A1 (en) * 2008-11-03 2010-06-03 Cordova Armando A catalytic asymmetric method for the preparation of the paclitaxel (taxol) c-13 side-chain derivatives and its use in the preparation of taxane derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
CA2023645C (fr) * 1989-08-23 2002-03-26 Jean-Noel Denis Procede pour la preparation enantioselective de derives de la phenylisoserine
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor

Also Published As

Publication number Publication date
PL308240A1 (en) 1995-07-24
EP0663901A1 (fr) 1995-07-26
WO1994007847A1 (fr) 1994-04-14
FR2696454B1 (fr) 1994-11-25
AU5114993A (en) 1994-04-26
HUT73171A (en) 1996-06-28
RU95111377A (ru) 1996-12-27
DE69309086T2 (de) 1997-09-25
KR950703499A (ko) 1995-09-20
EP0663901B1 (fr) 1997-03-19
TW436476B (en) 2001-05-28
CZ283290B6 (cs) 1998-02-18
GR3022872T3 (en) 1997-06-30
CA2146374A1 (fr) 1994-04-14
ATE150451T1 (de) 1997-04-15
NZ256444A (en) 1996-06-25
MX9305765A (es) 1994-05-31
SK43795A3 (en) 1995-09-13
FR2696454A1 (fr) 1994-04-08
RU2109010C1 (ru) 1998-04-20
FI951589A (fi) 1995-04-04
US5726346A (en) 1998-03-10
JPH08502051A (ja) 1996-03-05
FI951589A0 (fi) 1995-04-04
PL176503B1 (pl) 1999-06-30
US6114550A (en) 2000-09-05
ES2099479T3 (es) 1997-05-16
AU682011B2 (en) 1997-09-18
CZ84095A3 (en) 1995-09-13
PL173791B1 (pl) 1998-04-30
DK0663901T3 (da) 1997-04-14
ZA937317B (en) 1994-04-22
KR100290664B1 (ko) 2001-09-17
DE69309086D1 (de) 1997-04-24
SK280576B6 (sk) 2000-04-10

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