HU901048D0 - Process for preparation of substituted 2-amino-1,2,3,4-tetrahydronaphthalene and 3-chromane derivatives - Google Patents

Process for preparation of substituted 2-amino-1,2,3,4-tetrahydronaphthalene and 3-chromane derivatives

Info

Publication number
HU901048D0
HU901048D0 HU901048A HU104890A HU901048D0 HU 901048 D0 HU901048 D0 HU 901048D0 HU 901048 A HU901048 A HU 901048A HU 104890 A HU104890 A HU 104890A HU 901048 D0 HU901048 D0 HU 901048D0
Authority
HU
Hungary
Prior art keywords
alkyl
substituted
aryl
amino
tetrahydronaphthalene
Prior art date
Application number
HU901048A
Other languages
English (en)
Other versions
HUT53354A (en
HU209481B (en
Inventor
Michael Edward Flaugh
John Mehnert Schaus
Robert Daniel Titus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU901048D0 publication Critical patent/HU901048D0/hu
Publication of HUT53354A publication Critical patent/HUT53354A/hu
Publication of HU209481B publication Critical patent/HU209481B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/38—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU901048A 1989-02-27 1990-02-26 Process for the production of substituted 2-amino-1,2,3,4-tetrahydro-naphthalene and 3-aminochromane derivatives HU209481B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31575289A 1989-02-27 1989-02-27

Publications (3)

Publication Number Publication Date
HU901048D0 true HU901048D0 (en) 1990-05-28
HUT53354A HUT53354A (en) 1990-10-28
HU209481B HU209481B (en) 1994-06-28

Family

ID=23225899

Family Applications (2)

Application Number Title Priority Date Filing Date
HU901048A HU209481B (en) 1989-02-27 1990-02-26 Process for the production of substituted 2-amino-1,2,3,4-tetrahydro-naphthalene and 3-aminochromane derivatives
HU9202449A HU221625B1 (hu) 1989-02-27 1990-02-26 Eljárás optikailag aktív 2-amino-1,2,3,4-tetrahidro-naftalin-származékok előállítására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU9202449A HU221625B1 (hu) 1989-02-27 1990-02-26 Eljárás optikailag aktív 2-amino-1,2,3,4-tetrahidro-naftalin-származékok előállítására

Country Status (21)

Country Link
US (1) US5637624A (hu)
EP (1) EP0385658B1 (hu)
JP (2) JP2954255B2 (hu)
KR (1) KR900012890A (hu)
CN (2) CN1031262C (hu)
AT (1) ATE116289T1 (hu)
AU (1) AU630671B2 (hu)
CA (2) CA2362972A1 (hu)
DE (1) DE69015384T2 (hu)
DK (1) DK0385658T3 (hu)
ES (1) ES2065478T3 (hu)
GR (1) GR3015136T3 (hu)
HU (2) HU209481B (hu)
IE (1) IE65769B1 (hu)
IL (5) IL114715A (hu)
MX (1) MX19637A (hu)
NZ (1) NZ232628A (hu)
PH (1) PH27444A (hu)
PT (1) PT93218B (hu)
RU (1) RU1826966C (hu)
ZA (1) ZA901277B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
JPH04504721A (ja) * 1989-04-27 1992-08-20 ジ・アップジョン・カンパニー 置換３―アミノ・クロマン類
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
ES2041211B1 (es) * 1992-02-17 1994-05-16 Uriach & Cia Sa J Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos.
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
GB9514417D0 (en) * 1995-07-14 1995-09-13 Iaf Biochem Int Novel heterocyclic compounds for the treatment of pain and use thereof
WO1999001121A1 (en) 1997-07-01 1999-01-14 Pfizer Inc. Sertraline salts and sustained-release dosage forms of sertraline
FR2792529B1 (fr) * 1999-04-26 2001-09-28 Sod Conseils Rech Applic Nouvelles compositions pharmaceutiques comprenant des derives de 2-isoxazole-8-aminotetralines
WO2005037830A1 (en) * 2003-10-10 2005-04-28 Wyeth Piperidinylchromen-6-ylsulfonamide compounds as 5-hydroxytryptamine-6 ligands
WO2006066746A1 (en) * 2004-12-21 2006-06-29 F. Hoffmann-La Roche Ag Chroman derivatives and their use as 5-ht receptor ligands
WO2007051735A1 (en) * 2005-11-03 2007-05-10 F. Hoffmann-La Roche Ag Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
EP2098511A1 (en) 2008-03-07 2009-09-09 Solvias AG Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring
EP2338873A1 (en) 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
KR102020441B1 (ko) * 2017-05-30 2019-09-11 주식회사 포스코 충전강관기둥 및, 강관기둥구조체

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253037A (en) * 1962-06-19 1966-05-24 Ciba Geigy Corp N-2-alkynyl-amino-benzocylo-alkanes
GB1037014A (en) * 1963-08-02 1966-07-20 Aspro Nicholas Ltd Derivatives of 1-aminoindane
US3709996A (en) * 1963-08-02 1973-01-09 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-aminoindane compounds and adapted for administration to obtain inhibition of monoamine oxidase enzyme and process
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3758640A (en) * 1970-07-20 1973-09-11 Hooker Chemical Corp Opolymer and a polyester polymer composition comprising vinylmonomer butadiene polymer graft c
US3929891A (en) * 1971-02-08 1975-12-30 Hoechst Ag Reduction of halonitroaromates using sulfited platinum on carbon catalysts
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
WO1987002035A1 (en) * 1985-10-04 1987-04-09 Maggioni-Winthrop S.P.A. Fused cycloaliphatic aminoalcohols
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
ATE113271T1 (de) * 1989-01-09 1994-11-15 Upjohn Co Halogensubstituierte aminotetraline.
JP2885317B2 (ja) * 1989-01-31 1999-04-19 三菱化学株式会社 耐衝撃熱可塑性樹脂組成物の製造方法

Also Published As

Publication number Publication date
HU221625B1 (hu) 2002-12-28
CN1045099A (zh) 1990-09-05
AU5014490A (en) 1990-10-25
JPH11315063A (ja) 1999-11-16
IL93464A (en) 1996-10-16
GR3015136T3 (en) 1995-05-31
ES2065478T3 (es) 1995-02-16
MX19637A (es) 1994-02-28
US5637624A (en) 1997-06-10
DE69015384D1 (de) 1995-02-09
NZ232628A (en) 1992-03-26
DE69015384T2 (de) 1995-05-18
EP0385658A1 (en) 1990-09-05
KR900012890A (ko) 1990-09-03
JP3000016B2 (ja) 2000-01-17
IL109647A0 (en) 1994-08-26
PT93218B (pt) 1996-03-29
PH27444A (en) 1993-07-02
CN1031262C (zh) 1996-03-13
CA2010542A1 (en) 1990-08-27
AU630671B2 (en) 1992-11-05
IL114715A0 (en) 1995-11-27
IL109647A (en) 1997-04-15
ZA901277B (en) 1991-10-30
ATE116289T1 (de) 1995-01-15
CN1120532A (zh) 1996-04-17
JPH02268151A (ja) 1990-11-01
IE900684L (en) 1990-08-27
HUT53354A (en) 1990-10-28
IL93464A0 (en) 1990-11-29
PT93218A (pt) 1990-08-31
CN1051990C (zh) 2000-05-03
DK0385658T3 (da) 1995-02-20
HU9202449D0 (en) 1992-12-28
JP2954255B2 (ja) 1999-09-27
IL114715A (en) 1997-01-10
RU1826966C (ru) 1993-07-07
EP0385658B1 (en) 1994-12-28
HU209481B (en) 1994-06-28
IE65769B1 (en) 1995-11-15
HUT65268A (en) 1994-05-02
CA2362972A1 (en) 1990-08-27
CA2010542C (en) 2002-05-14

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee