HU179443B - Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines - Google Patents

Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Info

Publication number
HU179443B
HU179443B HU79CI1932A HUCI001932A HU179443B HU 179443 B HU179443 B HU 179443B HU 79CI1932 A HU79CI1932 A HU 79CI1932A HU CI001932 A HUCI001932 A HU CI001932A HU 179443 B HU179443 B HU 179443B
Authority
HU
Hungary
Prior art keywords
square bracket
closed
square
pyrimidines
bracket
Prior art date
Application number
HU79CI1932A
Other languages
English (en)
Hungarian (hu)
Inventor
Istvan Hermecz
Tibor Breining
Arpadne Vasvari
Agnes Horvath
Zoltan Meszaros
Istvan Bitter
Jozsef Koekoesi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to HU79CI1932A priority Critical patent/HU179443B/hu
Priority to IL59967A priority patent/IL59967A/xx
Priority to GR61852A priority patent/GR68518B/el
Priority to DE19803017564 priority patent/DE3017564A1/de
Priority to SE8003479A priority patent/SE441747B/sv
Priority to CS803258A priority patent/CS241025B2/cs
Priority to SU802920002A priority patent/SU1151210A3/ru
Priority to NL8002678A priority patent/NL8002678A/nl
Priority to FR8010481A priority patent/FR2456101A1/fr
Priority to CH366380A priority patent/CH646971A5/de
Priority to IT67719/80A priority patent/IT1133085B/it
Priority to JP6161680A priority patent/JPS5615286A/ja
Priority to DK204680A priority patent/DK204680A/da
Priority to CA000351662A priority patent/CA1141379A/en
Priority to LU82437A priority patent/LU82437A1/fr
Priority to GB8015469A priority patent/GB2051048B/en
Priority to FI801512A priority patent/FI68825C/fi
Priority to AT0247580A priority patent/AT377261B/de
Priority to NO801378A priority patent/NO152607C/no
Priority to PT71213A priority patent/PT71213A/pt
Priority to BE0/200550A priority patent/BE883217A/fr
Priority to PL1980224163A priority patent/PL124035B1/pl
Priority to DD80221053A priority patent/DD150605A5/de
Priority to ES491896A priority patent/ES491896A0/es
Publication of HU179443B publication Critical patent/HU179443B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
HU79CI1932A 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines HU179443B (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines
IL59967A IL59967A (en) 1979-05-11 1980-05-01 Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds and a process for their preparation
GR61852A GR68518B (no) 1979-05-11 1980-05-03
DE19803017564 DE3017564A1 (de) 1979-05-11 1980-05-08 Geminale dihalogenderivate kondensierter pyrimidin-4-on-verbindungen, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische kompositionen
SE8003479A SE441747B (sv) 1979-05-11 1980-05-08 Geminala dihalogenderivat av kondenserade pyrimidin-4-on-foreningar
CS803258A CS241025B2 (en) 1979-05-11 1980-05-08 Method of fussed pyrimidine-4-ons' dihalogenated derivatives production
SU802920002A SU1151210A3 (ru) 1979-05-11 1980-05-08 Способ получени геминальных дигалоидных производных конденсированных пиримидин-4-онов,рацематов или оптически активных антиподов
NL8002678A NL8002678A (nl) 1979-05-11 1980-05-09 Tweeling dihalogeenderivaten van gecondenseerde pyrimidine-4-onverbindingen, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze verbindingen bevatten.
FR8010481A FR2456101A1 (fr) 1979-05-11 1980-05-09 Derives dihalogenes geminaux de pyrimidin-4-one condensees, procede pour leur preparation et compositions pharmaceutiques les contenant
CH366380A CH646971A5 (de) 1979-05-11 1980-05-09 Dihalogen-substituierte anelierte pyrimidin-4-on-derivate und verfahren zu ihrer herstellung.
IT67719/80A IT1133085B (it) 1979-05-11 1980-05-09 Derivati dialogenati geminali di composti condensati del pirimidin 4 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
JP6161680A JPS5615286A (en) 1979-05-11 1980-05-09 Zwitter dihalogen derivative of condensed pyrimidinee44one compound* its manufacture and drug composition containing same
DK204680A DK204680A (da) 1979-05-11 1980-05-09 Geminale dihalogenderivater af kondenserede pyrimidin-4-oner deres fremstilling og anvendelse
CA000351662A CA1141379A (en) 1979-05-11 1980-05-09 Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds, process for their preparation and pharmaceutical compositions containing them
LU82437A LU82437A1 (fr) 1979-05-11 1980-05-09 Derives dihalogenes gemines de composes de pyrimidine-one 4 condenses,procede de preparation et compositions pharmaceutiques contenant ceux-ci
GB8015469A GB2051048B (en) 1979-05-11 1980-05-09 Geminal dihalogen derivatives of condensed pyrimidin-4-one compounds their preparation and pharmaceutical compositions containing them
FI801512A FI68825C (fi) 1979-05-11 1980-05-09 Geminala dihalogenderivat av kondenserade pyrimidin-4-oner vilka aer mellanprodukter vid framstaellning av terapeutiskt anaendbara 9-aminopyrido(1,2-a)pyrimidin- och 9-hydratsono- 6,,8,9-tetrahydro-4h-pyrido(1,2-a)pyrimidinderivat
AT0247580A AT377261B (de) 1979-05-11 1980-05-09 Verfahren zur herstellung von neuen kondensierten pyrimidin-4-on-derivaten und von deren salzen und optischen antipoden
NO801378A NO152607C (no) 1979-05-11 1980-05-09 Utgangsmaterialer for anvendelse ved fremstilling av terapeutisk aktive pyrimidinderivater
PT71213A PT71213A (en) 1979-05-11 1980-05-09 Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds process for their preparation and pharmaceutical compositions containing them
BE0/200550A BE883217A (fr) 1979-05-11 1980-05-09 Derives dihalogenes geminaux de pyrimidin-4-one condensees, procede pour leur preparation et compositions pharmaceutiques les contenant
PL1980224163A PL124035B1 (en) 1979-05-11 1980-05-10 Process for preparing novel,substituted halo derivatives of pyrido/1,2-a/pyrimidines,pyrrol/1,2-a/pyrimidines and pyrimido/1,2-a/azepines
DD80221053A DD150605A5 (de) 1979-05-11 1980-05-12 Verfahren zur herstellung dihalogen-substituierter kondensierter pyrimidin-4-on-derivate
ES491896A ES491896A0 (es) 1979-05-11 1980-05-12 Procedimiento de preparar derivados dihalogenicos geminales

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (1)

Publication Number Publication Date
HU179443B true HU179443B (en) 1982-10-28

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Country Status (24)

Country Link
JP (1) JPS5615286A (no)
AT (1) AT377261B (no)
BE (1) BE883217A (no)
CA (1) CA1141379A (no)
CH (1) CH646971A5 (no)
CS (1) CS241025B2 (no)
DD (1) DD150605A5 (no)
DE (1) DE3017564A1 (no)
DK (1) DK204680A (no)
ES (1) ES491896A0 (no)
FI (1) FI68825C (no)
FR (1) FR2456101A1 (no)
GB (1) GB2051048B (no)
GR (1) GR68518B (no)
HU (1) HU179443B (no)
IL (1) IL59967A (no)
IT (1) IT1133085B (no)
LU (1) LU82437A1 (no)
NL (1) NL8002678A (no)
NO (1) NO152607C (no)
PL (1) PL124035B1 (no)
PT (1) PT71213A (no)
SE (1) SE441747B (no)
SU (1) SU1151210A3 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
GR68518B (no) 1982-01-11
IL59967A0 (en) 1980-07-31
NO152607B (no) 1985-07-15
DD150605A5 (de) 1981-09-09
CS241025B2 (en) 1986-03-13
DK204680A (da) 1980-11-12
BE883217A (fr) 1980-09-01
LU82437A1 (fr) 1980-07-31
IT8067719A0 (it) 1980-05-09
IL59967A (en) 1984-05-31
SU1151210A3 (ru) 1985-04-15
ES8102570A1 (es) 1981-02-16
SE8003479L (sv) 1980-11-12
GB2051048A (en) 1981-01-14
NL8002678A (nl) 1980-11-13
FI68825B (fi) 1985-07-31
NO152607C (no) 1985-10-23
FR2456101A1 (fr) 1980-12-05
IT1133085B (it) 1986-07-09
DE3017564A1 (de) 1980-11-13
SE441747B (sv) 1985-11-04
NO801378L (no) 1980-11-12
FR2456101B1 (no) 1985-04-05
PL224163A1 (no) 1981-02-13
FI68825C (fi) 1985-11-11
PL124035B1 (en) 1982-12-31
ATA247580A (de) 1984-07-15
PT71213A (en) 1980-06-01
CA1141379A (en) 1983-02-15
ES491896A0 (es) 1981-02-16
FI801512A (fi) 1980-11-12
CH646971A5 (de) 1984-12-28
AT377261B (de) 1985-02-25
JPS5615286A (en) 1981-02-14
GB2051048B (en) 1983-01-19
CS325880A2 (en) 1985-06-13

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