HU0100146D0 - 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, process for the preparation thereof and use thereof - Google Patents
3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, process for the preparation thereof and use thereofInfo
- Publication number
- HU0100146D0 HU0100146D0 HU0100146A HUP0100146A HU0100146D0 HU 0100146 D0 HU0100146 D0 HU 0100146D0 HU 0100146 A HU0100146 A HU 0100146A HU P0100146 A HUP0100146 A HU P0100146A HU 0100146 D0 HU0100146 D0 HU 0100146D0
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- pentylidene
- benzofuran
- nitro
- hydroxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- RJMPDGNCDFVLHH-UHFFFAOYSA-N 3-(1-hydroxypentylidene)-5-nitro-1-benzofuran-2-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=C(O)CCCC)C(=O)OC2=C1 RJMPDGNCDFVLHH-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0000523A FR2803846B1 (fr) | 2000-01-17 | 2000-01-17 | 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation |
Publications (3)
Publication Number | Publication Date |
---|---|
HU0100146D0 true HU0100146D0 (en) | 2001-03-28 |
HUP0100146A2 HUP0100146A2 (hu) | 2002-01-28 |
HUP0100146A3 HUP0100146A3 (en) | 2003-07-28 |
Family
ID=8845968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0100146A HUP0100146A3 (en) | 2000-01-17 | 2001-01-15 | 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, process for its preparation and use thereof |
Country Status (13)
Country | Link |
---|---|
US (2) | US6515147B2 (hu) |
EP (1) | EP1116719B1 (hu) |
JP (1) | JP4408578B2 (hu) |
KR (1) | KR100788529B1 (hu) |
CN (1) | CN1204133C (hu) |
AT (1) | ATE292630T1 (hu) |
DE (1) | DE60109829T2 (hu) |
DK (1) | DK1116719T3 (hu) |
ES (1) | ES2238408T3 (hu) |
FR (1) | FR2803846B1 (hu) |
HU (1) | HUP0100146A3 (hu) |
NO (1) | NO327039B1 (hu) |
TW (1) | TW564246B (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10237819A1 (de) * | 2002-08-19 | 2004-03-04 | Bayer Ag | 5-Nitrobenzofurane |
FR2864536B1 (fr) | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
GB0719180D0 (en) | 2007-10-02 | 2007-11-14 | Cambrex Karlskoga Ab | New process |
AR072950A1 (es) | 2008-04-17 | 2010-10-06 | Sanofi Aventis | Uso de dronedarona para la preparacion de un medicamento para uso en la prevencion de la hospitalizacion cardiovascular o de la mortalidad, composicion farmaceutica, articulo de fabricacion y envase |
FR2930149B1 (fr) * | 2008-04-17 | 2011-02-18 | Sanofi Aventis | Association de dronedarone avec au moins un diuretique, son application en therapeutique |
EP2116239A1 (en) * | 2008-04-29 | 2009-11-11 | Sanofi-Aventis | Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment |
EP2246341A1 (en) | 2009-01-23 | 2010-11-03 | Lonza Ltd. | Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans |
CN102276561A (zh) * | 2010-06-09 | 2011-12-14 | 江苏恒瑞医药股份有限公司 | 决奈达隆及其盐的制备方法 |
US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248401A (en) * | 1966-04-26 | Diethylaminoe hoxybenzoyl benzofurans | ||
US4252817A (en) * | 1975-03-12 | 1981-02-24 | Sandoz Ltd. | Substituted-2,3-dihydrobenzofuran-2-ones |
FR2642755B1 (hu) * | 1989-02-07 | 1993-11-05 | Sanofi | |
FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
GB9416219D0 (en) * | 1994-08-11 | 1994-10-05 | Karobio Ab | Receptor ligands |
-
2000
- 2000-01-17 FR FR0000523A patent/FR2803846B1/fr not_active Expired - Fee Related
-
2001
- 2001-01-10 TW TW090100495A patent/TW564246B/zh not_active IP Right Cessation
- 2001-01-15 ES ES01810033T patent/ES2238408T3/es not_active Expired - Lifetime
- 2001-01-15 DK DK01810033T patent/DK1116719T3/da active
- 2001-01-15 DE DE60109829T patent/DE60109829T2/de not_active Expired - Lifetime
- 2001-01-15 EP EP01810033A patent/EP1116719B1/en not_active Expired - Lifetime
- 2001-01-15 HU HU0100146A patent/HUP0100146A3/hu unknown
- 2001-01-15 AT AT01810033T patent/ATE292630T1/de active
- 2001-01-16 JP JP2001007465A patent/JP4408578B2/ja not_active Expired - Fee Related
- 2001-01-16 KR KR1020010002333A patent/KR100788529B1/ko not_active IP Right Cessation
- 2001-01-16 NO NO20010265A patent/NO327039B1/no not_active IP Right Cessation
- 2001-01-17 US US09/761,452 patent/US6515147B2/en not_active Ceased
- 2001-01-17 CN CNB01101296XA patent/CN1204133C/zh not_active Expired - Fee Related
-
2005
- 2005-02-03 US US11/050,627 patent/USRE39755E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100788529B1 (ko) | 2007-12-24 |
HUP0100146A3 (en) | 2003-07-28 |
EP1116719A2 (en) | 2001-07-18 |
FR2803846A1 (fr) | 2001-07-20 |
CN1204133C (zh) | 2005-06-01 |
DK1116719T3 (da) | 2005-07-18 |
DE60109829D1 (de) | 2005-05-12 |
TW564246B (en) | 2003-12-01 |
JP4408578B2 (ja) | 2010-02-03 |
EP1116719A3 (en) | 2001-10-24 |
HUP0100146A2 (hu) | 2002-01-28 |
US6515147B2 (en) | 2003-02-04 |
KR20010076278A (ko) | 2001-08-11 |
ES2238408T3 (es) | 2005-09-01 |
JP2001233870A (ja) | 2001-08-28 |
ATE292630T1 (de) | 2005-04-15 |
USRE39755E1 (en) | 2007-07-31 |
NO20010265L (no) | 2001-07-18 |
US20010012900A1 (en) | 2001-08-09 |
FR2803846B1 (fr) | 2002-04-05 |
CN1306000A (zh) | 2001-08-01 |
NO20010265D0 (no) | 2001-01-16 |
NO327039B1 (no) | 2009-04-06 |
EP1116719B1 (en) | 2005-04-06 |
DE60109829T2 (de) | 2006-01-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |