HU00552A9 - Alpha-amidating enzyme compositions and processes for their production and use - Google Patents

Alpha-amidating enzyme compositions and processes for their production and use

Info

Publication number
HU00552A9
HU00552A9 HU95P/P00552P HUPP00552P HU00552A9 HU 00552 A9 HU00552 A9 HU 00552A9 HU PP00552 P HUPP00552 P HU PP00552P HU 00552 A9 HU00552 A9 HU 00552A9
Authority
HU
Hungary
Prior art keywords
stone
weight
calcium
thermals
snow
Prior art date
Application number
HU95P/P00552P
Other languages
English (en)
Inventor
Nozer M Mehta
James P Gilligan
Barry N Jones
Arthur H Bertelsen
Original Assignee
Unigene Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22196693&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU00552(A9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Unigene Lab Inc filed Critical Unigene Lab Inc
Publication of HU00552A9 publication Critical patent/HU00552A9/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
    • C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány kalciűmszűlfát és kőhóhőmők keverékéből előállítőttkötőanyag hidraűlikűs kötésű, önterülő rűgalmas terítőréteghez.Jellegzetessége, hőgy kalciűmszűlfát és kőhóhőmők mellett a keverékCA-ként számításba vett reaktív alűminátőkat is tartalmaz, amelyekadőtt esetben részben mészhidráttal helyettesíthetők, és a keverékkalciűmszűlfát (kőhóhőmők) reaktív alűminátők hárőmalkőtós diagramjaegy ablakban a kalciűmszűlfát-kőhóhőmők tengelyen a CaSO4-bankifejezett kalciűmszűlfáttal 35-től 70 súly%-ig, a reaktív alűminátőkrészaránya pedig a megfelelő tengelyen 0,5-től 5 súly%-ig terjed, ésúgy van meghatárőzva, hőgy egy hárőm súlyrész kvarchőmőkból és egysúlyrész kötőanyagból álló keverékből készült szabványős habarcsprizma28 napős kőrában, amelyből előzetes nedves, illetve vizes tárőlás űtán21 napig tárőlták 20 řC hőmérsékleten és 65% relatív légnedvességmellett, kevesebb, mint 0,3 mm/m, előnyösen kevesebb, mint 0,2 mm/mzsűgőrődást műtat. ŕ
HU95P/P00552P 1987-08-14 1995-06-29 Alpha-amidating enzyme compositions and processes for their production and use HU00552A9 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/086,161 US6319685B1 (en) 1984-09-27 1987-08-14 Alpha-amidating enzyme compositions and processes for their production and use

Publications (1)

Publication Number Publication Date
HU00552A9 true HU00552A9 (en) 1995-10-30

Family

ID=22196693

Family Applications (3)

Application Number Title Priority Date Filing Date
HU884132A HU213227B (en) 1987-08-14 1988-08-09 Method for producing alfa-amidating enzim composition, host cell containing the dna coding for the enzim, and peptidil amids
HU94P/P00552P HU212071A9 (en) 1987-08-14 1994-07-01 Alpha-amidating enzyme compositions and processes for their production and use
HU95P/P00552P HU00552A9 (en) 1987-08-14 1995-06-29 Alpha-amidating enzyme compositions and processes for their production and use

Family Applications Before (2)

Application Number Title Priority Date Filing Date
HU884132A HU213227B (en) 1987-08-14 1988-08-09 Method for producing alfa-amidating enzim composition, host cell containing the dna coding for the enzim, and peptidil amids
HU94P/P00552P HU212071A9 (en) 1987-08-14 1994-07-01 Alpha-amidating enzyme compositions and processes for their production and use

Country Status (13)

Country Link
US (1) US6319685B1 (hu)
EP (2) EP0529742B1 (hu)
JP (1) JP2979172B2 (hu)
KR (1) KR0136611B1 (hu)
AT (1) ATE198355T1 (hu)
CA (1) CA1341454C (hu)
DE (1) DE3856446T2 (hu)
DK (1) DK175538B1 (hu)
FI (1) FI883722A (hu)
HU (3) HU213227B (hu)
LT (1) LT4029B (hu)
NO (1) NO883592L (hu)
RU (2) RU2080385C1 (hu)

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US4708934A (en) * 1984-09-27 1987-11-24 Unigene Laboratories, Inc. α-amidation enzyme
US6319685B1 (en) 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US5871995A (en) * 1989-08-15 1999-02-16 Shiseido Company, Ltd. Purified enzymes participating in C-terminal amidation
DK0465404T3 (da) * 1990-06-01 1995-12-18 Ciba Geigy Ag Peptidylhydroxylglycin-N-C-lyase og DNA, som koder derfor
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides
DK67691D0 (da) * 1991-03-01 1991-04-15 Carlbiotech Ltd As Enzymatisk fremgangsmaade til c-terminal modificering af peptider og mellemprodukter til brug ved fremgangsmaaden
WO1996017941A2 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
ES2375330T3 (es) * 1997-04-16 2012-02-28 Unigene Laboratories, Inc. Expresión directa de péptidos en medios de cultivo.
WO2004011652A1 (ja) 2002-07-26 2004-02-05 Ajinomoto Co., Inc. トリペプチド以上のペプチドの製造方法
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US7648965B2 (en) * 2004-05-14 2010-01-19 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US7531518B2 (en) * 2004-05-14 2009-05-12 Unigene Laboratories Inc. Method for fostering bone formation and preservation
US20060089723A1 (en) * 2004-10-25 2006-04-27 Murphy Kieran P Method for bone augmentation
US7445911B2 (en) * 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids
PA8660701A1 (es) 2005-02-04 2006-09-22 Pfizer Prod Inc Agonistas de pyy y sus usos
US20060293667A1 (en) * 2005-05-19 2006-12-28 Agnes Vignery Bone implant device and methods of using same
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
AU2010206614B2 (en) 2009-01-22 2015-03-26 Keybioscience Ag Treatment for obesity
RU2012126101A (ru) 2009-11-23 2013-12-27 АМИЛИН ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи,США Полипептидный конъюгат
TW201138808A (en) 2010-05-03 2011-11-16 Bristol Myers Squibb Co Serum albumin binding molecules
PT2621519T (pt) 2010-09-28 2017-10-04 Aegerion Pharmaceuticals Inc Polipéptido de fusão de leptina-abd com duração de ação melhorada
BR112013007442A2 (pt) 2010-09-28 2019-09-24 Amylin Pharmaceuticals Llc polipeptídeos construídos tendo duração de ação realçada
EP3533457B1 (en) 2011-06-15 2021-08-11 ResoTher Pharma ApS Anti-inflammatory pharmaceutical products
WO2013009539A1 (en) 2011-07-08 2013-01-17 Amylin Pharmaceuticals, Inc. Engineered polypeptides having enhanced duration of action and reduced immunogenicity
WO2013009545A1 (en) 2011-07-08 2013-01-17 Amylin Pharmaceuticals, Inc. Engineered polypeptides having enhanced duration of action with reduced immunogenicity
LT3095484T (lt) 2011-11-02 2018-08-10 Keybioscience Ag Kalcitonino mimetikai, skirti ligų ir sutrikimų gydymui
US9533022B2 (en) 2011-11-02 2017-01-03 KeyBioscience A/S Peptide analogs for treating diseases and disorders
KR102019911B1 (ko) 2011-11-02 2019-09-09 키바이오사이언스 아게 질병 및 장애 치료용 펩타이드 유사체
LT3068796T (lt) 2013-11-14 2018-05-10 Keybioscience Ag Kalcitonino mimetikai, skirti ligų ir sutrikimų gydymui
CA2932408A1 (en) 2013-12-02 2015-06-11 Stealth Biotherapeutics Corp Compositions and methods for treating vitiligo
WO2015183995A2 (en) 2014-05-28 2015-12-03 Stealth Peptides International, Inc. Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof
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Also Published As

Publication number Publication date
DE3856446D1 (de) 2001-02-01
AU2057688A (en) 1989-02-16
ATE198355T1 (de) 2001-01-15
NO883592L (no) 1989-02-15
LT4029B (en) 1996-08-26
NO883592D0 (no) 1988-08-12
FI883722A (fi) 1989-02-15
AU629795B2 (en) 1992-10-15
EP0529742B1 (en) 2000-12-27
DK448988A (da) 1989-02-15
JPH02104281A (ja) 1990-04-17
DE3856446T2 (de) 2001-07-12
KR890003947A (ko) 1989-04-19
DK448988D0 (da) 1988-08-11
HU213227B (en) 1997-07-28
LTIP1656A (en) 1995-07-25
EP0529742A1 (en) 1993-03-03
DK175538B1 (da) 2004-11-29
RU2080385C1 (ru) 1997-05-27
HU212071A9 (en) 1996-02-28
EP0308067A2 (en) 1989-03-22
JP2979172B2 (ja) 1999-11-15
US6319685B1 (en) 2001-11-20
RU2252961C2 (ru) 2005-05-27
FI883722A0 (fi) 1988-08-10
CA1341454C (en) 2004-04-20
EP0308067A3 (en) 1989-07-26
KR0136611B1 (ko) 1998-04-25

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