HRP950403B1 - Inhalation composition - Google Patents

Inhalation composition

Info

Publication number
HRP950403B1
HRP950403B1 HR950403A HRP950403A HRP950403B1 HR P950403 B1 HRP950403 B1 HR P950403B1 HR 950403 A HR950403 A HR 950403A HR P950403 A HRP950403 A HR P950403A HR P950403 B1 HRP950403 B1 HR P950403B1
Authority
HR
Croatia
Prior art keywords
mum
inhalation composition
particle size
active compound
mean particle
Prior art date
Application number
HR950403A
Other languages
English (en)
Inventor
Werner Sarlikiotis
Anne H De Boer
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of HRP950403A2 publication Critical patent/HRP950403A2/hr
Publication of HRP950403B1 publication Critical patent/HRP950403B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
HR950403A 1994-07-16 1995-07-14 Inhalation composition HRP950403B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425255A DE4425255A1 (de) 1994-07-16 1994-07-16 Formulierung zur inhalativen Applikation

Publications (2)

Publication Number Publication Date
HRP950403A2 HRP950403A2 (en) 1997-10-31
HRP950403B1 true HRP950403B1 (en) 2001-12-31

Family

ID=6523404

Family Applications (1)

Application Number Title Priority Date Filing Date
HR950403A HRP950403B1 (en) 1994-07-16 1995-07-14 Inhalation composition

Country Status (32)

Country Link
US (1) US6284287B1 (no)
EP (1) EP0771189B1 (no)
JP (1) JP3011770B2 (no)
KR (1) KR970704422A (no)
CN (1) CN1234344C (no)
AT (1) ATE204160T1 (no)
AU (1) AU703924B2 (no)
BR (1) BR9508287A (no)
CA (1) CA2195065C (no)
CZ (1) CZ290921B6 (no)
DE (2) DE4425255A1 (no)
DK (1) DK0771189T3 (no)
ES (1) ES2162927T3 (no)
FI (1) FI118790B (no)
HR (1) HRP950403B1 (no)
HU (1) HU223069B1 (no)
IL (1) IL114596A (no)
IS (1) IS1889B (no)
MX (1) MX9700034A (no)
MY (1) MY115688A (no)
NO (1) NO315894B1 (no)
NZ (1) NZ289117A (no)
PL (1) PL186153B1 (no)
PT (1) PT771189E (no)
RU (1) RU2140260C1 (no)
SK (1) SK282764B6 (no)
TR (1) TR199500856A2 (no)
TW (1) TW475904B (no)
UA (1) UA29507C2 (no)
WO (1) WO1996002231A1 (no)
YU (1) YU49279B (no)
ZA (1) ZA955892B (no)

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ITMI991582A1 (it) * 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
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PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009468D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
ES2288167T3 (es) * 2000-04-17 2008-01-01 Vectura Limited Formulaciones para usar en dispositivos inhaladores.
RS50197B (sr) 2000-10-12 2009-05-06 Boehringer Ingelheim Pharma Gmbh. & Co.Kg., Novi tiotropiumski preparati- koji sadrže prah za inhaliranje
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
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US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
US7947742B2 (en) * 2002-06-28 2011-05-24 Civitas Therapeutics, Inc. Inhalable epinephrine
EP1599209B1 (en) * 2002-08-21 2011-08-17 Norton Healthcare Limited Inhalation composition
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
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DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
CA2526475A1 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
BRPI0509348A (pt) 2004-04-21 2007-09-11 Innovata Biomed Ltd inalador
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
EP1944018A1 (en) * 2007-01-10 2008-07-16 CHIESI FARMACEUTICI S.p.A. Micronised particles of low-dosage strength active agents for powder formulations for inhalation
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US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US20100272811A1 (en) * 2008-07-23 2010-10-28 Alkermes,Inc. Complex of trospium and pharmaceutical compositions thereof
WO2010014827A2 (en) * 2008-07-30 2010-02-04 Stc.Unm Formulations containing large-size carrier particles for dry powder inhalation aerosols
CN103998053B9 (zh) 2011-12-13 2020-07-21 皮里斯制药有限公司 通过抑制il-4和/或il-13与其各自的受体结合来预防或治疗某些障碍的方法
KR20200015828A (ko) * 2012-02-28 2020-02-12 아이슈티카 홀딩스 인코포레이티드. 흡입용 약제학적 조성물
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Also Published As

Publication number Publication date
IL114596A0 (en) 1995-11-27
UA29507C2 (uk) 2000-11-15
NO970068L (no) 1997-01-08
CZ12697A3 (cs) 1998-02-18
FI970164A (fi) 1997-01-15
NZ289117A (en) 1998-06-26
HU223069B1 (hu) 2004-03-01
SK5697A3 (en) 1997-06-04
TW475904B (en) 2002-02-11
PL318649A1 (en) 1997-07-07
DE4425255A1 (de) 1996-01-18
MY115688A (en) 2003-08-30
EP0771189A1 (de) 1997-05-07
ES2162927T3 (es) 2002-01-16
WO1996002231A1 (de) 1996-02-01
YU46095A (sh) 1998-07-10
BR9508287A (pt) 1998-07-21
MX9700034A (es) 1997-12-31
AU2886295A (en) 1996-02-16
JP3011770B2 (ja) 2000-02-21
CA2195065A1 (en) 1996-02-01
HUT76807A (en) 1997-11-28
CA2195065C (en) 2002-02-19
PL186153B1 (pl) 2003-11-28
CZ290921B6 (cs) 2002-11-13
NO315894B1 (no) 2003-11-10
SK282764B6 (sk) 2002-12-03
AU703924B2 (en) 1999-04-01
NO970068D0 (no) 1997-01-08
IL114596A (en) 2000-02-29
EP0771189B1 (de) 2001-08-16
HRP950403A2 (en) 1997-10-31
YU49279B (sh) 2005-03-15
HU9700131D0 (en) 1997-02-28
KR970704422A (ko) 1997-09-06
TR199500856A2 (tr) 1996-06-21
DE59509518D1 (de) 2001-09-20
IS1889B (is) 2003-09-19
FI118790B (fi) 2008-03-31
PT771189E (pt) 2002-02-28
FI970164A0 (fi) 1997-01-15
ZA955892B (en) 1996-02-19
US6284287B1 (en) 2001-09-04
RU2140260C1 (ru) 1999-10-27
JPH10502647A (ja) 1998-03-10
IS4396A (is) 1996-12-13
CN1156960A (zh) 1997-08-13
CN1234344C (zh) 2006-01-04
ATE204160T1 (de) 2001-09-15
DK0771189T3 (da) 2001-11-26

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Owner name: SOFOTEC GMBH & CO. KG, DE

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