ES2162927T3 - Formulacion para la aplicacion por inhalacion. - Google Patents

Formulacion para la aplicacion por inhalacion.

Info

Publication number
ES2162927T3
ES2162927T3 ES95924299T ES95924299T ES2162927T3 ES 2162927 T3 ES2162927 T3 ES 2162927T3 ES 95924299 T ES95924299 T ES 95924299T ES 95924299 T ES95924299 T ES 95924299T ES 2162927 T3 ES2162927 T3 ES 2162927T3
Authority
ES
Spain
Prior art keywords
mum
inhalation
formulation
application
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95924299T
Other languages
English (en)
Inventor
Werner Sarlikiotis
Boer Anne H De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sofotec GmbH
Original Assignee
Sofotec GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sofotec GmbH filed Critical Sofotec GmbH
Application granted granted Critical
Publication of ES2162927T3 publication Critical patent/ES2162927T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

SE DESCRIBE UNA FORMULACION FARMACEUTICA PARA UTILIZARSE EN INHALADORES EN POLVO. SE COMPONE DE UN CUERPO BASE Y ADHERIDO A EL UN MEDICAMENTO O UNA MEZCLA DE MEDICAMENTOS. LA FORMULACION ES FACILMENTE REDISPERSABLE, DE TAL MANERA QUE SE DESCOMPONE RAPIDAMENTE EN PARTICULAS CAPACES DE PASAR A LOS PULMONES. LA FORMULACION SE EMPLEA PARA LA OBTENCION DE MEDICAMENTOS.
ES95924299T 1994-07-16 1995-06-21 Formulacion para la aplicacion por inhalacion. Expired - Lifetime ES2162927T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425255A DE4425255A1 (de) 1994-07-16 1994-07-16 Formulierung zur inhalativen Applikation

Publications (1)

Publication Number Publication Date
ES2162927T3 true ES2162927T3 (es) 2002-01-16

Family

ID=6523404

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95924299T Expired - Lifetime ES2162927T3 (es) 1994-07-16 1995-06-21 Formulacion para la aplicacion por inhalacion.

Country Status (32)

Country Link
US (1) US6284287B1 (es)
EP (1) EP0771189B1 (es)
JP (1) JP3011770B2 (es)
KR (1) KR970704422A (es)
CN (1) CN1234344C (es)
AT (1) ATE204160T1 (es)
AU (1) AU703924B2 (es)
BR (1) BR9508287A (es)
CA (1) CA2195065C (es)
CZ (1) CZ290921B6 (es)
DE (2) DE4425255A1 (es)
DK (1) DK0771189T3 (es)
ES (1) ES2162927T3 (es)
FI (1) FI118790B (es)
HR (1) HRP950403B1 (es)
HU (1) HU223069B1 (es)
IL (1) IL114596A (es)
IS (1) IS1889B (es)
MX (1) MX9700034A (es)
MY (1) MY115688A (es)
NO (1) NO315894B1 (es)
NZ (1) NZ289117A (es)
PL (1) PL186153B1 (es)
PT (1) PT771189E (es)
RU (1) RU2140260C1 (es)
SK (1) SK282764B6 (es)
TR (1) TR199500856A2 (es)
TW (1) TW475904B (es)
UA (1) UA29507C2 (es)
WO (1) WO1996002231A1 (es)
YU (1) YU49279B (es)
ZA (1) ZA955892B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
EP0876814A1 (en) * 1997-05-07 1998-11-11 "PHARLYSE", Société Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it
IT1309592B1 (it) 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
ITMI991582A1 (it) * 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
US7022311B1 (en) 1999-10-12 2006-04-04 Kaken Pharmaceutical Co., Ltd. Powdery inhalational preparations and process for producing the same
GB0008660D0 (en) * 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
GB0009468D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
NZ521972A (en) * 2000-04-17 2004-06-25 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
KR100488644B1 (ko) 2000-10-12 2005-05-11 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 티오트로퓸을 함유하는 신규 흡입용 산제
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
US7947742B2 (en) * 2002-06-28 2011-05-24 Civitas Therapeutics, Inc. Inhalable epinephrine
US8273331B2 (en) * 2002-08-21 2012-09-25 Norton Healthcare Ltd. Inhalation compositions
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US7763280B2 (en) * 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
ATE510174T1 (de) 2003-05-21 2011-06-15 Alexza Pharmaceuticals Inc Schlag gezündete unabhängige heizeinheit
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
CA2562386C (en) 2004-04-21 2014-11-18 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
EP1944018A1 (en) * 2007-01-10 2008-07-16 CHIESI FARMACEUTICI S.p.A. Micronised particles of low-dosage strength active agents for powder formulations for inhalation
EP2120875B1 (en) * 2007-02-11 2018-07-11 Map Pharmaceuticals Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
ES2594867T3 (es) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Unidad de calentamiento para usar en un dispositivo de administración de fármaco
US20100272811A1 (en) * 2008-07-23 2010-10-28 Alkermes,Inc. Complex of trospium and pharmaceutical compositions thereof
JP5705112B2 (ja) * 2008-07-30 2015-04-22 エスティーシー．ユーエヌエム ドライパウダー吸入エアロゾル用の大径キャリア粒子を含む製剤
HUE042720T2 (hu) 2011-12-13 2019-07-29 Pieris Pharmaceuticals Gmbh Eljárás bizonyos rendellenességek megelõzésére vagy kezelésére IL-4 és/vagy IL-13 saját receptorához történõ kötõdésének gátlása révén
SG10201703243QA (en) * 2012-02-28 2017-06-29 Iceutica Holdings Inc Inhalable pharmaceutical compositions
EP3175842B1 (en) 2015-12-03 2019-12-11 Alfred E. Tiefenbacher (GmbH & Co. KG) Dry powder mixing process
WO2021058454A1 (en) 2019-09-24 2021-04-01 Chiesi Farmaceutici S.P.A. Novel carrier particles for dry powder formulations for inhalation

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860618A (en) 1967-08-08 1975-01-14 Philip Saxton Hartley Chromone
US3957965A (en) 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
GB1410588A (en) * 1971-08-10 1975-10-22 Fisons Ltd Composition
DE2535258C2 (de) * 1974-08-10 1993-06-03 Fisons Plc, Ipswich, Suffolk Inhalierbares Medikament in Pelletform
GB1520247A (en) 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
GB1520248A (en) 1975-07-24 1978-08-02 Fisons Ltd Sodium cromoglycate containing medicament
US4161516A (en) 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
IL57956A (en) 1975-07-28 1980-07-31 Fisons Ltd Disodium cromoglycate in pellet or granule form having a low loose bulk density
IL51233A (en) 1975-07-28 1980-07-31 Fisons Ltd Pharmaceutical compositions in the form of soft pellets or granules
AU522792B2 (en) 1977-07-19 1982-06-24 Fisons Plc Pressure pack formulation
GB1571629A (en) 1977-11-30 1980-07-16 Fisons Ltd Pharmaceutical compositions containing beclomethasone dipropionate
GB2077100B (en) * 1980-04-30 1985-04-24 Fisons Ltd Pharmaceutical compositions containing cromoglycates
IT1204826B (it) 1986-03-04 1989-03-10 Chiesi Farma Spa Composizioni farmaceutiche per inalazione
US5376386A (en) 1990-01-24 1994-12-27 British Technology Group Limited Aerosol carriers
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
WO1991011174A1 (en) * 1990-01-25 1991-08-08 The University Of Colorado Foundation, Inc. Method for preventing immune suppression in trauma patients
GB9027968D0 (en) * 1990-12-22 1991-02-13 Fisons Plc Method of treatment
DE4140689B4 (de) 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
TW244350B (es) 1991-12-14 1995-04-01 Hoechst Ag
ES2177544T3 (es) 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers

Also Published As

Publication number Publication date
PL186153B1 (pl) 2003-11-28
ATE204160T1 (de) 2001-09-15
JP3011770B2 (ja) 2000-02-21
EP0771189B1 (de) 2001-08-16
JPH10502647A (ja) 1998-03-10
HU9700131D0 (en) 1997-02-28
NO970068D0 (no) 1997-01-08
TW475904B (en) 2002-02-11
AU2886295A (en) 1996-02-16
CN1234344C (zh) 2006-01-04
US6284287B1 (en) 2001-09-04
WO1996002231A1 (de) 1996-02-01
ZA955892B (en) 1996-02-19
MX9700034A (es) 1997-12-31
FI970164A (fi) 1997-01-15
CA2195065C (en) 2002-02-19
IL114596A0 (en) 1995-11-27
NO315894B1 (no) 2003-11-10
CA2195065A1 (en) 1996-02-01
CN1156960A (zh) 1997-08-13
YU49279B (sh) 2005-03-15
FI970164A0 (fi) 1997-01-15
CZ290921B6 (cs) 2002-11-13
TR199500856A2 (tr) 1996-06-21
NO970068L (no) 1997-01-08
DE4425255A1 (de) 1996-01-18
IL114596A (en) 2000-02-29
UA29507C2 (uk) 2000-11-15
HUT76807A (en) 1997-11-28
HRP950403B1 (en) 2001-12-31
RU2140260C1 (ru) 1999-10-27
PL318649A1 (en) 1997-07-07
SK5697A3 (en) 1997-06-04
DE59509518D1 (de) 2001-09-20
IS1889B (is) 2003-09-19
AU703924B2 (en) 1999-04-01
KR970704422A (ko) 1997-09-06
HU223069B1 (hu) 2004-03-01
NZ289117A (en) 1998-06-26
IS4396A (is) 1996-12-13
EP0771189A1 (de) 1997-05-07
HRP950403A2 (en) 1997-10-31
DK0771189T3 (da) 2001-11-26
CZ12697A3 (cs) 1998-02-18
BR9508287A (pt) 1998-07-21
SK282764B6 (sk) 2002-12-03
YU46095A (sh) 1998-07-10
MY115688A (en) 2003-08-30
FI118790B (fi) 2008-03-31
PT771189E (pt) 2002-02-28

Similar Documents

Publication Publication Date Title
ES2162927T3 (es) Formulacion para la aplicacion por inhalacion.
BRPI0015567B8 (pt) composto, composição farmacêutica, forma de unidade de dosagem, uso da composição farmacêutica e método para preparar uma composição farmacêutica
BR9909192A (pt) Preparações galênicas de meloxicam para administração oral
ES2170069T3 (es) 1-alfa-hidroxiprevitamina d para administracion oral.
BR0115382A (pt) Formulações para liberação controlada de hidrocodona, método de produzir analgesia efetiva, processo de preparação de uma forma farmacêutica de um sólido oral de liberação controlada, liberação controlada da forma farmacêutica oral e uso da forma farmacêutica
CA2335065A1 (en) Pharmaceutical formulations for aerosols with two or more active substances
ES2152966T3 (es) Formas de dosificado farmaceuticas de desleido rapido y procedimiento para su preparacion.
CL2009001682A1 (es) Composición farmacéutica espontáneamente dispersable para administración oral que comprende n-benzoil-estaurosporina; método para incrementar los niveles de biodisponibilidad. (divisional de la solocitud 333-00).
AR004700A1 (es) 1alfa, 26 dihidroxi-d-homo-vitamina d3, una composicion farmaceutica que la comprende, un procedimiento para su preparacion y el uso de los mismos en laelaboracion de un medicamento
ES8307496A1 (es) Procedimiento para la obtencion de una preparacion galenica antagonista al calcio.
GR890100833A (en) Process for the preparation of a compound with gastric inhibitopy effect
AR035006A1 (es) Derivado de naftiridin-dibenzo[a,d]ciclohepteno-10-acetico, composicion farmaceutica, y el uso de dicho derivado para la fabricacion de un medicamento.
ATE234096T1 (de) Pharmazeutische zusammensetzung zur systemischen transdermalen verabreichung mit dem wirkstoff morphin-6-glucuronid
SE7708622L (sv) 2-bensyl-perhydroazepiner, sett for framstellning derav och lekemedel, innehallande dem
BR0010449A (pt) 14beta-h-esteróis, composições farmacêuticas que compreendem os mesmos e uso destes derivados para a preparação de medicamentos reguladores da meiose
ES2064104T3 (es) Procedimiento de preparacion de composiciones farmaceuticas del tipo de liberacion prolongada destinadas a la administracion por via oral.
SE8304818D0 (sv) A medicine having anti-ulcer, spasmolytic and locally anesthetic effect
ES2135424T3 (es) Composicion oral a base de ibuprofeno.
IT1262929B (it) Impiego terapeutico del monosialodiesosil ganglioside gm3 e derivati come agenti anti-angiogenici

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 771189

Country of ref document: ES