HRP20191892T8 - Sublingvalna formulacija riluzola - Google Patents

Sublingvalna formulacija riluzola

Info

Publication number
HRP20191892T8
HRP20191892T8 HRP20191892TT HRP20191892T HRP20191892T8 HR P20191892 T8 HRP20191892 T8 HR P20191892T8 HR P20191892T T HRP20191892T T HR P20191892TT HR P20191892 T HRP20191892 T HR P20191892T HR P20191892 T8 HRP20191892 T8 HR P20191892T8
Authority
HR
Croatia
Prior art keywords
riluzole
sublingual formulation
sublingual
formulation
Prior art date
Application number
HRP20191892TT
Other languages
English (en)
Croatian (hr)
Inventor
Vladimir Coric
Robert M. Berman
Ronald Samuel Vladyka
Amgad SALEH
Danny Yu
Original Assignee
Biohaven Therapeutics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohaven Therapeutics Ltd. filed Critical Biohaven Therapeutics Ltd.
Publication of HRP20191892T1 publication Critical patent/HRP20191892T1/hr
Publication of HRP20191892T8 publication Critical patent/HRP20191892T8/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20191892TT 2014-11-21 2015-11-17 Sublingvalna formulacija riluzola HRP20191892T8 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462083094P 2014-11-21 2014-11-21
EP15823415.3A EP3220891B1 (en) 2014-11-21 2015-11-17 Sublingual formulation of riluzole
PCT/US2015/061114 WO2016081472A1 (en) 2014-11-21 2015-11-17 Sublingual formulation of riluzole

Publications (2)

Publication Number Publication Date
HRP20191892T1 HRP20191892T1 (hr) 2020-01-10
HRP20191892T8 true HRP20191892T8 (hr) 2020-09-18

Family

ID=55085882

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20191892TT HRP20191892T8 (hr) 2014-11-21 2015-11-17 Sublingvalna formulacija riluzola

Country Status (24)

Country Link
US (3) US11660267B2 (enExample)
EP (3) EP3220891B1 (enExample)
JP (3) JP6753860B2 (enExample)
KR (2) KR102811263B1 (enExample)
CN (1) CN107249567B (enExample)
AU (2) AU2015350148B2 (enExample)
BR (1) BR112017010423B1 (enExample)
CA (1) CA2967662A1 (enExample)
CY (1) CY1122469T1 (enExample)
DK (1) DK3220891T3 (enExample)
EA (1) EA038518B1 (enExample)
ES (2) ES2751300T3 (enExample)
HR (1) HRP20191892T8 (enExample)
HU (1) HUE046869T2 (enExample)
IL (2) IL278188B2 (enExample)
LT (1) LT3220891T (enExample)
MX (1) MX368838B (enExample)
PH (1) PH12017500934B1 (enExample)
PL (1) PL3220891T3 (enExample)
PT (1) PT3220891T (enExample)
RS (1) RS59490B1 (enExample)
SG (1) SG11201703896QA (enExample)
SI (1) SI3220891T1 (enExample)
WO (1) WO2016081472A1 (enExample)

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JP7354123B2 (ja) * 2018-02-21 2023-10-02 エイアイ・セラピューティクス・インコーポレーテッド アピリモドとグルタミン酸作動薬を用いた併用療法
BR112020023231A2 (pt) * 2018-05-27 2021-02-23 Biohaven Pharmaceutical Holding Company Ltd. uso de comprimidos desintegrantes orais de riluzol para tratamento de doenças
MX2021001563A (es) * 2018-08-16 2021-06-15 Biohaven Therapeutics Ltd Uso de tabletas de desintegracion oral de riluzol para tratar enfermedades.
JP7716396B2 (ja) * 2019-10-22 2025-07-31 アルビナス・オペレーションズ・インコーポレイテッド 前立腺癌を治療する方法
MX2022014071A (es) 2020-05-09 2023-01-30 Arvinas Operations Inc Metodos para fabricar un compuesto bifuncional, formas ultrapuras del compuesto bifuncional y formas de dosificacion que comprenden el mismo.
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US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
CN113876735B (zh) * 2021-10-20 2023-05-12 陇南市第一人民医院 一种利鲁唑微球制剂及其制备方法
KR102625977B1 (ko) 2021-11-24 2024-01-17 부산대학교 산학협력단 리루졸을 유효성분으로 포함하는 염증성 장질환 예방 또는 치료용 조성물

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Also Published As

Publication number Publication date
BR112017010423B1 (pt) 2023-09-26
IL278188B2 (en) 2025-03-01
EA038518B1 (ru) 2021-09-09
EA201790958A1 (ru) 2018-01-31
BR112017010423A2 (pt) 2017-12-26
CY1122469T1 (el) 2021-01-27
ES2751300T3 (es) 2020-03-31
EP4039247B1 (en) 2025-11-05
SI3220891T1 (sl) 2020-02-28
PL3220891T3 (pl) 2020-08-24
JP2021001173A (ja) 2021-01-07
IL252285B (en) 2020-10-29
JP6753860B2 (ja) 2020-09-09
JP2023065398A (ja) 2023-05-12
DK3220891T3 (da) 2019-11-04
IL278188A (en) 2020-11-30
EP3220891B1 (en) 2019-07-24
US20250114301A1 (en) 2025-04-10
ES2882783T3 (es) 2021-12-02
EP4039247A2 (en) 2022-08-10
EP4039247A3 (en) 2022-11-16
LT3220891T (lt) 2019-11-11
US20210038499A1 (en) 2021-02-11
WO2016081472A1 (en) 2016-05-26
EP3616686B8 (en) 2021-06-23
HRP20191892T1 (hr) 2020-01-10
MX2017006446A (es) 2018-02-12
HUE046869T2 (hu) 2020-04-28
PH12017500934A1 (en) 2017-11-20
IL278188B1 (en) 2024-11-01
AU2015350148A1 (en) 2017-06-15
KR102580378B1 (ko) 2023-09-19
JP2017535613A (ja) 2017-11-30
MX368838B (es) 2019-10-18
US20180153794A1 (en) 2018-06-07
CN107249567A (zh) 2017-10-13
PT3220891T (pt) 2019-10-31
IL252285A0 (en) 2017-07-31
KR20170137032A (ko) 2017-12-12
CA2967662A1 (en) 2016-05-26
PH12017500934B1 (en) 2024-06-28
AU2021201034B2 (en) 2023-07-06
SG11201703896QA (en) 2017-06-29
KR102811263B1 (ko) 2025-05-23
US12121609B2 (en) 2024-10-22
AU2021201034A1 (en) 2021-03-11
KR20230135183A (ko) 2023-09-22
AU2015350148B2 (en) 2020-11-26
US11660267B2 (en) 2023-05-30
RS59490B1 (sr) 2019-12-31
CN107249567B (zh) 2021-08-03
EP3616686B1 (en) 2021-05-19
EP3616686A1 (en) 2020-03-04
EP3220891A1 (en) 2017-09-27

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