MX368838B - Administracion sublingual de riluzol. - Google Patents

Administracion sublingual de riluzol.

Info

Publication number
MX368838B
MX368838B MX2017006446A MX2017006446A MX368838B MX 368838 B MX368838 B MX 368838B MX 2017006446 A MX2017006446 A MX 2017006446A MX 2017006446 A MX2017006446 A MX 2017006446A MX 368838 B MX368838 B MX 368838B
Authority
MX
Mexico
Prior art keywords
riluzole
sublingual formulation
sublingual
disclosed
formulation
Prior art date
Application number
MX2017006446A
Other languages
English (en)
Spanish (es)
Other versions
MX2017006446A (es
Inventor
Yu Danny
Coric Vladimir
Samuel Vladyka Ronald
Saleh Amgad
Berman Robert
Original Assignee
Biohaven Pharm Holding Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohaven Pharm Holding Co Ltd filed Critical Biohaven Pharm Holding Co Ltd
Publication of MX2017006446A publication Critical patent/MX2017006446A/es
Publication of MX368838B publication Critical patent/MX368838B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2017006446A 2014-11-21 2015-11-17 Administracion sublingual de riluzol. MX368838B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462083094P 2014-11-21 2014-11-21
PCT/US2015/061114 WO2016081472A1 (en) 2014-11-21 2015-11-17 Sublingual formulation of riluzole

Publications (2)

Publication Number Publication Date
MX2017006446A MX2017006446A (es) 2018-02-12
MX368838B true MX368838B (es) 2019-10-18

Family

ID=55085882

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017006446A MX368838B (es) 2014-11-21 2015-11-17 Administracion sublingual de riluzol.

Country Status (24)

Country Link
US (3) US11660267B2 (enExample)
EP (3) EP3616686B8 (enExample)
JP (3) JP6753860B2 (enExample)
KR (2) KR102580378B1 (enExample)
CN (1) CN107249567B (enExample)
AU (2) AU2015350148B2 (enExample)
BR (1) BR112017010423B1 (enExample)
CA (1) CA2967662A1 (enExample)
CY (1) CY1122469T1 (enExample)
DK (1) DK3220891T3 (enExample)
EA (1) EA038518B1 (enExample)
ES (2) ES2751300T3 (enExample)
HR (1) HRP20191892T8 (enExample)
HU (1) HUE046869T2 (enExample)
IL (2) IL278188B2 (enExample)
LT (1) LT3220891T (enExample)
MX (1) MX368838B (enExample)
PH (1) PH12017500934B1 (enExample)
PL (1) PL3220891T3 (enExample)
PT (1) PT3220891T (enExample)
RS (1) RS59490B1 (enExample)
SG (1) SG11201703896QA (enExample)
SI (1) SI3220891T1 (enExample)
WO (1) WO2016081472A1 (enExample)

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AU2017341723B2 (en) 2016-10-11 2021-12-16 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of androgen receptor
JP7354123B2 (ja) * 2018-02-21 2023-10-02 エイアイ・セラピューティクス・インコーポレーテッド アピリモドとグルタミン酸作動薬を用いた併用療法
KR20210024475A (ko) * 2018-05-27 2021-03-05 바이오하벤 파마슈티컬 홀딩 컴퍼니 엘티디. 질환 치료를 위한 릴루졸 경구 붕해 정제의 용도
EA202190544A1 (ru) * 2018-08-16 2021-06-18 Биохэйвен Терапьютикс Лтд. Применение распадающихся в полости рта таблеток рилузола для лечения заболеваний
CA3158411A1 (en) * 2019-10-22 2021-04-29 Arvinas Operations, Inc. Methods of treating prostate cancer
PE20231204A1 (es) 2020-05-09 2023-08-17 Arvinas Operations Inc Metodos para fabricar un compuesto bifuncional, formas ultrapuras del compuesto bifuncional y formas de dosificacion que comprenden el mismo
US20240016783A1 (en) * 2020-10-05 2024-01-18 Icahn School Of Medicine At Mount Sinai Riluzole for the treatment of alzheimer's disease
US20240000808A1 (en) 2020-11-16 2024-01-04 Orcosa Inc. Improved use of cannabinoids in the treatment of alzheimer's disease
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
CN113876735B (zh) * 2021-10-20 2023-05-12 陇南市第一人民医院 一种利鲁唑微球制剂及其制备方法
KR102625977B1 (ko) 2021-11-24 2024-01-17 부산대학교 산학협력단 리루졸을 유효성분으로 포함하는 염증성 장질환 예방 또는 치료용 조성물
WO2025122895A1 (en) 2023-12-08 2025-06-12 Arvinas Operations, Inc. Use of androgen receptor degrader for the treatment of spinal and bulbar muscular atrophy

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Also Published As

Publication number Publication date
US11660267B2 (en) 2023-05-30
MX2017006446A (es) 2018-02-12
ES2882783T3 (es) 2021-12-02
CY1122469T1 (el) 2021-01-27
DK3220891T3 (da) 2019-11-04
EP4039247C0 (en) 2025-11-05
SG11201703896QA (en) 2017-06-29
PL3220891T3 (pl) 2020-08-24
HRP20191892T1 (hr) 2020-01-10
PT3220891T (pt) 2019-10-31
EP4039247A3 (en) 2022-11-16
EP3616686B1 (en) 2021-05-19
KR20170137032A (ko) 2017-12-12
AU2021201034A1 (en) 2021-03-11
US20210038499A1 (en) 2021-02-11
US12121609B2 (en) 2024-10-22
US20180153794A1 (en) 2018-06-07
EP3616686A1 (en) 2020-03-04
PH12017500934B1 (en) 2024-06-28
AU2015350148A1 (en) 2017-06-15
HUE046869T2 (hu) 2020-04-28
US20250114301A1 (en) 2025-04-10
HRP20191892T8 (hr) 2020-09-18
PH12017500934A1 (en) 2017-11-20
CN107249567B (zh) 2021-08-03
KR102580378B1 (ko) 2023-09-19
WO2016081472A1 (en) 2016-05-26
CA2967662A1 (en) 2016-05-26
IL278188B1 (en) 2024-11-01
IL278188B2 (en) 2025-03-01
EP4039247A2 (en) 2022-08-10
EP3220891B1 (en) 2019-07-24
EA038518B1 (ru) 2021-09-09
BR112017010423A2 (pt) 2017-12-26
LT3220891T (lt) 2019-11-11
EP3220891A1 (en) 2017-09-27
JP2017535613A (ja) 2017-11-30
JP2021001173A (ja) 2021-01-07
CN107249567A (zh) 2017-10-13
SI3220891T1 (sl) 2020-02-28
KR20230135183A (ko) 2023-09-22
AU2015350148B2 (en) 2020-11-26
JP2023065398A (ja) 2023-05-12
BR112017010423B1 (pt) 2023-09-26
EP4039247B1 (en) 2025-11-05
KR102811263B1 (ko) 2025-05-23
IL278188A (en) 2020-11-30
EP3616686B8 (en) 2021-06-23
EA201790958A1 (ru) 2018-01-31
IL252285B (en) 2020-10-29
AU2021201034B2 (en) 2023-07-06
JP6753860B2 (ja) 2020-09-09
RS59490B1 (sr) 2019-12-31
ES2751300T3 (es) 2020-03-31
IL252285A0 (en) 2017-07-31

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