HRP20191520T1 - Novi solvatirani kristalni oblik rifaksimina, proizvodnja, pripravci i njihova upotreba - Google Patents

Novi solvatirani kristalni oblik rifaksimina, proizvodnja, pripravci i njihova upotreba Download PDF

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Publication number
HRP20191520T1
HRP20191520T1 HRP20191520T HRP20191520T1 HR P20191520 T1 HRP20191520 T1 HR P20191520T1 HR P20191520 T HRP20191520 T HR P20191520T HR P20191520 T1 HRP20191520 T1 HR P20191520T1
Authority
HR
Croatia
Prior art keywords
rifaximin
crystalline form
accordance
ranging
pharmaceutical preparation
Prior art date
Application number
Other languages
English (en)
Croatian (hr)
Inventor
Giuseppe Claudio Viscomi
Paola Maffei
Annalisa Sforzini
Fabrizia Grepioni
Laura Chelazzi
Original Assignee
Alfasigma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfasigma Spa filed Critical Alfasigma Spa
Publication of HRP20191520T1 publication Critical patent/HRP20191520T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
HRP20191520 2014-05-12 2015-05-07 Novi solvatirani kristalni oblik rifaksimina, proizvodnja, pripravci i njihova upotreba HRP20191520T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461992017P 2014-05-12 2014-05-12
PCT/IB2015/053342 WO2015173697A1 (en) 2014-05-12 2015-05-07 New solvated crystal form of rifaximin, production, compositions and uses thereof
EP15726344.3A EP3143027B1 (en) 2014-05-12 2015-05-07 New solvated crystal form of rifaximin, production, compositions and uses thereof

Publications (1)

Publication Number Publication Date
HRP20191520T1 true HRP20191520T1 (hr) 2019-11-29

Family

ID=53276210

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20191520 HRP20191520T1 (hr) 2014-05-12 2015-05-07 Novi solvatirani kristalni oblik rifaksimina, proizvodnja, pripravci i njihova upotreba
HRP20201093TT HRP20201093T1 (hr) 2014-05-12 2020-07-13 Priprava i upotreba kristalnog oblika rifaksimina tau solvatiranog s degme-om

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20201093TT HRP20201093T1 (hr) 2014-05-12 2020-07-13 Priprava i upotreba kristalnog oblika rifaksimina tau solvatiranog s degme-om

Country Status (17)

Country Link
US (2) US9938298B2 (https=)
EP (2) EP3143027B1 (https=)
JP (1) JP6576953B2 (https=)
KR (1) KR102362719B1 (https=)
AU (1) AU2015260837B2 (https=)
CA (1) CA2940601C (https=)
DK (2) DK3143027T3 (https=)
EA (1) EA030457B1 (https=)
ES (2) ES2742106T3 (https=)
HR (2) HRP20191520T1 (https=)
HU (2) HUE044748T2 (https=)
NZ (1) NZ723571A (https=)
PL (2) PL3143027T3 (https=)
PT (2) PT3546464T (https=)
RS (2) RS59250B1 (https=)
SI (2) SI3546464T1 (https=)
WO (1) WO2015173697A1 (https=)

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JP7811085B2 (ja) 2017-09-01 2026-02-04 ピーティーシー セラピューティクス エムピー，インコーポレイテッド セピアプテリンを含む医薬組成物及びその使用
KR102928844B1 (ko) 2018-09-06 2026-02-19 파흐호흐슐레 노르트베스치바이츠 약물 방출 제어형 제형
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Publication number Publication date
NZ723571A (en) 2020-02-28
PT3143027T (pt) 2019-09-20
AU2015260837A1 (en) 2016-09-15
SI3546464T1 (sl) 2020-09-30
DK3143027T3 (da) 2019-08-12
ES2810010T3 (es) 2021-03-08
PT3546464T (pt) 2020-08-05
US20170088557A1 (en) 2017-03-30
KR102362719B1 (ko) 2022-02-14
PL3546464T3 (pl) 2020-11-02
DK3546464T3 (da) 2020-07-27
HRP20201093T1 (hr) 2020-10-30
SI3143027T1 (sl) 2019-10-30
US9938298B2 (en) 2018-04-10
JP2017515821A (ja) 2017-06-15
WO2015173697A1 (en) 2015-11-19
CA2940601A1 (en) 2015-11-19
EP3143027A1 (en) 2017-03-22
EA201692110A1 (ru) 2017-05-31
EP3546464B1 (en) 2020-06-17
ES2742106T3 (es) 2020-02-13
EP3546464A1 (en) 2019-10-02
HUE050054T2 (hu) 2020-11-30
EA030457B1 (ru) 2018-08-31
JP6576953B2 (ja) 2019-09-18
US20180354971A1 (en) 2018-12-13
RS59250B1 (sr) 2019-10-31
EP3143027B1 (en) 2019-07-10
US10428086B2 (en) 2019-10-01
AU2015260837B2 (en) 2019-02-28
HUE044748T2 (hu) 2019-11-28
CA2940601C (en) 2021-08-24
RS60576B1 (sr) 2020-08-31
KR20170003568A (ko) 2017-01-09
PL3143027T3 (pl) 2019-11-29

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