HRP20191416T1 - Oksidativna fotoaktivirana kompozicija za pomlađivanje kože - Google Patents

Oksidativna fotoaktivirana kompozicija za pomlađivanje kože Download PDF

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Publication number
HRP20191416T1
HRP20191416T1 HRP20191416T HRP20191416T1 HR P20191416 T1 HRP20191416 T1 HR P20191416T1 HR P20191416 T HRP20191416 T HR P20191416T HR P20191416 T1 HRP20191416 T1 HR P20191416T1
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HR
Croatia
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composition
nevus
use according
red
acid
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English (en)
Inventor
Remigio Piergallini
Nikolaos Loupis
Francesco Bellini
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Fb Dermatology Ltd
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Publication of HRP20191416T1 publication Critical patent/HRP20191416T1/hr

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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61N2005/0663—Coloured light

Claims (10)

1. Kompozicija koja sadrži najmanje jedan oksidans, najmanje jedan fotoaktivator sposoban za aktiviranje oksidansa, i najmanje jedan ljekoviti faktor za primjenu u tretmanu stanja kože pomoću metode koja obuhvaća: (a) topikalno primjenjivanje kompozicije na stanje kože pacijenta; i (b) tretiranje navedenog stanja kože aktiničnom svjetlošću tijekom vremena koje je dovoljno da navedeni fotoaktivator izazove aktivaciju navedenog oksidansa, gdje stanje kože je odabrano od akni, ožiljaka od akni, rozacee, nevusa odabranog od Beker-ovog nevusa, plavog nevusa, kongenitalnog nevusa, pigmentnog nevusa, Ota nevusa i Ito nevusa, pigmentnog nevusa vretenastih stanica, i displastičnog nevusa; i krvožilne lezije odabrane od mrežaste telangiektazije, lentigines-a, angioma nalik trešnji (cherry angioma), paukolikih angioma, krvožilnih biljega od rođenja, plave „port wine„ mrlje (blue port wine stain), crvene „port wine“ mrlje (red port wine stain), ljubičaste „port wine“ mrlje (purple port wine stain), crvene vene lica, plave vene lica, crvene vene noge, i plavih vena noge; gdje najmanje jedan oksidans je peroksid; gdje najmanje jedan fotoaktivator sadrži ksanten boju; i gdje najmanje jedan ljekoviti faktor je odabran od hijaluronske kiseline, glukozamina i alantoina.
2. Kompozicija za primjenu prema patentnom zahtjevu 1, gdje peroksid je odabran iz grupe koja se sastoji od vodik peroksida pri 3.5% do 6% ukupne kompozicije, karbamid peroksida pri 10% do 16% ukupne kompozicije, i benzoil peroksida pri 2.5% do 5% ukupne kompozicije
3. Kompozicija za primjenu prema patentnom zahtjevu 1 ili 2, koja dalje sadrži najmanje jedan hidrofilni agens za geliranje odabran od glukoze, modificiranog škroba, metil celuloze, karboksimetil celuloze, propil celuloze, hidroksipropil celuloze, karbopol (RTM) polimera, alginske kiseline, natrij alginata, kalij alginata, amonij alginata, kalcij alginata, agara, karagenana, karuba gume, pektina, i želatina.
4. Kompozicija za primjenu prema bilo kojem od patentnih zahtjeva 1 do 3, gdje fotoaktivator dalje sadrži najmanje jednu boju izvedenu iz ksantena, azo boju, biološku boju, ili karotenoid.
5. Kompozicija za primjenu prema bilo kojem od patentnih zahtjeva 1 do 4, gdje fotoaktivator dalje sadrži floksin B, eozin B, bengal roze, fluorescein, eritrozin B, rodamin B, rodamin G, rodamin WT, smjesu praha crvenog šafrana, anato ekstrakt, i ekstrakt smeđe alge, šafranin O, bazni fuksin, kiseli fuksin, 3,3'-diheksilokarbocijanin jodid, karminsku kiselinu, indocijanin zelenu, krocetin, α-krocin (8,8-diapo-8,8-karotenska kiselina), zeaksantin, likopen, α-karoten, β-karoten, biksin, fukoksantin, metil ljubičastu, neutralno crvenu, krv crvenu, amarant, karmoizin, alura crvenu AC, tartrazin, narančastu G, ponso 4R, metil crvenu, mureksid-amonij purpurat, pironin Y i pironin B.
6. Kompozicija za primjenu prema bilo kojem od patentnih zahtjeva 1 do 5, gdje kompozicija dalje sadrži najmanje jedan helatni agens odabran od etilen diamintetraoctene kiseline (EDTA) i etilen glikol tetraoctene kiseline (EGTA).
7. Kompozicija za primjenu prema bilo kojem od patentnih zahtjeva 1 do 6, gdje kompozicija dalje sadrži najmanje jedan faktor stimulacije lipolize odabran od kafeina i paraksantina.
8. Kompozicija za primjenu prema patentnim zahtjevima 1 do 7, gdje je navedeno vrijeme tretmana oko 60 sekundi do oko 5 minuta.
9. Kompozicija za primjenu prema patentnom zahtjevu 8, gdje je navedeno vrijeme tretmana oko 60 sekundi do oko 5 minuta po cm2 područja koja treba tretirati.
10. Kompozicija za primjenu prema patentnom zahtjevu 9, gdje navedena aktinična svjetlost je vidljiva svjetlost koja ima valnu dužinu između oko 400 nm i oko 600 nm.
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