HRP20191358T1 - Pripravci za oblikovanje opne za meke kapsule i meke kapsule - Google Patents
Pripravci za oblikovanje opne za meke kapsule i meke kapsule Download PDFInfo
- Publication number
- HRP20191358T1 HRP20191358T1 HRP20191358T HRP20191358T1 HR P20191358 T1 HRP20191358 T1 HR P20191358T1 HR P20191358 T HRP20191358 T HR P20191358T HR P20191358 T1 HRP20191358 T1 HR P20191358T1
- Authority
- HR
- Croatia
- Prior art keywords
- gum
- preparation according
- starch
- carrageenan
- phospholipid
- Prior art date
Links
- 239000007901 soft capsule Substances 0.000 title claims 4
- 239000000203 mixture Substances 0.000 title 1
- 229920002148 Gellan gum Polymers 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 4
- 235000010492 gellan gum Nutrition 0.000 claims 4
- 239000000216 gellan gum Substances 0.000 claims 4
- 150000003904 phospholipids Chemical class 0.000 claims 4
- 229920001353 Dextrin Polymers 0.000 claims 3
- 239000004375 Dextrin Substances 0.000 claims 3
- 229920002472 Starch Polymers 0.000 claims 3
- 239000000679 carrageenan Substances 0.000 claims 3
- 229920001525 carrageenan Polymers 0.000 claims 3
- 229940113118 carrageenan Drugs 0.000 claims 3
- 235000019425 dextrin Nutrition 0.000 claims 3
- 239000012528 membrane Substances 0.000 claims 3
- 235000019698 starch Nutrition 0.000 claims 3
- 239000008107 starch Substances 0.000 claims 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 2
- 229920000161 Locust bean gum Polymers 0.000 claims 2
- 239000006172 buffering agent Substances 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- 239000001341 hydroxy propyl starch Substances 0.000 claims 2
- 235000013828 hydroxypropyl starch Nutrition 0.000 claims 2
- 235000010420 locust bean gum Nutrition 0.000 claims 2
- 239000000711 locust bean gum Substances 0.000 claims 2
- 239000000600 sorbitol Substances 0.000 claims 2
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 244000215068 Acacia senegal Species 0.000 claims 1
- 229920001817 Agar Polymers 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- 229920002581 Glucomannan Polymers 0.000 claims 1
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920000084 Gum arabic Polymers 0.000 claims 1
- 229920002752 Konjac Polymers 0.000 claims 1
- 239000004368 Modified starch Substances 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- 239000004373 Pullulan Substances 0.000 claims 1
- 229920001218 Pullulan Polymers 0.000 claims 1
- 235000004298 Tamarindus indica Nutrition 0.000 claims 1
- 240000004584 Tamarindus indica Species 0.000 claims 1
- ZNOZWUKQPJXOIG-XSBHQQIPSA-L [(2r,3s,4r,5r,6s)-6-[[(1r,3s,4r,5r,8s)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-4-[[(1r,3r,4r,5r,8s)-8-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl]oxy]-5-hydroxy-2-( Chemical compound O[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H]2OC[C@H]1O[C@H](O[C@H]1[C@H]([C@@H](CO)O[C@@H](O[C@@H]3[C@@H]4OC[C@H]3O[C@H](O)[C@@H]4O)[C@@H]1O)OS([O-])(=O)=O)[C@@H]2O ZNOZWUKQPJXOIG-XSBHQQIPSA-L 0.000 claims 1
- 235000010489 acacia gum Nutrition 0.000 claims 1
- 239000000205 acacia gum Substances 0.000 claims 1
- 239000008272 agar Substances 0.000 claims 1
- 235000010419 agar Nutrition 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 159000000007 calcium salts Chemical class 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 235000010980 cellulose Nutrition 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- -1 furcellaran Substances 0.000 claims 1
- 229940046240 glucomannan Drugs 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 239000000252 konjac Substances 0.000 claims 1
- 235000019823 konjac gum Nutrition 0.000 claims 1
- 235000019426 modified starch Nutrition 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 1
- 235000019423 pullulan Nutrition 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 235000010491 tara gum Nutrition 0.000 claims 1
- 239000000213 tara gum Substances 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Grain Derivatives (AREA)
- General Preparation And Processing Of Foods (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Claims (8)
1. Pripravak za oblikovanje opne za meku kapsulu pogodna za kapsuliranje jezgre s uljem koje sadrži fosfolipid s koncentracijom fosfolipida od 20% ili veće mase, sadrži:
(A) škrob i/ili dekstrin;
(B) želatinizator odabran iz skupine koja se sastoji od jota-karagena, kapa-karagena, lambda-karagenana, agar, arapsku gumu, gelan gumu, prirodnu gelansku gumu, pululan, pektin, glukoman, gumu rogača, guar gumu, celulozu, konjac gumu, furcelaran, tara gumu, alginat i tamarind gumu;
(C) glicerin; i
(D) sorbitol;
pri čemu se omjer mase (C) glicerin:(D) sorbitol kreće od 100:40 do 100:70.
2. Pripravak sukladno patentnom zahtjevu 1, pri čemu navedena komponenta (A) škrob i/ili dekstrin sadrži jedan ili dva ili više tipova škroba odabran iz skupine koja sadrži kukuruzni škrob, hidroksipropil škrob, kiselinom tretiran škrob i dekstrin.
3. Pripravak sukladno patentnom zahtjevu 2, pri čemu navedena komponenta (A) sadrži hidroksipropil škrob.
4. Pripravak sukladno bilo kojem patentnom zahtjevu 1-3, pri čemu navedena komponenta (B) sadrži jedan ili više tipova komponenata odabranih iz skupine koja sadrži karagenan, karuba gumu, prirodnu gelan gumu i deacilisanu gelan gumu.
5. Pripravak sukladno bilo kojem patentnom zahtjevu 1-4, koja osim toga sadrži (E) pufersko sredstvo.
6. Pripravak sukladno patentnom zahtjevu 5, pri čemu je navedeno pufersko sredstvo (E) natrijeva sol, kalijeva sol, ili kalcijeva sol.
7. Pripravak sukladno bilo kojem patentnom zahtjevu 1-4, pri čemu navedeni pripravak ne sadrži pufersko sredstvo.
8. Meka kapsula koja sadrži:
opnu oblikovanu uz pomoću pripravka sukladno bilo kojem od patentnih zahtjeva 1-7; i jezgru kapsule s uljem koje sadrži fosfolipid s koncentracijom fosfolipida od 20% ili više s masenom koje se nalazi unutar navedene opne.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013132728A JP5769760B2 (ja) | 2013-06-25 | 2013-06-25 | ソフトカプセル用シェル形成組成物及びソフトカプセル |
| EP14816696.0A EP3013326B1 (en) | 2013-06-25 | 2014-06-24 | Shell-forming compositions for soft capsules and soft capsules |
| PCT/US2014/043814 WO2014209964A1 (en) | 2013-06-25 | 2014-06-24 | Shell-forming compositions for soft capsules and soft capsules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20191358T1 true HRP20191358T1 (hr) | 2019-11-01 |
Family
ID=52142606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20191358 HRP20191358T1 (hr) | 2013-06-25 | 2019-07-29 | Pripravci za oblikovanje opne za meke kapsule i meke kapsule |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9814683B2 (hr) |
| EP (1) | EP3013326B1 (hr) |
| JP (1) | JP5769760B2 (hr) |
| CN (1) | CN105338971B (hr) |
| AU (1) | AU2014302696B2 (hr) |
| BR (1) | BR112015032276B1 (hr) |
| CY (1) | CY1121942T1 (hr) |
| DK (1) | DK3013326T3 (hr) |
| ES (1) | ES2738882T3 (hr) |
| HR (1) | HRP20191358T1 (hr) |
| HU (1) | HUE044618T2 (hr) |
| LT (1) | LT3013326T (hr) |
| PL (1) | PL3013326T3 (hr) |
| PT (1) | PT3013326T (hr) |
| RS (1) | RS59222B1 (hr) |
| SI (1) | SI3013326T1 (hr) |
| TR (1) | TR201911096T4 (hr) |
| WO (1) | WO2014209964A1 (hr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5977470B1 (ja) * | 2015-08-05 | 2016-08-24 | 富士カプセル株式会社 | 軟カプセル皮膜用組成物 |
| CN106108086B (zh) * | 2016-06-20 | 2018-08-31 | 威海百合生物技术股份有限公司 | 一种磷脂软胶囊 |
| CN106214660A (zh) * | 2016-08-16 | 2016-12-14 | 国家海洋局第海洋研究所 | 可制成植物软胶囊囊材的组合物及植物软胶囊 |
| JP2018121699A (ja) * | 2017-01-30 | 2018-08-09 | 株式会社アクレス | クリルオイルを充填したカプセル剤 |
| CN107375229A (zh) * | 2017-06-26 | 2017-11-24 | 仙乐健康科技股份有限公司 | 一种咀嚼植物软胶囊及其制备方法 |
| US10711119B2 (en) | 2018-01-10 | 2020-07-14 | Cp Kelco Aps | Carrageenan-based compositions for films and capsules |
| CN110478312A (zh) * | 2019-08-29 | 2019-11-22 | 仙乐健康科技股份有限公司 | 具有高油脂含量的稳定凝胶组合物及其制备方法和用途 |
| CN112210103A (zh) * | 2020-11-03 | 2021-01-12 | 赵书敏 | 一种食品包装膜及其制备方法 |
| CN113180136A (zh) * | 2021-04-13 | 2021-07-30 | 浙江新维士生物科技有限公司 | 一种凝胶软糖的制备方法 |
| AU2021107198A4 (en) * | 2021-08-24 | 2021-12-09 | Blackmores Ltd | A softgel capsule composition, and a process for producing a softgel capsule therefrom |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6340473B1 (en) * | 1999-07-07 | 2002-01-22 | R.P. Scherer Technologies, Inc. | Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same |
| US6375981B1 (en) * | 2000-06-01 | 2002-04-23 | A. E. Staley Manufacturing Co. | Modified starch as a replacement for gelatin in soft gel films and capsules |
| US6949256B2 (en) * | 2002-01-18 | 2005-09-27 | Banner Pharmacaps, Inc. | Non-gelatin capsule shell formulation |
| US7887838B2 (en) * | 2002-01-18 | 2011-02-15 | Banner Pharmacaps, Inc. | Non-gelatin film and method and apparatus for producing same |
| US20050019295A1 (en) * | 2003-04-14 | 2005-01-27 | Fmc Corporation | Homogeneous, thermoreversible low viscosity polymannan gum films and soft capsules made therefrom |
| EP1621211A1 (en) * | 2003-05-02 | 2006-02-01 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Soft capsule film and soft capsule |
| JP4242266B2 (ja) | 2003-12-19 | 2009-03-25 | 三生医薬株式会社 | カプセル剤皮組成物 |
| AU2005206084A1 (en) * | 2004-01-09 | 2005-08-04 | Wyeth | Microemulsions for pharmaceutical compositions |
| US8231896B2 (en) | 2004-11-08 | 2012-07-31 | R.P. Scherer Technologies, Llc | Non-gelatin soft capsule system |
| US8574624B2 (en) * | 2006-11-17 | 2013-11-05 | Corn Products Development, Inc. | Highly inhibited starch fillers for films and capsules |
| JP4797211B2 (ja) * | 2009-02-05 | 2011-10-19 | キャタレント・ジャパン株式会社 | ソフトカプセル用フィルム形成組成物 |
| JP5421674B2 (ja) * | 2009-07-01 | 2014-02-19 | 株式会社ファンケル | ソフトカプセル用乳化組成物及びソフトカプセル剤 |
| US20110171281A1 (en) * | 2010-01-14 | 2011-07-14 | Karl Wei Cao | Soft capsule composition and method of use |
| KR101288079B1 (ko) * | 2010-08-04 | 2013-07-22 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 연질캡슐용 막 형성 조성물 |
| WO2012031186A1 (en) * | 2010-09-03 | 2012-03-08 | Wisconsin Pharmacal Company, Llc. | Prebiotic suppositories |
-
2013
- 2013-06-25 JP JP2013132728A patent/JP5769760B2/ja active Active
-
2014
- 2014-06-24 WO PCT/US2014/043814 patent/WO2014209964A1/en active Application Filing
- 2014-06-24 PL PL14816696T patent/PL3013326T3/pl unknown
- 2014-06-24 EP EP14816696.0A patent/EP3013326B1/en active Active
- 2014-06-24 CN CN201480036675.XA patent/CN105338971B/zh active Active
- 2014-06-24 ES ES14816696T patent/ES2738882T3/es active Active
- 2014-06-24 DK DK14816696.0T patent/DK3013326T3/da active
- 2014-06-24 BR BR112015032276-0A patent/BR112015032276B1/pt active IP Right Grant
- 2014-06-24 US US14/392,343 patent/US9814683B2/en active Active
- 2014-06-24 RS RSP20190969 patent/RS59222B1/sr unknown
- 2014-06-24 SI SI201431270T patent/SI3013326T1/sl unknown
- 2014-06-24 TR TR2019/11096T patent/TR201911096T4/tr unknown
- 2014-06-24 LT LTEP14816696.0T patent/LT3013326T/lt unknown
- 2014-06-24 AU AU2014302696A patent/AU2014302696B2/en active Active
- 2014-06-24 HU HUE14816696 patent/HUE044618T2/hu unknown
- 2014-06-24 PT PT14816696T patent/PT3013326T/pt unknown
-
2019
- 2019-07-29 HR HRP20191358 patent/HRP20191358T1/hr unknown
- 2019-07-31 CY CY20191100819T patent/CY1121942T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015032276B1 (pt) | 2023-02-07 |
| CN105338971B (zh) | 2019-08-02 |
| JP2015007008A (ja) | 2015-01-15 |
| EP3013326A4 (en) | 2016-07-06 |
| AU2014302696B2 (en) | 2019-01-31 |
| TR201911096T4 (tr) | 2019-08-21 |
| CN105338971A (zh) | 2016-02-17 |
| BR112015032276A2 (pt) | 2017-07-25 |
| EP3013326A1 (en) | 2016-05-04 |
| ES2738882T3 (es) | 2020-01-27 |
| PL3013326T3 (pl) | 2019-10-31 |
| LT3013326T (lt) | 2019-09-25 |
| AU2014302696A1 (en) | 2016-01-21 |
| HUE044618T2 (hu) | 2019-11-28 |
| RS59222B1 (sr) | 2019-10-31 |
| EP3013326B1 (en) | 2019-06-19 |
| CY1121942T1 (el) | 2020-10-14 |
| SI3013326T1 (sl) | 2019-09-30 |
| JP5769760B2 (ja) | 2015-08-26 |
| US9814683B2 (en) | 2017-11-14 |
| DK3013326T3 (da) | 2019-08-05 |
| PT3013326T (pt) | 2019-08-05 |
| US20160271069A1 (en) | 2016-09-22 |
| WO2014209964A1 (en) | 2014-12-31 |
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