HRP20161366T1 - Čvrsti pripravci za oralnu primjenu boja te njihova dijagnostička uporaba - Google Patents
Čvrsti pripravci za oralnu primjenu boja te njihova dijagnostička uporaba Download PDFInfo
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- HRP20161366T1 HRP20161366T1 HRP20161366TT HRP20161366T HRP20161366T1 HR P20161366 T1 HRP20161366 T1 HR P20161366T1 HR P20161366T T HRP20161366T T HR P20161366TT HR P20161366 T HRP20161366 T HR P20161366T HR P20161366 T1 HRP20161366 T1 HR P20161366T1
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- Croatia
- Prior art keywords
- preparation according
- mixtures
- cellulose
- dye
- compounds
- Prior art date
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- 239000000975 dye Substances 0.000 title 1
- 239000008247 solid mixture Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 10
- 239000001913 cellulose Substances 0.000 claims 4
- 229920002678 cellulose Polymers 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 229920002472 Starch Polymers 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 229940106189 ceramide Drugs 0.000 claims 2
- 150000001783 ceramides Chemical class 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 238000005755 formation reaction Methods 0.000 claims 2
- -1 glycol alkyl ethers Chemical class 0.000 claims 2
- 150000002433 hydrophilic molecules Chemical class 0.000 claims 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 150000002634 lipophilic molecules Chemical class 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- SBASXUCJHJRPEV-UHFFFAOYSA-N 2-(2-methoxyethoxy)ethanol Chemical group COCCOCCO SBASXUCJHJRPEV-UHFFFAOYSA-N 0.000 claims 1
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 claims 1
- 229920001353 Dextrin Polymers 0.000 claims 1
- 239000004375 Dextrin Substances 0.000 claims 1
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 claims 1
- 244000043261 Hevea brasiliensis Species 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- 206010056626 Pseudopolyp Diseases 0.000 claims 1
- 229920001800 Shellac Polymers 0.000 claims 1
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 claims 1
- 208000025865 Ulcer Diseases 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 239000000783 alginic acid Substances 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 229960001126 alginic acid Drugs 0.000 claims 1
- 150000004781 alginic acids Chemical class 0.000 claims 1
- 229920013820 alkyl cellulose Polymers 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000008051 alkyl sulfates Chemical class 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 125000004181 carboxyalkyl group Chemical group 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 150000001841 cholesterols Chemical class 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- IQFVPQOLBLOTPF-HKXUKFGYSA-L congo red Chemical compound [Na+].[Na+].C1=CC=CC2=C(N)C(/N=N/C3=CC=C(C=C3)C3=CC=C(C=C3)/N=N/C3=C(C4=CC=CC=C4C(=C3)S([O-])(=O)=O)N)=CC(S([O-])(=O)=O)=C21 IQFVPQOLBLOTPF-HKXUKFGYSA-L 0.000 claims 1
- 235000019425 dextrin Nutrition 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229920013821 hydroxy alkyl cellulose Polymers 0.000 claims 1
- KHLVKKOJDHCJMG-QDBORUFSSA-L indigo carmine Chemical compound [Na+].[Na+].N/1C2=CC=C(S([O-])(=O)=O)C=C2C(=O)C\1=C1/NC2=CC=C(S(=O)(=O)[O-])C=C2C1=O KHLVKKOJDHCJMG-QDBORUFSSA-L 0.000 claims 1
- 229960003988 indigo carmine Drugs 0.000 claims 1
- 235000012738 indigotine Nutrition 0.000 claims 1
- 239000004179 indigotine Substances 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- CXKWCBBOMKCUKX-UHFFFAOYSA-M methylene blue Chemical group [Cl-].C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 CXKWCBBOMKCUKX-UHFFFAOYSA-M 0.000 claims 1
- 229960000907 methylthioninium chloride Drugs 0.000 claims 1
- 235000019426 modified starch Nutrition 0.000 claims 1
- 229920003052 natural elastomer Polymers 0.000 claims 1
- 229920001194 natural rubber Polymers 0.000 claims 1
- 230000001613 neoplastic effect Effects 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 150000004804 polysaccharides Chemical class 0.000 claims 1
- 230000001855 preneoplastic effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims 1
- 239000004208 shellac Substances 0.000 claims 1
- 229940113147 shellac Drugs 0.000 claims 1
- 235000013874 shellac Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 150000005846 sugar alcohols Polymers 0.000 claims 1
- 229920003051 synthetic elastomer Polymers 0.000 claims 1
- 239000005061 synthetic rubber Substances 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/041—Capsule endoscopes for imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/273—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/31—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/003—Thiazine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0073—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form semi-solid, gel, hydrogel, ointment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0089—Particulate, powder, adsorbate, bead, sphere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/005—Devices for introducing or retaining media, e.g. remedies, in cavities of the body for contrast media
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Claims (15)
1. Čvrsti pripravak za oralnu primjenu koji sadrži barem jednu boju zajedno s barem jednom fiziološki prikladnom pomoćnom tvari, naznačen time što sadrži:
a. matriks koji se sastoji od lipofilnih spojeva s talištem nižim od 90°C, i amfifilnih spojeva, gdje je barem jedna boja barem djelomično inkorporirana;
b. vanjski matriks koji se sastoji od hidrofilnih spojeva, a u kojem su lipofilni matriks i amfifilni matriks dispergirani;
c. po izboru druge fiziološki prikladne pomoćne tvari;
d. po izboru želučanootpornu ovojnicu,
gdje se ta barem jedna boja odabire između metilenskog modrila, kongo crvene, indigo karmin, toluenskog modrila ili njihovih smjesa i prisutna je u količini u rasponu između 10 mg i 1500 mg.
2. Pripravak prema prethodnim zahtjevima, gdje je ta barem jedna boja prisutna u količini u rasponu između 50 mg i 1200 mg.
3. Pripravak prema prethodnim zahtjevima, gdje je ta barem jedna boja prisutna u količini u rasponu između 20 mg i 500 mg.
4. Pripravak prema prethodnim zahtjevima, gdje je ta barem jedna boja prisutna u količini ekvivalentnoj 25 mg.
5. Pripravak prema prethodnim zahtjevima, gdje je ta barem jedna boja prisutna u količini ekvivalentnoj 50 mg.
6. Pripravak prema prethodnim zahtjevima, u obliku tablete ili kapsule.
7. Pripravak prema prethodnim zahtjevima, gdje se lipofilni spojevi odabiru između zasićenih, nezasićenih ili hidrogeniranih dugolančanih alkohola, zasićenih, nezasićenih ili hidrogeniranih masnih kiselina, njihovih soli, estera ili amida, mono-, di- ili triglicerida masnih kiselina, njihovih polietoksiliranih derivata, voskova, ceramida, kolesterola, derivata kolesterola ili njihovih mješavina.
8. Pripravak prema prethodnim zahtjevima, gdje se amfifilni spojevi odabiru između polarnih lipida tipa I ili II, ceramida, glikol alkil etera, alkil sulfatnih ili sulfosukcinatnih soli ili njihovih mješavina.
9. Pripravak prema prethodnim zahtjevima, gdje se navedeni polarni lipidi tipa I ili II odabiru između lecitina, fosfatidilkolina, fosfatidiletanolamina ili njihovih mješavina, i navedeni glikol alkil eter je dietilen glikol monometil eter.
10. Pripravak prema prethodnim zahtjevima, gdje su hidrofilni spojevi oni spojevi koji formiraju hidrogel, poželjno odabrani između polimera ili kopolimera akrilatne ili metakrilatne kiseline, alkil vinil polimera, alkil celuloza, hidroksialkil celuloza, karboksialkil celuloza, modificiranih celuloza, plurisupstituiranih celuloza, polisaharida, dekstrina, pektina, škrobova, kompleksnih škrobova, derivata škroba, alginatne kiseline, sintetičke gume, prirodne gume, poliakohola ili njihovih mješavina.
11. Pripravak prema prethodnim zahtjevima, gdje se želučanootporna ovojnica odabire između polimera akrilatne ili metakrilatne kiseline, kopolimera akrilatne ili metakrilatne kiseline, derivata celuloze, polimera na bazi hidroksibutirata, šelaka ili njihovih mješavina.
12. Pripravak prema bilo kojem od prethodnim zahtjevima za dijagnostičku svrhu.
13. Pripravak prema zahtjevu 12 za uporabu u endoskopskoj dijagnostičkoj procjeni probavnog trakta.
14. Pripravak prema zahtjevu 12 za uporabu u endoskopskoj dijagnostičkoj procjeni upalnih, ulceroznih, displastičnih, pre-neoplastičnih i neoplastičnih patologija probavnog trakta.
15. Pripravak prema zahtjevu 12 za uporabu u endoskopskoj dijagnostičkoj procjeni kanceroznih tvorbi, prekanceroznih tvorbi, polipa, pseudopolipa ili različitih upalnih patologija probavnog trakta.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A000345A IT1398643B1 (it) | 2010-03-04 | 2010-03-04 | Composizione solida per la somministrazione orale di coloranti, e utilizzo diagnostico della stessa |
| US32755710P | 2010-04-23 | 2010-04-23 | |
| EP11714409.7A EP2542268B1 (en) | 2010-03-04 | 2011-03-02 | Solid composition for the oral administration of dyes and diagnostic use thereof |
| PCT/IB2011/050881 WO2011107945A1 (en) | 2010-03-04 | 2011-03-02 | Solid composition for the oral administration of dyes and diagnostic use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161366T1 true HRP20161366T1 (hr) | 2017-02-24 |
Family
ID=42647312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161366TT HRP20161366T1 (hr) | 2010-03-04 | 2016-10-19 | Čvrsti pripravci za oralnu primjenu boja te njihova dijagnostička uporaba |
| HRP20210493TT HRP20210493T1 (hr) | 2010-03-04 | 2021-03-26 | Čvrsti pripravak za oralnu primjenu boja te njegova dijagnostička uporaba |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20210493TT HRP20210493T1 (hr) | 2010-03-04 | 2021-03-26 | Čvrsti pripravak za oralnu primjenu boja te njegova dijagnostička uporaba |
Country Status (26)
| Country | Link |
|---|---|
| US (6) | US8545811B2 (hr) |
| EP (2) | EP2542268B1 (hr) |
| JP (1) | JP5770752B2 (hr) |
| KR (1) | KR101763700B1 (hr) |
| CN (1) | CN102811747B (hr) |
| AU (1) | AU2011222496B2 (hr) |
| BR (1) | BR112012022373B1 (hr) |
| CA (1) | CA2790143C (hr) |
| CY (1) | CY1123967T1 (hr) |
| DK (2) | DK3011975T3 (hr) |
| ES (2) | ES2863986T3 (hr) |
| FR (1) | FR21C1009I1 (hr) |
| HR (2) | HRP20161366T1 (hr) |
| HU (3) | HUE053977T2 (hr) |
| IL (1) | IL221541A (hr) |
| IT (1) | IT1398643B1 (hr) |
| LT (2) | LT3011975T (hr) |
| MX (1) | MX342323B (hr) |
| NZ (1) | NZ602130A (hr) |
| PL (2) | PL3011975T3 (hr) |
| PT (2) | PT2542268T (hr) |
| RS (2) | RS61641B1 (hr) |
| RU (1) | RU2561034C2 (hr) |
| SI (1) | SI3011975T1 (hr) |
| WO (1) | WO2011107945A1 (hr) |
| ZA (1) | ZA201206360B (hr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| EP2722058A1 (en) * | 2012-10-19 | 2014-04-23 | Cosmo Technologies Ltd | Solid oral composition containing dyes for use in endoscopic diagnosis |
| CA2936792C (en) * | 2014-01-29 | 2022-03-29 | Cosmo Technologies Limited | Liquid composition in the form of emulsion or microemulsion for rectal administration containing at least one dye, and its use in a diagnostic endoscopic procedure of sigmoid colon and/or rectum |
| US10124074B2 (en) * | 2014-02-26 | 2018-11-13 | Toufic Kachaamy | Indirect chromoendoscopy with an oral indigo carmine base preparation |
| CN106999618A (zh) | 2014-12-08 | 2017-08-01 | 金诺斯公司 | 用于颜料消毒的添加剂组合物及其方法 |
| WO2016171763A1 (en) * | 2015-04-23 | 2016-10-27 | Obalon Therapeutics, Inc. | Systems and methods for determining failure of intragastric devices |
| US10344251B2 (en) | 2016-02-12 | 2019-07-09 | Kinnos, Inc. | Compositions and methods for use in surface decontamination |
| EA201892365A1 (ru) | 2016-04-19 | 2019-03-29 | Конарис Рисерч Инститьют Аг | Составы и композиции шеллачных микрокапсул |
| CN109715777B (zh) | 2016-07-25 | 2022-04-19 | 金诺斯公司 | 用于表面净化的装置和相关组合物及方法 |
| CA3043451A1 (en) | 2016-11-28 | 2018-05-31 | Cosmo Technologies Ltd. | Solid oral composition containing dyes |
| FR3059664B1 (fr) | 2016-12-01 | 2019-01-25 | Provepharm Life Solutions | Procede de preparation du carmin d’indigo |
| CA3104884A1 (en) | 2018-07-12 | 2020-01-16 | Kinnos Inc. | Devices, compositions, and methods for use in surface decontamination |
| CN108888765B (zh) * | 2018-07-16 | 2021-02-26 | 山东理工大学 | 一种释放亚甲基蓝聚集体的含亚甲基蓝的二氧化硅/虫胶复合颗粒的制备方法 |
| CN111184876B (zh) * | 2020-02-20 | 2022-03-04 | 沈伟 | 一种消化道黏膜染色剂、制备方法及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3361632A (en) * | 1964-05-08 | 1968-01-02 | Hoechst Ag | Medicinal preparations having a protracted activity and method of making them |
| JP3549880B2 (ja) * | 1991-10-31 | 2004-08-04 | ジラ・インコーポレーテッド | 生物学的染料組成物、調製方法および上皮癌描写への使用方法 |
| US6405070B1 (en) * | 1998-06-16 | 2002-06-11 | Bhaskar Banerjee | Detection of cancer using cellular autofluorescence |
| ITMI991316A1 (it) | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
| US6584630B1 (en) | 2000-04-06 | 2003-07-01 | Ohio Medical Instrument Company, Inc. | Radiolucent surgical table extension assembly and method |
| WO2001076478A1 (en) | 2000-04-10 | 2001-10-18 | Nordisk Terapi As | System for testing and exercising sensorimotoric control of the neck |
| FR2829933B3 (fr) * | 2001-09-21 | 2004-03-12 | Ellipse Pharmaceuticals | Procede de fabrication d'un produit pharmaceutique administrable par voie orale avec des agents detrompeurs notamment de gout et produit obtenu |
| US7217410B2 (en) | 2003-06-17 | 2007-05-15 | The Board Of Trustees Of The Universtiy Of Illinois | Surface modified protein microparticles |
| US20070077202A1 (en) * | 2005-06-12 | 2007-04-05 | Pentax Corporation | Histostain composition for endoscope |
| US20070116757A1 (en) * | 2005-11-08 | 2007-05-24 | Collegium Pharmaceutical, Inc. | Methylene Blue Derivatives |
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