HRP20141099T1 - Topiäśki pripravci za saäśuvanje ili ponovno uspostavljanje cjelovitosti sluznice - Google Patents
Topiäśki pripravci za saäśuvanje ili ponovno uspostavljanje cjelovitosti sluznice Download PDFInfo
- Publication number
- HRP20141099T1 HRP20141099T1 HRP20141099AT HRP20141099T HRP20141099T1 HR P20141099 T1 HRP20141099 T1 HR P20141099T1 HR P20141099A T HRP20141099A T HR P20141099AT HR P20141099 T HRP20141099 T HR P20141099T HR P20141099 T1 HRP20141099 T1 HR P20141099T1
- Authority
- HR
- Croatia
- Prior art keywords
- topical preparations
- reported
- hyaluronic acid
- alfoscerate
- choline
- Prior art date
Links
- 230000000699 topical effect Effects 0.000 title claims 11
- 239000000203 mixture Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 claims 11
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 4
- 239000008777 Glycerylphosphorylcholine Substances 0.000 claims 4
- 229960004788 choline alfoscerate Drugs 0.000 claims 4
- SUHOQUVVVLNYQR-MRVPVSSYSA-O glycerylphosphorylcholine Chemical compound C[N+](C)(C)CCO[P@](O)(=O)OC[C@H](O)CO SUHOQUVVVLNYQR-MRVPVSSYSA-O 0.000 claims 4
- 229920002674 hyaluronan Polymers 0.000 claims 4
- 229960003160 hyaluronic acid Drugs 0.000 claims 4
- 210000004877 mucosa Anatomy 0.000 claims 4
- 210000004400 mucous membrane Anatomy 0.000 claims 3
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 claims 2
- 229960004963 mesalazine Drugs 0.000 claims 2
- 210000000214 mouth Anatomy 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 235000002961 Aloe barbadensis Nutrition 0.000 claims 1
- 244000186892 Aloe vera Species 0.000 claims 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 1
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- 235000011399 aloe vera Nutrition 0.000 claims 1
- 229960000686 benzalkonium chloride Drugs 0.000 claims 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 1
- 229960003260 chlorhexidine Drugs 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 235000011477 liquorice Nutrition 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 210000003928 nasal cavity Anatomy 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (10)
1. Topički pripravci koji sadrže kolin-alfoscerat i hialuronsku kiselinu ili njihovu farmaceutski prihvatljivu sol te najmanje jedan farmaceutski prihvatljiv ekscipijens ili nosač, za upotrebu u terapiji, naznačeni time da pripravci poboljšavaju mukoadheziju hialuronske kiseline i potiču zadržavanje kolina-alfoscerata na membranama sluznice.
2. Topički pripravci za upotrebu kako su prijavljeni u patentnom zahtjevu 1, naznačeni time da je koncentracija kolin-alfoscerat između 0.001% w/v i 99% w/v.
3. Topički pripravci za upotrebu kako su prijavljeni u patentnom zahtjevu 2, naznačeni time da je koncentracija kolin-alfoscerata između 0.010% w/v i 50% w/v.
4. Topički pripravci za upotrebu kako su prijavljeni u patentnom zahtjevu 1, naznačeni time da je hialuronska kiselina u obliku natrijeve soli.
5. Topički pripravci za upotrebu kako su prijavljeni u patentnim zahtjevima 1 ili 4, naznačeni time da hialuronska kiselina ili odgovarajuća farmaceutsko prihvatljiva sol ima molekulsku masu između 800 000 i 4 000 000 Da.
6. Topički pripravci za upotrebu kako su prijavljeni u patentnim zahtjevima 1-5, naznačeni time da sadrže najmanje jedan daljnji sastojak odabran od sljedećih: mezalazin, likvoris, srebro, aloe vera, alantonin, klorheksidin te benzalkonijev klorid.
7. Topički pripravci za upotrebu kako su prijavljeni u patentnom zahtjevu 6, naznačeni time da aktivni konstituent jest mezalazin.
8. Topički pripravci za upotrebu kako su prijavljeni u patentnim zahtjevima 1 - 7, naznačeni time da su u obliku vodenog gela.
9. Topički pripravci za upotrebu kako su prijavljeni u patentnim zahtjevima 1 - 8, naznačeni time da su za humanu i veterinarsku primjenu.
10. Topički pripravci za upotrebu kako su prijavljeni u patentnim zahtjevima 1 - 9, naznačeni time da membrane sluznice jesu vanjske membrane sluznice usta, oralne šupljine, nosne šupljine, okulama sluznica, sluzica uha, sluznica muških i ženskih genitalija te rektalna sluznica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A002218A IT1402907B1 (it) | 2010-11-30 | 2010-11-30 | Composizioni topiche per mantenere o ripristinare l'integrita' delle mucose. |
| PCT/IB2011/055364 WO2012073191A1 (en) | 2010-11-30 | 2011-11-29 | Topical compositions for preserving or restoring the integrity of mucosae |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20141099T1 true HRP20141099T1 (hr) | 2014-12-19 |
Family
ID=43742830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20141099AT HRP20141099T1 (hr) | 2010-11-30 | 2014-11-12 | Topiäśki pripravci za saäśuvanje ili ponovno uspostavljanje cjelovitosti sluznice |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US9050351B2 (hr) |
| EP (1) | EP2646036B1 (hr) |
| JP (1) | JP5847833B2 (hr) |
| KR (1) | KR101845472B1 (hr) |
| CN (1) | CN103313716B (hr) |
| AU (1) | AU2011336166B2 (hr) |
| BR (1) | BR112013013351B1 (hr) |
| CA (1) | CA2819307C (hr) |
| CY (1) | CY1115708T1 (hr) |
| DK (1) | DK2646036T3 (hr) |
| ES (1) | ES2521065T3 (hr) |
| HK (1) | HK1185008A1 (hr) |
| HR (1) | HRP20141099T1 (hr) |
| IL (1) | IL226638A (hr) |
| IT (1) | IT1402907B1 (hr) |
| MX (1) | MX337437B (hr) |
| PL (1) | PL2646036T3 (hr) |
| PT (1) | PT2646036E (hr) |
| RS (1) | RS53598B1 (hr) |
| RU (1) | RU2013125021A (hr) |
| SI (1) | SI2646036T1 (hr) |
| WO (1) | WO2012073191A1 (hr) |
| ZA (1) | ZA201303910B (hr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102940724A (zh) * | 2012-08-16 | 2013-02-27 | 江西普正制药有限公司 | 一种用于消炎的中药复方胶囊的制备方法 |
| ITMI20131219A1 (it) * | 2013-07-19 | 2015-01-20 | Ricerfarma Srl | Colina alfoscerato come inibitore di ialuronidasi |
| RU2551312C1 (ru) * | 2014-04-24 | 2015-05-20 | Людмила Владимировна Уварова | Способ восстановления тканей зубочелюстной системы |
| KR101853347B1 (ko) * | 2014-08-29 | 2018-04-30 | 주식회사유한양행 | 콜린 알포세레이트-함유 정제 및 이의 제조방법 |
| ES2827426T3 (es) * | 2015-03-26 | 2021-05-21 | Dmg Italia Srl | Composición oftálmica para la protección corneal |
| CZ28634U1 (cs) | 2015-05-05 | 2015-09-14 | Contipro Pharma A.S. | Dentální přípravek na bázi hyaluronanu a oktenidin dihydrochloridu |
| RU2632718C2 (ru) * | 2015-12-25 | 2017-10-09 | Общество с ограниченной ответственностью "Фармамед" | Спрей для орального применения, содержащий холина альфосцерат. |
| KR101744538B1 (ko) * | 2017-03-17 | 2017-06-09 | 주식회사 대웅제약 | 콜린 알포세레이트를 함유하는 수성 액상 제제 |
| IT201700048750A1 (it) * | 2017-05-05 | 2018-11-05 | Farm Procemsa S P A | Composizione per il trattamento di afte e ulcere buccali |
| RU2684118C2 (ru) * | 2017-09-27 | 2019-04-04 | Общество с ограниченной ответственностью "Фармамед" | Спрей для орального применения, содержащий холина альфосцерат |
| KR101864384B1 (ko) * | 2017-12-11 | 2018-06-04 | (주)나노스템 | 콜린 알포세레이트를 유효성분으로 하는 쥐남의 치료, 개선 또는 예방용 조성물 및 방법 |
| WO2019208898A1 (ko) * | 2018-04-24 | 2019-10-31 | 한국유나이티드제약 주식회사 | 콜린알포세레이트를 함유하는 액상 시럽제제 |
| CN108452291A (zh) * | 2018-07-04 | 2018-08-28 | 西南大学 | 用天然丝胶蛋白治疗溃疡性结肠炎的方法 |
| BR112021024266A2 (pt) | 2019-06-14 | 2022-01-11 | Procter & Gamble | Composições para tratamento bucal sem enxágue |
| EP3982913A1 (en) * | 2019-06-14 | 2022-04-20 | The Procter & Gamble Company | Leave-on oral care compositions |
| MX2021015126A (es) * | 2019-06-14 | 2022-01-24 | Procter & Gamble | Composiciones para el cuidado bucal para usar y no enjuagar. |
| IT202000004069A1 (it) * | 2020-02-27 | 2021-08-27 | Ricerfarma Srl | Composizioni topiche per il mantenimento e/o ripristino dell’integrità delle mucose e dell’epidermide lesa |
| IT202000022042A1 (it) * | 2020-09-18 | 2022-03-18 | Ricerfarma Srl | Composizioni topiche antivirali comprendenti acido ialuronico e carragenina |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1240316B (it) * | 1990-02-21 | 1993-12-07 | Ricerca Di Schiena Del Dr. Michele G. Di Schiema & C. | Composizioni a base di acido ialuronico ad alto peso molecolare somministrabili per via topica per il trattamento di infiammazioni del cavo orale ,per la cosmetica e l'igiene del cavo orale |
| CH683671A5 (it) * | 1992-03-30 | 1994-04-29 | Golgi Sa | Uso topico di glicerofosfolipidi deacilati. |
| JPH06107550A (ja) * | 1992-09-29 | 1994-04-19 | Yutaka Kurachi | 経口抗炎症剤 |
| US20020049422A1 (en) * | 1994-03-31 | 2002-04-25 | Brewitt Barbara A. | Homeopathic preparations |
| WO2000056344A1 (fr) * | 1999-03-24 | 2000-09-28 | Seikagaku Corporation | Salive artificielle |
| US7354910B2 (en) * | 2001-10-18 | 2008-04-08 | Seikagaku Kogyo Kabushiki Kaisha | Agent for treating inflammatory bowel diseases |
| WO2005054204A2 (en) * | 2003-11-26 | 2005-06-16 | Synchrony Biosciences, Inc. | Pharmaceutical compounds that regenerate in vivo |
| US20050143343A1 (en) * | 2003-12-30 | 2005-06-30 | Nerenberg Arnold P. | Nutritional supplement for enhancing the production and effect of natural human growth hormone |
| ITMI20061932A1 (it) * | 2006-10-09 | 2008-04-10 | Carlo Ghisalberti | Complessi a trasferimento di carica per uso medicale |
| JP5198899B2 (ja) * | 2008-02-28 | 2013-05-15 | 株式会社コーセー | 細胞賦活剤及び老化防止用皮膚外用剤 |
| JP2009155337A (ja) * | 2009-03-31 | 2009-07-16 | Tsujido Chemical Corp | 治療剤 |
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2010
- 2010-11-30 IT ITMI2010A002218A patent/IT1402907B1/it active
-
2011
- 2011-03-11 US US13/046,094 patent/US9050351B2/en active Active
- 2011-11-29 WO PCT/IB2011/055364 patent/WO2012073191A1/en active Application Filing
- 2011-11-29 JP JP2013541459A patent/JP5847833B2/ja active Active
- 2011-11-29 CN CN201180057305.0A patent/CN103313716B/zh active Active
- 2011-11-29 CA CA2819307A patent/CA2819307C/en active Active
- 2011-11-29 EP EP11805602.7A patent/EP2646036B1/en active Active
- 2011-11-29 SI SI201130311T patent/SI2646036T1/sl unknown
- 2011-11-29 PT PT118056027T patent/PT2646036E/pt unknown
- 2011-11-29 MX MX2013006045A patent/MX337437B/es active IP Right Grant
- 2011-11-29 KR KR1020137013797A patent/KR101845472B1/ko active IP Right Grant
- 2011-11-29 RU RU2013125021/15A patent/RU2013125021A/ru unknown
- 2011-11-29 BR BR112013013351A patent/BR112013013351B1/pt active IP Right Grant
- 2011-11-29 RS RSP20140602 patent/RS53598B1/en unknown
- 2011-11-29 AU AU2011336166A patent/AU2011336166B2/en active Active
- 2011-11-29 ES ES11805602.7T patent/ES2521065T3/es active Active
- 2011-11-29 PL PL11805602T patent/PL2646036T3/pl unknown
- 2011-11-29 DK DK11805602.7T patent/DK2646036T3/da active
-
2013
- 2013-05-29 ZA ZA2013/03910A patent/ZA201303910B/en unknown
- 2013-05-29 IL IL226638A patent/IL226638A/en active IP Right Grant
- 2013-11-05 HK HK13112418.4A patent/HK1185008A1/zh unknown
-
2014
- 2014-10-16 CY CY20141100854T patent/CY1115708T1/el unknown
- 2014-11-12 HR HRP20141099AT patent/HRP20141099T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS53598B1 (en) | 2015-02-27 |
| BR112013013351A2 (pt) | 2016-09-13 |
| PT2646036E (pt) | 2014-11-03 |
| CA2819307A1 (en) | 2012-06-07 |
| AU2011336166B2 (en) | 2016-03-24 |
| AU2011336166A1 (en) | 2013-06-20 |
| WO2012073191A1 (en) | 2012-06-07 |
| HK1185008A1 (zh) | 2014-02-07 |
| DK2646036T3 (da) | 2014-10-06 |
| JP5847833B2 (ja) | 2016-01-27 |
| KR20140020838A (ko) | 2014-02-19 |
| ITMI20102218A1 (it) | 2012-05-31 |
| US9050351B2 (en) | 2015-06-09 |
| KR101845472B1 (ko) | 2018-04-04 |
| EP2646036B1 (en) | 2014-08-27 |
| ZA201303910B (en) | 2014-07-30 |
| PL2646036T3 (pl) | 2015-02-27 |
| MX337437B (es) | 2016-03-03 |
| IT1402907B1 (it) | 2013-09-27 |
| CY1115708T1 (el) | 2017-01-25 |
| IL226638A (en) | 2016-08-31 |
| CN103313716A (zh) | 2013-09-18 |
| JP2014501733A (ja) | 2014-01-23 |
| SI2646036T1 (sl) | 2014-12-31 |
| RU2013125021A (ru) | 2014-12-10 |
| MX2013006045A (es) | 2013-10-25 |
| EP2646036A1 (en) | 2013-10-09 |
| BR112013013351B1 (pt) | 2019-09-03 |
| ES2521065T3 (es) | 2014-11-12 |
| US20120135087A1 (en) | 2012-05-31 |
| CN103313716B (zh) | 2016-06-01 |
| CA2819307C (en) | 2018-08-14 |
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