HRP20140773T1 - Farmaceutska kompozicija protiv malarije - Google Patents
Farmaceutska kompozicija protiv malarije Download PDFInfo
- Publication number
- HRP20140773T1 HRP20140773T1 HRP20140773AT HRP20140773T HRP20140773T1 HR P20140773 T1 HRP20140773 T1 HR P20140773T1 HR P20140773A T HRP20140773A T HR P20140773AT HR P20140773 T HRP20140773 T HR P20140773T HR P20140773 T1 HRP20140773 T1 HR P20140773T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition according
- composition
- oil
- buccal
- sublingual
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 4
- 230000000078 anti-malarial effect Effects 0.000 title 1
- 239000003430 antimalarial agent Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 20
- 239000000945 filler Substances 0.000 claims 5
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 4
- 150000003626 triacylglycerols Chemical class 0.000 claims 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 4
- SXYIRMFQILZOAM-HVNFFKDJSA-N dihydroartemisinin methyl ether Chemical compound C1C[C@H]2[C@H](C)CC[C@H]3[C@@H](C)[C@@H](OC)O[C@H]4[C@]32OO[C@@]1(C)O4 SXYIRMFQILZOAM-HVNFFKDJSA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 235000006679 Mentha X verticillata Nutrition 0.000 claims 2
- 235000002899 Mentha suaveolens Nutrition 0.000 claims 2
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000007513 acids Chemical class 0.000 claims 2
- 229960000981 artemether Drugs 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 235000021323 fish oil Nutrition 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- 235000003441 saturated fatty acids Nutrition 0.000 claims 2
- 150000004671 saturated fatty acids Chemical class 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims 1
- 235000019501 Lemon oil Nutrition 0.000 claims 1
- 235000014749 Mentha crispa Nutrition 0.000 claims 1
- 244000078639 Mentha spicata Species 0.000 claims 1
- 235000004357 Mentha x piperita Nutrition 0.000 claims 1
- 241001479543 Mentha x piperita Species 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 235000019502 Orange oil Nutrition 0.000 claims 1
- 239000010634 clove oil Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000001647 drug administration Methods 0.000 claims 1
- 239000010501 lemon oil Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 201000004792 malaria Diseases 0.000 claims 1
- 229940057917 medium chain triglycerides Drugs 0.000 claims 1
- 239000001771 mentha piperita Substances 0.000 claims 1
- 239000001220 mentha spicata Substances 0.000 claims 1
- 229940041616 menthol Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000010502 orange oil Substances 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims 1
- 235000012141 vanillin Nutrition 0.000 claims 1
- 239000000341 volatile oil Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Claims (15)
1. Farmaceutska kompozicija naznačena time što sadrži:
artemetar ili arteetar; i
farmaceutski prihvatljiv inertni punitelj izabran iz grupe koju čine:
triglideridi srednje dužine lanca;
trigliceridi kratkog lanca;
omega-3 trigliceridi porijeklom iz mora; i
riblje ulje, bogato omega-3-kiselinama
pri čemu je navedena kompozicija formulirana za transmukozalnu subligvalnu, bukalnu ili nazalnu dozu.
2. Kompozicija prema patentnom zahtjevu 1 naznačena time što se uglavnom sastoji od:
artemetra ili arteetra; i
jednog ili više farmaceutski prihvatljivih inertnih punitelja izabranih iz grupe koju čine:
triglideridi srednje dužine lanca;
trigliceridi kratkog lanca;
omega-3 trigliceridi porijeklom iz mora; i
riblje ulje, bogato omega-3-kiselinama
pri čemu je navedena kompozicija formulirana za transmukozalnu subligvalnu, bukalnu ili nazalnu dozu.
3. Kompozicija prema patentnom zahtjevu 1 naznačena time što se uglavnom sastoji od:
artemetra ili arteetra; i
farmaceutski prihvatljivog inertnog punitelja izabranog iz grupe koju čine:
trigliderid tekući na 37°C; i
trigliceridi srednje dužine lanca;
pri čemu je navedena kompozicija formulirana za transmukozalnu subligvalnu, bukalnu ili nazalnu dozu.
4. Kompozicija prema bilo kojem prethodnom patentnom zahtjevu, naznačena time što je značajno bez vode i/ili etanola.
5. Kompozicija prema bilo kojem prethodnom patentnom zahtjevu, naznačena time što je artemetar ili arteetar prisutan u koncentraciji od između 2 i 250 miligrama po gramu inertnog punitelja.
6. Kompozicija prema bilo kojem prethodnom patentnom zahtjevu, naznačena time što navedeni inertni punitelj sadrži triglicerid srednje dužine lanca, pri čemu navedeni triglicerid sadrži minimalno 95 postotaka zasićenih masnih kiselina sa između 6 i 12 atoma ugljika.
7. Kompozicija prema patentnom zahtjevu 6, naznačena time što navedeni triglicerid sadrži minimalno 95 postotaka zasićenih masnih kiselina sa 8 i 10 atoma ugljika.
8. Kompozicija prema bilo kojem prethodnom patentnom zahtjevu, naznačena time što dalje sadrži eterično ulje kao što je mentol, vanilin ili ulje narandže, ulje limuna, ulje karanfilića, ulje nane Mentha piperita, ulje nane Mentha spicata.
9. Kompozicija prema bilo kojem prethodnom patentnom zahtjevu formulirana za subligvalnu primjenu.
10. Uređaj za primjenu lijeka naznačen time što sadrži kompoziciju prema bilo kojem prethodnom patentnom zahtjevu, pri čemu je navedeni uređaj prilagođen za primjenu pojedinačnih ili uzastopnih doza navedene kompozicije, pri čemu svaka pojedinačna ili uzastopna doza ima volumenu manji od 1000 mikrolitara.
11. Uređaj za primjenu lijeka naznačen time što sadrži kompoziciju prema bilo kojem od patentnih zahtjeva 1 do 9, pri čemu je navedeni uređaj prilagođen za primjenu pojedinačnih ili uzastopnih doza navedene kompozicije, pri čemu pojedinačna ili uzastopna doza sadrži ne više od 80 mg artemetra ili arteetra, poželjno ne više od 10 mg artmemetra ili arteetra.
12. Uređaj za primjenu prema patentnom zahtjevu 10 ili 11 naznačen time što navedeni uređaj sadrži sprej pumpu, poželjno gdje je navedeni uređaj prilagođen da proizvodi sprej od kompozicije koji ima prosječni dijametar kapljice veći od 20 mikrona.
13. Uređaj za osiguravanje farmaceutskih doza naznačen time što sadrži spremnik koji sadrži farmaceutsku kompoziciju prema bilo kojem od patentnih zahtjeva 1 do 9, i sredstva u vidu ventila raspoređena za prijenos doza navedene farmaceutske kompozicije do vanjskog dijela spremnika.
14. Komplet za liječenje ili profilaksu malarije naznačen time što sadrži kompoziciju prema bilo kojem od patentnih zahtjeva 1 do 9 i uputstva za primjenu navedene kompozicije na pacijenta kod kojeg postoji potreba za tim preko transmukozalnog subligvalnog, bukalnog ili nazalnog puta, poželjno preko sublingvalnog puta.
15. Kompozicija prema bilo kojem od patentnih zahtjeva 1 do 9 za uporabu u postupku za liječenje ljudskog ili životinjskog tijela terapijom, gdje se u navedenom liječenju kompozicija primjenjuje preko transmukozalnog sublingvalnog, bukalnog ili nazalnog puta.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0720967.9A GB0720967D0 (en) | 2007-10-25 | 2007-10-25 | Anti-material pharmaceutical composition |
| GBGB0806510.4A GB0806510D0 (en) | 2007-10-25 | 2008-04-10 | Anti-malarial pharmaceutical composition |
| PCT/GB2008/050999 WO2009053758A1 (en) | 2007-10-25 | 2008-10-27 | Anti-malarial pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20140773T1 true HRP20140773T1 (hr) | 2014-11-07 |
Family
ID=38829944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20140773AT HRP20140773T1 (hr) | 2007-10-25 | 2014-08-18 | Farmaceutska kompozicija protiv malarije |
Country Status (26)
| Country | Link |
|---|---|
| US (5) | US20110015260A1 (hr) |
| EP (3) | EP2653153B1 (hr) |
| JP (2) | JP5438018B2 (hr) |
| CN (2) | CN103622950B (hr) |
| AP (2) | AP2920A (hr) |
| AU (1) | AU2008315767B2 (hr) |
| BR (2) | BRPI0817833A8 (hr) |
| CA (1) | CA2702506C (hr) |
| CY (1) | CY1116759T1 (hr) |
| DK (1) | DK2209464T3 (hr) |
| EA (2) | EA026281B1 (hr) |
| ES (2) | ES2540727T3 (hr) |
| GB (3) | GB0720967D0 (hr) |
| HK (1) | HK1190645A1 (hr) |
| HR (1) | HRP20140773T1 (hr) |
| MX (1) | MX2010004392A (hr) |
| MY (2) | MY161745A (hr) |
| NZ (1) | NZ584672A (hr) |
| PE (1) | PE20091322A1 (hr) |
| PH (2) | PH12010500880A1 (hr) |
| PL (1) | PL2209464T3 (hr) |
| PT (1) | PT2209464E (hr) |
| RS (1) | RS53507B1 (hr) |
| SI (1) | SI2209464T1 (hr) |
| WO (1) | WO2009053758A1 (hr) |
| ZA (1) | ZA201002607B (hr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140256761A1 (en) * | 2009-04-22 | 2014-09-11 | Robert Lewis Steele | Enhanced artemisinin-based combination therapy for treating parasitic mediated disease |
| GB2469792A (en) * | 2009-04-23 | 2010-11-03 | Calvin John Ross | Oil-based pharmaceutical formulation for sublingual delivery |
| GB2469791B (en) * | 2009-04-23 | 2011-12-14 | Londonpharma Ltd | Transmucosal formulation of compounds providing dihydroartemesinin for use in the treatment of neoplastic disease |
| US20120058158A1 (en) * | 2009-04-23 | 2012-03-08 | Londonpharma Ltd. | Sublingual Pharmaceutical Composition Comprising a Neutral Oil |
| US8290525B2 (en) | 2010-01-15 | 2012-10-16 | Comcast Cable Communications, Llc | Text alternative to established voice call session |
| US8481757B2 (en) * | 2010-02-04 | 2013-07-09 | Georgua Tech Research Corporation | Compounds and compositions useful in the treatment of malaria |
| US20140256762A1 (en) * | 2012-07-06 | 2014-09-11 | Robert Lewis Steele | Artemisinin-based combination therapy for treating viral mediated disease |
| TWI733649B (zh) * | 2014-03-07 | 2021-07-21 | 巴哈馬商克利普頓集團公司 | 用於治療寄生蟲介導疾病之強化的基於青蒿素組合療法 |
| GB201414918D0 (en) * | 2014-08-21 | 2014-10-08 | Corbitt Terence Simon | Formulations for transmucosal delivery |
| GB201414919D0 (en) * | 2014-08-21 | 2014-10-08 | Corbitt Terence Simon | Formulations for transmucosal delivery |
| US20170326102A1 (en) * | 2014-11-27 | 2017-11-16 | Cipla Limited | Pharmaceutical Composition Comprising an Artemisinin Derivative for Nasal or Pulmonary Delivery |
| US20220280734A1 (en) * | 2021-03-07 | 2022-09-08 | Sultan A. M. Daham | Intaking an antiviral by inhalation or spraying for respiratory tract infection |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0240484B1 (de) * | 1986-03-10 | 1992-01-15 | Kurt Dr. Burghart | Pharmazeutische Zubereitung sowie Verfahren zur Herstellung derselben |
| US5057501A (en) * | 1990-03-13 | 1991-10-15 | Dermatologic Research Corporation | Methods for treatment of papulosquamous and eczematous diseases |
| US20020099067A1 (en) * | 1993-07-08 | 2002-07-25 | Ulrich Posanski | Pharmaceutical compositions for sparingly soluble therapeutic agents |
| US5578637A (en) * | 1995-05-03 | 1996-11-26 | University Of Washington | Methods of inhibition or killing cancer cells using an endoperoxide |
| US20050281752A1 (en) * | 1997-10-01 | 2005-12-22 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
| US20030095926A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract |
| CH692321A5 (de) | 1997-11-03 | 2002-05-15 | Mepha Ag | Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält. |
| RU2129809C1 (ru) * | 1998-04-24 | 1999-05-10 | Захарчук Анатолий Васильевич | Способ получения пищевого продукта в капсулах |
| CN1084333C (zh) * | 1998-06-17 | 2002-05-08 | 中国科学院上海药物研究所 | 新的青蒿素化合物,其制备方法以及含有它们的药物组合物 |
| NZ509324A (en) * | 1998-07-14 | 2003-07-25 | Bayer Ag | Antiparasitic artemisinin derivatives (endoperoxides) |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| ES2153786B1 (es) * | 1999-06-10 | 2001-10-16 | S A L V A T Lab Sa | Composicion farmaceutica liquida para la administracion oral de principios activos amargos y susceptibles de hidrolisis. |
| FR2796276B1 (fr) * | 1999-07-15 | 2003-05-16 | Oreal | Composition sous forme solide comprenant une huile et un compose gelifiant particulier, procede de traitement cosmetique et utilisation dudit compose |
| US6617356B2 (en) * | 2000-01-03 | 2003-09-09 | Naturally Scientific Inc | Gel system for oral and topical administration of water insoluble and/or water intolerant drugs and supplements |
| JP3752127B2 (ja) * | 2000-03-21 | 2006-03-08 | 花王株式会社 | 油脂組成物 |
| EP1408775A2 (en) * | 2000-06-02 | 2004-04-21 | Forbes Medi-Tech Inc. | Oil compositions comprising short, medium and long chain triglycerides and use thereof in reducing weight gain |
| JPWO2002032905A1 (ja) * | 2000-10-20 | 2004-02-26 | 味の素株式会社 | マラリア治療のための医薬組成物、ドーズおよび方法 |
| US6951846B2 (en) * | 2002-03-07 | 2005-10-04 | The United States Of America As Represented By The Secretary Of The Army | Artemisinins with improved stability and bioavailability for therapeutic drug development and application |
| JP4865330B2 (ja) * | 2002-12-13 | 2012-02-01 | デュレクト コーポレーション | 経口ドラッグデリバリーシステム |
| JP2004307428A (ja) * | 2003-04-10 | 2004-11-04 | Porien Project Kk | 原虫感染症予防治療薬 |
| US20050042281A1 (en) * | 2003-08-21 | 2005-02-24 | Singh Nikhilesh N. | Compositions for delivering therapeutic agents across the oral mucosa |
| CN101005828B (zh) * | 2004-06-17 | 2012-01-11 | 维尔恩公司 | 用于经粘膜递送活性成分的包含粘膜粘附蛋白和所述活性物质的组合物 |
| CN1650854A (zh) * | 2004-12-08 | 2005-08-10 | 广州中生生物技术有限公司 | 一种含有蒿甲醚（或蒿乙醚或蒿琥酯）微乳剂的制备工艺 |
| US20060233895A1 (en) * | 2005-04-15 | 2006-10-19 | Brown Paul R | Herbal remedy for treating Lyme disease |
| KR20080028361A (ko) * | 2005-05-03 | 2008-03-31 | 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. | 퀴닌-함유 제어-방출형 제제 |
| SI1933809T1 (sl) * | 2005-10-11 | 2012-08-31 | Yissum Res Dev Co | Sestavki za mazalno dajanje |
| DK1976521T3 (en) * | 2006-01-25 | 2015-04-27 | Insys Therapeutics Inc | Sublingual fentanyl spray |
| CN101310720A (zh) * | 2007-05-22 | 2008-11-26 | 天津丹溪国药研究所 | 一种治疗疟疾的蒿甲醚滴丸剂的制备方法 |
| CN101317839A (zh) * | 2007-06-05 | 2008-12-10 | 天津丹溪国药研究所 | 一种治疗疟疾的复方蒿甲醚滴丸剂的制备方法 |
| RS52430B (en) * | 2009-04-23 | 2013-02-28 | Londonpharma Ltd. | SUBLINGVAL FORMULATION OF DIHIDROARTEMEZININE CONTAINING SPRAY |
| US20120058158A1 (en) * | 2009-04-23 | 2012-03-08 | Londonpharma Ltd. | Sublingual Pharmaceutical Composition Comprising a Neutral Oil |
| GB2481619B (en) * | 2010-06-30 | 2012-06-20 | Londonpharma Ltd | Formulations and delivery devices for the sublingual administration of opioids |
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2007
- 2007-10-25 GB GBGB0720967.9A patent/GB0720967D0/en not_active Ceased
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2008
- 2008-04-10 GB GBGB0806510.4A patent/GB0806510D0/en not_active Ceased
- 2008-10-27 EP EP13176933.3A patent/EP2653153B1/en not_active Not-in-force
- 2008-10-27 ES ES13176933.3T patent/ES2540727T3/es active Active
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