EA201300151A1 - Противомалярийная фармацевтическая композиция - Google Patents

Противомалярийная фармацевтическая композиция

Info

Publication number
EA201300151A1
EA201300151A1 EA201300151A EA201300151A EA201300151A1 EA 201300151 A1 EA201300151 A1 EA 201300151A1 EA 201300151 A EA201300151 A EA 201300151A EA 201300151 A EA201300151 A EA 201300151A EA 201300151 A1 EA201300151 A1 EA 201300151A1
Authority
EA
Eurasian Patent Office
Prior art keywords
malary
pharmaceutical composition
delivery
proposed
malaria
Prior art date
Application number
EA201300151A
Other languages
English (en)
Other versions
EA026281B1 (ru
Inventor
Клайв Булс
Калвин Росс
Мартин Самс
Original Assignee
Протофарма Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Протофарма Лимитед filed Critical Протофарма Лимитед
Publication of EA201300151A1 publication Critical patent/EA201300151A1/ru
Publication of EA026281B1 publication Critical patent/EA026281B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Согласно изобретению предложены фармацевтические композиции для лечения и профилактики малярии, содержащие артеметер и триглицерид с цепью средней длины, изготовленные для трансмукозальной сублингвальной, трансбуккальной или назальной доставки, в особенности посредством распыления. Кроме того, предложены устройства для доставки, содержащие данные композиции.
EA201300151A 2007-10-25 2008-10-27 Способ лечения или предупреждения малярии EA026281B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0720967.9A GB0720967D0 (en) 2007-10-25 2007-10-25 Anti-material pharmaceutical composition
GBGB0806510.4A GB0806510D0 (en) 2007-10-25 2008-04-10 Anti-malarial pharmaceutical composition

Publications (2)

Publication Number Publication Date
EA201300151A1 true EA201300151A1 (ru) 2013-10-30
EA026281B1 EA026281B1 (ru) 2017-03-31

Family

ID=38829944

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201300151A EA026281B1 (ru) 2007-10-25 2008-10-27 Способ лечения или предупреждения малярии
EA201000497A EA017804B1 (ru) 2007-10-25 2008-10-27 Противомалярийная фармацевтическая композиция

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201000497A EA017804B1 (ru) 2007-10-25 2008-10-27 Противомалярийная фармацевтическая композиция

Country Status (26)

Country Link
US (5) US20110015260A1 (ru)
EP (3) EP2209464B1 (ru)
JP (2) JP5438018B2 (ru)
CN (2) CN103622950B (ru)
AP (2) AP3542A (ru)
AU (1) AU2008315767B2 (ru)
BR (2) BR122013005952A2 (ru)
CA (1) CA2702506C (ru)
CY (1) CY1116759T1 (ru)
DK (1) DK2209464T3 (ru)
EA (2) EA026281B1 (ru)
ES (2) ES2540727T3 (ru)
GB (3) GB0720967D0 (ru)
HK (1) HK1190645A1 (ru)
HR (1) HRP20140773T1 (ru)
MX (1) MX2010004392A (ru)
MY (2) MY153119A (ru)
NZ (1) NZ584672A (ru)
PE (1) PE20091322A1 (ru)
PH (2) PH12010500880A1 (ru)
PL (1) PL2209464T3 (ru)
PT (1) PT2209464E (ru)
RS (1) RS53507B1 (ru)
SI (1) SI2209464T1 (ru)
WO (1) WO2009053758A1 (ru)
ZA (1) ZA201002607B (ru)

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GB201414918D0 (en) * 2014-08-21 2014-10-08 Corbitt Terence Simon Formulations for transmucosal delivery
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US20220280734A1 (en) * 2021-03-07 2022-09-08 Sultan A. M. Daham Intaking an antiviral by inhalation or spraying for respiratory tract infection

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Also Published As

Publication number Publication date
ES2540727T3 (es) 2015-07-13
EA017804B1 (ru) 2013-03-29
MY161745A (en) 2017-05-15
CN103622950B (zh) 2016-05-04
HRP20140773T1 (hr) 2014-11-07
PH12010500880A1 (ru) 2014-10-07
GB0819559D0 (en) 2008-12-03
BRPI0817833A2 (pt) 2015-03-31
GB2454567B (en) 2010-06-30
BR122013005952A2 (pt) 2015-07-14
MX2010004392A (es) 2010-06-25
BRPI0817833A8 (pt) 2015-09-15
JP2014088400A (ja) 2014-05-15
ES2494340T3 (es) 2014-09-15
JP5438018B2 (ja) 2014-03-12
PL2209464T3 (pl) 2014-11-28
GB2454567A (en) 2009-05-13
RS53507B1 (en) 2015-02-27
SI2209464T1 (sl) 2014-11-28
CN101835464A (zh) 2010-09-15
EA026281B1 (ru) 2017-03-31
PE20091322A1 (es) 2009-10-04
EP2209464B1 (en) 2014-06-04
JP2011500781A (ja) 2011-01-06
CN103622950A (zh) 2014-03-12
EP2653153B1 (en) 2015-05-27
US20160038404A1 (en) 2016-02-11
US20140179772A1 (en) 2014-06-26
PH12013501567B1 (en) 2014-10-08
CA2702506C (en) 2015-08-25
US20180071207A1 (en) 2018-03-15
GB0720967D0 (en) 2007-12-05
WO2009053758A1 (en) 2009-04-30
EP2209464A1 (en) 2010-07-28
MY153119A (en) 2014-12-31
CA2702506A1 (en) 2009-04-30
NZ584672A (en) 2012-03-30
AP2920A (en) 2014-05-31
US20110015260A1 (en) 2011-01-20
EP2653153A1 (en) 2013-10-23
AP2010005231A0 (en) 2010-04-30
EA201000497A1 (ru) 2010-12-30
GB0806510D0 (en) 2008-05-14
PT2209464E (pt) 2014-09-05
HK1190645A1 (zh) 2014-07-11
AP3542A (en) 2016-01-13
US20190290576A1 (en) 2019-09-26
CN101835464B (zh) 2013-05-15
DK2209464T3 (da) 2014-08-25
AU2008315767B2 (en) 2013-11-07
PH12013501567A1 (en) 2014-10-08
CY1116759T1 (el) 2017-03-15
AU2008315767A1 (en) 2009-04-30
ZA201002607B (en) 2011-10-26
EP2749267A1 (en) 2014-07-02
AP2013006997A0 (en) 2013-07-31

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