HRP20130618T1 - Methods of using mirna for detection of in vivo cell death - Google Patents

Methods of using mirna for detection of in vivo cell death

Info

Publication number
HRP20130618T1
HRP20130618T1 HRP20130618AT HRP20130618T HRP20130618T1 HR P20130618 T1 HRP20130618 T1 HR P20130618T1 HR P20130618A T HRP20130618A T HR P20130618AT HR P20130618 T HRP20130618 T HR P20130618T HR P20130618 T1 HRP20130618 T1 HR P20130618T1
Authority
HR
Croatia
Prior art keywords
cell death
detection
mirna
methods
vivo cell
Prior art date
Application number
HRP20130618AT
Other languages
English (en)
Croatian (hr)
Inventor
Eugene M. Shekhtman
Hovsep S. Melkonyan
Samuil R. Umansky
Vladimir S. Scheinker
Original Assignee
Trovagene, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40378881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20130618(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trovagene, Inc. filed Critical Trovagene, Inc.
Publication of HRP20130618T1 publication Critical patent/HRP20130618T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HRP20130618AT 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death HRP20130618T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96587107P 2007-08-22 2007-08-22
PCT/US2008/009991 WO2009025852A2 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death

Publications (1)

Publication Number Publication Date
HRP20130618T1 true HRP20130618T1 (en) 2013-07-31

Family

ID=40378881

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20130618AT HRP20130618T1 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death

Country Status (16)

Country Link
US (4) US8486626B2 (https=)
EP (2) EP2195450B2 (https=)
JP (1) JP5416110B2 (https=)
CN (2) CN105400868B (https=)
AU (2) AU2008289447B2 (https=)
CA (1) CA2696403C (https=)
CY (1) CY1114111T1 (https=)
DK (2) DK2612926T3 (https=)
ES (2) ES2660785T3 (https=)
HR (1) HRP20130618T1 (https=)
HU (1) HUE019019T5 (https=)
NO (1) NO2612926T3 (https=)
PL (2) PL2612926T3 (https=)
PT (2) PT2612926T (https=)
TR (1) TR201802758T4 (https=)
WO (1) WO2009025852A2 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132273A2 (en) * 2008-04-25 2009-10-29 Merck & Co., Inc. Microrna biomarkers of tissue injury
WO2010004562A2 (en) * 2008-07-09 2010-01-14 Rosetta Genomics Ltd. Methods and compositions for detecting colorectal cancer
EP2853601B1 (en) * 2008-07-18 2016-09-21 TrovaGene, Inc. Methods for PCR-based detection of "ultra short" nucleic acid sequences
EP2419536A4 (en) * 2009-04-14 2012-09-05 Merck Sharp & Dohme MICRO RNA AS A BIOMARKER FOR IMPROVING BETAZELLES IN THE PANCREAS ISLANDS
WO2011006119A2 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
US8648017B2 (en) * 2009-11-04 2014-02-11 Diamir, Llc Methods of using small RNA from bodily fluids for diagnosis and monitoring of neurodegenerative diseases
JP2013509883A (ja) 2009-11-06 2013-03-21 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 臓器移植患者における移植片拒絶反応の非侵襲的診断方法
WO2011143659A2 (en) * 2010-05-14 2011-11-17 Fluidigm Corporation Nucleic acid isolation methods
RU2626540C2 (ru) 2011-04-18 2017-07-28 Диамир, Ллс Способы обнаружения патологических изменений в органе или системе органов
CN102188719B (zh) * 2011-05-12 2012-12-19 南方医科大学 EB病毒miR-BART3反义寡聚核苷酸在制备治疗鼻咽癌的药物中的应用
RU2639509C2 (ru) 2011-06-27 2017-12-21 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. МикроРНК - БИОМАРКЕРЫ, УКАЗЫВАЮЩИЕ НА БОЛЕЗНЬ АЛЬЦГЕЙМЕРА
CA2838562A1 (en) * 2011-08-08 2013-02-14 Eugenia Wang Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof
CA3069089A1 (en) * 2011-09-22 2013-03-28 Lineage Biosciences, Inc. Compositions and methods for analyzing heterogeneous samples
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
US20160289762A1 (en) 2012-01-27 2016-10-06 The Board Of Trustees Of The Leland Stanford Junior University Methods for profiliing and quantitating cell-free rna
HK1211624A1 (en) 2012-01-27 2016-05-27 The Board Of Trustees Of The University Of The Leland Stanford Junior University Methods for profiling and quantitating cell-free rna
US20140087964A1 (en) * 2012-09-24 2014-03-27 University Of Virginia Patent Foundation Compositions and methods for detecting aberrant regulation, expression, and levels of hgh
EP2733220B1 (en) * 2012-11-16 2017-10-18 Siemens Aktiengesellschaft Novel miRNA as a diagnostic marker for Alzheimer's Disease
WO2014075822A1 (en) * 2012-11-16 2014-05-22 Siemens Aktiengesellschaft New diagnostic mirna markers for parkinson disease
EP2733219B1 (en) 2012-11-16 2017-09-20 Siemens Aktiengesellschaft Diagnostic miRNA markers for Alzheimer
CN103045736B (zh) * 2012-12-20 2014-09-17 徐勇 唐氏综合征21号染色体miRNA差异表达图谱模型、构建方法及应用
CN103045596A (zh) * 2012-12-20 2013-04-17 徐勇 唐氏综合征21号染色体相关miRNA、基因、筛选方法和应用
EP2759602A1 (en) * 2013-01-25 2014-07-30 Charité - Universitätsmedizin Berlin Non-invasive prenatal genetic diagnostic methods
EP3611262B1 (en) 2013-03-15 2020-11-11 Lineage Biosciences, Inc. Methods of sequencing the immune repertoire
CN105917005B (zh) 2013-11-18 2020-09-11 迪阿米尔有限责任公司 使用来自体液的miRNA检测和监控帕金森病(PD)的方法
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
TWI813141B (zh) 2014-07-18 2023-08-21 香港中文大學 Ｄｎａ混合物中之組織甲基化模式分析
JP6873921B2 (ja) 2015-05-18 2021-05-19 カリウス・インコーポレイテッド 核酸の集団を濃縮するための組成物および方法
WO2017019751A1 (en) 2015-07-27 2017-02-02 The Johns Hopkins University Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: pcr and sequencing based process methods
JP2018526021A (ja) * 2015-09-11 2018-09-13 コーニング インコーポレイテッド 血液試料からの核酸精製のための組成物及び方法
US10975436B2 (en) 2016-01-05 2021-04-13 Diamir, Llc Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders
US11149313B2 (en) 2016-03-21 2021-10-19 Diamir, Llc Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases
WO2018045359A1 (en) * 2016-09-02 2018-03-08 Karius, Inc. Detection and treatment of infection during pregnancy
WO2018090054A1 (en) 2016-11-14 2018-05-17 Berg Llc Methods for treating parkinson's disease
KR20260032575A (ko) 2016-11-30 2026-03-09 더 차이니즈 유니버시티 오브 홍콩 소변 및 기타 샘플에서의 무세포 dna의 분석
US10907211B1 (en) 2017-02-16 2021-02-02 Quantgene Inc. Methods and compositions for detecting cancer biomarkers in bodily fluids
US10781487B2 (en) 2017-07-24 2020-09-22 Diamir, Llc miRNA-based methods for detecting and monitoring aging
GB2615975B (en) 2019-02-14 2023-11-29 Mirvie Inc Methods and systems for determining a pregnancy-related state of a subject
KR102802718B1 (ko) * 2019-10-29 2025-04-30 고쿠리츠켄큐카이하츠호진 고쿠리츠쥰칸키뵤 겐큐센터 뇌경색 치료 지원 시스템
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856088A (en) * 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5168039A (en) * 1990-09-28 1992-12-01 The Board Of Trustees Of The University Of Arkansas Repetitive DNA sequence specific for mycobacterium tuberculosis to be used for the diagnosis of tuberculosis
US6020124A (en) * 1992-04-27 2000-02-01 Trustees Of Dartmouth College Detection of soluble gene sequences in biological fluids
JP3435163B2 (ja) * 1993-07-20 2003-08-11 ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 黒色腫阻害蛋白質
AU7375794A (en) 1993-07-28 1995-02-28 Akzo Nobel N.V. Process for isolating nucleic acid from gram positive microorganisms
CA2170604C (en) * 1993-08-30 2007-03-13 Vikas V. Padhye Nucleic acid purification compositions and methods
US5631130A (en) * 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
AU703947B2 (en) * 1994-06-09 1999-04-01 Innogenetics N.V. Method for the detection of the antibiotic resistance spectrum of mycobacterium species
US5731150A (en) * 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
US6492144B1 (en) * 1997-05-30 2002-12-10 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US6251638B1 (en) * 1997-05-30 2001-06-26 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US20020119478A1 (en) * 1997-05-30 2002-08-29 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US5962665A (en) 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US20060204989A1 (en) † 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
US7196183B2 (en) * 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US20040053264A1 (en) * 2002-02-01 2004-03-18 Park Sung Sup Clinical panel assay using DNA chips
EP2290073A3 (en) * 2004-05-28 2011-08-31 Asuragen, Inc. Methods and compositions involving microRNA
WO2006089203A2 (en) 2005-02-17 2006-08-24 Istituto Nazionale Per Le Malattie Infettive Irccs Lazzaro Spallanzani Compositions and methods for detecting viral specific nucleic acids in urine
ITRM20050067A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
EP2351857B1 (en) 2005-02-17 2014-10-29 TrovaGene, Inc. Compositions and methods for detecting pathogen specific nucleic acids in urine
ITRM20050068A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
US20060292616A1 (en) * 2005-06-23 2006-12-28 U.S. Genomics, Inc. Single molecule miRNA-based disease diagnostic methods
DE102005059315A1 (de) * 2005-12-09 2007-06-14 Qiagen Gmbh Verfahren zur Anreicherung von kurzkettigen Nukleinsäuren
US20070202511A1 (en) * 2006-02-28 2007-08-30 Sigma-Aldrich Co. Methods and compositions for the rapid isolation of small RNA molecules
EP2853601B1 (en) * 2008-07-18 2016-09-21 TrovaGene, Inc. Methods for PCR-based detection of "ultra short" nucleic acid sequences

Also Published As

Publication number Publication date
ES2415245T5 (es) 2016-12-23
AU2008289447A1 (en) 2009-02-26
CA2696403C (en) 2018-01-02
US20200283851A1 (en) 2020-09-10
EP2612926A1 (en) 2013-07-10
JP5416110B2 (ja) 2014-02-12
US20150197805A1 (en) 2015-07-16
WO2009025852A3 (en) 2009-05-07
EP2195450B2 (en) 2016-07-20
PT2195450E (pt) 2013-07-10
CN101861399A (zh) 2010-10-13
PL2195450T3 (pl) 2013-09-30
HUE019019T5 (en) 2017-04-28
DK2612926T3 (en) 2018-03-12
DK2195450T4 (en) 2016-10-24
CN101861399B (zh) 2015-11-25
PL2612926T3 (pl) 2018-07-31
CN105400868B (zh) 2021-03-26
EP2195450B1 (en) 2013-04-03
PT2612926T (pt) 2018-03-02
EP2195450A2 (en) 2010-06-16
EP2612926B1 (en) 2017-11-29
CY1114111T1 (el) 2016-07-27
ES2660785T3 (es) 2018-03-26
ES2415245T3 (es) 2013-07-24
NO2612926T3 (https=) 2018-04-28
TR201802758T4 (tr) 2018-03-21
US8486626B2 (en) 2013-07-16
US20090081640A1 (en) 2009-03-26
AU2014210676A1 (en) 2014-08-28
DK2195450T3 (da) 2013-06-24
WO2009025852A2 (en) 2009-02-26
AU2008289447B2 (en) 2014-09-04
US20180135126A1 (en) 2018-05-17
JP2010536372A (ja) 2010-12-02
CN105400868A (zh) 2016-03-16
AU2014210676B2 (en) 2017-04-06
CA2696403A1 (en) 2009-02-26
HK1218767A1 (zh) 2017-03-10

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