HRP20120591T1 - Postupci proizvodnje mikrofolikula kose i de novo papila i njihova uporaba za in vitro testiranja i in vivo implantacije - Google Patents
Postupci proizvodnje mikrofolikula kose i de novo papila i njihova uporaba za in vitro testiranja i in vivo implantacije Download PDFInfo
- Publication number
- HRP20120591T1 HRP20120591T1 HRP20120591AT HRP20120591T HRP20120591T1 HR P20120591 T1 HRP20120591 T1 HR P20120591T1 HR P20120591A T HRP20120591A T HR P20120591AT HR P20120591 T HRP20120591 T HR P20120591T HR P20120591 T1 HRP20120591 T1 HR P20120591T1
- Authority
- HR
- Croatia
- Prior art keywords
- dpfs
- novo
- novo papillae
- papillae
- providing
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 10
- 210000004209 hair Anatomy 0.000 title claims abstract 4
- 238000002513 implantation Methods 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 claims abstract 7
- 210000002950 fibroblast Anatomy 0.000 claims abstract 4
- 210000002510 keratinocyte Anatomy 0.000 claims abstract 3
- 210000002752 melanocyte Anatomy 0.000 claims abstract 3
- 238000004519 manufacturing process Methods 0.000 claims abstract 2
- 102000008186 Collagen Human genes 0.000 claims 3
- 108010035532 Collagen Proteins 0.000 claims 3
- 229920001436 collagen Polymers 0.000 claims 3
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 2
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 2
- 102000016359 Fibronectins Human genes 0.000 claims 2
- 108010067306 Fibronectins Proteins 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 230000002500 effect on skin Effects 0.000 claims 2
- 210000003780 hair follicle Anatomy 0.000 claims 2
- 230000001464 adherent effect Effects 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 238000004873 anchoring Methods 0.000 claims 1
- 210000002469 basement membrane Anatomy 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 210000002808 connective tissue Anatomy 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 230000005012 migration Effects 0.000 claims 1
- 238000013508 migration Methods 0.000 claims 1
- 238000004264 monolayer culture Methods 0.000 claims 1
- 238000004115 adherent culture Methods 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3869—Epithelial tissues other than skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0627—Hair cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/092—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells hair cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compounds Of Unknown Constitution (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08153596A EP2105499A1 (en) | 2008-03-28 | 2008-03-28 | Methods for producing de novo papillae and hair microfollicles and their use for in vitro tests and in vivo implantations |
| PCT/EP2009/053363 WO2009118283A1 (en) | 2008-03-28 | 2009-03-23 | Methods for producing hair microfollicles and de novo papillae and their use for in vitro tests and in vivo implantations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120591T1 true HRP20120591T1 (hr) | 2012-08-31 |
Family
ID=39734907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120591AT HRP20120591T1 (hr) | 2008-03-28 | 2012-07-16 | Postupci proizvodnje mikrofolikula kose i de novo papila i njihova uporaba za in vitro testiranja i in vivo implantacije |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8841124B2 (sl) |
| EP (3) | EP2105499A1 (sl) |
| JP (1) | JP5600671B2 (sl) |
| CN (1) | CN102027106B (sl) |
| AT (1) | ATE555192T1 (sl) |
| AU (1) | AU2009228756B2 (sl) |
| CA (1) | CA2719769C (sl) |
| CY (1) | CY1112945T1 (sl) |
| DK (1) | DK2274419T3 (sl) |
| ES (2) | ES2386109T3 (sl) |
| HK (1) | HK1156976A1 (sl) |
| HR (1) | HRP20120591T1 (sl) |
| HU (1) | HUE026065T2 (sl) |
| PL (2) | PL2447357T3 (sl) |
| PT (2) | PT2274419E (sl) |
| RU (1) | RU2507254C2 (sl) |
| SI (1) | SI2274419T1 (sl) |
| WO (1) | WO2009118283A1 (sl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2483622A (en) * | 2009-08-03 | 2012-03-21 | Univ Durham | Fibroblast feeder cells |
| US9321998B2 (en) | 2011-02-24 | 2016-04-26 | Organ Technologies Inc. | Method of preparing regenerated hair follicle germ for transplantation in which hair color is controlled, composition including regenerated hair follicle germ for transplantation, and method of transplanting regenerated hair follicle germ |
| JP2012205516A (ja) | 2011-03-29 | 2012-10-25 | Osaka Univ | 人工皮膚モデルの製造方法、及び人工皮膚モデル |
| WO2014179559A1 (en) | 2013-05-03 | 2014-11-06 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Skin substitutes and methods for hair follicle neogenesis |
| FR3008316B1 (fr) * | 2013-07-09 | 2020-01-31 | Assistance Publique - Hopitaux De Paris | Utilisation de fibroblastes gingivaux dans le traitement de l'alopecie |
| WO2015066618A1 (en) * | 2013-11-01 | 2015-05-07 | The Florida International University Board Of Trustees | Context based algorithmic framework for identifying and classifying embedded images of follicle units |
| SG11201707858TA (en) * | 2015-03-30 | 2017-10-30 | Ajinomoto Kk | Human serum albumin-containing culture medium for growth of neural stem cells |
| FR3041656A1 (fr) * | 2015-09-29 | 2017-03-31 | Oreal | Utilisation des cellules de la matrice pour la preparation d'un microfollicule pileux |
| DE102015119880B4 (de) | 2015-11-17 | 2018-05-24 | Technische Universität Berlin | Verfahren zur Herstellung von Haarfollikeln und de novo Papillen sowie deren Verwendung für in vitro Tests und in vivo Implantate |
| DE102015119877B4 (de) * | 2015-11-17 | 2017-09-21 | Technische Universität Berlin | Verfahren zur Herstellung eines Hautäquivalents sowie dessen Verwendung für in vitro Tests und in vivo Transplantate |
| CN105353114B (zh) * | 2015-11-18 | 2017-09-26 | 广东博溪生物科技有限公司 | 一种含黑色素的体外测试皮肤模型及其制备方法 |
| FR3054449B1 (fr) * | 2016-07-29 | 2018-08-31 | L'oreal | Equivalent de peau a compartiments dermiques juxtaposes distincts |
| FR3061207B1 (fr) | 2016-12-23 | 2023-03-10 | Oreal | Utilisation des cellules germinales pour la preparation d’un microfollicule pileux |
| JP2018186719A (ja) * | 2017-04-28 | 2018-11-29 | 株式会社 バイオミメティクスシンパシーズ | 頭皮投与用幹細胞 |
| FR3072972B1 (fr) * | 2017-10-30 | 2023-03-10 | Oreal | Procede de preparation in vitro d’equivalents de papille dermique et de follicule pileux |
| CN109468271A (zh) * | 2018-12-28 | 2019-03-15 | 广州暨大美塑生物科技有限公司 | 一种皮肤组织来源成纤维细胞快速分离培养方法 |
| CN114085804B (zh) * | 2021-11-09 | 2023-12-26 | 南方医科大学皮肤病医院（广东省皮肤病医院、广东省皮肤性病防治中心、中国麻风防治研究中心） | 一种人胚胎干细胞体外诱导分化形成的皮肤类器官及其高效培养方法与用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10162814B4 (de) | 2001-12-19 | 2005-06-23 | Henkel Kgaa | Rekonstruiertes Haarfollikelmodell |
| DE10327879A1 (de) * | 2003-06-18 | 2005-01-05 | Henkel Kgaa | Rekonstruierte dermale Papille |
| US20050233450A1 (en) * | 2004-01-12 | 2005-10-20 | Goetinck Paul F | Methods of inducing hair growth |
| EP2329833A1 (en) | 2004-01-27 | 2011-06-08 | The Hospital for Sick Children Research Institute | Methods of making and using skin-derived stem cells |
| US9375514B2 (en) | 2004-05-21 | 2016-06-28 | Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Multicellular tissue and organ culture systems |
-
2008
- 2008-03-28 EP EP08153596A patent/EP2105499A1/en not_active Withdrawn
-
2009
- 2009-03-23 CN CN200980116851.XA patent/CN102027106B/zh active Active
- 2009-03-23 ES ES09724502T patent/ES2386109T3/es active Active
- 2009-03-23 ES ES12150985.5T patent/ES2549055T3/es active Active
- 2009-03-23 PT PT09724502T patent/PT2274419E/pt unknown
- 2009-03-23 RU RU2010144183/10A patent/RU2507254C2/ru active
- 2009-03-23 SI SI200930296T patent/SI2274419T1/sl unknown
- 2009-03-23 WO PCT/EP2009/053363 patent/WO2009118283A1/en active Application Filing
- 2009-03-23 EP EP12150985.5A patent/EP2447357B1/en active Active
- 2009-03-23 PL PL12150985T patent/PL2447357T3/pl unknown
- 2009-03-23 JP JP2011501184A patent/JP5600671B2/ja active Active
- 2009-03-23 AT AT09724502T patent/ATE555192T1/de active
- 2009-03-23 HU HUE12150985A patent/HUE026065T2/en unknown
- 2009-03-23 CA CA2719769A patent/CA2719769C/en not_active Expired - Fee Related
- 2009-03-23 EP EP09724502A patent/EP2274419B1/en active Active
- 2009-03-23 PL PL09724502T patent/PL2274419T3/pl unknown
- 2009-03-23 US US12/935,172 patent/US8841124B2/en active Active
- 2009-03-23 DK DK09724502.1T patent/DK2274419T3/da active
- 2009-03-23 AU AU2009228756A patent/AU2009228756B2/en not_active Ceased
- 2009-03-23 PT PT121509855T patent/PT2447357E/pt unknown
-
2011
- 2011-10-20 HK HK11111288.5A patent/HK1156976A1/xx unknown
-
2012
- 2012-07-16 HR HRP20120591AT patent/HRP20120591T1/hr unknown
- 2012-07-24 CY CY20121100655T patent/CY1112945T1/el unknown
-
2014
- 2014-08-26 US US14/468,494 patent/US9764064B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2719769C (en) | 2018-05-01 |
| CA2719769A1 (en) | 2009-10-01 |
| EP2274419B1 (en) | 2012-04-25 |
| HUE026065T2 (en) | 2016-05-30 |
| RU2507254C2 (ru) | 2014-02-20 |
| US9764064B2 (en) | 2017-09-19 |
| PT2447357E (pt) | 2015-10-23 |
| RU2010144183A (ru) | 2012-05-10 |
| CN102027106A (zh) | 2011-04-20 |
| EP2447357B1 (en) | 2015-07-01 |
| ES2549055T3 (es) | 2015-10-22 |
| EP2274419A1 (en) | 2011-01-19 |
| DK2274419T3 (da) | 2012-07-23 |
| AU2009228756B2 (en) | 2014-07-24 |
| US20140370070A1 (en) | 2014-12-18 |
| EP2447357A1 (en) | 2012-05-02 |
| PL2447357T3 (pl) | 2015-12-31 |
| CY1112945T1 (el) | 2016-04-13 |
| US8841124B2 (en) | 2014-09-23 |
| SI2274419T1 (sl) | 2012-10-30 |
| ATE555192T1 (de) | 2012-05-15 |
| CN102027106B (zh) | 2014-05-14 |
| AU2009228756A1 (en) | 2009-10-01 |
| WO2009118283A1 (en) | 2009-10-01 |
| ES2386109T3 (es) | 2012-08-09 |
| EP2105499A1 (en) | 2009-09-30 |
| PL2274419T3 (pl) | 2012-10-31 |
| HK1156976A1 (en) | 2012-06-22 |
| JP5600671B2 (ja) | 2014-10-01 |
| JP2011515095A (ja) | 2011-05-19 |
| US20110086079A1 (en) | 2011-04-14 |
| PT2274419E (pt) | 2012-07-06 |
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| JP2011515095A5 (sl) | ||
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| JP2008541734A5 (sl) | ||
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