HRP20120031T1 - Postupak kemijskog spajanja sa derivatom fenil boronske kiseline - Google Patents

Postupak kemijskog spajanja sa derivatom fenil boronske kiseline Download PDF

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Publication number
HRP20120031T1
HRP20120031T1 HR20120031T HRP20120031T HRP20120031T1 HR P20120031 T1 HRP20120031 T1 HR P20120031T1 HR 20120031 T HR20120031 T HR 20120031T HR P20120031 T HRP20120031 T HR P20120031T HR P20120031 T1 HRP20120031 T1 HR P20120031T1
Authority
HR
Croatia
Prior art keywords
butyl
lithium
acid derivative
boronic acid
coupling process
Prior art date
Application number
HR20120031T
Other languages
English (en)
Croatian (hr)
Inventor
Anne Butlin Margaret
John Butlin Roger
John Hogan Philip
Meudt Andreas
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HRP20120031T1 publication Critical patent/HRP20120031T1/hr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
HR20120031T 2004-02-20 2012-01-10 Postupak kemijskog spajanja sa derivatom fenil boronske kiseline HRP20120031T1 (hr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0403744.6A GB0403744D0 (en) 2004-02-20 2004-02-20 Chemical process

Publications (1)

Publication Number Publication Date
HRP20120031T1 true HRP20120031T1 (hr) 2012-02-29

Family

ID=32040047

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20120031T HRP20120031T1 (hr) 2004-02-20 2012-01-10 Postupak kemijskog spajanja sa derivatom fenil boronske kiseline

Country Status (32)

Country Link
US (2) US7626020B2 (pt)
EP (3) EP1718655A2 (pt)
JP (2) JP2007523906A (pt)
KR (2) KR20120036998A (pt)
CN (1) CN1922193B (pt)
AR (1) AR047810A1 (pt)
AT (1) ATE535532T1 (pt)
AU (1) AU2005214138B2 (pt)
BR (1) BRPI0507847A (pt)
CA (1) CA2555554A1 (pt)
CL (1) CL2011003138A1 (pt)
CY (1) CY1112555T1 (pt)
DK (1) DK2135873T3 (pt)
ES (1) ES2375201T3 (pt)
GB (1) GB0403744D0 (pt)
HK (1) HK1139689A1 (pt)
HR (1) HRP20120031T1 (pt)
IL (2) IL177505A (pt)
MY (1) MY142268A (pt)
NO (1) NO20064012L (pt)
PL (1) PL2135873T3 (pt)
PT (1) PT2135873E (pt)
RS (1) RS52300B (pt)
RU (1) RU2386636C2 (pt)
SA (1) SA05260017B1 (pt)
SG (1) SG153856A1 (pt)
SI (1) SI2135873T1 (pt)
TW (1) TWI347947B (pt)
UA (1) UA83418C2 (pt)
UY (1) UY28754A1 (pt)
WO (1) WO2005080403A2 (pt)
ZA (1) ZA200606579B (pt)

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ES2493916T3 (es) 2009-04-07 2014-09-12 Infinity Pharmaceuticals, Inc. Inhibidores de hidrolasa de amida de ácidos grasos
BR112012019120A2 (pt) 2010-02-03 2016-06-28 Infinity Pharmaceuticais Inc forma sólida, composição farmacêutica, método de preparação do composto 1, método de tratamento de uma condição mediada por faah
CN102491973A (zh) * 2011-12-15 2012-06-13 南京友杰医药科技有限公司 Zd-4054的合成方法
ES2893100T3 (es) 2015-10-12 2022-02-08 Advanced Cell Diagnostics Inc Detección in situ de variantes de nucleótidos en muestras con un elevado nivel de ruido, y composiciones y métodos relacionados con ésta

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Also Published As

Publication number Publication date
CN1922193B (zh) 2012-12-26
BRPI0507847A (pt) 2007-07-10
TW200538451A (en) 2005-12-01
RS52300B (en) 2012-12-31
HK1139689A1 (en) 2010-09-24
PT2135873E (pt) 2012-01-16
ATE535532T1 (de) 2011-12-15
AU2005214138B2 (en) 2009-02-12
RU2006133455A (ru) 2008-03-27
WO2005080403A2 (en) 2005-09-01
RU2386636C2 (ru) 2010-04-20
KR20120036998A (ko) 2012-04-18
MY142268A (en) 2010-11-15
WO2005080403A3 (en) 2005-11-24
AU2005214138A1 (en) 2005-09-01
SG153856A1 (en) 2009-07-29
EP2135873A3 (en) 2010-03-24
KR20060129483A (ko) 2006-12-15
EP1718655A2 (en) 2006-11-08
AR047810A1 (es) 2006-02-22
UA83418C2 (uk) 2008-07-10
IL194709A (en) 2010-12-30
EP2135873B1 (en) 2011-11-30
DK2135873T3 (da) 2012-02-13
EP2325189A3 (en) 2011-10-26
ZA200606579B (en) 2008-01-30
SA05260017B1 (ar) 2008-07-14
EP2325189A2 (en) 2011-05-25
KR101196111B1 (ko) 2012-10-30
IL177505A0 (en) 2006-12-10
SI2135873T1 (sl) 2012-03-30
CA2555554A1 (en) 2005-09-01
TWI347947B (en) 2011-09-01
IL177505A (en) 2010-12-30
CN1922193A (zh) 2007-02-28
US20100094010A1 (en) 2010-04-15
US7626020B2 (en) 2009-12-01
UY28754A1 (es) 2005-09-30
JP2007523906A (ja) 2007-08-23
CY1112555T1 (el) 2016-02-10
PL2135873T3 (pl) 2012-03-30
NO20064012L (no) 2006-11-06
ES2375201T3 (es) 2012-02-27
JP2012031174A (ja) 2012-02-16
GB0403744D0 (en) 2004-03-24
US20080161565A1 (en) 2008-07-03
CL2011003138A1 (es) 2012-06-22
EP2135873A2 (en) 2009-12-23

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