HRP20110453T1 - Sastav peleta lipoične kiseline - Google Patents

Sastav peleta lipoične kiseline Download PDF

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Publication number
HRP20110453T1
HRP20110453T1 HR20110453T HRP20110453T HRP20110453T1 HR P20110453 T1 HRP20110453 T1 HR P20110453T1 HR 20110453 T HR20110453 T HR 20110453T HR P20110453 T HRP20110453 T HR P20110453T HR P20110453 T1 HRP20110453 T1 HR P20110453T1
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Croatia
Prior art keywords
composition according
lipophilic medium
lipoic acid
lipophilic
active substance
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HR20110453T
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English (en)
Inventor
Magri' Paolo
Nardi Antonio
Salvi Annibale
Villani Flavio
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Laboratorio Chimico Internazionale S.P.A.
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Publication of HRP20110453T1 publication Critical patent/HRP20110453T1/hr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Sastav koji sadrži pelete lipoične kiseline, ili jednu od njezinih soli, naznačen time, da jest u barem jednom lipofilnom mediju. Patent sadrži još 22 patentna zahtjeva.

Claims (23)

1. Sastav koji sadrži pelete lipoične kiseline, ili jednu od njezinih soli, naznačen time, da jest u barem jednom lipofilnom mediju.
2. Sastav prema patentnom zahtjevu 1, naznačen time, da navedeni lipofilni medij jest farmaceutski prihvatljiva i/ili jestiva lipofilna komponenta, koja je inertna ili ima blagotvorna svojstva na ljudski ili životinjski organizam.
3. Sastav prema patentnom zahtjevu 2, naznačen time, da navedeni lipofilni medij ima antioksidativna svojstva.
4. Sastav prema patentnim zahtjevima od 1 do 3, naznačen time, da navedeni lipofilni medij sadrži EPA i DHA.
5. Sastav prema patentnim zahtjevima od 1 do 3, naznačen time, da se navedeni lipofilni medij odabire između ribljeg ulja ili ulja jetre bakalara.
6. Sastav prema patentnom zahtjevu 5, naznačen time, da se navedeni lipofilni medij odabire između ribljeg ulja ili ulja jetre bakalara u pročišćenom obliku i obogaćenom u odnosu na Omega 3.
7. Sastav prema patentnom zahtjevu 6, naznačen time, da se navedeni lipofilni medij odabire između ribljeg ulja i ulja jetre bakalara u pročišćenom obliku i obogaćenom u odnosu na EPA i DHA.
8. Sastav prema patentnim zahtjevima od 1 do 7, naznačen time, da navedeni lipofilni medij sadrži gama-linolensku kiselinu.
9. Sastav prema patentnim zahtjevima 1 ili 2, naznačen time, da sadrži i druge aktivne tvari.
10. Sastav prema patentnim zahtjevima od 1 do 9, naznačen time, da sadrži i benfotiamin.
11. Sastav prema bilo kojem od prethodnih patentnih zahtjeva, naznačen time, da je u obliku jedinica doziranja.
12. Sastav prema patentnom zahtjevu 11, naznačen time, da je u obliku želatinskih kapsula.
13. Sastav prema bilo kojem od patentnih zahtjeva 11 ili 12, naznačen time, da sadrži od 10 do 1000 mg lipoične kiseline.
14. Sastav prema patentnom zahtjevu 13, naznačen time, da sadrži od 100 do 800 mg lipoične kiseline.
15. Sastav prema bilo kojem od patentnih zahtjeva od 11 do 14, naznačen time, da sadrži između 100 i 1000 mg ribljeg ulja ili ulja jetre bakalara u pročišćenom obliku.
16. Sastav prema bilo kojem od patentnih zahtjeva od 10 do 13, naznačen time, da sadrži između 100 i 3000 mg smjese EPA i DHA.
17. Sastav prema bilo kojem od patentnih zahtjeva od 11 do 14, naznačen time, da sadrži 300 do 1000 mg gama-linolenske kiseline.
18. Sastav prema bilo kojem od patentnih zahtjeva od 1 do 17, naznačen time, da sadrži i aktivnu tvar odabranu između gabapentina, pregabalina, olmesartan kaptoprila, interferona, akamprosata i megestrola.
19. Sastav prema bilo kojem od patentnih zahtjeva od 1 do 17, naznačen time, da sadrži i aktivnu tvar s antioksidativnim djelovanjem.
20. Uporaba sastava prema bilo kojem od prethodnih patentnih zahtjeva, naznačena time, da jest za pripremu lijeka za liječenje oksidativnog stresa.
21. Jedinica doziranja, naznačena time, da sadrži sastav prema bilo kojem od patentnih zahtjeva od 1 do 19.
22. Sastav prema patentnom zahtjevu 9, naznačen time, da navedena druga aktivna tvar jest antagonist angiotenzina II.
23. Sastav prema patentnom zahtjevu 9, naznačen time, da navedena druga aktivna tvar jest ACE inhibitor.
HR20110453T 2007-10-23 2011-06-16 Sastav peleta lipoične kiseline HRP20110453T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002051A ITMI20072051A1 (it) 2007-10-23 2007-10-23 Composizione a base di pellet di acido lipoico
PCT/IB2008/002835 WO2009053824A1 (en) 2007-10-23 2008-10-23 Lipoic acid pellet composition

Publications (1)

Publication Number Publication Date
HRP20110453T1 true HRP20110453T1 (hr) 2011-07-31

Family

ID=40313864

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110453T HRP20110453T1 (hr) 2007-10-23 2011-06-16 Sastav peleta lipoične kiseline

Country Status (27)

Country Link
US (1) US9820948B2 (hr)
EP (1) EP2217220B1 (hr)
JP (1) JP5626890B2 (hr)
KR (1) KR101599078B1 (hr)
CN (1) CN101861144B (hr)
AT (1) ATE506053T1 (hr)
AU (1) AU2008315667B2 (hr)
BR (1) BRPI0816587A2 (hr)
CA (1) CA2703152C (hr)
CY (1) CY1112122T1 (hr)
DE (1) DE602008006454D1 (hr)
DK (1) DK2217220T3 (hr)
ES (1) ES2363880T3 (hr)
HR (1) HRP20110453T1 (hr)
IL (1) IL205211A (hr)
IT (1) ITMI20072051A1 (hr)
MX (1) MX2010004481A (hr)
NZ (1) NZ584884A (hr)
PL (1) PL2217220T3 (hr)
PT (1) PT2217220E (hr)
RS (1) RS51712B (hr)
RU (1) RU2501558C2 (hr)
SI (1) SI2217220T1 (hr)
TN (1) TN2010000163A1 (hr)
UA (1) UA100394C2 (hr)
WO (1) WO2009053824A1 (hr)
ZA (1) ZA201002777B (hr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0818473D0 (en) 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
WO2011099031A1 (en) 2010-02-11 2011-08-18 Zota Health Care Limited Active antioxidants for all age group
GB201006200D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
US20130045273A1 (en) * 2011-08-19 2013-02-21 John Cuomo Methods for using nutritional supplements containing lipoic acids and sulfur containing compounds
CA2965671A1 (en) * 2014-10-24 2016-04-28 Robert Shorr Methods and compositions for the treatment of pre-diabetes, diabetes and metabolic syndrome
MX2016017321A (es) * 2016-12-14 2018-08-20 Cidat S A De C V Combinacicones y metodos para el tratamiento de dolor neuropatico.
CN106729725A (zh) * 2017-03-21 2017-05-31 北京百慧生化制药有限责任公司 硫辛酸作为抗氧化剂在多烯酸乙酯制剂或蛹油α‑亚麻酸乙酯制剂中的应用
IT202200007232A1 (it) * 2022-04-12 2023-10-12 Uriach Italy S R L Composizione comprendente acido lipoico, vitamina d e glutatione, suoi usi, e relative composizioni farmaceutiche e nutraceutiche
WO2023199241A1 (en) * 2022-04-12 2023-10-19 URIACH ITALY S.r.l. Composition comprising lipoic acid, vitamin d and glutathione, uses thereof, and pharmaceutical and nutraceutical compositions thereof

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WO2001021208A1 (en) * 1999-09-23 2001-03-29 Juvenon Corporation Nutritional supplement for increased energy and stamina
WO2002036202A2 (en) * 2000-11-02 2002-05-10 Nutrition 21, Inc. Methods and compositions for the improvement of insulin sensitivity, reduction of hyperglycemia, and reduction of hypercholesterolemia with chromium complexes and alpha lipoic acid
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JP5157001B2 (ja) * 2005-04-30 2013-03-06 ビーエイチエヌ株式会社 安定化α−リポ酸組成物及びその利用
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JP5085329B2 (ja) * 2005-09-12 2012-11-28 協和発酵バイオ株式会社 α−リポ酸含有組成物
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ITMI20061024A1 (it) * 2006-05-25 2007-11-26 Eurand Pharmaceuticals Ltd Pellet a base di acido lipoico

Also Published As

Publication number Publication date
UA100394C2 (en) 2012-12-25
KR20100089848A (ko) 2010-08-12
RU2501558C2 (ru) 2013-12-20
CY1112122T1 (el) 2015-11-04
BRPI0816587A2 (pt) 2015-03-03
JP5626890B2 (ja) 2014-11-19
RU2010120706A (ru) 2011-11-27
US20110129442A1 (en) 2011-06-02
KR101599078B1 (ko) 2016-03-02
TN2010000163A1 (en) 2011-11-11
PL2217220T3 (pl) 2011-09-30
IL205211A (en) 2013-01-31
JP2011500784A (ja) 2011-01-06
AU2008315667B2 (en) 2013-02-28
EP2217220B1 (en) 2011-04-20
CN101861144A (zh) 2010-10-13
EP2217220A1 (en) 2010-08-18
PT2217220E (pt) 2011-07-13
CA2703152C (en) 2016-02-23
ES2363880T3 (es) 2011-08-18
SI2217220T1 (sl) 2011-06-30
IL205211A0 (en) 2010-12-30
DK2217220T3 (da) 2011-08-01
ZA201002777B (en) 2011-06-29
CN101861144B (zh) 2013-03-13
AU2008315667A1 (en) 2009-04-30
ATE506053T1 (de) 2011-05-15
RS51712B (en) 2011-10-31
NZ584884A (en) 2011-11-25
DE602008006454D1 (de) 2011-06-01
CA2703152A1 (en) 2009-04-30
MX2010004481A (es) 2010-08-02
WO2009053824A1 (en) 2009-04-30
US9820948B2 (en) 2017-11-21
ITMI20072051A1 (it) 2009-04-24

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