HRP20100314T1 - Cjepivo protiv nipah virusa - Google Patents
Cjepivo protiv nipah virusa Download PDFInfo
- Publication number
- HRP20100314T1 HRP20100314T1 HR20100314T HRP20100314T HRP20100314T1 HR P20100314 T1 HRP20100314 T1 HR P20100314T1 HR 20100314 T HR20100314 T HR 20100314T HR P20100314 T HRP20100314 T HR P20100314T HR P20100314 T1 HRP20100314 T1 HR P20100314T1
- Authority
- HR
- Croatia
- Prior art keywords
- vector
- expression
- expression vector
- nipah virus
- pox
- Prior art date
Links
- 241000526636 Nipah henipavirus Species 0.000 title claims abstract 7
- 229960005486 vaccine Drugs 0.000 title 1
- 239000013604 expression vector Substances 0.000 claims abstract 11
- 239000013598 vector Substances 0.000 claims abstract 9
- 241000271566 Aves Species 0.000 claims abstract 7
- 102000003886 Glycoproteins Human genes 0.000 claims abstract 6
- 108090000288 Glycoproteins Proteins 0.000 claims abstract 6
- 102000040430 polynucleotide Human genes 0.000 claims abstract 2
- 108091033319 polynucleotide Proteins 0.000 claims abstract 2
- 239000002157 polynucleotide Substances 0.000 claims abstract 2
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 2
- 230000002238 attenuated effect Effects 0.000 claims 1
- 229940023860 canarypox virus HIV vaccine Drugs 0.000 claims 1
- 238000004321 preservation Methods 0.000 claims 1
- 238000001890 transfection Methods 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18211—Henipavirus, e.g. hendra virus
- C12N2760/18222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18211—Henipavirus, e.g. hendra virus
- C12N2760/18234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Ekspresioni ptičiji pox vektor, naznačen time što sadrži polinukleotid koji kodira glikoprotein Nipah virusa, gdje je ptičiji pox ekspresioni vektor canarypox vektor. Patent sadrži još 9 patentnih zahtjeva.
Claims (10)
1. Ekspresioni ptičiji pox vektor, naznačen time što sadrži polinukleotid koji kodira glikoprotein Nipah virusa, gdje je ptičiji pox ekspresioni vektor canarypox vektor.
2. Ekspresioni ptičiji pox vektor prema patentnom zahtjevu 1, naznačen time što je glikoprotein Nipah virusa vezujući (G) protein.
3. Ekspresioni ptičiji pox vektor prema patentnom zahtjevu 1, naznačen time što je glikoprotein Nipah virusa fuzijski (F) protein.
4. Ekspresioni ptičiji pox vektor prema patentnom zahtjevu 1, naznačen time što je glikoprotein Nipah virusa vezujući (G) protein i fuzijski (F) protein.
5. Ekspresioni ptičiji pox vektor prema bilo kojem od patentnih zahtjeva 1 to 4, naznačen time što je ptičiji pox ekspresioni vektor oslabljeni ptičji pox ekspresioni vektor.
6. Canarypox vektor prema bilo kojem od patentnih zahtjeva 1 do 5, naznačen time što je canarypox vektor ALVAC.
7. Ekspresioni vektor prema patentnom zahtjevu 1, naznačen time što je ekspresioni vektor vCP2199.
8. Ekspresioni vektor prema patentnom zahtjevu 1, naznačen time što je ekspresioni vektor vCP2208.
9. Formulacija za primjenu i ekspresiju glikoproteina Nipah virusa, naznačena time što formulacija sadrži vektor prema bilo kojem od patentnih zahtjeva 1 do 8 i farmaceutski ili veterinarski prihvatljiv nosač, razblaživač ili inertni punitelj.
10. Formulacija prema patentnom zahtjevu 9, naznačena time što nosač, razblaživač ili inertni punitelj olakšava transfekciju i/ili poboljšava očuvanje vektora.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67458305P | 2005-04-25 | 2005-04-25 | |
PCT/US2006/014134 WO2006115843A2 (en) | 2005-04-25 | 2006-04-14 | Nipah virus vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20100314T1 true HRP20100314T1 (hr) | 2010-08-31 |
Family
ID=37027869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20100314T HRP20100314T1 (hr) | 2005-04-25 | 2010-05-31 | Cjepivo protiv nipah virusa |
Country Status (15)
Country | Link |
---|---|
US (2) | US7803612B2 (hr) |
EP (2) | EP2198881A1 (hr) |
CN (1) | CN101208104B (hr) |
AT (1) | ATE461710T1 (hr) |
CA (1) | CA2605629C (hr) |
DE (1) | DE602006013117D1 (hr) |
DK (1) | DK1881845T3 (hr) |
ES (1) | ES2343270T3 (hr) |
HK (1) | HK1120730A1 (hr) |
HR (1) | HRP20100314T1 (hr) |
PL (1) | PL1881845T3 (hr) |
PT (1) | PT1881845E (hr) |
RS (1) | RS51324B (hr) |
SI (1) | SI1881845T1 (hr) |
WO (1) | WO2006115843A2 (hr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2684562A1 (de) * | 2008-08-08 | 2014-01-15 | Basf Se | Wirkstoffhaltige Fasernflächengebilde auf Basis von Biopolymeren, ihre Anwendungen und Verfahren zu ihrer Herstellung |
US20120263751A1 (en) * | 2009-11-20 | 2012-10-18 | Arigen Pharmaceuticals, Inc. | Recombinant Measles Virus Useful as a Bivalent Vaccine Against Measles and Nipah Infections |
CA2836098C (en) * | 2011-05-13 | 2022-06-21 | Zoetis Llc | Hendra and nipah virus g glycoprotein immunogenic compositions |
US20120301479A1 (en) * | 2011-05-27 | 2012-11-29 | Jean-Christophe Audonnet | Hendra virus recombinant compositions and uses thereof |
JP6260972B2 (ja) | 2012-02-14 | 2018-01-17 | メリアル インコーポレイテッド | 狂犬病タンパク質及びox40タンパク質の両方を発現する組換えポックスウイルスベクター並びに前記ベクターから製造されるワクチン |
EP3971286A3 (en) | 2012-03-26 | 2022-04-20 | The Regents of the University of California | Nipah virus envelope pseudotyped lentiviruses and methods of use |
JP6246199B2 (ja) * | 2012-07-02 | 2017-12-13 | ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | パラミクソウイルスおよび使用方法 |
US9549976B1 (en) * | 2012-11-16 | 2017-01-24 | Stc.Unm | Affinity selection of Nipah and Hendra virus-related vaccine candidates from a complex random peptide library displayed on bacteriophage virus-like particles |
WO2014189654A1 (en) * | 2013-05-23 | 2014-11-27 | Thomas Jefferson University | Co-immunization with attenuated rabies virus and non-rabies antigen |
CA2955124C (en) * | 2014-07-18 | 2024-01-02 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Peptides including a binding domain of the viral phosphoprotein (p) subunit to the viral rna free nucleoprotein (n0) |
EP3215188A1 (en) | 2014-11-03 | 2017-09-13 | Merial, Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
EP3235908A1 (en) | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
US11524066B2 (en) * | 2016-12-23 | 2022-12-13 | CureVac SE | Henipavirus vaccine |
BR112020011962A2 (pt) * | 2017-12-20 | 2020-11-17 | Zoetis Services Llc | vacinas contra infecção de vírus hendra e nipah |
JP2021514196A (ja) | 2018-02-23 | 2021-06-10 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | 外因性ネコパラミクソウイルス遺伝子を発現する組換えウイルスベクター系およびそれらから製作されるワクチン |
US11890339B2 (en) | 2018-08-03 | 2024-02-06 | The United States of Americam as represented by the Secretary, Department of Health and Human Services | Nipah virus immunogens and their use |
CN112888457A (zh) * | 2018-08-21 | 2021-06-01 | 威斯塔解剖学和生物学研究所 | 抗尼帕病毒的疫苗及其使用方法 |
KR20240028975A (ko) | 2021-04-08 | 2024-03-05 | 사나 바이오테크놀로지, 인크. | Cd8-특이적 항체 구조체들 및 이의 조성물 |
WO2022232218A1 (en) * | 2021-04-27 | 2022-11-03 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Recombinant cedar virus chimeras |
WO2023049794A1 (en) * | 2021-09-24 | 2023-03-30 | Board Of Regents, The University Of Texas System | Rapid acting vaccine against nipah virus |
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-
2006
- 2006-04-14 PL PL06750224T patent/PL1881845T3/pl unknown
- 2006-04-14 RS RSP-2010/0240A patent/RS51324B/sr unknown
- 2006-04-14 PT PT06750224T patent/PT1881845E/pt unknown
- 2006-04-14 DK DK06750224.5T patent/DK1881845T3/da active
- 2006-04-14 AT AT06750224T patent/ATE461710T1/de active
- 2006-04-14 EP EP10152096A patent/EP2198881A1/en not_active Ceased
- 2006-04-14 DE DE602006013117T patent/DE602006013117D1/de active Active
- 2006-04-14 WO PCT/US2006/014134 patent/WO2006115843A2/en active Application Filing
- 2006-04-14 US US11/404,534 patent/US7803612B2/en active Active
- 2006-04-14 ES ES06750224T patent/ES2343270T3/es active Active
- 2006-04-14 CA CA2605629A patent/CA2605629C/en active Active
- 2006-04-14 EP EP06750224A patent/EP1881845B1/en active Active
- 2006-04-14 SI SI200630655T patent/SI1881845T1/sl unknown
- 2006-04-14 CN CN2006800227184A patent/CN101208104B/zh active Active
-
2008
- 2008-11-13 HK HK08112459.1A patent/HK1120730A1/xx unknown
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2010
- 2010-05-31 HR HR20100314T patent/HRP20100314T1/hr unknown
- 2010-07-20 US US12/839,556 patent/US8420389B2/en active Active
Also Published As
Publication number | Publication date |
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RS51324B (sr) | 2010-12-31 |
US20070031455A1 (en) | 2007-02-08 |
CA2605629C (en) | 2012-06-26 |
US20100278862A1 (en) | 2010-11-04 |
EP2198881A1 (en) | 2010-06-23 |
EP1881845B1 (en) | 2010-03-24 |
HK1120730A1 (en) | 2009-04-09 |
DK1881845T3 (da) | 2010-06-07 |
ATE461710T1 (de) | 2010-04-15 |
CN101208104B (zh) | 2012-10-31 |
WO2006115843A3 (en) | 2008-01-24 |
PL1881845T3 (pl) | 2010-08-31 |
US8420389B2 (en) | 2013-04-16 |
DE602006013117D1 (de) | 2010-05-06 |
WO2006115843A2 (en) | 2006-11-02 |
ES2343270T3 (es) | 2010-07-27 |
EP1881845A2 (en) | 2008-01-30 |
CN101208104A (zh) | 2008-06-25 |
CA2605629A1 (en) | 2006-11-02 |
PT1881845E (pt) | 2010-05-31 |
US7803612B2 (en) | 2010-09-28 |
SI1881845T1 (sl) | 2010-06-30 |
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