HRP20090434T1 - Sastavi kontroliranog otpuštanja za interferon koji se temelji na pegt/pbt blok kopolimerima - Google Patents
Sastavi kontroliranog otpuštanja za interferon koji se temelji na pegt/pbt blok kopolimerima Download PDFInfo
- Publication number
- HRP20090434T1 HRP20090434T1 HR20090434T HRP20090434T HRP20090434T1 HR P20090434 T1 HRP20090434 T1 HR P20090434T1 HR 20090434 T HR20090434 T HR 20090434T HR P20090434 T HRP20090434 T HR P20090434T HR P20090434 T1 HRP20090434 T1 HR P20090434T1
- Authority
- HR
- Croatia
- Prior art keywords
- block copolymers
- composition
- pegt
- poly
- controlled release
- Prior art date
Links
- 229920001400 block copolymer Polymers 0.000 title claims abstract 5
- 102000014150 Interferons Human genes 0.000 title claims abstract 4
- 108010050904 Interferons Proteins 0.000 title claims abstract 4
- 229940079322 interferon Drugs 0.000 title claims 2
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000013270 controlled release Methods 0.000 title abstract 2
- -1 poly(ethylene glycol) Polymers 0.000 claims abstract 8
- 238000000034 method Methods 0.000 claims abstract 6
- 229920001707 polybutylene terephthalate Polymers 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 229940047124 interferons Drugs 0.000 claims abstract 3
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract 2
- KKEYFWRCBNTPAC-UHFFFAOYSA-L terephthalate(2-) Chemical compound [O-]C(=O)C1=CC=C(C([O-])=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-L 0.000 claims abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 4
- 239000000839 emulsion Substances 0.000 claims 4
- 239000008346 aqueous phase Substances 0.000 claims 3
- 239000012071 phase Substances 0.000 claims 3
- 239000003960 organic solvent Substances 0.000 claims 2
- 239000002357 osmotic agent Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 150000003839 salts Chemical group 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 1
- 230000001804 emulsifying effect Effects 0.000 claims 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05075043A EP1679065A1 (en) | 2005-01-07 | 2005-01-07 | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
| PCT/NL2006/000006 WO2006085747A1 (en) | 2005-01-07 | 2006-01-06 | Controlled release compositions for interferon based on pegt/pbt block copolymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090434T1 true HRP20090434T1 (hr) | 2009-09-30 |
Family
ID=34937981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090434T HRP20090434T1 (hr) | 2005-01-07 | 2009-08-11 | Sastavi kontroliranog otpuštanja za interferon koji se temelji na pegt/pbt blok kopolimerima |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US7736674B2 (ru) |
| EP (4) | EP1679065A1 (ru) |
| JP (2) | JP2008526837A (ru) |
| KR (2) | KR101354521B1 (ru) |
| CN (2) | CN101137349B (ru) |
| AT (1) | ATE431134T1 (ru) |
| AU (2) | AU2006213168B2 (ru) |
| BR (1) | BRPI0606514A2 (ru) |
| CA (1) | CA2594434A1 (ru) |
| CY (1) | CY1109297T1 (ru) |
| DE (1) | DE602006006797D1 (ru) |
| DK (1) | DK1843749T3 (ru) |
| ES (1) | ES2327267T3 (ru) |
| HK (1) | HK1152644A1 (ru) |
| HR (1) | HRP20090434T1 (ru) |
| IL (2) | IL184431A (ru) |
| MX (1) | MX2007008293A (ru) |
| PL (1) | PL1843749T3 (ru) |
| PT (1) | PT1843749E (ru) |
| RS (1) | RS51129B (ru) |
| RU (2) | RU2409348C2 (ru) |
| SG (1) | SG158856A1 (ru) |
| SI (1) | SI1843749T1 (ru) |
| WO (1) | WO2006085747A1 (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
| CA2694440A1 (en) * | 2007-07-25 | 2009-01-29 | Biolex Therapeutics, Inc. | Controlled release interferon drug products and treatment of hcv infection using same |
| EP2055299A1 (en) | 2007-10-23 | 2009-05-06 | Koninklijke Philips Electronics N.V. | Methods for preparing polymer microparticles |
| US8313676B2 (en) | 2007-10-23 | 2012-11-20 | Koninklijke Philips Electronics N.V. | Methods for preparing polymer microparticles |
| JP2011526619A (ja) * | 2008-06-30 | 2011-10-13 | サイレンシード リミテッド | 局所ドラッグデリバリーシステム、その方法、および、その組成物 |
| JP2012519666A (ja) | 2009-03-05 | 2012-08-30 | アセンディス ファーマ エーエス | インターフェロンアルファ担体プロドラッグ |
| KR20140022025A (ko) * | 2011-03-25 | 2014-02-21 | 셀렉타 바이오사이언시즈, 인크. | 삼투적 매개 방출 합성 나노담체 |
| DK2583680T1 (da) | 2011-10-21 | 2015-01-19 | Abbvie Inc | Mono (PSI-7977) eller kombinationsbehandling af DAA til anvendelse ved behandling af HCV |
| CN104383541A (zh) | 2011-10-21 | 2015-03-04 | 艾伯维公司 | 用于治疗hcv的包含至少两种直接抗病毒剂和利巴韦林但无干扰素的方法 |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US11229600B2 (en) | 2014-09-24 | 2022-01-25 | Vital Beverages Global Inc. | Compositions and methods for selective GI tract delivery |
| CA3022119A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
| BR112021023788A2 (pt) | 2019-07-12 | 2022-02-08 | Basf Se | Processo para produzir micropartículas, composição de micropartículas, produto, e, uso da composição |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL280825A (ru) * | 1962-07-11 | |||
| US5372808A (en) * | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| US5192743A (en) * | 1992-01-16 | 1993-03-09 | Genentech, Inc. | Reconstitutable lyophilized protein formulation |
| EP0637229B1 (en) | 1992-04-24 | 2002-11-20 | Osteotech, Inc., | Devices for preventing tissue adhesion |
| US5711968A (en) * | 1994-07-25 | 1998-01-27 | Alkermes Controlled Therapeutics, Inc. | Composition and method for the controlled release of metal cation-stabilized interferon |
| EP0582459B1 (en) | 1992-08-07 | 1998-01-07 | Takeda Chemical Industries, Ltd. | Production of microcapsules of water-soluble drugs |
| US5643605A (en) | 1993-10-25 | 1997-07-01 | Genentech, Inc. | Methods and compositions for microencapsulation of adjuvants |
| US6117455A (en) | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
| US5612052A (en) | 1995-04-13 | 1997-03-18 | Poly-Med, Inc. | Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| AU722042B2 (en) | 1995-11-30 | 2000-07-20 | Board Of Regents, The University Of Texas System | Methods and compositions for the diagnosis and treatment of cancer |
| US5792477A (en) | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
| US5980948A (en) * | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
| JP4153563B2 (ja) | 1997-02-27 | 2008-09-24 | ノバルティス アーゲー | 医薬組成物 |
| ATE252375T1 (de) * | 1997-04-17 | 2003-11-15 | Amgen Inc | Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung |
| TW577759B (en) | 1997-04-18 | 2004-03-01 | Ipsen Pharma Biotech | Sustained release compositions in the form of microcapsules or implants and the process for their preparation |
| US6531154B1 (en) | 1997-06-10 | 2003-03-11 | Brown University Research Foundation | Modulated release from biocompatible polymers |
| JP2001521006A (ja) * | 1997-10-24 | 2001-11-06 | イーライ・リリー・アンド・カンパニー | 不溶性インシュリン組成物 |
| US6270802B1 (en) | 1998-10-28 | 2001-08-07 | Oakwood Laboratories L.L.C. | Method and apparatus for formulating microspheres and microcapsules |
| US6194006B1 (en) | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
| CA2360232A1 (en) * | 1999-01-12 | 2000-07-20 | Tamio Mizukami | Telomerase inhibitors |
| US6204308B1 (en) | 1999-03-01 | 2001-03-20 | Novartis Ag | Organic compounds |
| US20030206928A1 (en) * | 1999-04-07 | 2003-11-06 | Pertti Tormala | Bioactive, bioabsorbable surgical polyethylene glycol and polybutylene terephtalate copolymer composites and devices |
| US6291013B1 (en) | 1999-05-03 | 2001-09-18 | Southern Biosystems, Inc. | Emulsion-based processes for making microparticles |
| SK342002A3 (en) | 1999-07-15 | 2002-05-09 | Takeda Chemical Industries Ltd | Sustained release compositions, process for producing the same and use thereof |
| EP1090928B1 (en) | 1999-09-30 | 2004-05-26 | Chienna B.V. | Polymers loaded with bioactive agents |
| US6465425B1 (en) * | 2000-02-10 | 2002-10-15 | Alkermes Controlled Therapeutics, Inc. | Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins |
| US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
| US6479065B2 (en) | 2000-08-10 | 2002-11-12 | Alkermes Controlled Therapeutics, Inc. | Process for the preparation of polymer-based sustained release compositions |
| US6471995B1 (en) | 2000-09-27 | 2002-10-29 | Alkermes Controlled Therapeutics, Inc. Ii | Apparatus and method for preparing microparticles using liquid-liquid extraction |
| JP4557409B2 (ja) * | 2000-11-13 | 2010-10-06 | 日東電工株式会社 | 多孔質ポリイミドの製造方法及び多孔質ポリイミド |
| CZ20031559A3 (cs) | 2000-12-13 | 2004-03-17 | Merckle Gmbh | Mikročástice se zlepšeným profilem uvolňování a způsob jejich výroby |
| US8637077B2 (en) | 2000-12-28 | 2014-01-28 | Takeda Pharmaceutical Company Limited | Sustained-release preparation |
| RU2191012C1 (ru) | 2001-06-20 | 2002-10-20 | Научно-исследовательский испытательный центр (медико-биологической защиты) Государственного научно-исследовательского испытательного института военной медицины МО РФ | Глазные капли для лечения эндотелиально-эпителиальной дистрофии роговицы |
| RU2279292C2 (ru) | 2001-10-24 | 2006-07-10 | Пари Гмбх | Набор для приготовления фармацевтической композиции |
| JP2005510521A (ja) * | 2001-11-12 | 2005-04-21 | アルカーメス コントロールド セラピューティクス，インコーポレイテッド | 生体適合性ポリマーブレンドおよびその使用 |
| TWI252111B (en) | 2001-12-14 | 2006-04-01 | Solvay Pharm Gmbh | Matrix film tablet with controlled release of a natural mixture of conjugated estrogens |
| WO2003055470A1 (fr) | 2001-12-26 | 2003-07-10 | Takeda Chemical Industries, Ltd. | Nouvelle microsphere et son procede de production |
| DK1532985T3 (en) | 2002-06-25 | 2016-12-05 | Takeda Pharmaceuticals Co | PROCEDURE FOR PREPARING A COMPOSITION WITH LONG-TERM RELEASE |
| JP5165239B2 (ja) | 2003-07-15 | 2013-03-21 | ピーアール ファーマシューティカルズ， インコーポレイテッド | 制御放出処方物の調製のための方法 |
| ES2375802T3 (es) | 2004-04-15 | 2012-03-06 | Alkermes Pharma Ireland Limited | Dispositivo de liberación sostenida a base de pol�?mero. |
| EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
-
2005
- 2005-01-07 EP EP05075043A patent/EP1679065A1/en not_active Withdrawn
-
2006
- 2006-01-06 AU AU2006213168A patent/AU2006213168B2/en not_active Ceased
- 2006-01-06 JP JP2007550316A patent/JP2008526837A/ja active Pending
- 2006-01-06 PT PT06700417T patent/PT1843749E/pt unknown
- 2006-01-06 DK DK06700417T patent/DK1843749T3/da active
- 2006-01-06 RS RSP-2009/0358A patent/RS51129B/sr unknown
- 2006-01-06 CN CN200680007430XA patent/CN101137349B/zh not_active Expired - Fee Related
- 2006-01-06 ES ES06700417T patent/ES2327267T3/es active Active
- 2006-01-06 EP EP06700417A patent/EP1843749B1/en active Active
- 2006-01-06 CN CN200910207704A patent/CN101791396A/zh active Pending
- 2006-01-06 SI SI200630366T patent/SI1843749T1/sl unknown
- 2006-01-06 BR BRPI0606514-7A patent/BRPI0606514A2/pt not_active IP Right Cessation
- 2006-01-06 DE DE602006006797T patent/DE602006006797D1/de active Active
- 2006-01-06 MX MX2007008293A patent/MX2007008293A/es active IP Right Grant
- 2006-01-06 KR KR1020107020687A patent/KR101354521B1/ko not_active IP Right Cessation
- 2006-01-06 EP EP10182460A patent/EP2266535B1/en active Active
- 2006-01-06 PL PL06700417T patent/PL1843749T3/pl unknown
- 2006-01-06 CA CA002594434A patent/CA2594434A1/en not_active Abandoned
- 2006-01-06 RU RU2007130090/15A patent/RU2409348C2/ru not_active IP Right Cessation
- 2006-01-06 WO PCT/NL2006/000006 patent/WO2006085747A1/en active Application Filing
- 2006-01-06 AT AT06700417T patent/ATE431134T1/de active
- 2006-01-06 KR KR1020077018068A patent/KR20070118225A/ko not_active Application Discontinuation
- 2006-01-06 SG SG201000063-6A patent/SG158856A1/en unknown
- 2006-01-06 EP EP07120539A patent/EP1886668B1/en active Active
-
2007
- 2007-07-05 IL IL184431A patent/IL184431A/en not_active IP Right Cessation
- 2007-07-06 US US11/774,107 patent/US7736674B2/en not_active Expired - Fee Related
-
2009
- 2009-05-15 US US12/466,430 patent/US7867518B2/en not_active Expired - Fee Related
- 2009-08-10 CY CY20091100844T patent/CY1109297T1/el unknown
- 2009-08-11 HR HR20090434T patent/HRP20090434T1/hr unknown
- 2009-11-25 US US12/625,929 patent/US8163307B2/en not_active Expired - Fee Related
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2010
- 2010-09-14 JP JP2010205413A patent/JP4887542B2/ja not_active Expired - Fee Related
- 2010-09-15 IL IL208175A patent/IL208175A0/en unknown
- 2010-09-20 RU RU2010138739/15A patent/RU2010138739A/ru unknown
- 2010-09-24 AU AU2010224413A patent/AU2010224413B2/en not_active Ceased
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2011
- 2011-06-28 HK HK11106616.8A patent/HK1152644A1/xx not_active IP Right Cessation
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