ATE252375T1 - Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung - Google Patents

Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung

Info

Publication number
ATE252375T1
ATE252375T1 AT98918424T AT98918424T ATE252375T1 AT E252375 T1 ATE252375 T1 AT E252375T1 AT 98918424 T AT98918424 T AT 98918424T AT 98918424 T AT98918424 T AT 98918424T AT E252375 T1 ATE252375 T1 AT E252375T1
Authority
AT
Austria
Prior art keywords
delayed release
biodegradable microparticles
relates
present
polymeric microparticles
Prior art date
Application number
AT98918424T
Other languages
English (en)
Inventor
Subodh Shah
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/843,975 external-priority patent/US6020004A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE252375T1 publication Critical patent/ATE252375T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT98918424T 1997-04-17 1998-04-17 Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung ATE252375T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/843,975 US6020004A (en) 1997-04-17 1997-04-17 Biodegradable microparticles for the sustained delivery of therapeutic drugs
US6166598A 1998-04-16 1998-04-16
PCT/US1998/007856 WO1998046212A1 (en) 1997-04-17 1998-04-17 Biodegradable microparticles for the sustained delivery of therapeutic drugs

Publications (1)

Publication Number Publication Date
ATE252375T1 true ATE252375T1 (de) 2003-11-15

Family

ID=26741350

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918424T ATE252375T1 (de) 1997-04-17 1998-04-17 Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung

Country Status (10)

Country Link
EP (1) EP0975334B1 (de)
JP (1) JP2002514215A (de)
AT (1) ATE252375T1 (de)
AU (1) AU7134898A (de)
CA (1) CA2287534C (de)
DE (1) DE69819145T2 (de)
DK (1) DK0975334T3 (de)
ES (1) ES2205481T3 (de)
PT (1) PT975334E (de)
WO (1) WO1998046212A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69434258T2 (de) 1993-11-19 2006-01-19 Janssen Pharmaceutica N.V. Mikroverkapselte 1,2-benzazole
US6291013B1 (en) 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles
AU1226901A (en) * 1999-10-22 2001-05-08 Amgen, Inc. Biodegradable microparticles with novel erythropoietin stimulating protein
US7029700B2 (en) 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
JP2003519651A (ja) * 2000-01-14 2003-06-24 ブラウン ユニバーシティ リサーチ ファウンデーション 微紛化凍結乾燥粒子
WO2002036169A2 (en) * 2000-10-31 2002-05-10 Pr Pharmaceuticals, Inc. Methods and compositions for enhanced delivery of bioactive molecules
EP1829529A1 (de) * 2002-05-03 2007-09-05 PR Pharmaceuticals, Inc. Zusammensetzungen zur kontrollierten Freisetzung von Estradiolmetaboliten
JP2005525403A (ja) * 2002-05-03 2005-08-25 ピーアール ファーマシューティカルズ， インコーポレイテッド エストラジオール代謝産物の徐放性組成物
JP2006522816A (ja) 2003-04-11 2006-10-05 ピーアール ファーマシューティカルズ， インコーポレイテッド 部位特異的タンパク質結合体を調製する方法
WO2005112885A2 (en) 2004-05-12 2005-12-01 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
DK1765294T3 (da) 2004-05-12 2008-11-10 Baxter Int Nukleinsyremikrokugler samt deres fremstilling og afgivelse
EP1679065A1 (de) * 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Zubereitung mit kontrollierter Freisetzung von Interferon auf PEGT/PBT-Block-Copolymer-Basis
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
JP5118139B2 (ja) 2006-08-04 2013-01-16 バクスター・インターナショナル・インコーポレイテッド 新規発症自己免疫性糖尿病を予防および／または逆転させるためのマイクロスフィアに基づく組成物
WO2008131129A2 (en) 2007-04-17 2008-10-30 Baxter International Inc. Nucleic acid microparticles for pulmonary delivery
US20110059167A1 (en) * 2008-05-06 2011-03-10 Glaxo Group Limited Encapsulation of biologically active agents
JP5552118B2 (ja) * 2008-06-09 2014-07-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入用の新規な埋込み粒子
KR20100037389A (ko) * 2008-10-01 2010-04-09 연세대학교 산학협력단 다중 약물방출조절이 가능한 솔리드 마이크로구조체 및 이의 제조방법
US10363281B2 (en) 2016-07-18 2019-07-30 Tissuegen, Inc. Methods and compositions for maintaining the conformation and structural integrity of biomolecules

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058915A (ja) * 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd 薬物含有脂質小胞体製剤
JP2653255B2 (ja) * 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
AU4459196A (en) * 1995-01-23 1996-08-14 Takeda Chemical Industries Ltd. Sustained-release preparation and use

Also Published As

Publication number Publication date
EP0975334B1 (de) 2003-10-22
JP2002514215A (ja) 2002-05-14
AU7134898A (en) 1998-11-11
DE69819145D1 (de) 2003-11-27
CA2287534C (en) 2004-12-28
CA2287534A1 (en) 1998-10-22
HK1022265A1 (en) 2000-08-04
DE69819145T2 (de) 2004-08-19
PT975334E (pt) 2004-03-31
EP0975334A1 (de) 2000-02-02
ES2205481T3 (es) 2004-05-01
DK0975334T3 (da) 2004-01-19
WO1998046212A1 (en) 1998-10-22

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