DE69819145D1 - Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung - Google Patents

Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung

Info

Publication number
DE69819145D1
DE69819145D1 DE69819145T DE69819145T DE69819145D1 DE 69819145 D1 DE69819145 D1 DE 69819145D1 DE 69819145 T DE69819145 T DE 69819145T DE 69819145 T DE69819145 T DE 69819145T DE 69819145 D1 DE69819145 D1 DE 69819145D1
Authority
DE
Germany
Prior art keywords
bio
active substance
substance release
delayed active
degradable microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69819145T
Other languages
English (en)
Other versions
DE69819145T2 (de
Inventor
Subodh Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/843,975 external-priority patent/US6020004A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of DE69819145D1 publication Critical patent/DE69819145D1/de
Application granted granted Critical
Publication of DE69819145T2 publication Critical patent/DE69819145T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69819145T 1997-04-17 1998-04-17 Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung Expired - Fee Related DE69819145T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/843,975 US6020004A (en) 1997-04-17 1997-04-17 Biodegradable microparticles for the sustained delivery of therapeutic drugs
US843975 1997-04-17
US6166598A 1998-04-16 1998-04-16
US61665 1998-04-16
PCT/US1998/007856 WO1998046212A1 (en) 1997-04-17 1998-04-17 Biodegradable microparticles for the sustained delivery of therapeutic drugs

Publications (2)

Publication Number Publication Date
DE69819145D1 true DE69819145D1 (de) 2003-11-27
DE69819145T2 DE69819145T2 (de) 2004-08-19

Family

ID=26741350

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69819145T Expired - Fee Related DE69819145T2 (de) 1997-04-17 1998-04-17 Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung

Country Status (11)

Country Link
EP (1) EP0975334B1 (de)
JP (1) JP2002514215A (de)
AT (1) ATE252375T1 (de)
AU (1) AU7134898A (de)
CA (1) CA2287534C (de)
DE (1) DE69819145T2 (de)
DK (1) DK0975334T3 (de)
ES (1) ES2205481T3 (de)
HK (1) HK1022265A1 (de)
PT (1) PT975334E (de)
WO (1) WO1998046212A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100354270B1 (ko) 1993-11-19 2003-02-11 알커메스 컨트롤드 테라포이틱스 인코퍼레이티드 Ii 마이크로캡슐화된3-피페리디닐-치환된1,2-벤즈이속사졸및1,2-벤즈이소티아졸
US6291013B1 (en) 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles
AU1226901A (en) * 1999-10-22 2001-05-08 Amgen, Inc. Biodegradable microparticles with novel erythropoietin stimulating protein
US7029700B2 (en) 2000-01-14 2006-04-18 Brown University Research Foundation Micronized freeze-dried particles
DE60141680D1 (de) * 2000-01-14 2010-05-12 Univ Brown Res Found Verfahren zur herstellung von mikronisierte gefriergetrocknete partikeln
ATE537845T1 (de) * 2000-10-31 2012-01-15 Pr Pharmaceuticals Inc Verfahren zur herstellung von formulierungen zur verbesserten abgabe von bioaktiven molekülen
US20060083778A1 (en) * 2002-05-03 2006-04-20 Dean Allison Controlled release compositions of estradiol metabolites
EP1829529A1 (de) * 2002-05-03 2007-09-05 PR Pharmaceuticals, Inc. Zusammensetzungen zur kontrollierten Freisetzung von Estradiolmetaboliten
DK2599502T3 (en) 2003-04-11 2017-04-18 Antriabio Inc Process for Preparation of Site-Specific Protein Conjugates
DK1758558T3 (da) 2004-05-12 2014-01-20 Baxter Int Oligonukleotidholdige mikrokugler samt deres anvendelse til fremstilling af et medikament til behandling af diabetes type 1
ES2313350T3 (es) 2004-05-12 2009-03-01 Baxter International Inc. Microesferas de acido nucleico, produccion y suministro de las mismas.
EP1679065A1 (de) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Zubereitung mit kontrollierter Freisetzung von Interferon auf PEGT/PBT-Block-Copolymer-Basis
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AU2007281737B2 (en) 2006-08-04 2013-09-19 Baxter Healthcare S.A. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
AU2008242842B2 (en) 2007-04-17 2014-06-05 Baxter Healthcare Sa Nucleic acid microparticles for pulmonary delivery
JP2011519893A (ja) * 2008-05-06 2011-07-14 グラクソ グループ リミテッド 生物活性薬の封入
EP2299990A1 (de) * 2008-06-09 2011-03-30 Boehringer Ingelheim International GmbH Neue einbettungspartikel für die inhalation
KR20100037389A (ko) * 2008-10-01 2010-04-09 연세대학교 산학협력단 다중 약물방출조절이 가능한 솔리드 마이크로구조체 및 이의 제조방법
EP3484450A4 (de) 2016-07-18 2020-04-01 Tissuegen, Inc. Verfahren und zusammensetzungen zur aufrechterhaltung der konformation und strukturellen integrität von biomolekülen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058915A (ja) * 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd 薬物含有脂質小胞体製剤
JP2653255B2 (ja) * 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
AU4459196A (en) * 1995-01-23 1996-08-14 Takeda Chemical Industries Ltd. Sustained-release preparation and use

Also Published As

Publication number Publication date
CA2287534C (en) 2004-12-28
EP0975334A1 (de) 2000-02-02
CA2287534A1 (en) 1998-10-22
EP0975334B1 (de) 2003-10-22
DK0975334T3 (da) 2004-01-19
WO1998046212A1 (en) 1998-10-22
ATE252375T1 (de) 2003-11-15
HK1022265A1 (en) 2000-08-04
ES2205481T3 (es) 2004-05-01
DE69819145T2 (de) 2004-08-19
JP2002514215A (ja) 2002-05-14
AU7134898A (en) 1998-11-11
PT975334E (pt) 2004-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee