HRP20090124T3 - Taste-masked formulation comprising clarithromycin - Google Patents
Taste-masked formulation comprising clarithromycinInfo
- Publication number
- HRP20090124T3 HRP20090124T3 HR20090124T HRP20090124T HRP20090124T3 HR P20090124 T3 HRP20090124 T3 HR P20090124T3 HR 20090124 T HR20090124 T HR 20090124T HR P20090124 T HRP20090124 T HR P20090124T HR P20090124 T3 HRP20090124 T3 HR P20090124T3
- Authority
- HR
- Croatia
- Prior art keywords
- clarithromycin
- taste
- micropellets
- polymer
- masked formulation
- Prior art date
Links
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 2
- 229960002626 clarithromycin Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 229920001688 coating polymer Polymers 0.000 abstract 2
- 239000002702 enteric coating Substances 0.000 abstract 2
- 238000009505 enteric coating Methods 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/688,551 US20050084540A1 (en) | 2003-10-17 | 2003-10-17 | Taste masking antibiotic composition |
| US10/768,562 US8168228B2 (en) | 2003-10-17 | 2004-01-30 | Antibiotic clarithromycin micropellet compositions |
| PCT/EP2004/011653 WO2005039536A1 (en) | 2003-10-17 | 2004-10-15 | Antibiotic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090124T3 true HRP20090124T3 (en) | 2009-04-30 |
Family
ID=34527177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090124T HRP20090124T3 (en) | 2003-10-17 | 2009-02-27 | Taste-masked formulation comprising clarithromycin |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8168228B2 (zh) |
| EP (1) | EP1680088B1 (zh) |
| JP (1) | JP2007508351A (zh) |
| CN (1) | CN1893927A (zh) |
| AR (1) | AR046113A1 (zh) |
| AT (1) | ATE415948T1 (zh) |
| AU (1) | AU2004283463B2 (zh) |
| BR (1) | BRPI0415450A (zh) |
| CA (1) | CA2542238A1 (zh) |
| DE (1) | DE602004018175D1 (zh) |
| DK (1) | DK1680088T3 (zh) |
| ES (1) | ES2317061T3 (zh) |
| HR (1) | HRP20090124T3 (zh) |
| PE (1) | PE20050441A1 (zh) |
| PL (1) | PL1680088T3 (zh) |
| PT (1) | PT1680088E (zh) |
| RU (1) | RU2376980C2 (zh) |
| SI (1) | SI1680088T1 (zh) |
| WO (1) | WO2005039536A1 (zh) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2891459B1 (fr) * | 2005-09-30 | 2007-12-28 | Flamel Technologies Sa | Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant |
| JP2013515490A (ja) * | 2009-12-23 | 2013-05-09 | ヴァックスジーン コーポレーション | 組み換え型乳酸連鎖球菌のミニカプセルの経口投与による免疫保護 |
| WO2011099932A1 (en) * | 2010-02-09 | 2011-08-18 | Agency For Science, Technology And Research | Smart polymers functionalized hollow silica vesicles |
| EP2386297A1 (en) * | 2010-04-28 | 2011-11-16 | Roquette Frères | Indigestible polymer: starch acetate -based film coatings for colon targeting |
| US8828426B2 (en) | 2011-06-07 | 2014-09-09 | Zx Pharma, Llc | Multiparticulate L-carnitine compositions and related methods |
| RU2649806C2 (ru) * | 2011-06-17 | 2018-04-04 | Эвоник Рем ГмбХ | Желудочно-резистентная фармацевтическая или нутрицевтическая композиция с устойчивостью к воздействию этанола |
| MX2011007675A (es) * | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| CN107125440A (zh) * | 2016-02-29 | 2017-09-05 | 湖南晶天科技实业有限公司 | 一种饲料添加剂肠溶包衣单宁酸及其制备方法以及一种饲料 |
| CN107960589A (zh) * | 2016-10-20 | 2018-04-27 | 湖南晶天科技实业有限公司 | 一种抗菌添加剂壳寡糖醛席夫碱和应用 |
| CN107960533A (zh) * | 2016-10-20 | 2018-04-27 | 湖南晶天科技实业有限公司 | 一种氨基酸醛席夫碱饲料添加剂以及一种饲料 |
| CN110075085A (zh) * | 2019-05-17 | 2019-08-02 | 南京望知星医药科技有限公司 | 一种罗红霉素微囊及其制备方法 |
| CN113116859B (zh) * | 2021-04-12 | 2022-08-30 | 海南普利制药股份有限公司 | 阿奇霉素丸芯包衣制剂 |
| CN113777329B (zh) * | 2021-09-16 | 2023-07-18 | 何秋富 | 一种视黄醇结合蛋白测定试剂盒及其制备方法 |
| WO2024043260A1 (en) * | 2022-08-24 | 2024-02-29 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising centanafadine |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3099711A (en) * | 1961-06-02 | 1963-07-30 | Data Presentations Inc | Printing device |
| DE3583799D1 (de) * | 1985-01-11 | 1991-09-19 | Abbott Lab Ltd | Feste zubereitung mit langsamer freisetzung. |
| US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
| NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
| US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
| JPH05255120A (ja) * | 1992-03-12 | 1993-10-05 | Taisho Pharmaceut Co Ltd | 苦み隠蔽製剤 |
| TW271400B (zh) * | 1992-07-30 | 1996-03-01 | Pfizer | |
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
| US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| SE9700885D0 (sv) * | 1997-03-12 | 1997-03-12 | Astra Ab | New pharmaceutical formulation |
| US6010718A (en) * | 1997-04-11 | 2000-01-04 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
| US6221402B1 (en) * | 1997-11-20 | 2001-04-24 | Pfizer Inc. | Rapidly releasing and taste-masking pharmaceutical dosage form |
| UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| JP2000103730A (ja) * | 1998-07-31 | 2000-04-11 | Otsuka Pharmaceut Co Ltd | 服用感が改善された医薬組成物 |
| US6096341A (en) * | 1998-10-30 | 2000-08-01 | Pharma Pass Llc | Delayed release tablet of bupropion hydrochloride |
| US6740341B1 (en) * | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
| IN191239B (zh) * | 1999-06-11 | 2003-10-11 | Ranbaxy Lab Ltd | |
| US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
| AU6381201A (en) | 2000-03-28 | 2001-10-08 | Biochemie Gmbh | Granulated particles with masked taste |
| IN192748B (zh) | 2000-08-29 | 2004-05-15 | Ranbaxy Lab Ltd | |
| JP3211824B1 (ja) * | 2000-10-26 | 2001-09-25 | 味の素株式会社 | 分岐鎖アミノ酸含有医薬用顆粒製剤とその製造方法 |
| ES2195727B1 (es) * | 2001-07-05 | 2005-03-01 | Ercros Industrial, S.A. | Un procedimiento para la obtencion de claritromicina. |
| WO2003020242A1 (en) | 2001-08-29 | 2003-03-13 | Srl Technologies, Inc. | Sustained release preparations |
| US6673369B2 (en) | 2001-08-29 | 2004-01-06 | Ranbaxy Laboratories Limited | Controlled release formulation |
| US6642276B2 (en) * | 2001-10-01 | 2003-11-04 | M/S Ind-Swift Limited | Controlled release macrolide pharmaceutical formulations |
| KR20050009983A (ko) * | 2002-03-22 | 2005-01-26 | 시락 아게 | 트라마돌의 서방성 제제 |
| PT1578350E (pt) * | 2002-03-26 | 2009-08-27 | Euro Celtique Sa | Composições revestidas com geles de libertação constante |
| EP1492504A2 (en) | 2002-04-03 | 2005-01-05 | Ranbaxy Laboratories, Ltd. | Taste masked compositions of erythromycin a and derivatives thereof |
| AU2003214506A1 (en) | 2002-04-03 | 2003-10-13 | Ranbaxy Laboratories Limited | Clarithromycin formulations having improved bioavailability |
| WO2003097102A1 (fr) * | 2002-05-22 | 2003-11-27 | Shionogi & Co., Ltd. | Preparation pharmaceutique dans laquelle la propriete de dissolution d'un medicament faiblement soluble dans l'eau est amelioree |
-
2004
- 2004-01-30 US US10/768,562 patent/US8168228B2/en not_active Expired - Fee Related
- 2004-10-14 AR ARP040103729A patent/AR046113A1/es unknown
- 2004-10-15 PE PE2004001001A patent/PE20050441A1/es not_active Application Discontinuation
- 2004-10-15 CN CNA2004800303808A patent/CN1893927A/zh active Pending
- 2004-10-15 DE DE602004018175T patent/DE602004018175D1/de active Active
- 2004-10-15 AT AT04790492T patent/ATE415948T1/de active
- 2004-10-15 WO PCT/EP2004/011653 patent/WO2005039536A1/en active Application Filing
- 2004-10-15 RU RU2006116622/15A patent/RU2376980C2/ru active
- 2004-10-15 AU AU2004283463A patent/AU2004283463B2/en not_active Ceased
- 2004-10-15 EP EP04790492A patent/EP1680088B1/en active Active
- 2004-10-15 JP JP2006534711A patent/JP2007508351A/ja active Pending
- 2004-10-15 PL PL04790492T patent/PL1680088T3/pl unknown
- 2004-10-15 CA CA002542238A patent/CA2542238A1/en not_active Abandoned
- 2004-10-15 SI SI200431050T patent/SI1680088T1/sl unknown
- 2004-10-15 PT PT04790492T patent/PT1680088E/pt unknown
- 2004-10-15 DK DK04790492T patent/DK1680088T3/da active
- 2004-10-15 BR BRPI0415450-9A patent/BRPI0415450A/pt not_active IP Right Cessation
- 2004-10-15 US US10/575,691 patent/US20070134344A1/en not_active Abandoned
- 2004-10-15 ES ES04790492T patent/ES2317061T3/es active Active
-
2009
- 2009-02-27 HR HR20090124T patent/HRP20090124T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2376980C2 (ru) | 2009-12-27 |
| PT1680088E (pt) | 2009-01-30 |
| US20070134344A1 (en) | 2007-06-14 |
| RU2006116622A (ru) | 2007-12-10 |
| US20050084541A1 (en) | 2005-04-21 |
| ATE415948T1 (de) | 2008-12-15 |
| ES2317061T3 (es) | 2009-04-16 |
| AR046113A1 (es) | 2005-11-23 |
| PL1680088T3 (pl) | 2009-06-30 |
| SI1680088T1 (sl) | 2009-08-31 |
| CN1893927A (zh) | 2007-01-10 |
| WO2005039536A1 (en) | 2005-05-06 |
| CA2542238A1 (en) | 2005-05-06 |
| JP2007508351A (ja) | 2007-04-05 |
| PE20050441A1 (es) | 2005-08-02 |
| AU2004283463A1 (en) | 2005-05-06 |
| DK1680088T3 (da) | 2009-03-23 |
| BRPI0415450A (pt) | 2006-12-19 |
| US8168228B2 (en) | 2012-05-01 |
| AU2004283463B2 (en) | 2007-12-20 |
| DE602004018175D1 (de) | 2009-01-15 |
| EP1680088A1 (en) | 2006-07-19 |
| EP1680088B1 (en) | 2008-12-03 |
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