HRP20090124T3 - Taste-masked formulation comprising clarithromycin - Google Patents
Taste-masked formulation comprising clarithromycinInfo
- Publication number
- HRP20090124T3 HRP20090124T3 HR20090124T HRP20090124T HRP20090124T3 HR P20090124 T3 HRP20090124 T3 HR P20090124T3 HR 20090124 T HR20090124 T HR 20090124T HR P20090124 T HRP20090124 T HR P20090124T HR P20090124 T3 HRP20090124 T3 HR P20090124T3
- Authority
- HR
- Croatia
- Prior art keywords
- clarithromycin
- taste
- micropellets
- polymer
- masked formulation
- Prior art date
Links
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 2
- 229960002626 clarithromycin Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 229920001688 coating polymer Polymers 0.000 abstract 2
- 239000002702 enteric coating Substances 0.000 abstract 2
- 238000009505 enteric coating Methods 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/688,551 US20050084540A1 (en) | 2003-10-17 | 2003-10-17 | Taste masking antibiotic composition |
| US10/768,562 US8168228B2 (en) | 2003-10-17 | 2004-01-30 | Antibiotic clarithromycin micropellet compositions |
| PCT/EP2004/011653 WO2005039536A1 (en) | 2003-10-17 | 2004-10-15 | Antibiotic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090124T3 true HRP20090124T3 (en) | 2009-04-30 |
Family
ID=34527177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090124T HRP20090124T3 (en) | 2003-10-17 | 2009-02-27 | Taste-masked formulation comprising clarithromycin |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8168228B2 (xx) |
| EP (1) | EP1680088B1 (xx) |
| JP (1) | JP2007508351A (xx) |
| CN (1) | CN1893927A (xx) |
| AR (1) | AR046113A1 (xx) |
| AT (1) | ATE415948T1 (xx) |
| AU (1) | AU2004283463B2 (xx) |
| BR (1) | BRPI0415450A (xx) |
| CA (1) | CA2542238A1 (xx) |
| DE (1) | DE602004018175D1 (xx) |
| DK (1) | DK1680088T3 (xx) |
| ES (1) | ES2317061T3 (xx) |
| HR (1) | HRP20090124T3 (xx) |
| PE (1) | PE20050441A1 (xx) |
| PL (1) | PL1680088T3 (xx) |
| PT (1) | PT1680088E (xx) |
| RU (1) | RU2376980C2 (xx) |
| SI (1) | SI1680088T1 (xx) |
| WO (1) | WO2005039536A1 (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2891459B1 (fr) * | 2005-09-30 | 2007-12-28 | Flamel Technologies Sa | Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant |
| WO2011079282A1 (en) * | 2009-12-23 | 2011-06-30 | Vaxgene Corporation | Immunoprotection by oral administration of recombinant lactococcus lactis mini-capsules |
| US20130034609A1 (en) * | 2010-02-09 | 2013-02-07 | Agency For Science, Technology And Research | Smart polymers functionalized hollow silica vesicles |
| EP2386297A1 (en) * | 2010-04-28 | 2011-11-16 | Roquette Frères | Indigestible polymer: starch acetate -based film coatings for colon targeting |
| US8828426B2 (en) * | 2011-06-07 | 2014-09-09 | Zx Pharma, Llc | Multiparticulate L-carnitine compositions and related methods |
| US9775815B2 (en) * | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
| MX2011007675A (es) * | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| CN107125440A (zh) * | 2016-02-29 | 2017-09-05 | 湖南晶天科技实业有限公司 | 一种饲料添加剂肠溶包衣单宁酸及其制备方法以及一种饲料 |
| CN107960533A (zh) * | 2016-10-20 | 2018-04-27 | 湖南晶天科技实业有限公司 | 一种氨基酸醛席夫碱饲料添加剂以及一种饲料 |
| CN107960589A (zh) * | 2016-10-20 | 2018-04-27 | 湖南晶天科技实业有限公司 | 一种抗菌添加剂壳寡糖醛席夫碱和应用 |
| CN110075085A (zh) * | 2019-05-17 | 2019-08-02 | 南京望知星医药科技有限公司 | 一种罗红霉素微囊及其制备方法 |
| CN113116859B (zh) * | 2021-04-12 | 2022-08-30 | 海南普利制药股份有限公司 | 阿奇霉素丸芯包衣制剂 |
| CN113777329B (zh) * | 2021-09-16 | 2023-07-18 | 何秋富 | 一种视黄醇结合蛋白测定试剂盒及其制备方法 |
| WO2024043260A1 (en) * | 2022-08-24 | 2024-02-29 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising centanafadine |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3099711A (en) * | 1961-06-02 | 1963-07-30 | Data Presentations Inc | Printing device |
| EP0188040B1 (en) | 1985-01-11 | 1991-08-14 | Abbott Laboratories Limited | Slow release solid preparation |
| US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
| NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
| US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
| JPH05255120A (ja) * | 1992-03-12 | 1993-10-05 | Taisho Pharmaceut Co Ltd | 苦み隠蔽製剤 |
| TW271400B (xx) | 1992-07-30 | 1996-03-01 | Pfizer | |
| US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
| US5788987A (en) | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| SE9700885D0 (sv) * | 1997-03-12 | 1997-03-12 | Astra Ab | New pharmaceutical formulation |
| US6010718A (en) | 1997-04-11 | 2000-01-04 | Abbott Laboratories | Extended release formulations of erythromycin derivatives |
| US6221402B1 (en) * | 1997-11-20 | 2001-04-24 | Pfizer Inc. | Rapidly releasing and taste-masking pharmaceutical dosage form |
| UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| JP2000103730A (ja) * | 1998-07-31 | 2000-04-11 | Otsuka Pharmaceut Co Ltd | 服用感が改善された医薬組成物 |
| US6096341A (en) | 1998-10-30 | 2000-08-01 | Pharma Pass Llc | Delayed release tablet of bupropion hydrochloride |
| US6740341B1 (en) * | 1998-11-25 | 2004-05-25 | Cima Labs Inc. | Taste masking rapid release coating system |
| IN191239B (xx) | 1999-06-11 | 2003-10-11 | Ranbaxy Lab Ltd | |
| US6451345B1 (en) | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
| MXPA02009587A (es) | 2000-03-28 | 2003-05-14 | Biochemie Gmbh | Particulas granuladas con sabor enmascarado. |
| IN192748B (xx) | 2000-08-29 | 2004-05-15 | Ranbaxy Lab Ltd | |
| JP3211824B1 (ja) * | 2000-10-26 | 2001-09-25 | 味の素株式会社 | 分岐鎖アミノ酸含有医薬用顆粒製剤とその製造方法 |
| ES2195727B1 (es) | 2001-07-05 | 2005-03-01 | Ercros Industrial, S.A. | Un procedimiento para la obtencion de claritromicina. |
| US6673369B2 (en) | 2001-08-29 | 2004-01-06 | Ranbaxy Laboratories Limited | Controlled release formulation |
| EP1429728A1 (en) | 2001-08-29 | 2004-06-23 | SRL Technologies, Inc. | Sustained release preparations |
| CA2405918A1 (en) | 2001-10-01 | 2003-04-01 | Ind-Swift Limited | Controlled release macrolide pharmaceutical formulations |
| RU2336864C2 (ru) * | 2002-03-22 | 2008-10-27 | Цилаг Аг | Лекарственные формы трамадола замедленного высвобождения |
| ES2327034T3 (es) * | 2002-03-26 | 2009-10-23 | Euro-Celtique S.A. | Composiciones recubiertas con gel de liberacion sostenida. |
| WO2003082248A2 (en) | 2002-04-03 | 2003-10-09 | Ranbaxy Laboratories Limited | Taste masked compositions of erythromycin a and derivatives thereof |
| CN1652753A (zh) | 2002-04-03 | 2005-08-10 | 兰贝克赛实验室有限公司 | 具有改进的生物利用度的克拉霉素制剂 |
| JP4743684B2 (ja) * | 2002-05-22 | 2011-08-10 | 塩野義製薬株式会社 | 難水溶性薬物の溶出性を改善する方法 |
-
2004
- 2004-01-30 US US10/768,562 patent/US8168228B2/en not_active Expired - Fee Related
- 2004-10-14 AR ARP040103729A patent/AR046113A1/es unknown
- 2004-10-15 DE DE602004018175T patent/DE602004018175D1/de active Active
- 2004-10-15 CA CA002542238A patent/CA2542238A1/en not_active Abandoned
- 2004-10-15 CN CNA2004800303808A patent/CN1893927A/zh active Pending
- 2004-10-15 AT AT04790492T patent/ATE415948T1/de active
- 2004-10-15 PE PE2004001001A patent/PE20050441A1/es not_active Application Discontinuation
- 2004-10-15 BR BRPI0415450-9A patent/BRPI0415450A/pt not_active IP Right Cessation
- 2004-10-15 ES ES04790492T patent/ES2317061T3/es active Active
- 2004-10-15 PL PL04790492T patent/PL1680088T3/pl unknown
- 2004-10-15 DK DK04790492T patent/DK1680088T3/da active
- 2004-10-15 RU RU2006116622/15A patent/RU2376980C2/ru active
- 2004-10-15 US US10/575,691 patent/US20070134344A1/en not_active Abandoned
- 2004-10-15 WO PCT/EP2004/011653 patent/WO2005039536A1/en active Application Filing
- 2004-10-15 SI SI200431050T patent/SI1680088T1/sl unknown
- 2004-10-15 PT PT04790492T patent/PT1680088E/pt unknown
- 2004-10-15 JP JP2006534711A patent/JP2007508351A/ja active Pending
- 2004-10-15 AU AU2004283463A patent/AU2004283463B2/en not_active Ceased
- 2004-10-15 EP EP04790492A patent/EP1680088B1/en active Active
-
2009
- 2009-02-27 HR HR20090124T patent/HRP20090124T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0415450A (pt) | 2006-12-19 |
| EP1680088A1 (en) | 2006-07-19 |
| PT1680088E (pt) | 2009-01-30 |
| AR046113A1 (es) | 2005-11-23 |
| ATE415948T1 (de) | 2008-12-15 |
| PL1680088T3 (pl) | 2009-06-30 |
| AU2004283463A1 (en) | 2005-05-06 |
| US20050084541A1 (en) | 2005-04-21 |
| SI1680088T1 (sl) | 2009-08-31 |
| CA2542238A1 (en) | 2005-05-06 |
| PE20050441A1 (es) | 2005-08-02 |
| RU2376980C2 (ru) | 2009-12-27 |
| US8168228B2 (en) | 2012-05-01 |
| US20070134344A1 (en) | 2007-06-14 |
| DE602004018175D1 (de) | 2009-01-15 |
| WO2005039536A1 (en) | 2005-05-06 |
| JP2007508351A (ja) | 2007-04-05 |
| ES2317061T3 (es) | 2009-04-16 |
| EP1680088B1 (en) | 2008-12-03 |
| RU2006116622A (ru) | 2007-12-10 |
| DK1680088T3 (da) | 2009-03-23 |
| AU2004283463B2 (en) | 2007-12-20 |
| CN1893927A (zh) | 2007-01-10 |
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