HRP20040753A2 - Pressurised metered dose inhalers containing solutions of beta-2 agonists - Google Patents

Pressurised metered dose inhalers containing solutions of beta-2 agonists

Info

Publication number
HRP20040753A2
HRP20040753A2 HRP20040753A HRP20040753A2 HR P20040753 A2 HRP20040753 A2 HR P20040753A2 HR P20040753 A HRP20040753 A HR P20040753A HR P20040753 A2 HRP20040753 A2 HR P20040753A2
Authority
HR
Croatia
Prior art keywords
agonists
beta
metered dose
containing solutions
dose inhalers
Prior art date
Application number
Other languages
English (en)
Inventor
Rebecca Jaine Davies
David Ganderton
David Andrew Lewis
Brian John Meakin
Tanya Kathleen Church
Gaetano Brambilla
Alessandra Ferraris
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27790093&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20040753(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP02004786A external-priority patent/EP1340492A1/fr
Priority claimed from EP02023589A external-priority patent/EP1415647A1/fr
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of HRP20040753A2 publication Critical patent/HRP20040753A2/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
HRP20040753 2002-03-01 2004-08-20 Pressurised metered dose inhalers containing solutions of beta-2 agonists HRP20040753A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02004786A EP1340492A1 (fr) 2002-03-01 2002-03-01 Formulations d'aérosol pour l'administration par voie pulmonaire de medicaments avec effet systémique
EP02023589A EP1415647A1 (fr) 2002-10-23 2002-10-23 Beta-2-agonistes à activité de longue durée dans une formulation ultrafine
PCT/EP2003/002004 WO2003074025A2 (fr) 2002-03-01 2003-02-27 Formulations hfa de beta 2-agonistes a action prolongee de derives de 2(1h)-qiunolinone

Publications (1)

Publication Number Publication Date
HRP20040753A2 true HRP20040753A2 (en) 2004-12-31

Family

ID=27790093

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20040753 HRP20040753A2 (en) 2002-03-01 2004-08-20 Pressurised metered dose inhalers containing solutions of beta-2 agonists
HRP20040752AA HRP20040752B1 (hr) 2002-03-01 2004-08-20 Superfina formulacija formoterola

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20040752AA HRP20040752B1 (hr) 2002-03-01 2004-08-20 Superfina formulacija formoterola

Country Status (36)

Country Link
US (4) US20050152846A1 (fr)
EP (6) EP3384931B1 (fr)
JP (3) JP2005523905A (fr)
KR (2) KR100947409B1 (fr)
CN (2) CN100398094C (fr)
AR (2) AR038644A1 (fr)
AT (1) ATE465712T1 (fr)
AU (2) AU2003222753B2 (fr)
BR (2) BRPI0308274B8 (fr)
CA (2) CA2477881C (fr)
CO (2) CO5611091A2 (fr)
CY (4) CY1111133T1 (fr)
DE (1) DE60332321D1 (fr)
DK (4) DK3494995T3 (fr)
EA (2) EA007735B1 (fr)
ES (4) ES2342463T3 (fr)
GE (2) GEP20063986B (fr)
HK (1) HK1079425A1 (fr)
HR (2) HRP20040753A2 (fr)
HU (3) HUE044926T2 (fr)
IL (3) IL163843A0 (fr)
LT (3) LT3536344T (fr)
MA (1) MA27175A1 (fr)
ME (3) MEP30108A (fr)
MX (2) MXPA04008372A (fr)
MY (2) MY143517A (fr)
NO (2) NO342575B1 (fr)
NZ (2) NZ535018A (fr)
PE (2) PE20030824A1 (fr)
PL (2) PL209212B1 (fr)
PT (4) PT3494995T (fr)
RS (2) RS52387B (fr)
SI (4) SI1480615T1 (fr)
TN (2) TNSN04149A1 (fr)
TW (2) TWI347197B (fr)
WO (2) WO2003074024A1 (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
AU2000250701B2 (en) * 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
US20040101483A1 (en) * 2001-03-30 2004-05-27 Rudi Muller-Walz Medical aerosol formulations
SI1273292T1 (en) * 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
EP1415647A1 (fr) * 2002-10-23 2004-05-06 CHIESI FARMACEUTICI S.p.A. Beta-2-agonistes à activité de longue durée dans une formulation ultrafine
EP1340492A1 (fr) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Formulations d'aérosol pour l'administration par voie pulmonaire de medicaments avec effet systémique
DK3494995T3 (da) * 2002-03-01 2020-03-23 Chiesi Farm Spa Superfin formoterolformulering
EP1452179A1 (fr) * 2003-02-27 2004-09-01 CHIESI FARMACEUTICI S.p.A. Nouveau combination d'un puissant agoniste beta 2 de longue duree et un corticosteroid
CA2534120C (fr) * 2003-07-31 2012-09-11 Boehringer Ingelheim International Gmbh Medicaments pour inhalation comportant un agent a activite anticholinergique et betamimetique
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
KR20070000476A (ko) * 2004-02-27 2007-01-02 키에시 파르마슈티시 엣스. 피. 에이. 압축화 계량된 도스흡입용 안정된 약제용액 제제
EP1595531A1 (fr) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Formulation d'une solution pharmaceutique stable pour aérosols doseurs sous pression
CN100457087C (zh) * 2004-02-27 2009-02-04 奇斯药制品公司 用于加压计量吸入器的稳定的药用溶液制剂
WO2005112902A2 (fr) * 2004-05-13 2005-12-01 Chiesi Farmaceutici S.P.A. Produits de formulation d'aerosol medicinale a stabilite chimique amelioree
BRPI0512878A (pt) * 2004-07-02 2008-04-15 Boehringer Ingelheim Int formulações de suspensão de aerossol, com tg 227 ea ou tg 134 a como agente propulsor
GB0420722D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
SG159550A1 (en) 2005-02-25 2010-03-30 Chiesi Farma Spa Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
EP1982709A1 (fr) 2007-04-19 2008-10-22 CHIESI FARMACEUTICI S.p.A. Utilisation d'une composition comportant du formotérol et du dipropionate de béclométhasone pour la prévention ou le traitement d'une condition aiguë de l'asthme
EP2100598A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100599A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
GB2461752B (en) * 2008-07-14 2013-04-17 Neo Inhalation Products Ltd Metered dose inhaler
CA2741078A1 (fr) * 2008-10-23 2010-04-29 Sunovion Pharmaceuticals Inc. Compositions d'arformoterol et de tiotropium et leurs procedes d'utilisation
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
CA2785317C (fr) 2009-12-23 2018-02-27 Chiesi Farmaceutici S.P.A. Preparation aerosol pour copd (bronchopneumopathie chronique obstructive)
CN102665679B (zh) 2009-12-23 2014-11-26 奇斯药制品公司 用于copd的联合治疗
EP2360147A1 (fr) * 2010-02-22 2011-08-24 CHIESI FARMACEUTICI S.p.A. Procédé de préparation de particules crystallines d'un sel de 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone (carmoterol)
NZ605920A (en) * 2010-07-16 2015-01-30 Cipla Ltd Pharmaceutical compositions comprising r (+) budesonide and one or more bronchodilators
TWI399202B (zh) 2011-03-17 2013-06-21 Intech Biopharm Ltd 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法
EP2510928A1 (fr) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
CN104797190B (zh) * 2012-11-15 2018-07-17 杰普呼吸技术公司 用于肺机能测量的装置和方法
RU2504402C1 (ru) * 2012-11-20 2014-01-20 Шолекс Девелопмент Гмбх Ингаляционный состав в форме аэрозоля для лечения бронхиальной астмы и хронической обструктивной болезни легких
CN106667973A (zh) * 2017-01-22 2017-05-17 西咸新区世云工研坊生物科技有限公司 一种用于防雾霾损伤的组合物及其制备方法和喷剂
AU2021213883A1 (en) 2020-01-28 2022-07-21 Chiesi Farmaceutici S.P.A. Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation
CN115087431A (zh) 2020-02-20 2022-09-20 奇斯药制品公司 包含缓冲药物制剂的加压定量吸入器
WO2023227783A1 (fr) 2022-05-27 2023-11-30 Chiesi Farmaceutici S.P.A. Formulation pharmaceutique pour aérosol-doseur sous pression

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361306A (en) * 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3622053A (en) * 1969-12-10 1971-11-23 Schering Corp Aerosol inhaler with flip-up nozzle
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4499108A (en) * 1983-06-08 1985-02-12 Schering Corporation Stable pleasant-tasting albuterol sulfate pharmaceutical formulations
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US4584320A (en) * 1985-01-03 1986-04-22 David Rubin Anti-asthmatic composition and method using 8,11,14,17-eicosatetraenoic acid
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
IT1244441B (it) * 1990-09-13 1994-07-15 Chiesi Farma Spa Dispositivo per l'inalazione boccale di farmaci aerosol
US6006745A (en) * 1990-12-21 1999-12-28 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US6299863B1 (en) * 1992-04-03 2001-10-09 Sepracor Inc. Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy
BR9206422A (pt) * 1991-08-29 1995-10-17 Christoph Klein Aparelho médico para a inalação de aerossóis dosados
DE4230876A1 (de) * 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
AU6048694A (en) * 1992-12-09 1994-07-04 Paul D. Jager Stabilized medicinal aerosol solution formulations
ZA939195B (en) * 1992-12-09 1995-06-08 Boehringer Ingelheim Pharma Stabilized medicinal aerosol solution formulations
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US5899201A (en) * 1993-05-26 1999-05-04 Minnesota Mining And Manufacturing Company Aerosol actuator
CA2178473C (fr) * 1993-12-20 2004-08-24 Tsi-Zong Tzou Compositions d'aerosols a base de flunisolide
US5508269A (en) * 1994-10-19 1996-04-16 Pathogenesis Corporation Aminoglycoside formulation for aerosolization
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
CN1217654C (zh) * 1995-04-14 2005-09-07 史密丝克莱恩比彻姆公司 舒喘宁的计定剂量吸入器
CN1113675C (zh) * 1995-04-14 2003-07-09 葛兰素惠尔康公司 丙酸福地卡松的计定剂量吸入器
US5637505A (en) * 1995-05-19 1997-06-10 Chiron Diagnostics Corporation Method to prepare dye-based reference material
CA2264524A1 (fr) * 1996-10-04 1998-04-09 Norihiro Shinkai Timbre percutane
US6040344A (en) * 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
US6413496B1 (en) * 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
JP2001511160A (ja) * 1997-02-05 2001-08-07 ヤゴ リサーチ アクチェンゲゼルシャフト 医学用エアゾール配合物
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5891419A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
US6188933B1 (en) * 1997-05-12 2001-02-13 Light & Sound Design Ltd. Electronically controlled stage lighting system
US20010031244A1 (en) * 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2326334A (en) 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
US6045784A (en) * 1998-05-07 2000-04-04 The Procter & Gamble Company Aerosol package compositions containing fluorinated hydrocarbon propellants
US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
DE59911149D1 (de) 1998-07-24 2004-12-30 Jago Res Ag Muttenz Medizinische aerosolformulierungen
NZ509489A (en) * 1998-08-04 2002-10-25 Jago Res A Medicinal aerosol formulations comprising cromoglycic acid and/or nedocromil
DE19847969A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Lagerfähig flüssige Formulierung mit Formoterol
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
SK284889B6 (sk) * 1998-11-13 2006-02-02 Jago Research Ag Použitie stearátu horečnatého v suchých práškových formuláciách na inhaláciu
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6290930B1 (en) * 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
US6352152B1 (en) * 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol
GB9904919D0 (en) * 1999-03-03 1999-04-28 Novartis Ag Organic compounds
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
ATE343374T1 (de) * 1999-09-11 2006-11-15 Glaxo Group Ltd Fluticasonpropionat arzneizubereitung
GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
US6578125B2 (en) 2000-02-14 2003-06-10 Sanyo Electric Co., Ltd. Memory access circuit and memory access control circuit
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
GB0008660D0 (en) * 2000-04-07 2000-05-31 Arakis Ltd The treatment of respiratory diseases
GB0009773D0 (en) 2000-04-19 2000-06-07 Univ Cardiff Particulate composition
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
AU2000250701B2 (en) * 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
EP1241113A1 (fr) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhalateur avec des moyens pour améliorer la stabilité chimique des solutions d'aerosol médicinales qu'il contient
SI1273292T1 (en) * 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
DK3494995T3 (da) * 2002-03-01 2020-03-23 Chiesi Farm Spa Superfin formoterolformulering
EP1340492A1 (fr) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Formulations d'aérosol pour l'administration par voie pulmonaire de medicaments avec effet systémique
EP1595531A1 (fr) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Formulation d'une solution pharmaceutique stable pour aérosols doseurs sous pression

Also Published As

Publication number Publication date
KR20040093080A (ko) 2004-11-04
TW200303767A (en) 2003-09-16
EP3494995A2 (fr) 2019-06-12
ME00077B (fr) 2010-06-10
PT3536344T (pt) 2020-03-26
KR100947409B1 (ko) 2010-03-12
PE20030824A1 (es) 2003-11-07
TNSN04147A1 (en) 2007-03-12
ES2745064T3 (es) 2020-02-27
SI3494995T1 (sl) 2020-08-31
KR20040093079A (ko) 2004-11-04
RS76604A (en) 2006-10-27
PT3384931T (pt) 2019-09-26
DK3536344T3 (da) 2020-03-16
DK3494995T3 (da) 2020-03-23
PL209212B1 (pl) 2011-08-31
US20090263488A1 (en) 2009-10-22
EA200401007A1 (ru) 2005-04-28
EP1480615A1 (fr) 2004-12-01
US20110061651A1 (en) 2011-03-17
NZ535017A (en) 2007-02-23
NO20043625L (no) 2004-09-29
MY137603A (en) 2009-02-27
HRP20040752A2 (en) 2004-12-31
EA008592B1 (ru) 2007-06-29
BR0308274A (pt) 2004-12-28
TWI347197B (en) 2011-08-21
IL163843A0 (en) 2005-12-18
JP2010215637A (ja) 2010-09-30
SI3536344T1 (sl) 2020-06-30
LT3384931T (lt) 2019-09-25
WO2003074025A3 (fr) 2003-12-24
GEP20063986B (en) 2006-12-11
JP2005523905A (ja) 2005-08-11
AR038644A1 (es) 2005-01-19
CA2477885C (fr) 2010-12-21
EP3494995A3 (fr) 2019-07-24
AU2003222753B2 (en) 2008-04-17
MY143517A (en) 2011-05-31
BR0308275A (pt) 2004-12-28
SI1480615T1 (sl) 2010-07-30
CA2477881C (fr) 2011-02-01
EA007735B1 (ru) 2006-12-29
CA2477881A1 (fr) 2003-09-12
RS52387B (en) 2013-02-28
EP1480617A2 (fr) 2004-12-01
NO20043626L (no) 2004-08-31
MXPA04008369A (es) 2004-11-26
EP2201964A2 (fr) 2010-06-30
EP3384931A1 (fr) 2018-10-10
CN100398094C (zh) 2008-07-02
CY1122851T1 (el) 2021-05-05
CN1638729A (zh) 2005-07-13
DK1480615T3 (da) 2010-07-12
AR038641A1 (es) 2005-01-19
MXPA04008372A (es) 2004-11-26
WO2003074025A2 (fr) 2003-09-12
CN1638730A (zh) 2005-07-13
PT1480615E (pt) 2010-06-16
DK3384931T3 (da) 2019-09-16
MA27175A1 (fr) 2005-01-03
AU2003210370B2 (en) 2007-08-30
CY1122027T1 (el) 2020-10-14
PE20030827A1 (es) 2003-11-06
PT3494995T (pt) 2020-03-30
ES2779273T3 (es) 2020-08-14
CY1111133T1 (el) 2015-06-11
SI3384931T1 (sl) 2019-11-29
IL163844A0 (en) 2005-12-18
CO5611091A2 (es) 2006-02-28
RS76704A (en) 2007-02-05
CA2477885A1 (fr) 2003-09-12
NO342575B1 (no) 2018-06-18
MEP30108A (en) 2010-06-10
HUE044926T2 (hu) 2019-11-28
US20050154013A1 (en) 2005-07-14
EP2201964B1 (fr) 2018-08-08
HRP20040752B1 (hr) 2012-10-31
MEP30208A (en) 2010-10-10
IL163843A (en) 2011-08-31
EP3384931B1 (fr) 2019-07-24
EA200401005A1 (ru) 2005-08-25
EP2201964A3 (fr) 2013-01-23
BRPI0308274B8 (pt) 2021-05-25
JP2005524664A (ja) 2005-08-18
TW200303752A (en) 2003-09-16
LT3494995T (lt) 2020-04-10
BRPI0308274B1 (pt) 2018-10-30
GEP20063876B (en) 2006-07-10
US20050152846A1 (en) 2005-07-14
WO2003074024A1 (fr) 2003-09-12
HUE048310T2 (hu) 2020-07-28
PL372173A1 (en) 2005-07-11
NZ535018A (en) 2007-02-23
ES2780127T3 (es) 2020-08-24
ES2342463T3 (es) 2010-07-07
HUE049426T2 (hu) 2020-09-28
EP1480615B1 (fr) 2010-04-28
PL372292A1 (en) 2005-07-11
AU2003210370C1 (en) 2008-03-13
KR100961603B1 (ko) 2010-06-04
EP3536344A1 (fr) 2019-09-11
DE60332321D1 (de) 2010-06-10
EP3494995B1 (fr) 2020-02-19
EP3536344B1 (fr) 2020-02-19
TNSN04149A1 (en) 2007-03-12
CO5611092A2 (es) 2006-02-28
AU2003222753A1 (en) 2003-09-16
ATE465712T1 (de) 2010-05-15
CY1122875T1 (el) 2021-05-05
AU2003210370A1 (en) 2003-09-16
LT3536344T (lt) 2020-04-10
HK1079425A1 (en) 2006-04-07
US8313732B2 (en) 2012-11-20

Similar Documents

Publication Publication Date Title
IL163844A0 (en) Pressurised metered dose inhalers containing solutions of beta-2 agonists
ZA200406918B (en) Pressurised metered dose inhalers containing solutions of beta-2 agonists
HUS1800032I1 (hu) Gyógyászati célú stabil aeroszol összetétel, inhalátor az aeroszol pontos adagolásához és eljárás ennek feltöltésére
PL369072A1 (en) Metered dose inhaler
IL179491A0 (en) Pressurised metered dose inhalers
AU2003286786A1 (en) Increased dosage metered dose inhaler
GB0328630D0 (en) Metered dose inhalation preparations
AU4417101A (en) Metered dose inhaler
AU2001256168A1 (en) Metered dose inhaler
AU4417001A (en) Metered dose inhaler
GB0020978D0 (en) Metered dose inhaler
GB0226274D0 (en) Metered dose inhalation preparations
GB0328629D0 (en) Metered dose inhalation preparations
AU2002236091A1 (en) Canisters for use in metered dose inhalers
HU0800754D0 (en) Ressurised metered dose inhalers
GB0018653D0 (en) Metered dose inhaler
GB0004761D0 (en) Metered dose inhaler
GB0018685D0 (en) Metered dose inhaler
GB0018684D0 (en) Metered dose inhaler
GB0018675D0 (en) Metered dose inhaler
GB0018674D0 (en) Metered dose inhaler
GB0018652D0 (en) Metered dose inhaler
GB0004763D0 (en) Metered dose inhaler
GB0018624D0 (en) Metered dose inhaler
GB0004798D0 (en) Metered dose inhaler

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20100205

Year of fee payment: 8

OBST Application withdrawn