HRP20040311A2 - Spiro-hydantoin compounds useful as anti-inflammatory agents - Google Patents
Spiro-hydantoin compounds useful as anti-inflammatory agents Download PDFInfo
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- HRP20040311A2 HRP20040311A2 HR20040311A HRP20040311A HRP20040311A2 HR P20040311 A2 HRP20040311 A2 HR P20040311A2 HR 20040311 A HR20040311 A HR 20040311A HR P20040311 A HRP20040311 A HR P20040311A HR P20040311 A2 HRP20040311 A2 HR P20040311A2
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- alkyl
- 4alkyl
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- heteroaryl
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- 229940121363 anti-inflammatory agent Drugs 0.000 title description 8
- 239000002260 anti-inflammatory agent Substances 0.000 title description 8
- QAHZIGHCEBUNGT-QMGFNSACSA-N (5r,6s,7s,8r,9r)-6,7,8-trihydroxy-9-(hydroxymethyl)-1,3-diazaspiro[4.5]decane-2,4-dione Chemical class O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)C[C@]11C(=O)NC(=O)N1 QAHZIGHCEBUNGT-QMGFNSACSA-N 0.000 title description 5
- 150000001875 compounds Chemical class 0.000 claims description 282
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- C—CHEMISTRY; METALLURGY
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- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- General Chemical & Material Sciences (AREA)
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- Rheumatology (AREA)
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- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US32636101P | 2001-10-01 | 2001-10-01 | |
US35411302P | 2002-02-04 | 2002-02-04 | |
US40025902P | 2002-08-01 | 2002-08-01 | |
PCT/US2002/031283 WO2003029245A1 (en) | 2001-10-01 | 2002-09-30 | Spiro-hydantoin compounds useful as anti-inflammatory agents |
Publications (1)
Publication Number | Publication Date |
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HRP20040311A2 true HRP20040311A2 (en) | 2005-02-28 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HR20040311A HRP20040311A2 (en) | 2001-10-01 | 2004-04-01 | Spiro-hydantoin compounds useful as anti-inflammatory agents |
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US (4) | US6977267B2 (es) |
EP (1) | EP1432700B1 (es) |
JP (1) | JP4394442B2 (es) |
KR (1) | KR20040041649A (es) |
CN (1) | CN1596253A (es) |
AR (1) | AR036663A1 (es) |
AT (1) | ATE447565T1 (es) |
BR (1) | BR0213025A (es) |
CA (1) | CA2462112A1 (es) |
DE (1) | DE60234264D1 (es) |
ES (1) | ES2339107T3 (es) |
GE (1) | GEP20063767B (es) |
HK (1) | HK1063467A1 (es) |
HR (1) | HRP20040311A2 (es) |
HU (1) | HUP0402338A3 (es) |
IL (1) | IL160990A0 (es) |
IS (1) | IS7197A (es) |
MX (1) | MXPA04002993A (es) |
NO (1) | NO20041339L (es) |
NZ (1) | NZ531870A (es) |
PE (1) | PE20030845A1 (es) |
PL (1) | PL369337A1 (es) |
RS (1) | RS26604A (es) |
WO (1) | WO2003029245A1 (es) |
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CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
US5346913A (en) * | 1992-05-26 | 1994-09-13 | Rohm And Haas Company | N-iodopropargyl hydantoin compounds, compositions, preparation, and use as antimicrobial agents |
FR2694290B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
TW521073B (en) * | 1994-01-05 | 2003-02-21 | Hoechst Marion Roussel Inc | New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them |
FR2741342B1 (fr) * | 1995-11-22 | 1998-02-06 | Roussel Uclaf | Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques |
CA2447475A1 (en) | 2001-05-25 | 2002-12-05 | Chu-Biao Xue | Hydantion derivatives as inhibitors of matrix metalloproteinases |
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2002
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- 2002-09-30 NZ NZ531870A patent/NZ531870A/en unknown
- 2002-09-30 CN CNA028238540A patent/CN1596253A/zh active Pending
- 2002-09-30 DE DE60234264T patent/DE60234264D1/de not_active Expired - Lifetime
- 2002-09-30 HU HU0402338A patent/HUP0402338A3/hu unknown
- 2002-09-30 KR KR10-2004-7004778A patent/KR20040041649A/ko not_active Application Discontinuation
- 2002-09-30 IL IL16099002A patent/IL160990A0/xx unknown
- 2002-09-30 EP EP02800414A patent/EP1432700B1/en not_active Expired - Lifetime
- 2002-09-30 BR BR0213025-4A patent/BR0213025A/pt not_active IP Right Cessation
- 2002-09-30 GE GE5595A patent/GEP20063767B/en unknown
- 2002-09-30 RS YU26604A patent/RS26604A/sr unknown
- 2002-09-30 WO PCT/US2002/031283 patent/WO2003029245A1/en active IP Right Grant
- 2002-09-30 ES ES02800414T patent/ES2339107T3/es not_active Expired - Lifetime
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2004
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- 2004-03-31 NO NO20041339A patent/NO20041339L/no not_active Application Discontinuation
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- 2004-05-24 US US10/852,576 patent/US7078420B2/en not_active Expired - Lifetime
- 2004-06-16 US US10/869,289 patent/US20040259897A1/en not_active Abandoned
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US20040009998A1 (en) | 2004-01-15 |
BR0213025A (pt) | 2004-10-05 |
RS26604A (en) | 2006-12-15 |
NO20041339D0 (no) | 2004-03-31 |
ES2339107T3 (es) | 2010-05-17 |
EP1432700A1 (en) | 2004-06-30 |
NO20041339L (no) | 2004-05-24 |
KR20040041649A (ko) | 2004-05-17 |
NZ531870A (en) | 2005-08-26 |
AR036663A1 (es) | 2004-09-22 |
JP4394442B2 (ja) | 2010-01-06 |
IL160990A0 (en) | 2004-08-31 |
EP1432700B1 (en) | 2009-11-04 |
JP2005510476A (ja) | 2005-04-21 |
US6977267B2 (en) | 2005-12-20 |
CN1596253A (zh) | 2005-03-16 |
US20050004153A1 (en) | 2005-01-06 |
ATE447565T1 (de) | 2009-11-15 |
US20040259897A1 (en) | 2004-12-23 |
US20040248920A1 (en) | 2004-12-09 |
DE60234264D1 (de) | 2009-12-17 |
IS7197A (is) | 2004-03-24 |
US7078420B2 (en) | 2006-07-18 |
EP1432700A4 (en) | 2004-12-22 |
WO2003029245A1 (en) | 2003-04-10 |
PE20030845A1 (es) | 2003-10-23 |
MXPA04002993A (es) | 2004-07-15 |
HUP0402338A3 (en) | 2008-10-28 |
PL369337A1 (en) | 2005-04-18 |
HUP0402338A2 (hu) | 2005-02-28 |
GEP20063767B (en) | 2006-03-10 |
CA2462112A1 (en) | 2003-04-10 |
HK1063467A1 (en) | 2004-12-31 |
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