HRP20030691A2 - Processes for the production of substituted 2-(2-pyridylmethyl)sulfinyl-benzimidazoles - Google Patents
Processes for the production of substituted 2-(2-pyridylmethyl)sulfinyl-benzimidazolesInfo
- Publication number
- HRP20030691A2 HRP20030691A2 HR20030691A HRP20030691A HRP20030691A2 HR P20030691 A2 HRP20030691 A2 HR P20030691A2 HR 20030691 A HR20030691 A HR 20030691A HR P20030691 A HRP20030691 A HR P20030691A HR P20030691 A2 HRP20030691 A2 HR P20030691A2
- Authority
- HR
- Croatia
- Prior art keywords
- benzimidazoles
- pyridylmethyl
- sulfinyl
- substituted
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26616201P | 2001-02-02 | 2001-02-02 | |
| PCT/US2002/003225 WO2002062786A1 (en) | 2001-02-02 | 2002-02-04 | Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20030691A2 true HRP20030691A2 (en) | 2005-04-30 |
Family
ID=23013433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20030691A HRP20030691A2 (en) | 2001-02-02 | 2002-02-04 | Processes for the production of substituted 2-(2-pyridylmethyl)sulfinyl-benzimidazoles |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US7129358B2 (cs) |
| EP (2) | EP1970374A1 (cs) |
| JP (1) | JP2004524303A (cs) |
| KR (1) | KR20040029966A (cs) |
| CN (3) | CN100347167C (cs) |
| CA (1) | CA2436467A1 (cs) |
| CZ (1) | CZ20032351A3 (cs) |
| DE (1) | DE02706135T1 (cs) |
| ES (1) | ES2209678T1 (cs) |
| HR (1) | HRP20030691A2 (cs) |
| HU (1) | HUP0303144A3 (cs) |
| IS (1) | IS6897A (cs) |
| MX (1) | MXPA03006904A (cs) |
| NO (1) | NO20033433L (cs) |
| PL (1) | PL368563A1 (cs) |
| SK (1) | SK10792003A3 (cs) |
| WO (1) | WO2002062786A1 (cs) |
| YU (1) | YU61103A (cs) |
| ZA (1) | ZA200305652B (cs) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20030691A2 (en) * | 2001-02-02 | 2005-04-30 | Teva Pharmaceutical Industries Ltd. | Processes for the production of substituted 2-(2-pyridylmethyl)sulfinyl-benzimidazoles |
| AU2003224779A1 (en) * | 2002-03-27 | 2003-10-13 | Teva Pharmaceutical Industries Ltd. | Lansoprazole polymorphs and processes for preparation thereof |
| AU2003268034A1 (en) * | 2002-07-26 | 2004-02-16 | Teva Pharmaceutical Industries Ltd. | Preparation of lansoprazole and related compounds |
| AU2003258335A1 (en) * | 2002-08-21 | 2004-03-11 | Teva Pharmaceutical Industries Ltd. | A method for the purification of lansoprazole |
| JP2005527638A (ja) * | 2002-11-18 | 2005-09-15 | テバ ファーマシューティカル インダストリーズ リミティド | ５００ｐｐｍより多く約３０００ｐｐｍまでの水および２００ｐｐｍより多く約５０００ｐｐｍまでのアルコールを含有する安定ランソプラゾール |
| CA2510849A1 (en) | 2002-12-19 | 2004-07-08 | Teva Pharmaceutical Industries Ltd | Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates |
| US7678816B2 (en) * | 2003-02-05 | 2010-03-16 | Teva Pharmaceutical Industries Ltd. | Method of stabilizing lansoprazole |
| EP1601667A2 (en) * | 2003-03-12 | 2005-12-07 | Teva Pharmaceutical Industries Limited | Crystalline and amorphous solids of pantoprazole and processes for their preparation |
| EP1615913A2 (en) * | 2003-06-10 | 2006-01-18 | Teva Pharmaceutical Industries Limited | Process for preparing 2-(pyridinyl)methyl sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
| FR2871800B1 (fr) * | 2004-06-17 | 2006-08-25 | Sidem Pharma Sa Sa | Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique |
| ZA200706613B (en) | 2004-12-16 | 2009-03-25 | Cipla Ltd | Process |
| EP1681056A1 (en) | 2005-01-14 | 2006-07-19 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for preparing lansoprazole |
| EP1893602A2 (en) * | 2005-05-06 | 2008-03-05 | Medichem, S.A. | Pantoprazole free acid form iii |
| CN1919844B (zh) * | 2006-09-01 | 2010-05-12 | 武汉工程大学 | 水相氧化合成兰索拉唑的方法 |
| WO2010039885A2 (en) * | 2008-09-30 | 2010-04-08 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of dexlansoprazole |
| WO2010134099A1 (en) * | 2009-05-21 | 2010-11-25 | Cadila Healthcare Limited | One pot process for preparing omeprazole and related compounds |
| CN108623564B (zh) * | 2017-03-17 | 2022-11-04 | 江苏豪森药业集团有限公司 | 一种雷贝拉唑类似物的制备方法 |
| CN111072633A (zh) * | 2019-12-19 | 2020-04-28 | 山东达因海洋生物制药股份有限公司 | 一种埃索美拉唑镁三水合物的制备方法 |
| CN112174934B (zh) * | 2020-10-15 | 2023-12-22 | 成都百泉生物医药科技有限公司 | 一种奥美拉唑的合成方法及其合成设备 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1140119A (en) | 1978-04-03 | 1983-01-25 | Joseph Torremans | N-heterocyclyl-4-piperidinamines |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| GB2069492B (en) | 1980-02-20 | 1984-02-29 | Wyeth John & Brother Ltd | Sulphur compounds |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| DK171989B1 (da) | 1987-08-04 | 1997-09-08 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler |
| SE9002043D0 (sv) | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| WO1993006097A1 (en) | 1991-09-20 | 1993-04-01 | Merck & Co., Inc. | Novel process for the preparation of anti-ulcer agents |
| ES2063705B1 (es) * | 1993-06-14 | 1995-07-16 | S A L V A T Lab Sa | Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion. |
| SK283805B6 (sk) * | 1996-09-09 | 2004-02-03 | Slovakofarma, A. S. | Spôsob prípravy omeprazolu |
| SE9704183D0 (sv) | 1997-11-14 | 1997-11-14 | Astra Ab | New process |
| EE04576B1 (et) * | 1997-12-08 | 2006-02-15 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Suposiit happes ebapüsivate toimeainete tarbeks, selle valmistamismeetod, toimeaineühik ja selle valmistamismeetod ning preparaat |
| GB9805558D0 (en) * | 1998-03-17 | 1998-05-13 | Knoll Ag | Chemical process` |
| US6303787B1 (en) | 1998-05-27 | 2001-10-16 | Natco Pharma Limited | Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates |
| SI20019A (sl) * | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
| JP4047993B2 (ja) * | 1999-01-04 | 2008-02-13 | 理想科学工業株式会社 | 孔版印刷方法 |
| US6245913B1 (en) * | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
| ES2163372B1 (es) | 2000-03-13 | 2003-05-01 | Esteve Quimica Sa | Procedimiento de oxidacion de un grupo tioeter a sulfoxido. |
| HRP20030691A2 (en) | 2001-02-02 | 2005-04-30 | Teva Pharmaceutical Industries Ltd. | Processes for the production of substituted 2-(2-pyridylmethyl)sulfinyl-benzimidazoles |
-
2002
- 2002-02-04 HR HR20030691A patent/HRP20030691A2/xx not_active Application Discontinuation
- 2002-02-04 PL PL02368563A patent/PL368563A1/xx not_active Application Discontinuation
- 2002-02-04 ZA ZA200305652A patent/ZA200305652B/en unknown
- 2002-02-04 EP EP08010970A patent/EP1970374A1/en not_active Ceased
- 2002-02-04 MX MXPA03006904A patent/MXPA03006904A/es not_active Application Discontinuation
- 2002-02-04 CN CNB028044851A patent/CN100347167C/zh not_active Expired - Fee Related
- 2002-02-04 CN CNA200510086094XA patent/CN1781918A/zh active Pending
- 2002-02-04 ES ES02706135T patent/ES2209678T1/es active Pending
- 2002-02-04 CZ CZ20032351A patent/CZ20032351A3/cs unknown
- 2002-02-04 DE DE0001363901T patent/DE02706135T1/de active Pending
- 2002-02-04 YU YU61103A patent/YU61103A/sh unknown
- 2002-02-04 CA CA002436467A patent/CA2436467A1/en not_active Abandoned
- 2002-02-04 JP JP2002563139A patent/JP2004524303A/ja active Pending
- 2002-02-04 US US10/066,850 patent/US7129358B2/en not_active Expired - Fee Related
- 2002-02-04 KR KR10-2003-7010217A patent/KR20040029966A/ko not_active Ceased
- 2002-02-04 WO PCT/US2002/003225 patent/WO2002062786A1/en active Application Filing
- 2002-02-04 SK SK1079-2003A patent/SK10792003A3/sk not_active Application Discontinuation
- 2002-02-04 HU HU0303144A patent/HUP0303144A3/hu unknown
- 2002-02-04 CN CNA2006100819206A patent/CN1876647A/zh active Pending
- 2002-02-04 EP EP02706135A patent/EP1363901A4/en not_active Withdrawn
-
2003
- 2003-07-29 IS IS6897A patent/IS6897A/is unknown
- 2003-08-01 NO NO20033433A patent/NO20033433L/no not_active Application Discontinuation
-
2006
- 2006-09-05 US US11/514,964 patent/US20060293363A1/en not_active Abandoned
-
2007
- 2007-10-09 US US11/973,744 patent/US20080091024A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO20033433L (no) | 2003-09-25 |
| CN1876647A (zh) | 2006-12-13 |
| KR20040029966A (ko) | 2004-04-08 |
| IS6897A (is) | 2003-07-29 |
| ZA200305652B (en) | 2004-07-22 |
| MXPA03006904A (es) | 2004-12-06 |
| EP1363901A1 (en) | 2003-11-26 |
| HUP0303144A2 (hu) | 2004-03-01 |
| NO20033433D0 (no) | 2003-08-01 |
| CN1489585A (zh) | 2004-04-14 |
| WO2002062786A1 (en) | 2002-08-15 |
| CZ20032351A3 (cs) | 2004-08-18 |
| DE02706135T1 (de) | 2004-05-19 |
| US20080091024A1 (en) | 2008-04-17 |
| EP1363901A4 (en) | 2005-08-31 |
| CA2436467A1 (en) | 2002-08-15 |
| CN100347167C (zh) | 2007-11-07 |
| ES2209678T1 (es) | 2004-07-01 |
| JP2004524303A (ja) | 2004-08-12 |
| US7129358B2 (en) | 2006-10-31 |
| CN1781918A (zh) | 2006-06-07 |
| US20030036554A1 (en) | 2003-02-20 |
| YU61103A (sh) | 2006-05-25 |
| SK10792003A3 (sk) | 2004-07-07 |
| HUP0303144A3 (en) | 2007-08-28 |
| EP1970374A1 (en) | 2008-09-17 |
| PL368563A1 (en) | 2005-04-04 |
| US20060293363A1 (en) | 2006-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20090202 Year of fee payment: 8 |
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| ODBI | Application refused |