HRP20030220B1 - Bicyclic heteroaromatic compounds - Google Patents

Bicyclic heteroaromatic compounds

Info

Publication number
HRP20030220B1
HRP20030220B1 HR20030220A HRP20030220A HRP20030220B1 HR P20030220 B1 HRP20030220 B1 HR P20030220B1 HR 20030220 A HR20030220 A HR 20030220A HR P20030220 A HRP20030220 A HR P20030220A HR P20030220 B1 HRP20030220 B1 HR P20030220B1
Authority
HR
Croatia
Prior art keywords
bicyclic heteroaromatic
heteroaromatic compounds
thieno
methylthio
carboxamide
Prior art date
Application number
HR20030220A
Other languages
English (en)
Croatian (hr)
Inventor
Marius Timmers Cornelis
Frederik Johan Karstens Willem
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of HRP20030220A2 publication Critical patent/HRP20030220A2/hr
Publication of HRP20030220B1 publication Critical patent/HRP20030220B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20030220A 2000-09-22 2003-03-21 Bicyclic heteroaromatic compounds HRP20030220B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00203287 2000-09-22
PCT/EP2001/010743 WO2002024703A1 (en) 2000-09-22 2001-09-17 Bicyclic heteroaromatic compounds

Publications (2)

Publication Number Publication Date
HRP20030220A2 HRP20030220A2 (en) 2003-06-30
HRP20030220B1 true HRP20030220B1 (en) 2011-10-31

Family

ID=8172046

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030220A HRP20030220B1 (en) 2000-09-22 2003-03-21 Bicyclic heteroaromatic compounds

Country Status (32)

Country Link
US (2) US7229990B2 (es)
EP (2) EP1886999A3 (es)
JP (1) JP4977940B2 (es)
KR (1) KR100860040B1 (es)
CN (1) CN1247594C (es)
AR (1) AR030784A1 (es)
AT (1) ATE384726T1 (es)
AU (2) AU2002213929B2 (es)
BR (1) BR0113987A (es)
CA (1) CA2422054C (es)
CY (1) CY1107308T1 (es)
CZ (1) CZ297136B6 (es)
DE (1) DE60132607T2 (es)
DK (1) DK1322651T3 (es)
EC (1) ECSP034523A (es)
ES (1) ES2299524T3 (es)
HK (1) HK1054942A1 (es)
HR (1) HRP20030220B1 (es)
HU (1) HU229422B1 (es)
IL (2) IL154624A0 (es)
IS (1) IS2531B (es)
MX (1) MXPA03002478A (es)
NO (1) NO328683B1 (es)
NZ (1) NZ524444A (es)
PE (1) PE20020537A1 (es)
PL (1) PL207755B1 (es)
PT (1) PT1322651E (es)
RU (1) RU2271360C2 (es)
SK (1) SK287554B6 (es)
TW (1) TWI290143B (es)
WO (1) WO2002024703A1 (es)
ZA (1) ZA200301588B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1247594C (zh) * 2000-09-22 2006-03-29 阿克佐诺贝尔公司 二环杂芳族化合物
TW200407127A (en) 2002-08-21 2004-05-16 Astrazeneca Ab Chemical compounds
US7674822B2 (en) 2004-11-24 2010-03-09 Wyeth PTP1b inhibitors
US7737155B2 (en) * 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
CA2608405A1 (en) * 2005-05-17 2006-11-23 Schering Corporation Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
WO2007136776A2 (en) * 2006-05-17 2007-11-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pyrimidine low molecular weight ligands for modulating hormone receptors
WO2009132980A1 (en) 2008-04-29 2009-11-05 F. Hoffmann-La Roche Ag Pyrimidinyl pyridone inhibitors of jnk.
JP5718233B2 (ja) 2008-10-20 2015-05-13 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 甲状腺刺激ホルモン受容体（ｔｓｈｒ）の低分子量アゴニスト
EP2563777A4 (en) 2010-04-08 2013-09-04 Us Health INVERSE AGONISTS AND NEUTRAL AGONISTS FOR THE TSH RECEPTOR
CN108707151B (zh) * 2011-08-23 2022-06-03 阿萨纳生物科技有限责任公司 嘧啶并-哒嗪酮化合物及其用途
CN113680386B (zh) * 2021-08-23 2023-08-11 深圳湾实验室坪山生物医药研发转化中心 氮杂环卡宾-方酰胺双功能催化剂及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
WO2000061586A1 (en) * 1999-04-08 2000-10-19 Akzo Nobel N.V. Bicyclic heteroaromatic compounds useful as lh agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU712019B2 (en) * 1996-05-20 1999-10-28 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
CN1247594C (zh) * 2000-09-22 2006-03-29 阿克佐诺贝尔公司 二环杂芳族化合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
WO2000061586A1 (en) * 1999-04-08 2000-10-19 Akzo Nobel N.V. Bicyclic heteroaromatic compounds useful as lh agonists

Also Published As

Publication number Publication date
WO2002024703A1 (en) 2002-03-28
NZ524444A (en) 2004-03-26
CN1247594C (zh) 2006-03-29
EP1322651B1 (en) 2008-01-23
CZ2003828A3 (cs) 2003-08-13
CA2422054C (en) 2011-01-11
JP4977940B2 (ja) 2012-07-18
ZA200301588B (en) 2004-06-22
US7618963B2 (en) 2009-11-17
IS6732A (is) 2003-02-28
PL207755B1 (pl) 2011-01-31
US20070197527A1 (en) 2007-08-23
NO20031314L (no) 2003-03-21
SK287554B6 (sk) 2011-01-04
PT1322651E (pt) 2008-02-28
ECSP034523A (es) 2003-04-25
PE20020537A1 (es) 2002-06-20
IS2531B (is) 2009-07-15
EP1322651A1 (en) 2003-07-02
DE60132607D1 (de) 2008-03-13
DK1322651T3 (da) 2008-06-02
EP1886999A2 (en) 2008-02-13
CA2422054A1 (en) 2002-03-28
US20030225113A1 (en) 2003-12-04
NO20031314D0 (no) 2003-03-21
BR0113987A (pt) 2003-08-12
ATE384726T1 (de) 2008-02-15
JP2004509896A (ja) 2004-04-02
IL154624A (en) 2009-09-01
IL154624A0 (en) 2003-09-17
PL360675A1 (en) 2004-09-20
US7229990B2 (en) 2007-06-12
CZ297136B6 (cs) 2006-09-13
RU2271360C2 (ru) 2006-03-10
ES2299524T3 (es) 2008-06-01
KR20030040483A (ko) 2003-05-22
CY1107308T1 (el) 2012-11-21
HU229422B1 (hu) 2013-12-30
NO328683B1 (no) 2010-04-26
CN1462273A (zh) 2003-12-17
SK3312003A3 (en) 2003-08-05
EP1886999A3 (en) 2008-03-12
AR030784A1 (es) 2003-09-03
HRP20030220A2 (en) 2003-06-30
AU2002213929B2 (en) 2006-04-13
MXPA03002478A (es) 2004-05-05
TWI290143B (en) 2007-11-21
HUP0302648A2 (hu) 2003-11-28
DE60132607T2 (de) 2009-01-29
HK1054942A1 (en) 2003-12-19
KR100860040B1 (ko) 2008-09-25
EP1886999A8 (en) 2010-08-04
HUP0302648A3 (en) 2004-11-29
AU1392902A (en) 2002-04-02

Similar Documents

Publication Publication Date Title
HRP20010573B1 (en) Tricyclic inhibitors of poly(adp-ribose) polymerases
PT1289992E (pt) Nova forma cristalina de um composto de triazolo (4,5-d) pirimidina
CA2416867A1 (en) Cyclopentanoindoles, compositions containing such compounds and methods of treatment
MY134892A (en) Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines and their use
GB0124627D0 (en) Novel compounds
HRP20030220B1 (en) Bicyclic heteroaromatic compounds
MA26824A1 (fr) 5-(2-substitué-5-hétérocyclylsulfonylpyrid-3-yl)-dihydropyrazolo[4,3-d]pyrimidine-7-ones servant d'inhibiteurs de phosphodiestérase.
SI1379522T1 (en) DIHYDRO-BENZO(b)(1,4)DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I
HRP20010117B1 (en) Novel salt form of pantoprazole
DZ3266A1 (fr) Pyrido[2,3-d]pyrimidine-2,7-diamine inhibiteurs de kinase
MXPA02011319A (es) Analogos antitumorales de ecteinascidina 743.
HRP20010238B1 (en) 2-methyl-thieno-benzodiazepine formulation
DE60005031D1 (de) Partikel mit kontrollierter freisetzungsrate
HK1061026A1 (en) 3,7-Diazabicyclo 3.3.1Ü formulations as antiarhythmic compounds
MXPA03008965A (es) Uso de compuestos de imidazo [1,2-a]-piridinas sustituidas como medicamentos.
GR1002883B (el) Νεα παραγωγα της 2, 3-βενζοδιαζεπινης
AU5539899A (en) Novel triazolo(4,5-(d))pyrimidine compounds
TR199901017A2 (xx) B�cek ilac� terkibi.
MXPA03004498A (es) Uso de pirazolo (4,3-d)pirimidinas.
AU9259501A (en) Interphenylene 7-oxabicyclic(2.2.1)heptane oxazoles as prostaglandin F<sub>2alpha</sub> antagonists
GB2418915B (en) Fragrance compositions comprising benzo[4,5]thieno[3,2-B]pyran-2-one
AU9069201A (en) Interheteroaryl 7-oxabicyclic (2.2.1)heptane oxazoles as prostaglandin F<sub>2alpha</sub> antagonists
PL366629A1 (en) 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds
PL356668A1 (en) Novel substituted pyrazolo[4,3-e
HRP980585B1 (en) Sulfonamide substituted fused five-membered ring compounds, their use as medicaments as well as pharmaceutical compositions containing them

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: N.V. ORGANON, NL

B1PR Patent granted
PPPP Transfer of rights

Owner name: MSD OSS B.V., NL

PPPP Transfer of rights

Owner name: ORGANON BIOSCIENCES NEDERLAND B.V., NL

ODRP Renewal fee for the maintenance of a patent

Payment date: 20140826

Year of fee payment: 14

PBON Lapse due to non-payment of renewal fee

Effective date: 20150917