HRP20020497B1 - Amycomycin, a process for its production and its use a pharmaceutical - Google Patents
Amycomycin, a process for its production and its use a pharmaceuticalInfo
- Publication number
- HRP20020497B1 HRP20020497B1 HR20020497A HRP20020497A HRP20020497B1 HR P20020497 B1 HRP20020497 B1 HR P20020497B1 HR 20020497 A HR20020497 A HR 20020497A HR P20020497 A HRP20020497 A HR P20020497A HR P20020497 B1 HRP20020497 B1 HR P20020497B1
- Authority
- HR
- Croatia
- Prior art keywords
- amycomycin
- pharmaceutical
- production
- stereoisomeric
- formulas
- Prior art date
Links
- VNFAKMBHDHVYLZ-HSTNYJNZSA-N (3E,5Z)-1-methyl-5-(2-methylpropylidene)-3-[(2E,20E,24E)-1,5,7,11,13,17,19,26,27,29,31,35,37,41,43-pentadecahydroxy-2,10,12,18,20,22,24,32,40,42,44-undecamethyl-23-oxopentatetraconta-2,20,24-trienylidene]pyrrolidine-2,4-dione Chemical compound CC(C)\C=C1/N(C)C(=O)\C(=C(\O)/C(/C)=C/CC(O)CC(O)CCC(C)C(O)C(C)C(O)CCCC(O)C(C)C(O)C(\C)=C\C(C)C(=O)C(\C)=C\C(O)C(O)CC(O)CC(O)C(C)CCC(O)CC(O)CCC(C)C(O)C(C)C(O)C(C)C)C1=O VNFAKMBHDHVYLZ-HSTNYJNZSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99124456A EP1106604A1 (en) | 1999-12-08 | 1999-12-08 | Amycomycin, a process for its production and its use as a pharmaceutical |
| PCT/EP2000/011752 WO2001042210A1 (en) | 1999-12-08 | 2000-11-25 | Amycomycin, a process for its production and its use as a pharmaceutical |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20020497A2 HRP20020497A2 (en) | 2004-08-31 |
| HRP20020497B1 true HRP20020497B1 (en) | 2006-04-30 |
Family
ID=8239554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20020497A HRP20020497B1 (en) | 1999-12-08 | 2002-06-06 | Amycomycin, a process for its production and its use a pharmaceutical |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6642391B2 (zh) |
| EP (2) | EP1106604A1 (zh) |
| JP (1) | JP4750993B2 (zh) |
| KR (1) | KR100728514B1 (zh) |
| CN (1) | CN1217929C (zh) |
| AT (1) | ATE298744T1 (zh) |
| AU (1) | AU781398B2 (zh) |
| BR (1) | BR0016223A (zh) |
| CA (1) | CA2393518C (zh) |
| CZ (1) | CZ294370B6 (zh) |
| DE (1) | DE60021109T2 (zh) |
| DK (1) | DK1237866T3 (zh) |
| EE (1) | EE05219B1 (zh) |
| ES (1) | ES2243332T3 (zh) |
| HK (1) | HK1048998A1 (zh) |
| HR (1) | HRP20020497B1 (zh) |
| HU (1) | HU225194B1 (zh) |
| IL (2) | IL149904A0 (zh) |
| ME (1) | ME00182B (zh) |
| NO (1) | NO322565B1 (zh) |
| PL (1) | PL201809B1 (zh) |
| PT (1) | PT1237866E (zh) |
| RS (1) | RS50288B (zh) |
| RU (1) | RU2261916C2 (zh) |
| SI (1) | SI1237866T1 (zh) |
| SK (1) | SK286776B6 (zh) |
| WO (1) | WO2001042210A1 (zh) |
| ZA (1) | ZA200204420B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102417919B (zh) * | 2011-09-02 | 2017-05-24 | 山东鲁抗医药股份有限公司 | 一种发酵法生产高纯度替考拉宁的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8700513D0 (en) * | 1987-01-09 | 1987-02-11 | Pfizer Ltd | Antibiotics produced by fermentation |
| CA2016382A1 (en) * | 1989-05-12 | 1990-11-12 | Marvin M. Hoehn | A59770 antibiotics |
| JPH05163289A (ja) * | 1991-08-27 | 1993-06-29 | Microbial Chem Res Found | 新規な免疫抑制物質、ｍｉ７１０−５１ｆ６物質およびその製造法 |
| JPH05286990A (ja) * | 1992-04-08 | 1993-11-02 | Meiji Seika Kaisha Ltd | 新規マクロライド抗生物質および微生物変換を利用したマクロライド抗生物質の製造法 |
| JP3107455B2 (ja) * | 1992-05-08 | 2000-11-06 | 財団法人微生物化学研究会 | 新規抗生物質ｍｉ４８１−４２ｆ４−ａ及びその製造方法 |
| JPH05317068A (ja) * | 1992-05-14 | 1993-12-03 | Kaiyo Bio Technol Kenkyusho:Kk | 抗生物質マグネシジンの一成分の選択的製造法 |
| JPH0733736A (ja) * | 1993-07-26 | 1995-02-03 | Microbial Chem Res Found | 新規抗生物質アジセマイシンｂおよびその製造方法 |
| JPH09157266A (ja) * | 1995-12-04 | 1997-06-17 | Microbial Chem Res Found | 新規抗生物質エポキシキノマイシンａおよびｂとその製造法 |
| EP0816539A1 (de) | 1996-07-05 | 1998-01-07 | Maschinenfabrik Rieter Ag | Verfahren und Vorrichtung zur Produktionssteuerung an einer Karde |
| JPH1045738A (ja) * | 1996-07-29 | 1998-02-17 | Microbial Chem Res Found | 抗生物質エポキシキノマイシンｃおよびｄとその製造法ならびに抗リウマチ剤 |
| JPH10114777A (ja) * | 1996-10-09 | 1998-05-06 | Microbial Chem Res Found | 抗生物質スピロキシマイシンとその製造法 |
-
1999
- 1999-12-08 EP EP99124456A patent/EP1106604A1/en not_active Withdrawn
-
2000
- 2000-11-25 PL PL355627A patent/PL201809B1/pl unknown
- 2000-11-25 SI SI200030729T patent/SI1237866T1/xx unknown
- 2000-11-25 BR BR0016223-0A patent/BR0016223A/pt not_active Application Discontinuation
- 2000-11-25 PT PT00983165T patent/PT1237866E/pt unknown
- 2000-11-25 JP JP2001543511A patent/JP4750993B2/ja not_active Expired - Fee Related
- 2000-11-25 CA CA002393518A patent/CA2393518C/en not_active Expired - Fee Related
- 2000-11-25 ME MEP-2008-285A patent/ME00182B/me unknown
- 2000-11-25 KR KR1020027007292A patent/KR100728514B1/ko not_active IP Right Cessation
- 2000-11-25 AT AT00983165T patent/ATE298744T1/de active
- 2000-11-25 EP EP00983165A patent/EP1237866B1/en not_active Expired - Lifetime
- 2000-11-25 CZ CZ20021891A patent/CZ294370B6/cs not_active IP Right Cessation
- 2000-11-25 ES ES00983165T patent/ES2243332T3/es not_active Expired - Lifetime
- 2000-11-25 HU HU0203593A patent/HU225194B1/hu not_active IP Right Cessation
- 2000-11-25 RS YUP-131/02A patent/RS50288B/sr unknown
- 2000-11-25 WO PCT/EP2000/011752 patent/WO2001042210A1/en active IP Right Grant
- 2000-11-25 AU AU20019/01A patent/AU781398B2/en not_active Ceased
- 2000-11-25 SK SK787-2002A patent/SK286776B6/sk not_active IP Right Cessation
- 2000-11-25 EE EEP200200280A patent/EE05219B1/xx not_active IP Right Cessation
- 2000-11-25 RU RU2002118116/13A patent/RU2261916C2/ru not_active IP Right Cessation
- 2000-11-25 DK DK00983165T patent/DK1237866T3/da active
- 2000-11-25 IL IL14990400A patent/IL149904A0/xx active IP Right Grant
- 2000-11-25 DE DE60021109T patent/DE60021109T2/de not_active Expired - Lifetime
- 2000-11-25 CN CN008135207A patent/CN1217929C/zh not_active Expired - Fee Related
- 2000-12-07 US US09/730,844 patent/US6642391B2/en not_active Expired - Lifetime
-
2002
- 2002-05-29 IL IL149904A patent/IL149904A/en not_active IP Right Cessation
- 2002-06-03 ZA ZA200204420A patent/ZA200204420B/xx unknown
- 2002-06-05 NO NO20022654A patent/NO322565B1/no not_active IP Right Cessation
- 2002-06-06 HR HR20020497A patent/HRP20020497B1/xx not_active IP Right Cessation
-
2003
- 2003-02-18 HK HK03101176A patent/HK1048998A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, DE |
|
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20160928 Year of fee payment: 17 |
|
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20171125 |