ME00182B - Amycomycin, postupak za njegovu proizvodnju i njegova upotreba kao farmaceutika - Google Patents
Amycomycin, postupak za njegovu proizvodnju i njegova upotreba kao farmaceutikaInfo
- Publication number
- ME00182B ME00182B MEP-2008-285A MEP28508A ME00182B ME 00182 B ME00182 B ME 00182B ME P28508 A MEP28508 A ME P28508A ME 00182 B ME00182 B ME 00182B
- Authority
- ME
- Montenegro
- Prior art keywords
- amycomycin
- pharmaceutical
- production
- stereoisomeric
- dsm
- Prior art date
Links
- VNFAKMBHDHVYLZ-HSTNYJNZSA-N (3E,5Z)-1-methyl-5-(2-methylpropylidene)-3-[(2E,20E,24E)-1,5,7,11,13,17,19,26,27,29,31,35,37,41,43-pentadecahydroxy-2,10,12,18,20,22,24,32,40,42,44-undecamethyl-23-oxopentatetraconta-2,20,24-trienylidene]pyrrolidine-2,4-dione Chemical compound CC(C)\C=C1/N(C)C(=O)\C(=C(\O)/C(/C)=C/CC(O)CC(O)CCC(C)C(O)C(C)C(O)CCCC(O)C(C)C(O)C(\C)=C\C(C)C(=O)C(\C)=C\C(O)C(O)CC(O)CC(O)C(C)CCC(O)CC(O)CCC(C)C(O)C(C)C(O)C(C)C)C1=O VNFAKMBHDHVYLZ-HSTNYJNZSA-N 0.000 title abstract 2
- 241001522168 Amycolatopsis sp. Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Jedinjenje nazvano Amycomycin iz formule (I) i njegove farmaceutski prihvatljive soli i derivati, u svim njihovim stereoizomernim i tautomernim oblicima moguće je dobiti uzgajanjem mikroorganizma Amycolatopsis sp ., ST101170 (DSM 12216) i može se koristiti kao farmaceutik. naročito kao antibiotik.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99124456A EP1106604A1 (en) | 1999-12-08 | 1999-12-08 | Amycomycin, a process for its production and its use as a pharmaceutical |
EP00983165A EP1237866B1 (en) | 1999-12-08 | 2000-11-25 | Amycomycin, a process for its production and its use as a pharmaceutical |
PCT/EP2000/011752 WO2001042210A1 (en) | 1999-12-08 | 2000-11-25 | Amycomycin, a process for its production and its use as a pharmaceutical |
Publications (2)
Publication Number | Publication Date |
---|---|
MEP28508A MEP28508A (en) | 2010-10-10 |
ME00182B true ME00182B (me) | 2010-10-10 |
Family
ID=8239554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2008-285A ME00182B (me) | 1999-12-08 | 2000-11-25 | Amycomycin, postupak za njegovu proizvodnju i njegova upotreba kao farmaceutika |
Country Status (28)
Country | Link |
---|---|
US (1) | US6642391B2 (me) |
EP (2) | EP1106604A1 (me) |
JP (1) | JP4750993B2 (me) |
KR (1) | KR100728514B1 (me) |
CN (1) | CN1217929C (me) |
AT (1) | ATE298744T1 (me) |
AU (1) | AU781398B2 (me) |
BR (1) | BR0016223A (me) |
CA (1) | CA2393518C (me) |
CZ (1) | CZ294370B6 (me) |
DE (1) | DE60021109T2 (me) |
DK (1) | DK1237866T3 (me) |
EE (1) | EE05219B1 (me) |
ES (1) | ES2243332T3 (me) |
HK (1) | HK1048998A1 (me) |
HR (1) | HRP20020497B1 (me) |
HU (1) | HU225194B1 (me) |
IL (2) | IL149904A0 (me) |
ME (1) | ME00182B (me) |
NO (1) | NO322565B1 (me) |
PL (1) | PL201809B1 (me) |
PT (1) | PT1237866E (me) |
RS (1) | RS50288B (me) |
RU (1) | RU2261916C2 (me) |
SI (1) | SI1237866T1 (me) |
SK (1) | SK286776B6 (me) |
WO (1) | WO2001042210A1 (me) |
ZA (1) | ZA200204420B (me) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102417919B (zh) * | 2011-09-02 | 2017-05-24 | 山东鲁抗医药股份有限公司 | 一种发酵法生产高纯度替考拉宁的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8700513D0 (en) * | 1987-01-09 | 1987-02-11 | Pfizer Ltd | Antibiotics produced by fermentation |
CA2016382A1 (en) * | 1989-05-12 | 1990-11-12 | Marvin M. Hoehn | A59770 antibiotics |
JPH05163289A (ja) * | 1991-08-27 | 1993-06-29 | Microbial Chem Res Found | 新規な免疫抑制物質、mi710−51f6物質およびその製造法 |
JPH05286990A (ja) * | 1992-04-08 | 1993-11-02 | Meiji Seika Kaisha Ltd | 新規マクロライド抗生物質および微生物変換を利用したマクロライド抗生物質の製造法 |
JP3107455B2 (ja) * | 1992-05-08 | 2000-11-06 | 財団法人微生物化学研究会 | 新規抗生物質mi481−42f4−a及びその製造方法 |
JPH05317068A (ja) * | 1992-05-14 | 1993-12-03 | Kaiyo Bio Technol Kenkyusho:Kk | 抗生物質マグネシジンの一成分の選択的製造法 |
JPH0733736A (ja) * | 1993-07-26 | 1995-02-03 | Microbial Chem Res Found | 新規抗生物質アジセマイシンbおよびその製造方法 |
JPH09157266A (ja) * | 1995-12-04 | 1997-06-17 | Microbial Chem Res Found | 新規抗生物質エポキシキノマイシンaおよびbとその製造法 |
EP0816539A1 (de) | 1996-07-05 | 1998-01-07 | Maschinenfabrik Rieter Ag | Verfahren und Vorrichtung zur Produktionssteuerung an einer Karde |
JPH1045738A (ja) * | 1996-07-29 | 1998-02-17 | Microbial Chem Res Found | 抗生物質エポキシキノマイシンcおよびdとその製造法ならびに抗リウマチ剤 |
JPH10114777A (ja) * | 1996-10-09 | 1998-05-06 | Microbial Chem Res Found | 抗生物質スピロキシマイシンとその製造法 |
-
1999
- 1999-12-08 EP EP99124456A patent/EP1106604A1/en not_active Withdrawn
-
2000
- 2000-11-25 BR BR0016223-0A patent/BR0016223A/pt not_active Application Discontinuation
- 2000-11-25 DE DE60021109T patent/DE60021109T2/de not_active Expired - Lifetime
- 2000-11-25 CZ CZ20021891A patent/CZ294370B6/cs not_active IP Right Cessation
- 2000-11-25 IL IL14990400A patent/IL149904A0/xx active IP Right Grant
- 2000-11-25 SI SI200030729T patent/SI1237866T1/xx unknown
- 2000-11-25 EP EP00983165A patent/EP1237866B1/en not_active Expired - Lifetime
- 2000-11-25 RU RU2002118116/13A patent/RU2261916C2/ru not_active IP Right Cessation
- 2000-11-25 CA CA002393518A patent/CA2393518C/en not_active Expired - Fee Related
- 2000-11-25 HU HU0203593A patent/HU225194B1/hu not_active IP Right Cessation
- 2000-11-25 PL PL355627A patent/PL201809B1/pl unknown
- 2000-11-25 WO PCT/EP2000/011752 patent/WO2001042210A1/en active IP Right Grant
- 2000-11-25 RS YUP-131/02A patent/RS50288B/sr unknown
- 2000-11-25 DK DK00983165T patent/DK1237866T3/da active
- 2000-11-25 EE EEP200200280A patent/EE05219B1/xx not_active IP Right Cessation
- 2000-11-25 SK SK787-2002A patent/SK286776B6/sk not_active IP Right Cessation
- 2000-11-25 JP JP2001543511A patent/JP4750993B2/ja not_active Expired - Fee Related
- 2000-11-25 ME MEP-2008-285A patent/ME00182B/me unknown
- 2000-11-25 KR KR1020027007292A patent/KR100728514B1/ko not_active IP Right Cessation
- 2000-11-25 PT PT00983165T patent/PT1237866E/pt unknown
- 2000-11-25 AU AU20019/01A patent/AU781398B2/en not_active Ceased
- 2000-11-25 CN CN008135207A patent/CN1217929C/zh not_active Expired - Fee Related
- 2000-11-25 ES ES00983165T patent/ES2243332T3/es not_active Expired - Lifetime
- 2000-11-25 AT AT00983165T patent/ATE298744T1/de active
- 2000-12-07 US US09/730,844 patent/US6642391B2/en not_active Expired - Lifetime
-
2002
- 2002-05-29 IL IL149904A patent/IL149904A/en not_active IP Right Cessation
- 2002-06-03 ZA ZA200204420A patent/ZA200204420B/xx unknown
- 2002-06-05 NO NO20022654A patent/NO322565B1/no not_active IP Right Cessation
- 2002-06-06 HR HR20020497A patent/HRP20020497B1/xx not_active IP Right Cessation
-
2003
- 2003-02-18 HK HK03101176A patent/HK1048998A1/xx not_active IP Right Cessation
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