YU12191A - Kristalni hidrohlorid novog beta-laktamskog antibiotika i postupak za njegovo dobijanje - Google Patents

Kristalni hidrohlorid novog beta-laktamskog antibiotika i postupak za njegovo dobijanje

Info

Publication number
YU12191A
YU12191A YU12191A YU12191A YU12191A YU 12191 A YU12191 A YU 12191A YU 12191 A YU12191 A YU 12191A YU 12191 A YU12191 A YU 12191A YU 12191 A YU12191 A YU 12191A
Authority
YU
Yugoslavia
Prior art keywords
procedure
obtaining
lactam antibiotic
new beta
hydrochloride
Prior art date
Application number
YU12191A
Other languages
English (en)
Inventor
R.R. Pfeiffer
Original Assignee
Eli Lilly And Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co. filed Critical Eli Lilly And Co.
Publication of YU12191A publication Critical patent/YU12191A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Opisan je kristalni hidrohlorid novog beta-laktamskog antibiotika formule postupak za njegovo dobijanje i farmaceutske formulacije koje sadrže pomenuti kristalni hidrohlorid, zajedno sa farmaceutski prihvatljivim aditivima.
YU12191A 1990-01-26 1991-01-24 Kristalni hidrohlorid novog beta-laktamskog antibiotika i postupak za njegovo dobijanje YU12191A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47048690A 1990-01-26 1990-01-26

Publications (1)

Publication Number Publication Date
YU12191A true YU12191A (sh) 1994-01-20

Family

ID=23867812

Family Applications (1)

Application Number Title Priority Date Filing Date
YU12191A YU12191A (sh) 1990-01-26 1991-01-24 Kristalni hidrohlorid novog beta-laktamskog antibiotika i postupak za njegovo dobijanje

Country Status (19)

Country Link
EP (1) EP0439353B1 (sh)
JP (1) JPH04234880A (sh)
KR (1) KR910014378A (sh)
CN (1) CN1053611A (sh)
AU (1) AU631960B2 (sh)
CA (1) CA2034592C (sh)
DE (1) DE69118933T2 (sh)
ES (1) ES2087240T3 (sh)
FI (1) FI910365A (sh)
HU (1) HU208972B (sh)
IE (1) IE910251A1 (sh)
IL (1) IL96979A0 (sh)
MX (1) MX24247A (sh)
NO (1) NO910267L (sh)
NZ (1) NZ236868A (sh)
PT (1) PT96531A (sh)
RU (1) RU1825365C (sh)
YU (1) YU12191A (sh)
ZA (1) ZA91428B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
AU1234999A (en) * 1997-11-10 1999-05-31 Gist-Brocades B.V. Crystallization of beta-lactam compounds
AU2003283624A1 (en) * 2002-11-21 2004-06-15 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
CA1334970C (en) * 1987-10-06 1995-03-28 Carol Elaine Pasini Crystalline .beta.-lactam hydrate
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic

Also Published As

Publication number Publication date
MX24247A (es) 1993-11-01
HUT57207A (en) 1991-11-28
NO910267L (no) 1991-07-29
ES2087240T3 (es) 1996-07-16
FI910365A (fi) 1991-07-27
AU6992391A (en) 1991-08-01
IE910251A1 (en) 1991-07-31
JPH04234880A (ja) 1992-08-24
DE69118933T2 (de) 1996-10-02
CN1053611A (zh) 1991-08-07
HU208972B (en) 1994-02-28
PT96531A (pt) 1991-10-15
FI910365A0 (fi) 1991-01-24
NZ236868A (en) 1992-04-28
EP0439353A1 (en) 1991-07-31
IL96979A0 (en) 1992-03-29
KR910014378A (ko) 1991-08-31
EP0439353B1 (en) 1996-04-24
ZA91428B (en) 1992-09-30
RU1825365C (ru) 1993-06-30
CA2034592A1 (en) 1991-07-27
AU631960B2 (en) 1992-12-10
NO910267D0 (no) 1991-01-23
DE69118933D1 (de) 1996-05-30
HU910263D0 (en) 1991-08-28
CA2034592C (en) 2001-06-05

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