HU910263D0 - Process for producing crystallic hydrochlorides of new beta-lactame antibiotics - Google Patents

Process for producing crystallic hydrochlorides of new beta-lactame antibiotics

Info

Publication number
HU910263D0
HU910263D0 HU91263A HU26391A HU910263D0 HU 910263 D0 HU910263 D0 HU 910263D0 HU 91263 A HU91263 A HU 91263A HU 26391 A HU26391 A HU 26391A HU 910263 D0 HU910263 D0 HU 910263D0
Authority
HU
Hungary
Prior art keywords
crystallic
hydrochlorides
producing
new beta
lactame
Prior art date
Application number
HU91263A
Other languages
Hungarian (hu)
Other versions
HUT57207A (en
HU208972B (en
Inventor
Ralp Robert Pfeiffer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU910263D0 publication Critical patent/HU910263D0/en
Publication of HUT57207A publication Critical patent/HUT57207A/en
Publication of HU208972B publication Critical patent/HU208972B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU91263A 1990-01-26 1991-01-24 Process for producing cristalline hydrochloride of new beta-lactame antibioticum and pharmaceutical preparations containing them HU208972B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47048690A 1990-01-26 1990-01-26

Publications (3)

Publication Number Publication Date
HU910263D0 true HU910263D0 (en) 1991-08-28
HUT57207A HUT57207A (en) 1991-11-28
HU208972B HU208972B (en) 1994-02-28

Family

ID=23867812

Family Applications (1)

Application Number Title Priority Date Filing Date
HU91263A HU208972B (en) 1990-01-26 1991-01-24 Process for producing cristalline hydrochloride of new beta-lactame antibioticum and pharmaceutical preparations containing them

Country Status (19)

Country Link
EP (1) EP0439353B1 (en)
JP (1) JPH04234880A (en)
KR (1) KR910014378A (en)
CN (1) CN1053611A (en)
AU (1) AU631960B2 (en)
CA (1) CA2034592C (en)
DE (1) DE69118933T2 (en)
ES (1) ES2087240T3 (en)
FI (1) FI910365A (en)
HU (1) HU208972B (en)
IE (1) IE910251A1 (en)
IL (1) IL96979A0 (en)
MX (1) MX24247A (en)
NO (1) NO910267L (en)
NZ (1) NZ236868A (en)
PT (1) PT96531A (en)
RU (1) RU1825365C (en)
YU (1) YU12191A (en)
ZA (1) ZA91428B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
AU1234999A (en) * 1997-11-10 1999-05-31 Gist-Brocades B.V. Crystallization of beta-lactam compounds
WO2004046142A1 (en) * 2002-11-21 2004-06-03 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
NO155548C (en) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk PROCEDURE FOR THE PREPARATION OF OPTICALLY ACTIVE CEPHALOSPORIN ANALOGS.
EG18529A (en) * 1987-10-06 1993-04-30 Lilly Co Eli Process for preparing b-lactam hydrate
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic

Also Published As

Publication number Publication date
AU6992391A (en) 1991-08-01
DE69118933T2 (en) 1996-10-02
AU631960B2 (en) 1992-12-10
ES2087240T3 (en) 1996-07-16
FI910365A (en) 1991-07-27
KR910014378A (en) 1991-08-31
EP0439353A1 (en) 1991-07-31
NO910267D0 (en) 1991-01-23
ZA91428B (en) 1992-09-30
CA2034592C (en) 2001-06-05
RU1825365C (en) 1993-06-30
NO910267L (en) 1991-07-29
PT96531A (en) 1991-10-15
MX24247A (en) 1993-11-01
YU12191A (en) 1994-01-20
DE69118933D1 (en) 1996-05-30
HUT57207A (en) 1991-11-28
FI910365A0 (en) 1991-01-24
IL96979A0 (en) 1992-03-29
IE910251A1 (en) 1991-07-31
CA2034592A1 (en) 1991-07-27
JPH04234880A (en) 1992-08-24
CN1053611A (en) 1991-08-07
HU208972B (en) 1994-02-28
EP0439353B1 (en) 1996-04-24
NZ236868A (en) 1992-04-28

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee