DE69118933D1 - Kristallines Hydrochlorid eines neuen beta-Lactam-Antibiotikums und Verfahren zur Herstellung - Google Patents
Kristallines Hydrochlorid eines neuen beta-Lactam-Antibiotikums und Verfahren zur HerstellungInfo
- Publication number
- DE69118933D1 DE69118933D1 DE69118933T DE69118933T DE69118933D1 DE 69118933 D1 DE69118933 D1 DE 69118933D1 DE 69118933 T DE69118933 T DE 69118933T DE 69118933 T DE69118933 T DE 69118933T DE 69118933 D1 DE69118933 D1 DE 69118933D1
- Authority
- DE
- Germany
- Prior art keywords
- manufacture
- lactam antibiotic
- crystalline hydrochloride
- new beta
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47048690A | 1990-01-26 | 1990-01-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69118933D1 true DE69118933D1 (de) | 1996-05-30 |
| DE69118933T2 DE69118933T2 (de) | 1996-10-02 |
Family
ID=23867812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69118933T Expired - Fee Related DE69118933T2 (de) | 1990-01-26 | 1991-01-24 | Kristallines Hydrochlorid eines neuen beta-Lactam-Antibiotikums und Verfahren zur Herstellung |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0439353B1 (de) |
| JP (1) | JPH04234880A (de) |
| KR (1) | KR910014378A (de) |
| CN (1) | CN1053611A (de) |
| AU (1) | AU631960B2 (de) |
| CA (1) | CA2034592C (de) |
| DE (1) | DE69118933T2 (de) |
| ES (1) | ES2087240T3 (de) |
| FI (1) | FI910365A (de) |
| HU (1) | HU208972B (de) |
| IE (1) | IE910251A1 (de) |
| IL (1) | IL96979A0 (de) |
| MX (1) | MX24247A (de) |
| NO (1) | NO910267L (de) |
| NZ (1) | NZ236868A (de) |
| PT (1) | PT96531A (de) |
| RU (1) | RU1825365C (de) |
| YU (1) | YU12191A (de) |
| ZA (1) | ZA91428B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
| US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
| AU1234999A (en) * | 1997-11-10 | 1999-05-31 | Gist-Brocades B.V. | Crystallization of beta-lactam compounds |
| AU2003283624A1 (en) * | 2002-11-21 | 2004-06-15 | Ranbaxy Laboratories Limited | Monohydrate solvates of loracarbef |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO155548C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger. |
| JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
| ZA887409B (en) * | 1987-10-06 | 1990-06-27 | Lilly Co Eli | Crystalline beta-lactam hydrate |
| CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
| CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
-
1991
- 1991-01-18 CA CA002034592A patent/CA2034592C/en not_active Expired - Fee Related
- 1991-01-20 IL IL96979A patent/IL96979A0/xx unknown
- 1991-01-21 PT PT96531A patent/PT96531A/pt not_active Application Discontinuation
- 1991-01-21 ZA ZA91428A patent/ZA91428B/xx unknown
- 1991-01-23 AU AU69923/91A patent/AU631960B2/en not_active Ceased
- 1991-01-23 MX MX2424791A patent/MX24247A/es unknown
- 1991-01-23 KR KR1019910001115A patent/KR910014378A/ko not_active Application Discontinuation
- 1991-01-23 NO NO91910267A patent/NO910267L/no unknown
- 1991-01-23 NZ NZ236868A patent/NZ236868A/en unknown
- 1991-01-24 EP EP91300539A patent/EP0439353B1/de not_active Expired - Lifetime
- 1991-01-24 HU HU91263A patent/HU208972B/hu not_active IP Right Cessation
- 1991-01-24 FI FI910365A patent/FI910365A/fi not_active Application Discontinuation
- 1991-01-24 JP JP3041442A patent/JPH04234880A/ja active Pending
- 1991-01-24 CN CN91100511A patent/CN1053611A/zh active Pending
- 1991-01-24 IE IE025191A patent/IE910251A1/en unknown
- 1991-01-24 YU YU12191A patent/YU12191A/sh unknown
- 1991-01-24 RU SU914894298A patent/RU1825365C/ru active
- 1991-01-24 DE DE69118933T patent/DE69118933T2/de not_active Expired - Fee Related
- 1991-01-24 ES ES91300539T patent/ES2087240T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU631960B2 (en) | 1992-12-10 |
| CN1053611A (zh) | 1991-08-07 |
| HU208972B (en) | 1994-02-28 |
| EP0439353A1 (de) | 1991-07-31 |
| PT96531A (pt) | 1991-10-15 |
| FI910365A (fi) | 1991-07-27 |
| RU1825365C (ru) | 1993-06-30 |
| ZA91428B (en) | 1992-09-30 |
| IL96979A0 (en) | 1992-03-29 |
| YU12191A (sh) | 1994-01-20 |
| CA2034592C (en) | 2001-06-05 |
| IE910251A1 (en) | 1991-07-31 |
| EP0439353B1 (de) | 1996-04-24 |
| HUT57207A (en) | 1991-11-28 |
| MX24247A (es) | 1993-11-01 |
| NZ236868A (en) | 1992-04-28 |
| NO910267D0 (no) | 1991-01-23 |
| ES2087240T3 (es) | 1996-07-16 |
| JPH04234880A (ja) | 1992-08-24 |
| CA2034592A1 (en) | 1991-07-27 |
| FI910365A0 (fi) | 1991-01-24 |
| DE69118933T2 (de) | 1996-10-02 |
| AU6992391A (en) | 1991-08-01 |
| KR910014378A (ko) | 1991-08-31 |
| NO910267L (no) | 1991-07-29 |
| HU910263D0 (en) | 1991-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |