HRP20000808A2 - Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c - Google Patents

Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c Download PDF

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Publication number
HRP20000808A2
HRP20000808A2 HR20000808A HRP20000808A HRP20000808A2 HR P20000808 A2 HRP20000808 A2 HR P20000808A2 HR 20000808 A HR20000808 A HR 20000808A HR P20000808 A HRP20000808 A HR P20000808A HR P20000808 A2 HRP20000808 A2 HR P20000808A2
Authority
HR
Croatia
Prior art keywords
ifn
peg
ribavirin
conjugate
treatment
Prior art date
Application number
HR20000808A
Other languages
English (en)
Croatian (hr)
Inventor
Friedrike Zahm
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8232086&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20000808(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HRP20000808A2 publication Critical patent/HRP20000808A2/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HR20000808A 1998-06-08 1999-05-29 Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c HRP20000808A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110433 1998-06-08
PCT/EP1999/003746 WO1999064016A1 (en) 1998-06-08 1999-05-29 Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c

Publications (1)

Publication Number Publication Date
HRP20000808A2 true HRP20000808A2 (en) 2001-10-31

Family

ID=8232086

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000808A HRP20000808A2 (en) 1998-06-08 1999-05-29 Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c

Country Status (34)

Country Link
US (3) US20030053986A1 (cg-RX-API-DMAC7.html)
EP (1) EP1087778B1 (cg-RX-API-DMAC7.html)
JP (2) JP3839667B2 (cg-RX-API-DMAC7.html)
KR (2) KR20050055053A (cg-RX-API-DMAC7.html)
CN (1) CN1170543C (cg-RX-API-DMAC7.html)
AR (1) AR019855A1 (cg-RX-API-DMAC7.html)
AT (1) ATE307597T1 (cg-RX-API-DMAC7.html)
AU (1) AU767131B2 (cg-RX-API-DMAC7.html)
BR (1) BR9911076A (cg-RX-API-DMAC7.html)
CA (1) CA2334267C (cg-RX-API-DMAC7.html)
CL (1) CL2010000828A1 (cg-RX-API-DMAC7.html)
CO (1) CO5050297A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ298681B6 (cg-RX-API-DMAC7.html)
DE (1) DE69927971T2 (cg-RX-API-DMAC7.html)
DK (1) DK1087778T3 (cg-RX-API-DMAC7.html)
ES (1) ES2251196T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20000808A2 (cg-RX-API-DMAC7.html)
HU (1) HU228218B1 (cg-RX-API-DMAC7.html)
ID (1) ID29285A (cg-RX-API-DMAC7.html)
IL (2) IL139786A0 (cg-RX-API-DMAC7.html)
MA (1) MA26641A1 (cg-RX-API-DMAC7.html)
MY (1) MY124091A (cg-RX-API-DMAC7.html)
NO (1) NO325598B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ508249A (cg-RX-API-DMAC7.html)
PE (1) PE20000560A1 (cg-RX-API-DMAC7.html)
PL (1) PL192364B1 (cg-RX-API-DMAC7.html)
RS (1) RS50144B (cg-RX-API-DMAC7.html)
RU (1) RU2271217C2 (cg-RX-API-DMAC7.html)
SA (1) SA99200208B1 (cg-RX-API-DMAC7.html)
SI (1) SI1087778T1 (cg-RX-API-DMAC7.html)
TR (1) TR200003635T2 (cg-RX-API-DMAC7.html)
TW (1) TWI241913B (cg-RX-API-DMAC7.html)
WO (1) WO1999064016A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200006814B (cg-RX-API-DMAC7.html)

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ATE307597T1 (de) 2005-11-15
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TR200003635T2 (tr) 2001-04-20
NO20006178D0 (no) 2000-12-05
JP3839667B2 (ja) 2006-11-01
SI1087778T1 (sl) 2006-02-28
PE20000560A1 (es) 2000-07-05
CO5050297A1 (es) 2001-06-27
RU2271217C2 (ru) 2006-03-10
HK1037981A1 (en) 2002-03-01
PL344794A1 (en) 2001-11-19
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IL139786A0 (en) 2002-02-10
US20030053986A1 (en) 2003-03-20
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US20070196385A1 (en) 2007-08-23
NO20006178L (no) 2000-12-05
CA2334267C (en) 2009-02-17
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MA26641A1 (fr) 2004-12-20
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EP1087778A1 (en) 2001-04-04
CZ298681B6 (cs) 2007-12-19
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