HRP20000618B1 - Liquid polymeric compositions for controlled release of bioactive substances - Google Patents

Liquid polymeric compositions for controlled release of bioactive substances

Info

Publication number
HRP20000618B1
HRP20000618B1 HR20000618A HRP20000618A HRP20000618B1 HR P20000618 B1 HRP20000618 B1 HR P20000618B1 HR 20000618 A HR20000618 A HR 20000618A HR P20000618 A HRP20000618 A HR P20000618A HR P20000618 B1 HRP20000618 B1 HR P20000618B1
Authority
HR
Croatia
Prior art keywords
controlled release
polymeric compositions
bioactive substances
liquid polymeric
solvent
Prior art date
Application number
HR20000618A
Other languages
English (en)
Croatian (hr)
Inventor
Rey Chern T.
Joel Zingerman R.
Original Assignee
Merck Sharp & Dohme Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815801.7A external-priority patent/GB9815801D0/en
Application filed by Merck Sharp & Dohme Corp. filed Critical Merck Sharp & Dohme Corp.
Publication of HRP20000618A2 publication Critical patent/HRP20000618A2/hr
Publication of HRP20000618B1 publication Critical patent/HRP20000618B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
HR20000618A 1998-03-19 1999-03-18 Liquid polymeric compositions for controlled release of bioactive substances HRP20000618B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7957498P 1998-03-19 1998-03-19
GBGB9815801.7A GB9815801D0 (en) 1998-07-21 1998-07-21 Liquid polymeric compositions for controlled released bioactive substances
PCT/US1999/005938 WO1999047073A1 (en) 1998-03-19 1999-03-18 Liquid polymeric compositions for controlled release of bioactive substances

Publications (2)

Publication Number Publication Date
HRP20000618A2 HRP20000618A2 (en) 2001-08-31
HRP20000618B1 true HRP20000618B1 (en) 2010-10-31

Family

ID=26314072

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000618A HRP20000618B1 (en) 1998-03-19 1999-03-18 Liquid polymeric compositions for controlled release of bioactive substances

Country Status (29)

Country Link
EP (2) EP1063942B1 (cs)
KR (1) KR100684055B1 (cs)
CN (1) CN1263435C (cs)
AT (1) ATE269676T1 (cs)
AU (1) AU745841B2 (cs)
BG (1) BG64782B1 (cs)
BR (1) BRPI9908893B8 (cs)
CA (1) CA2324265C (cs)
CY (1) CY1111669T1 (cs)
CZ (1) CZ300822B6 (cs)
DE (1) DE69918275T2 (cs)
DK (1) DK1063942T3 (cs)
EA (1) EA003460B1 (cs)
EE (1) EE04216B1 (cs)
ES (1) ES2222694T3 (cs)
HR (1) HRP20000618B1 (cs)
HU (1) HU226711B1 (cs)
ID (1) ID25808A (cs)
IL (2) IL137982A0 (cs)
IS (1) IS2221B (cs)
ME (1) ME00867B (cs)
NO (1) NO329589B1 (cs)
NZ (1) NZ506415A (cs)
PL (1) PL192270B1 (cs)
PT (1) PT1063942E (cs)
SI (1) SI1063942T1 (cs)
SK (1) SK286612B6 (cs)
TR (1) TR200002685T2 (cs)
WO (1) WO1999047073A1 (cs)

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US6340672B1 (en) * 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation
NZ523385A (en) * 2000-06-28 2005-09-30 Atul J Biodegradable vehicles and BAS-loaded delivery systems for use as biodegradable fillers and/or spacers, e.g. artificial skin
EP1317304B1 (en) * 2000-09-01 2011-04-27 Palmaya Pty Ltd. Slow release pharmaceutical preparation and method of administering same
EP1372729B1 (en) * 2001-02-23 2009-04-08 Genentech, Inc. Erodible polymers for injection
JP5170935B2 (ja) * 2001-11-14 2013-03-27 デュレクト コーポレーション 注入可能なデポー組成物
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
WO2004103342A2 (en) * 2003-05-16 2004-12-02 Alkermes Controlled Therapeutics, Inc. Injectable sustained release compositions
CN1293921C (zh) * 2003-08-18 2007-01-10 王玉万 含乙基纤维素和脂肪酸酯类的长效注射剂
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
TWI369218B (en) * 2004-12-14 2012-08-01 Novartis Ag In situ forming implant for animals
US8362086B2 (en) * 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
TW200924647A (en) * 2007-08-30 2009-06-16 Schering Plough Ltd Local topical administration formulations containing fipronil
BRPI0705822A2 (pt) * 2007-10-25 2009-06-23 Schering Plough Saude Animal Ltda formulação injetável com ação prolongada e uso de um agente semi-sintético derivado do grupo das avermectinas, em combinação com um polìmero biodegradável
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
US20090281150A1 (en) * 2008-04-09 2009-11-12 Nicola Frances Bateman Compound 249
BRPI0802255A2 (pt) * 2008-06-17 2010-03-16 Sespo Ind E Com Ltda composição de uso tópico para controle de ectoparasitos em cães e gatos
US12171463B2 (en) 2008-10-03 2024-12-24 Femasys Inc. Contrast agent generation and injection system for sonographic imaging
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
EP2416663A2 (en) 2009-03-18 2012-02-15 Martin Benedict George Donnelly Parasiticidal formulation
DE102011114986A1 (de) * 2011-09-28 2013-03-28 Ethris Gmbh Sprühsystem
CA2931547A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
US8785426B1 (en) 2013-12-13 2014-07-22 Upsher-Smith Laboratories, Inc. Testosterone gel compositions and related methods
CN107811967B (zh) * 2016-09-09 2021-08-24 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) 抗寄生虫药物原位固化缓释注射剂及其制备方法
KR102101969B1 (ko) 2017-09-06 2020-04-22 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이의 제조 방법
WO2019050259A1 (ko) * 2017-09-06 2019-03-14 (주)인벤티지랩 목시덱틴을 포함하는 마이크로 입자 및 이의 제조 방법
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CN111675778B (zh) * 2020-06-15 2021-11-02 苏州大学 基于pisa方法制备的偶氮还原酶响应性的近红外聚合物荧光探针及其应用
ES3032945T3 (en) 2020-11-19 2025-07-29 Fis Fabbrica Italiana Sintetici Spa Process for the preparation of trenbolone acetate having a definite particle size distribution and a irregular hexagon plates crystal habit
ES2948624T3 (es) 2020-11-19 2023-09-14 Fis Fabbrica Italiana Sintetici Spa Proceso mejorado para la preparación de trembolona y/o acetato de trembolona
EP4000688B1 (en) 2020-11-19 2025-11-05 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of trenbolone acetate having a definite particle size distribution
CN116940358A (zh) 2021-01-12 2023-10-24 度勒科特公司 持续释放药物递送系统和有关的方法

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US4150108A (en) * 1975-12-29 1979-04-17 Graham Neil B Injectable medicinal compositions
US4329332A (en) * 1978-07-19 1982-05-11 Patrick Couvreur Biodegradable submicroscopic particles containing a biologically active substance and compositions containing them
US4489055A (en) * 1978-07-19 1984-12-18 N.V. Sopar S.A. Process for preparing biodegradable submicroscopic particles containing a biologically active substance and their use
US4333919A (en) * 1979-09-12 1982-06-08 Eli Lilly And Company Growth promotant controlled release formulations and method of treatment
US4331652A (en) * 1979-09-12 1982-05-25 Eli Lilly And Company Controlled release parasitic formulations and method
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
DE3378250D1 (en) * 1982-04-22 1988-11-24 Ici Plc Continuous release formulations
DE3400106A1 (de) * 1984-01-04 1985-07-11 Klaus-Dieter Dr. 3550 Marburg Bremecker Pharmazeutische zubereitungen mit gesteuerter arzneistoff-freisetzung
IT1250654B (it) * 1991-07-08 1995-04-21 Farcon Ag Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph.
AU2605592A (en) * 1991-10-15 1993-04-22 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
WO1994012159A1 (en) * 1992-11-30 1994-06-09 Pfizer Inc. Supported liquid membrane delivery devices

Also Published As

Publication number Publication date
CA2324265A1 (en) 1999-09-23
EP1484033A1 (en) 2004-12-08
NO20004616L (no) 2000-09-15
EP1063942B1 (en) 2004-06-23
ATE269676T1 (de) 2004-07-15
KR20010041987A (ko) 2001-05-25
BRPI9908893B8 (pt) 2021-05-25
PL192270B1 (pl) 2006-09-29
WO1999047073A1 (en) 1999-09-23
TR200002685T2 (tr) 2000-12-21
BR9908893A (pt) 2000-11-28
NZ506415A (en) 2003-06-30
IL137982A (en) 2006-10-05
CZ300822B6 (cs) 2009-08-19
IS2221B (is) 2007-03-15
SK286612B6 (sk) 2009-02-05
HUP0102385A3 (en) 2002-12-28
EA200000964A1 (ru) 2001-02-26
SI1063942T1 (en) 2004-10-31
DE69918275D1 (de) 2004-07-29
BG64782B1 (bg) 2006-04-28
ME00867B (me) 2008-08-07
BR9908893B1 (pt) 2013-11-19
IL137982A0 (en) 2001-10-31
CN1263435C (zh) 2006-07-12
HUP0102385A2 (hu) 2002-03-28
AU3010099A (en) 1999-10-11
CY1111669T1 (el) 2015-10-07
CA2324265C (en) 2008-08-05
ES2222694T3 (es) 2005-02-01
SK13752000A3 (sk) 2001-03-12
CN1293553A (zh) 2001-05-02
NO20004616D0 (no) 2000-09-15
KR100684055B1 (ko) 2007-02-16
EP1063942A4 (en) 2002-07-10
BG104838A (en) 2001-07-31
EE200000539A (et) 2002-02-15
IS5599A (is) 2000-08-22
EE04216B1 (et) 2004-02-16
EP1063942A1 (en) 2001-01-03
ID25808A (id) 2000-11-09
EP1484033B1 (en) 2011-02-23
HU226711B1 (en) 2009-07-28
EA003460B1 (ru) 2003-06-26
HRP20000618A2 (en) 2001-08-31
HK1036579A1 (zh) 2002-01-11
DE69918275T2 (de) 2005-07-07
CZ20003420A3 (en) 2001-05-16
DK1063942T3 (da) 2005-11-07
HK1031990A1 (en) 2001-07-06
NO329589B1 (no) 2010-11-15
PL342858A1 (en) 2001-07-16
AU745841B2 (en) 2002-04-11
PT1063942E (pt) 2004-10-29

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: MERCK SHARP & DOHME CORP., US

B1PR Patent granted
PNAN Change of the applicant name, address/residence

Owner name: MERCK SHARP & DOHME CORP., US

Owner name: SCHERING CORPORATION, US

ODRP Renewal fee for the maintenance of a patent

Payment date: 20180313

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20190318