ATE211647T1 - Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel - Google Patents
Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittelInfo
- Publication number
- ATE211647T1 ATE211647T1 AT95202770T AT95202770T ATE211647T1 AT E211647 T1 ATE211647 T1 AT E211647T1 AT 95202770 T AT95202770 T AT 95202770T AT 95202770 T AT95202770 T AT 95202770T AT E211647 T1 ATE211647 T1 AT E211647T1
- Authority
- AT
- Austria
- Prior art keywords
- water
- pharmaceutical composition
- solid pharmaceutical
- composition containing
- binding agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94203017 | 1994-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE211647T1 true ATE211647T1 (de) | 2002-01-15 |
Family
ID=8217284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95202770T ATE211647T1 (de) | 1994-10-17 | 1995-10-13 | Feste pharmazeutische zusammensetzung mit einem wasserbindenden hilfsmittel |
Country Status (20)
Country | Link |
---|---|
US (1) | US6187339B1 (de) |
EP (1) | EP0707848B1 (de) |
JP (1) | JPH08268914A (de) |
KR (1) | KR100388932B1 (de) |
CN (1) | CN1112185C (de) |
AT (1) | ATE211647T1 (de) |
AU (1) | AU688581B2 (de) |
BR (1) | BR9504400A (de) |
CA (1) | CA2159419C (de) |
DE (1) | DE69524917T2 (de) |
DK (1) | DK0707848T3 (de) |
ES (1) | ES2171498T3 (de) |
FI (1) | FI117121B (de) |
HK (1) | HK1001886A1 (de) |
HU (1) | HU221427B (de) |
IL (1) | IL115445A (de) |
MX (1) | MX9504252A (de) |
PT (1) | PT707848E (de) |
RU (1) | RU2152802C2 (de) |
TR (1) | TR199501246A2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2159419C (en) * | 1994-10-17 | 2006-07-04 | Pieter De Haan | Solid pharmaceutical composition comprising an excipient capable of binding water |
IL123984A (en) | 1997-04-22 | 2004-09-27 | Akzo Nobel Nv | Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable |
IL128818A0 (en) * | 1998-03-12 | 2000-01-31 | Akzo Nobel Nv | Making dosage units using low shear granulation |
EP0955048A1 (de) * | 1998-03-12 | 1999-11-10 | Akzo Nobel N.V. | Herstellung von Dosiereinheiten unter Anwendung einer Granulierung mit geringer Scherbeanspruchung |
AU763232B2 (en) * | 1998-10-16 | 2003-07-17 | Merck Sharp & Dohme B.V. | High purity composition comprising (7alpha,17alpha)- 17-hydroxy- 7-methyl- 19-nor-17-pregn- 5(10)-en-20-yn-3-one |
AU5209600A (en) * | 1999-04-06 | 2000-10-23 | Akzo Nobel N.V. | Orally active androgens |
US6855333B1 (en) * | 2000-10-03 | 2005-02-15 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid thyroid drug formulations |
US6979462B1 (en) * | 2000-10-03 | 2005-12-27 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid drug formulations |
FR2824477B1 (fr) * | 2001-05-09 | 2005-09-09 | Ethypharm Lab Prod Ethiques | Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes |
US6933380B2 (en) | 2001-10-19 | 2005-08-23 | Yung-Zip Chemical Ind. Co., Ltd. | Excipients containing low residual solvent and method for producing the same |
DE10159120B4 (de) * | 2001-12-01 | 2006-08-17 | Lts Lohmann Therapie-Systeme Ag | Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung |
IS6633A (is) * | 2002-11-22 | 2004-05-23 | Omega Farma Ehf. | Samsetningar af fínasteríð töflum |
EP1634908B1 (de) | 2003-05-30 | 2017-01-11 | Asahi Kasei Kabushiki Kaisha | Cellulosepulver |
CA2533013C (en) * | 2003-07-17 | 2011-07-26 | Banner Pharmacaps, Inc. | Controlled release preparations |
DE102004059880A1 (de) * | 2004-12-10 | 2006-06-14 | Grünenthal GmbH | Stabiles, hormonhaltiges (Zwischen-)Produkt |
US20100184785A1 (en) * | 2007-06-06 | 2010-07-22 | Basf Se | Pharmaceutical formulation for the production of chewable tablets and lozenges |
CN101707930B (zh) * | 2007-06-06 | 2013-10-30 | 巴斯夫欧洲公司 | 用于制备快速崩解的片剂的药物配制剂 |
CZ300465B6 (cs) * | 2007-07-25 | 2009-05-27 | Zentiva, A. S. | Zpusob výroby komprimované farmaceutické formulace s obsahem tibolonu |
DE102009012788A1 (de) * | 2009-03-13 | 2010-09-30 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Verpressbares Tablettenmaterial mit ölhaltigem Wirkstoff, Tablette sowie Verfahren und Vorrichtung zu deren Herstellung |
HUP0900698A2 (en) | 2009-11-06 | 2011-06-28 | Richter Gedeon Nyrt | Pharmaceutical compositions of enhanced stability containing drospirenone and ethynyl estradiol and process for their preparation |
DE102011010437A1 (de) * | 2011-02-04 | 2012-08-09 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Tablettierhilfsmittel |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
PT2782584T (pt) | 2011-11-23 | 2021-09-02 | Therapeuticsmd Inc | Preparações e terapias de substituição para hormonoterapias naturais combinadas |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然の併用ホルモン補充療法剤及び療法 |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2195893A (en) * | 1938-07-28 | 1940-04-02 | Nellie C Mcgann | Two-part support clamp |
US2965541A (en) * | 1959-06-22 | 1960-12-20 | Upjohn Co | 17alpha-acetoxyprogesterone compositions for oral use and methods of using same |
US3568828A (en) * | 1967-03-01 | 1971-03-09 | Squibb & Sons Inc | Modified sequential oral contraceptive |
NL7506407A (nl) * | 1975-05-30 | 1976-12-02 | Akzo Nv | Werkwijze ter bereiding van een oraal werkzaam far- maceutisch preparaat. |
JPS57142911A (en) * | 1981-02-28 | 1982-09-03 | Furointo Sangyo Kk | Absorption-improving agent |
JPS57165392A (en) * | 1981-04-06 | 1982-10-12 | Toyo Jozo Co Ltd | Long-acting cephalexin tablet |
US4544554A (en) * | 1983-09-26 | 1985-10-01 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
JPS60224616A (ja) * | 1984-04-24 | 1985-11-09 | Teijin Ltd | 経鼻投与用組成物 |
FR2571045B1 (fr) * | 1984-10-03 | 1987-12-11 | Roquette Freres | Mannitol granulaire directement compressible et son procede de fabrication |
DE68916983T2 (de) * | 1988-02-25 | 1995-01-19 | Yamanouchi Europ Bv | Verfahren zur Herstellung eines pharmazeutischen Granulats. |
US5169645A (en) * | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
DE69013689T2 (de) * | 1990-11-29 | 1995-03-02 | Wei Ming Pharmaceutical Mfg Co | Hilfsträger für direkte Verpressung. |
IE71203B1 (en) * | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
IE62665B1 (en) * | 1990-12-17 | 1995-02-22 | Akzo Nv | Contraceptive regimen |
US5179122A (en) * | 1991-02-11 | 1993-01-12 | Eastman Kodak Company | Nutritional supplement containing vitamin e |
IE67345B1 (en) * | 1991-03-12 | 1996-03-20 | Akzo Nv | Low dose dry pharmaceutical preparations |
IT1256386B (it) * | 1992-11-13 | 1995-12-04 | Luigi Boltri | Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo |
BE1006990A5 (nl) * | 1993-04-22 | 1995-02-07 | Univ Gent | Werkwijze en samenstelling om een aktief bestanddeel in een vaste toedieningsvorm te brengen. |
CN1133005A (zh) * | 1993-09-03 | 1996-10-09 | 史密丝克莱恩比彻姆公司 | 稳定的片剂 |
CA2159419C (en) * | 1994-10-17 | 2006-07-04 | Pieter De Haan | Solid pharmaceutical composition comprising an excipient capable of binding water |
US6057139A (en) * | 1995-06-29 | 2000-05-02 | Mcneil-Ppc, Inc. | Preblend of microcrystalline cellulose and lactase for making tablets |
US5801220A (en) * | 1995-11-01 | 1998-09-01 | E.R. Squibb & Sons, Inc. | Rapidly disintegrating thickening composition |
US5800834A (en) * | 1996-06-10 | 1998-09-01 | Spireas; Spiridon | Liquisolid systems and methods of preparing same |
US6096337A (en) * | 1996-06-10 | 2000-08-01 | Spireas; Spiridon | Liquisolid systems and methods of preparing same |
DE19628617A1 (de) * | 1996-07-16 | 1998-01-22 | Basf Ag | Direkttablettierhilfsmittel |
-
1995
- 1995-09-28 CA CA002159419A patent/CA2159419C/en not_active Expired - Fee Related
- 1995-09-28 IL IL11544595A patent/IL115445A/xx not_active IP Right Cessation
- 1995-10-06 MX MX9504252A patent/MX9504252A/es not_active IP Right Cessation
- 1995-10-12 TR TR95/01246A patent/TR199501246A2/xx unknown
- 1995-10-12 KR KR1019950035039A patent/KR100388932B1/ko not_active IP Right Cessation
- 1995-10-13 PT PT95202770T patent/PT707848E/pt unknown
- 1995-10-13 DE DE69524917T patent/DE69524917T2/de not_active Expired - Lifetime
- 1995-10-13 AT AT95202770T patent/ATE211647T1/de not_active IP Right Cessation
- 1995-10-13 ES ES95202770T patent/ES2171498T3/es not_active Expired - Lifetime
- 1995-10-13 EP EP95202770A patent/EP0707848B1/de not_active Expired - Lifetime
- 1995-10-13 BR BR9504400A patent/BR9504400A/pt not_active IP Right Cessation
- 1995-10-13 DK DK95202770T patent/DK0707848T3/da active
- 1995-10-16 RU RU95118099/14A patent/RU2152802C2/ru not_active IP Right Cessation
- 1995-10-16 HU HU9502985A patent/HU221427B/hu not_active IP Right Cessation
- 1995-10-16 AU AU34267/95A patent/AU688581B2/en not_active Ceased
- 1995-10-16 FI FI954905A patent/FI117121B/fi active IP Right Grant
- 1995-10-16 CN CN95116176A patent/CN1112185C/zh not_active Expired - Fee Related
- 1995-10-17 US US08/544,042 patent/US6187339B1/en not_active Expired - Fee Related
- 1995-10-17 JP JP7268772A patent/JPH08268914A/ja active Pending
-
1998
- 1998-02-11 HK HK98101017A patent/HK1001886A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9504400A (pt) | 1997-05-27 |
EP0707848B1 (de) | 2002-01-09 |
CN1112185C (zh) | 2003-06-25 |
KR100388932B1 (ko) | 2003-09-19 |
RU2152802C2 (ru) | 2000-07-20 |
HU9502985D0 (en) | 1995-12-28 |
FI954905A0 (fi) | 1995-10-16 |
JPH08268914A (ja) | 1996-10-15 |
MX9504252A (es) | 1997-01-31 |
CA2159419A1 (en) | 1996-04-18 |
HU221427B (en) | 2002-10-28 |
IL115445A (en) | 1999-08-17 |
DE69524917T2 (de) | 2002-08-29 |
AU688581B2 (en) | 1998-03-12 |
PT707848E (pt) | 2002-06-28 |
TR199501246A2 (tr) | 1996-06-21 |
FI117121B (fi) | 2006-06-30 |
ES2171498T3 (es) | 2002-09-16 |
DK0707848T3 (da) | 2002-04-15 |
HUT75247A (en) | 1997-05-28 |
US6187339B1 (en) | 2001-02-13 |
KR960013373A (ko) | 1996-05-22 |
DE69524917D1 (de) | 2002-02-14 |
HK1001886A1 (en) | 1998-07-17 |
FI954905A (fi) | 1996-04-18 |
CN1130064A (zh) | 1996-09-04 |
AU3426795A (en) | 1996-05-02 |
EP0707848A1 (de) | 1996-04-24 |
IL115445A0 (en) | 1995-12-31 |
CA2159419C (en) | 2006-07-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |