HK84190A - 5-halovinyl-2'-deoxyuridine derivatives - Google Patents

5-halovinyl-2'-deoxyuridine derivatives

Info

Publication number
HK84190A
HK84190A HK841/90A HK84190A HK84190A HK 84190 A HK84190 A HK 84190A HK 841/90 A HK841/90 A HK 841/90A HK 84190 A HK84190 A HK 84190A HK 84190 A HK84190 A HK 84190A
Authority
HK
Hong Kong
Prior art keywords
halovinyl
deoxyuridine derivatives
deoxyuridine
derivatives
bromine
Prior art date
Application number
HK841/90A
Other languages
English (en)
Inventor
David Ian Carter Scopes
Roger Frank Newton
Paul Ravenscroft
Richard Clive Cookson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HK84190A publication Critical patent/HK84190A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04Saturated ethers
    • C07C43/13Saturated ethers containing hydroxy or O-metal groups
    • C07C43/135Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/08Saturated compounds containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HK841/90A 1982-09-17 1990-10-18 5-halovinyl-2'-deoxyuridine derivatives HK84190A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8226515 1982-09-17

Publications (1)

Publication Number Publication Date
HK84190A true HK84190A (en) 1990-10-25

Family

ID=10532974

Family Applications (1)

Application Number Title Priority Date Filing Date
HK841/90A HK84190A (en) 1982-09-17 1990-10-18 5-halovinyl-2'-deoxyuridine derivatives

Country Status (17)

Country Link
US (1) US4564618A (da)
EP (1) EP0104066B1 (da)
JP (1) JPS5980620A (da)
AT (1) ATE36325T1 (da)
AU (2) AU575022B2 (da)
CA (1) CA1257595A (da)
CZ (1) CZ402691A3 (da)
DE (1) DE3377647D1 (da)
DK (1) DK160271C (da)
ES (2) ES525670A0 (da)
GB (1) GB2129425B (da)
HK (1) HK84190A (da)
IE (1) IE55921B1 (da)
MX (1) MX9203234A (da)
NZ (1) NZ205619A (da)
SG (1) SG68890G (da)
ZA (1) ZA836902B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719214A (en) * 1985-07-25 1988-01-12 Southern Research Institute Carbocyclic analogues of thymine nucleosides
KR870002141A (ko) * 1985-08-16 1987-03-30 배리 안토니 뉴샘 구아닌 유도체의 제조 방법 및 이 유도체를 함유하는 제약 조성물
EP0516186A3 (en) * 1987-04-16 1993-01-13 Medivir Aktiebolag Nucleosides and nucleoside analogues, pharmaceutical composition and processes for the preparation of the compounds
US5215970A (en) * 1987-04-16 1993-06-01 Medivir Ab Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) * 1987-05-11 1989-09-05 Merck & Co., Inc. 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
GB8920457D0 (en) * 1989-09-11 1989-10-25 Glaxo Group Ltd Chemical compounds
USH1142H (en) 1990-11-05 1993-02-02 Optically active cyclobutyl pyrimidine

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS606943B2 (ja) * 1975-04-01 1985-02-21 三井製薬工業株式会社 1−(α−アルコキシアルキル)−ウラシル類の製造法
US4232154A (en) * 1977-12-13 1980-11-04 United States Of America Carbocyclic analogs of cytosine nucleosides exhibiting antiviral and antineoplasticactivity
US4177348A (en) * 1977-12-13 1979-12-04 United States Government Carbocyclic analogs of cytosine nucleosides
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions
EP0072137A1 (en) * 1981-08-01 1983-02-16 Beecham Group Plc Antiviral deoxyuridine compounds
US4396623A (en) * 1981-08-26 1983-08-02 Southern Research Institute Carbocyclic analogs of uracil nucleosides as antiviral agents
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof
JPS5843993A (ja) * 1981-09-09 1983-03-14 Yamasa Shoyu Co Ltd 1−β−D−アラビノフラノシル−(E)−5−(2−ハロゲノビニル)ウラシル−5′−りん酸およびその製造法
EP0080305A1 (en) * 1981-11-19 1983-06-01 Beecham Group Plc Antiviral 2'-deoxyuridines, their preparation and use
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
DE3620646A1 (de) * 1986-06-20 1987-12-23 Bayer Ag Verfahren zur herstellung von (1r, 4s)-4-hydroxy-2-cyclopentenylestern

Also Published As

Publication number Publication date
AU1646588A (en) 1988-08-11
CA1271199C (da) 1990-07-03
US4564618A (en) 1986-01-14
IE832175L (en) 1984-03-17
DK160271C (da) 1991-07-22
GB2129425B (en) 1987-02-11
ES8502978A1 (es) 1985-02-01
DE3377647D1 (de) 1988-09-15
ATE36325T1 (de) 1988-08-15
DK422183A (da) 1984-03-18
DK160271B (da) 1991-02-18
EP0104066B1 (en) 1988-08-10
AU575022B2 (en) 1988-07-21
CZ402691A3 (en) 1993-07-14
AU1918583A (en) 1984-03-22
ES532056A0 (es) 1985-08-01
SG68890G (en) 1990-10-26
IE55921B1 (en) 1991-02-27
GB8324813D0 (en) 1983-10-19
GB2129425A (en) 1984-05-16
JPS5980620A (ja) 1984-05-10
ES525670A0 (es) 1985-02-01
ES8506751A1 (es) 1985-08-01
MX9203234A (es) 1992-07-01
ZA836902B (en) 1985-05-29
EP0104066A3 (en) 1984-06-06
DK422183D0 (da) 1983-09-16
AU601583B2 (en) 1990-09-13
NZ205619A (en) 1987-09-30
EP0104066A2 (en) 1984-03-28
CA1257595A (en) 1989-07-18

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