DK422183D0 - Fremgangsmade til fremstilling af 5-halogenvinyl-2' -deoxyuridinderivater - Google Patents
Fremgangsmade til fremstilling af 5-halogenvinyl-2' -deoxyuridinderivaterInfo
- Publication number
- DK422183D0 DK422183D0 DK4221/83A DK422183A DK422183D0 DK 422183 D0 DK422183 D0 DK 422183D0 DK 4221/83 A DK4221/83 A DK 4221/83A DK 422183 A DK422183 A DK 422183A DK 422183 D0 DK422183 D0 DK 422183D0
- Authority
- DK
- Denmark
- Prior art keywords
- ingrediates
- halogenvinyl
- deoxyuride
- preparing
- procedure
- Prior art date
Links
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/13—Saturated ethers containing hydroxy or O-metal groups
- C07C43/135—Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/08—Saturated compounds containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8226515 | 1982-09-17 | ||
| GB8226515 | 1982-09-17 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK422183D0 true DK422183D0 (da) | 1983-09-16 |
| DK422183A DK422183A (da) | 1984-03-18 |
| DK160271B DK160271B (da) | 1991-02-18 |
| DK160271C DK160271C (da) | 1991-07-22 |
Family
ID=10532974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK422183A DK160271C (da) | 1982-09-17 | 1983-09-16 | Analogifremgangsmaade til fremstilling af 5-halogenvinyl-uracil-derivater |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4564618A (da) |
| EP (1) | EP0104066B1 (da) |
| JP (1) | JPS5980620A (da) |
| AT (1) | ATE36325T1 (da) |
| AU (2) | AU575022B2 (da) |
| CA (1) | CA1257595A (da) |
| CZ (1) | CZ402691A3 (da) |
| DE (1) | DE3377647D1 (da) |
| DK (1) | DK160271C (da) |
| ES (2) | ES525670A0 (da) |
| GB (1) | GB2129425B (da) |
| HK (1) | HK84190A (da) |
| IE (1) | IE55921B1 (da) |
| MX (1) | MX9203234A (da) |
| NZ (1) | NZ205619A (da) |
| SG (1) | SG68890G (da) |
| ZA (1) | ZA836902B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4719214A (en) * | 1985-07-25 | 1988-01-12 | Southern Research Institute | Carbocyclic analogues of thymine nucleosides |
| KR870002141A (ko) * | 1985-08-16 | 1987-03-30 | 배리 안토니 뉴샘 | 구아닌 유도체의 제조 방법 및 이 유도체를 함유하는 제약 조성물 |
| EP0516186A3 (en) * | 1987-04-16 | 1993-01-13 | Medivir Aktiebolag | Nucleosides and nucleoside analogues, pharmaceutical composition and processes for the preparation of the compounds |
| US5215970A (en) * | 1987-04-16 | 1993-06-01 | Medivir Ab | Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds |
| US4863927A (en) * | 1987-05-11 | 1989-09-05 | Merck & Co., Inc. | 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils |
| GB8920457D0 (en) * | 1989-09-11 | 1989-10-25 | Glaxo Group Ltd | Chemical compounds |
| USH1142H (en) | 1990-11-05 | 1993-02-02 | Optically active cyclobutyl pyrimidine |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS606943B2 (ja) * | 1975-04-01 | 1985-02-21 | 三井製薬工業株式会社 | １−（α−アルコキシアルキル）−ウラシル類の製造法 |
| US4177348A (en) * | 1977-12-13 | 1979-12-04 | United States Government | Carbocyclic analogs of cytosine nucleosides |
| US4232154A (en) * | 1977-12-13 | 1980-11-04 | United States Of America | Carbocyclic analogs of cytosine nucleosides exhibiting antiviral and antineoplasticactivity |
| GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
| GB2060604B (en) * | 1979-10-03 | 1983-11-23 | Univ Birmingham And Stichting | E15-(2-halogenovinyl)-2'-deoxycytidines |
| JPS5738774A (en) * | 1980-08-19 | 1982-03-03 | Chugai Pharmaceut Co Ltd | Uracil derivative and its preparation |
| US4347360A (en) * | 1980-09-16 | 1982-08-31 | Ens Bio Logicals Inc. | Ring open nucleoside analogues |
| NZ199764A (en) * | 1981-03-20 | 1984-08-24 | Beecham Group Plc | 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions |
| EP0072137A1 (en) * | 1981-08-01 | 1983-02-16 | Beecham Group Plc | Antiviral deoxyuridine compounds |
| US4396623A (en) * | 1981-08-26 | 1983-08-02 | Southern Research Institute | Carbocyclic analogs of uracil nucleosides as antiviral agents |
| HU183567B (en) * | 1981-09-07 | 1984-05-28 | Mta Koezponti Kemiai Kutato In | Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof |
| JPS5843993A (ja) * | 1981-09-09 | 1983-03-14 | Yamasa Shoyu Co Ltd | １−β−Ｄ−アラビノフラノシル−（Ｅ）−５−（２−ハロゲノビニル）ウラシル−５′−りん酸およびその製造法 |
| EP0080305A1 (en) * | 1981-11-19 | 1983-06-01 | Beecham Group Plc | Antiviral 2'-deoxyuridines, their preparation and use |
| EP0082668A1 (en) * | 1981-12-18 | 1983-06-29 | Beecham Group Plc | 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections |
| DE3620646A1 (de) * | 1986-06-20 | 1987-12-23 | Bayer Ag | Verfahren zur herstellung von (1r, 4s)-4-hydroxy-2-cyclopentenylestern |
-
1983
- 1983-09-16 CA CA000436838A patent/CA1257595A/en not_active Expired
- 1983-09-16 EP EP83305456A patent/EP0104066B1/en not_active Expired
- 1983-09-16 JP JP58169516A patent/JPS5980620A/ja active Pending
- 1983-09-16 US US06/532,859 patent/US4564618A/en not_active Expired - Fee Related
- 1983-09-16 NZ NZ205619A patent/NZ205619A/en unknown
- 1983-09-16 AU AU19185/83A patent/AU575022B2/en not_active Ceased
- 1983-09-16 IE IE2175/83A patent/IE55921B1/en not_active IP Right Cessation
- 1983-09-16 AT AT83305456T patent/ATE36325T1/de not_active IP Right Cessation
- 1983-09-16 DE DE8383305456T patent/DE3377647D1/de not_active Expired
- 1983-09-16 ES ES525670A patent/ES525670A0/es active Granted
- 1983-09-16 DK DK422183A patent/DK160271C/da not_active IP Right Cessation
- 1983-09-16 ZA ZA836902A patent/ZA836902B/xx unknown
- 1983-09-16 GB GB08324813A patent/GB2129425B/en not_active Expired
-
1984
- 1984-04-30 ES ES532056A patent/ES8506751A1/es not_active Expired
-
1988
- 1988-05-17 AU AU16465/88A patent/AU601583B2/en not_active Ceased
-
1990
- 1990-08-20 SG SG688/90A patent/SG68890G/en unknown
- 1990-10-18 HK HK841/90A patent/HK84190A/xx unknown
-
1991
- 1991-12-23 CZ CS914026A patent/CZ402691A3/cs unknown
-
1992
- 1992-06-24 MX MX9203234A patent/MX9203234A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2129425A (en) | 1984-05-16 |
| SG68890G (en) | 1990-10-26 |
| CA1257595A (en) | 1989-07-18 |
| DK160271C (da) | 1991-07-22 |
| ZA836902B (en) | 1985-05-29 |
| DK160271B (da) | 1991-02-18 |
| AU575022B2 (en) | 1988-07-21 |
| EP0104066A2 (en) | 1984-03-28 |
| MX9203234A (es) | 1992-07-01 |
| ES8502978A1 (es) | 1985-02-01 |
| GB8324813D0 (en) | 1983-10-19 |
| ATE36325T1 (de) | 1988-08-15 |
| EP0104066A3 (en) | 1984-06-06 |
| JPS5980620A (ja) | 1984-05-10 |
| CZ402691A3 (en) | 1993-07-14 |
| AU1918583A (en) | 1984-03-22 |
| DE3377647D1 (de) | 1988-09-15 |
| HK84190A (en) | 1990-10-25 |
| AU1646588A (en) | 1988-08-11 |
| AU601583B2 (en) | 1990-09-13 |
| ES532056A0 (es) | 1985-08-01 |
| CA1271199C (da) | 1990-07-03 |
| IE55921B1 (en) | 1991-02-27 |
| DK422183A (da) | 1984-03-18 |
| EP0104066B1 (en) | 1988-08-10 |
| ES8506751A1 (es) | 1985-08-01 |
| ES525670A0 (es) | 1985-02-01 |
| NZ205619A (en) | 1987-09-30 |
| IE832175L (en) | 1984-03-17 |
| US4564618A (en) | 1986-01-14 |
| GB2129425B (en) | 1987-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |