HK6177A - Heterocyclic azaspiroalkanediones - Google Patents

Heterocyclic azaspiroalkanediones

Info

Publication number
HK6177A
HK6177A HK61/77A HK6177A HK6177A HK 6177 A HK6177 A HK 6177A HK 61/77 A HK61/77 A HK 61/77A HK 6177 A HK6177 A HK 6177A HK 6177 A HK6177 A HK 6177A
Authority
HK
Hong Kong
Prior art keywords
azaspiroalkanediones
heterocyclic
heterocyclic azaspiroalkanediones
Prior art date
Application number
HK61/77A
Other languages
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HK6177A publication Critical patent/HK6177A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK61/77A 1969-11-24 1977-01-27 Heterocyclic azaspiroalkanediones HK6177A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00879604A US3717634A (en) 1969-11-24 1969-11-24 N-(heteroarcyclic)piperazinylalkyl-azaspiroalkanediones

Publications (1)

Publication Number Publication Date
HK6177A true HK6177A (en) 1977-02-04

Family

ID=25374483

Family Applications (1)

Application Number Title Priority Date Filing Date
HK61/77A HK6177A (en) 1969-11-24 1977-01-27 Heterocyclic azaspiroalkanediones

Country Status (14)

Country Link
US (2) US3717634A (xx)
BE (1) BE759371A (xx)
CH (2) CH552608A (xx)
CY (1) CY886A (xx)
DE (1) DE2057845A1 (xx)
DK (1) DK141753B (xx)
ES (1) ES530335A0 (xx)
FR (1) FR2073406B1 (xx)
GB (1) GB1332194A (xx)
HK (1) HK6177A (xx)
KE (1) KE2691A (xx)
MY (1) MY7700151A (xx)
NL (1) NL7017031A (xx)
ZA (1) ZA707826B (xx)

Families Citing this family (129)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4123538A (en) * 1977-08-30 1978-10-31 Mcneil Laboratories, Incorporated (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4261990A (en) * 1979-03-09 1981-04-14 Ciba-Geigy Corporation N-alkyleneiminoalkyl-dicarboximides as antiallergics and antiasthmatics
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4351939A (en) * 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
US4417049A (en) * 1980-10-16 1983-11-22 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
CA1172255A (en) * 1980-12-11 1984-08-07 Robert R. Covington Buspirone process
US4320131A (en) * 1981-03-16 1982-03-16 Mead Johnson & Company N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
US4409223A (en) * 1982-08-06 1983-10-11 Riblet Leslie A Anxiolytic method
US4515947A (en) * 1982-08-11 1985-05-07 Eastman Kodak Company Cyanoalkylpiperazines and methods for their preparation and use
US4620002A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company 2-pyrimidyl alkanesulfonates
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
US4438119A (en) 1982-12-23 1984-03-20 Mead Johnson & Company Method for alleviation of extrapyramidal motor disorders
JPS59148780A (ja) * 1983-02-07 1984-08-25 ブリストル―マイヤーズ スクイブ カンパニー 精神病治療性5−フルオロ−ピリミジン−2−イルピペラジン化合物
US4581357A (en) * 1983-02-07 1986-04-08 Mead Johnson & Company Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
CA1250291A (en) * 1984-07-23 1989-02-21 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)-piperazinyl derivatives of 1-pyrrolidin-2-ones
US4668687A (en) * 1984-07-23 1987-05-26 Bristol-Myers Company Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
US4612312A (en) * 1984-07-30 1986-09-16 Merrell Dow Pharmaceuticals Inc. Glutarimide antianxiety and antihypertensive agents
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
US4656173A (en) * 1985-04-24 1987-04-07 Bristol-Myers Company Antipsychotic benzisothiazole S-oxide compound
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
HUT43600A (en) * 1985-06-22 1987-11-30 Sandoz Ag Process for production of new thiazole derivatives and medical compound containing those
US4826843A (en) * 1985-07-08 1989-05-02 Bristol-Myers Cerebral function enhancing diazinylpiperidine derivatives
NZ216720A (en) * 1985-07-08 1990-09-26 Bristol Myers Co Diazinylpiperidine derivatives and pharmaceutical compositions
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
US4634703A (en) * 1985-10-25 1987-01-06 Bristol-Myers Company Method for alleviation of panic disorders
US4640921A (en) * 1986-02-04 1987-02-03 Bristol-Myers Treatment of sexual dysfunction with buspirone
PH25227A (en) * 1986-03-05 1991-03-27 Merrell Dow France Et Co Aromatic w-alkylamino-tetrahydro-6h-1,3-thiazin-6-one derivatives, pharmaceutical composition containing same and method of use thereof
AR242678A1 (es) * 1986-03-05 1993-04-30 Gonzalez Jorge Alberto Mejoras en instrumentos musicales de cuerda de arco.
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
US4687772A (en) * 1986-10-07 1987-08-18 Bristol-Myers Company Method for improvement of short term memory
CH677924A5 (xx) * 1987-02-25 1991-07-15 Egyt Gyogyszervegyeszeti Gyar
US4777173A (en) * 1987-03-25 1988-10-11 Bristol-Myers Company Method for treatment of alcohol abuse
US4797488A (en) * 1987-04-03 1989-01-10 American Home Products Corporation Psychotropic polycyclic imides
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4732983A (en) * 1987-04-03 1988-03-22 American Home Products Corporation Pyschotropic polycyclic imides
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
US5015646A (en) * 1987-08-28 1991-05-14 Bristol-Myers Squibb Co. Pharmaceutically useful polymorphic modification of buspirone
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
SE8704097D0 (sv) * 1987-10-22 1987-10-22 Astra Ab Oral formulation of buspirone and salts thereof
MX173180B (es) * 1987-10-26 1994-02-07 Pfizer Procedimiento para preparar agentes ansioliticos
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
US5242911A (en) * 1988-06-17 1993-09-07 Pfizer Inc. Bridged bicyclic imides as anxiolytics and antidepressants
US4859671A (en) * 1988-07-08 1989-08-22 American Home Products Corporation 2-substituted 1,2-benzisothiazol-3(2H)-one 1,1-dioxide useful as an anxiolytic agent
US5468749A (en) * 1988-08-30 1995-11-21 Gawin; Frank H. Method for treatment of substance addiction
WO1990002552A1 (en) * 1988-09-16 1990-03-22 Pfizer Inc. Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
WO1990006303A1 (en) * 1988-12-02 1990-06-14 Pfizer Inc. Arylpiperidine derivatives
US4873331A (en) * 1988-12-09 1989-10-10 American Home Products Corporation Noradamantyl-carboxylic acid piperazinoalkyl esters
US4882432A (en) * 1989-01-09 1989-11-21 American Home Products Corporation Polycyclic-carbamic acid piperazinoalkyl esters and amides
GB8909209D0 (en) * 1989-04-22 1989-06-07 Wyeth John & Brother Ltd Piperazine derivatives
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
HU212301B (en) * 1989-04-28 1996-05-28 Alkaloida Vegyeszeti Gyar Process for producing buspirone
US5703088A (en) * 1989-08-21 1997-12-30 Beth Israel Deaconess Medical Center, Inc. Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
FR2654934B1 (fr) * 1989-11-29 1994-09-30 Midy Spa Utilisation de derive [4-(2-pyrimidinyl)-1-piperazinyl] butyliques pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale.
US6432956B1 (en) 1990-02-12 2002-08-13 William C. Dement Method for treatment of sleep apneas
ES2019228A6 (es) * 1990-02-13 1991-06-01 Espanola Prod Quimicos Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5098904A (en) * 1990-06-27 1992-03-24 Bristol-Myers Squibb Company Cerebral function enhancing pyrimidinyl derivatives
ATE132866T1 (de) * 1990-10-23 1996-01-15 Akzo Nobel Nv 4-(4- oder 6-(trifluormethyl-2-pyridinyl)>-1- piperazinyl-alkyl substituierte laktame
SU1825501A3 (ru) * 1990-10-29 1995-12-10 И.В. Комиссаров Dl-3-[(4-[4- (2-пиридил)-1- пиперазинил]бутил)] -1,8,8-триметил -3-азабицикло[3,2,1] октан-2,4-диона дигидрохлорид, проявляющий противотревожную, нейролептическую и противорвотную активность
US5633009A (en) * 1990-11-28 1997-05-27 Sano Corporation Transdermal administration of azapirones
US5431922A (en) * 1991-03-05 1995-07-11 Bristol-Myers Squibb Company Method for administration of buspirone
US5591748A (en) * 1991-06-07 1997-01-07 Smithkline Beecham Corporation Immunomodulatory azaspiranes
US5137894A (en) * 1991-12-05 1992-08-11 New James S 4-(4-Piperidinyl-thieno[3,2-c]pyridine derivatives of n-alkylglutarimides
US5693645A (en) * 1992-12-23 1997-12-02 Beth Israel Deaconess Medical Center, Inc. Use of spiperone or spiperone derivatives as immunosuppressant agents
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
ES2201074T3 (es) * 1993-03-26 2004-03-16 Beth Israel Hospital Association Utilizacion topica o sistemica de buspirona o de derivados de esta para el tratamiento de trastornos patologicos asociados con reacciones inmunitarias.
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5338738A (en) * 1993-04-19 1994-08-16 Bristol-Myers Squibb Company Cerebral function enhancers: acyclic amide derivatives of pyrimidinylpiperidines
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
US5391570A (en) * 1993-10-14 1995-02-21 Bristol-Myers Squibb Aminomethyl-benzodioxane and benzopyran serotonergic agents
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법
US5538985A (en) * 1994-01-27 1996-07-23 Mitsui Toatsu Chemicals, Inc. Pyrrolidinone derivatives
CA2146593A1 (en) * 1994-05-05 1995-11-06 Jack Melton Large-scale process for azapirone synthesis
US5521313A (en) * 1994-05-05 1996-05-28 Bristol-Myers Squibb Company Process for preparing certain azapirones
ES2082727B1 (es) * 1994-09-01 1996-10-16 Univ Madrid Complutense Nuevos derivados de arilpiperazinas.
AU3079295A (en) * 1994-09-01 1996-03-22 Universidad Complutense De Madrid New arylpiperazine derivatives
ES2095811B1 (es) * 1995-07-28 1997-08-01 Univ Madrid Complutense Nuevos derivados de arilpiperazinas.
US5602128A (en) * 1994-12-02 1997-02-11 American Home Products Corporation N-heterocycloalkyl carboxamides as serotonergic agents
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
AU5101798A (en) * 1996-12-04 1998-06-29 Bristol-Myers Squibb Company Method for oral administration of buspirone
US5922341A (en) * 1997-10-28 1999-07-13 Vivus, Incorporated Local administration of pharmacologically active agents to treat premature ejaculation
US6228864B1 (en) 1997-10-28 2001-05-08 Vivus, Inc. Administration of 5-HT receptor agonists and antagonists, to treat premature ejaculation
US6037360A (en) * 1997-10-28 2000-03-14 Vivus, Incorporated Administration of 5-HT3 receptor antagonists to treat premature ejaculation
US6376494B1 (en) * 1998-06-15 2002-04-23 American Home Products Corporation Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents
US6312717B1 (en) 1998-07-07 2001-11-06 Bristol-Myers Squibb Company Method for treatment of anxiety and depression
WO2000006163A1 (en) * 1998-07-30 2000-02-10 Bristol-Myers Squibb Company Improved method for treatment of sleep-related respiratory disorders
US6313114B1 (en) 1999-01-07 2001-11-06 American Home Products Corp 3,4-Dihydro-2H-benzo[1,4]oxazinyl-methyl)-[3-(1H-indol-3yl)-alkyl]- amines
US6306859B1 (en) 1999-03-02 2001-10-23 American Home Products Corporation N-substituted imide derivatives with serotonergic activity
US6566361B2 (en) 1999-06-30 2003-05-20 Laboratories, Upsa Azapirone pain treatment
US6150365A (en) * 1999-08-05 2000-11-21 Bristol-Myers Squibb Company Anxiety method
US20030069251A1 (en) * 1999-08-05 2003-04-10 Yevich Joseph P. Antianxiety composition
US20050137206A1 (en) * 1999-08-05 2005-06-23 Yevich Joseph P. Method for treatment of anxiety and depression
US6831084B1 (en) 1999-11-12 2004-12-14 Wyeth Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-HT1A activity
BR0015539A (pt) 1999-11-12 2002-07-16 Wyeth Corp Adamantil e noradamantil aril- e aralquilpiperazinas ramificadas com atividade 5-ht1a de serotonina
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1341777B1 (en) * 2000-11-29 2007-09-26 Eli Lilly And Company 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatement of incontinence
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US7067518B2 (en) * 2002-09-05 2006-06-27 Wyeth Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
US20080217501A1 (en) * 2007-02-14 2008-09-11 Chad Jensen Power a-frame
CL2008000467A1 (es) * 2007-02-14 2008-08-22 Janssen Pharmaceutica Nv Compuestos derivados de 2-aminopirimidina, moduladores del receptor histamina h4; su procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno inflamatorio seleccionado de alegia, asma
US20090023744A1 (en) * 2007-06-18 2009-01-22 The General Hospital Corporation Combination therapy for depression
NZ583509A (en) 2007-09-14 2012-01-12 Janssen Pharmaceutica Nv Thieno-and furo-pyrimidine modulators of the histamine h4 receptor
MY158927A (en) 2008-06-12 2016-11-30 Janssen Pharmaceutica Nv Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h4 receptor
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
HUE031661T2 (en) 2010-10-15 2017-07-28 Contera Pharma Aps Combinations of serotonin receptor agonists for the treatment of movement disorders
US10561618B2 (en) 2012-04-18 2020-02-18 Contera Pharma Aps Orally available pharmaceutical formulation suitable for improved management of movement disorders
CN109689036A (zh) 2016-07-11 2019-04-26 康特拉医药公司 用于治疗早晨运动不能的脉冲药物输送系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL143925C (xx) * 1965-03-09
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation

Also Published As

Publication number Publication date
CH552608A (de) 1974-08-15
KE2691A (en) 1977-03-04
US3907801A (en) 1975-09-23
MY7700151A (en) 1977-12-31
CY886A (en) 1977-03-18
BE759371A (fr) 1971-05-24
US3717634A (en) 1973-02-20
DE2057845A1 (de) 1971-06-09
DK141753B (da) 1980-06-09
ES8505251A3 (es) 1985-05-16
DK141753C (xx) 1980-11-24
ES530335A0 (es) 1985-05-16
ZA707826B (en) 1971-07-28
FR2073406B1 (xx) 1974-10-11
FR2073406A1 (xx) 1971-10-01
GB1332194A (en) 1973-10-03
CH552607A (de) 1974-08-15
NL7017031A (xx) 1971-05-26

Similar Documents

Publication Publication Date Title
HK6177A (en) Heterocyclic azaspiroalkanediones
HK61677A (en) Triazolobenzodiazepine derivatives
KE2582A (en) Alkanolaminie derivatives
HK52076A (en) Nitrofuryl-pyrazolopyrimidinones
YU50370A (en) Rezrezovalnik koruze z vsaj dvema grabilnima valjema
IL34685A (en) Dibenzodioxocine derivatives
ZA707762B (en) Heterocyclic compounds
CY806A (en) Phenylaminoethanol derivatives
PH9290A (en) Tetrahydrocyclopropadibenzazepine derivatives
CS13780A2 (en) Zpusob deformovani protahleho clenu
CY819A (en) Indenopyridine derivatives
HU171745B (hu) Duplicating machine
ZA704094B (en) 2-hydroxy-5-benzamide derivatives
ZA705176B (en) Hydroxyisoquinuclidine derivatives
ZA704013B (en) Benzoisothiazol derivatives
YU21470A (en) Skladovni ploscati kontener z gibljivo opremo
CS153066B2 (en) Zpusob vyroby fenoxyprobanolaminuz
IL33814A0 (en) Substituted bis-benzimidazoles
ZA704654B (en) Heterocyclic compounds
CA31965S (en) Raincape
CA31286S (en) Brooh
EG10937A (en) Automatenpicker
CA31961S (en) Surcoat
CA31495S (en) Scent-bottle
CA31694S (en) Handril