ES2019228A6 - Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona. - Google Patents

Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.

Info

Publication number
ES2019228A6
ES2019228A6 ES9000421A ES9000421A ES2019228A6 ES 2019228 A6 ES2019228 A6 ES 2019228A6 ES 9000421 A ES9000421 A ES 9000421A ES 9000421 A ES9000421 A ES 9000421A ES 2019228 A6 ES2019228 A6 ES 2019228A6
Authority
ES
Spain
Prior art keywords
azaspyro
decane
radical
new
dione derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9000421A
Other languages
English (en)
Inventor
Venero Aurelio Orjales
Solanes Rosa Rodes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Original Assignee
Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA filed Critical Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Priority to ES9000421A priority Critical patent/ES2019228A6/es
Priority to PT96739A priority patent/PT96739A/pt
Priority to EP19910500014 priority patent/EP0447345A3/en
Priority to FI910652A priority patent/FI910652A/fi
Priority to AU70983/91A priority patent/AU7098391A/en
Priority to NO91910564A priority patent/NO910564L/no
Priority to JP3041144A priority patent/JPH0892221A/ja
Priority to CA002036269A priority patent/CA2036269A1/en
Priority to KR1019910002512A priority patent/KR910015564A/ko
Publication of ES2019228A6 publication Critical patent/ES2019228A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE NEVOS DERIVADOS DE AZASPIRO W4.5W DECANO-7,9-DIONA DE FORMULA GENERAL (I), FORMULA QUE SE CARACTERIZA PORQUE SE HACEN REACCIONAR EN EL SENO DE UN DISOLVENTE APROPIADO, PREFERENTEMENTE PIRIDINA TOLUENO Y BUTANOL, Y A UNA TEMPERATURA ADECUADA COMPRENDIDA ENTRE 80 Y 140GC, PREFERENTEMENTE A LA TEMPERATURA DE EBULLICION DEL DISOLVENTE EMPLEADO, EL ANHIDRIDO 3,3-TETRAMETILENGLUTARICO CON UNA AMINA PRIMARIA DE FORMULA GENERAL (II): FORMULA.
ES9000421A 1990-02-13 1990-02-13 Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona. Expired - Lifetime ES2019228A6 (es)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES9000421A ES2019228A6 (es) 1990-02-13 1990-02-13 Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.
PT96739A PT96739A (pt) 1990-02-13 1991-02-11 Processo de obtencao de novos derivados de azaspiro{4,5}decano-7,9-diona
EP19910500014 EP0447345A3 (en) 1990-02-13 1991-02-11 New azaspyro (4.5) decane-7,9-dione derivatives
FI910652A FI910652A (fi) 1990-02-13 1991-02-11 Foerfarande foer framstaellning av nya azaspiro(4,5)dekan-7,9-dionderivat.
AU70983/91A AU7098391A (en) 1990-02-13 1991-02-12 New azaspyro(4.5)decane-7,9-dione derivatives
NO91910564A NO910564L (no) 1990-02-13 1991-02-12 Fremgangsmaate for fremstilling av azaspiro(4,5)decan-7,9-dionderivater.
JP3041144A JPH0892221A (ja) 1990-02-13 1991-02-13 新規アザスピロ［４，５］デカン−７，９−ジオン 誘導体
CA002036269A CA2036269A1 (en) 1990-02-13 1991-02-13 Azaspyro¬4.5|decane-7,9-dione derivatives and process for preparing same
KR1019910002512A KR910015564A (ko) 1990-02-13 1991-02-13 아자스피로[4,5] 데칸-7,9-디온 유도체

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9000421A ES2019228A6 (es) 1990-02-13 1990-02-13 Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.

Publications (1)

Publication Number Publication Date
ES2019228A6 true ES2019228A6 (es) 1991-06-01

Family

ID=8265901

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9000421A Expired - Lifetime ES2019228A6 (es) 1990-02-13 1990-02-13 Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.

Country Status (9)

Country Link
EP (1) EP0447345A3 (es)
JP (1) JPH0892221A (es)
KR (1) KR910015564A (es)
AU (1) AU7098391A (es)
CA (1) CA2036269A1 (es)
ES (1) ES2019228A6 (es)
FI (1) FI910652A (es)
NO (1) NO910564L (es)
PT (1) PT96739A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2338037A1 (en) 1998-07-17 2000-01-27 Synaptic Pharmaceutical Corporation Compounds specific for the human .alpha.1d adrenergic receptor and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides

Also Published As

Publication number Publication date
NO910564D0 (no) 1991-02-12
EP0447345A2 (en) 1991-09-18
FI910652A0 (fi) 1991-02-11
AU7098391A (en) 1991-08-15
NO910564L (no) 1991-08-14
PT96739A (pt) 1991-10-31
FI910652A (fi) 1991-08-14
KR910015564A (ko) 1991-09-30
CA2036269A1 (en) 1991-08-14
EP0447345A3 (en) 1992-04-15
JPH0892221A (ja) 1996-04-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041004