HK50485A - Carbostyrile derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Carbostyrile derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
HK50485A
HK50485A HK504/85A HK50485A HK50485A HK 50485 A HK50485 A HK 50485A HK 504/85 A HK504/85 A HK 504/85A HK 50485 A HK50485 A HK 50485A HK 50485 A HK50485 A HK 50485A
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
carbostyrile
derivatives
Prior art date
Application number
HK504/85A
Other languages
English (en)
Inventor
Erich Dr Dipl-Chem Mueller
Josef Dr Dipl-Chem Nickl
Josef Dr Dipl-Chem Roch
Berthold Dr Dipl-Chem Narr
Walter Dr Haarmann
Johannes Maximili Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782806721 external-priority patent/DE2806721A1/de
Priority claimed from DE19782853314 external-priority patent/DE2853314A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of HK50485A publication Critical patent/HK50485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Indole Compounds (AREA)
HK504/85A 1978-02-17 1985-07-04 Carbostyrile derivatives,their preparation and pharmaceutical compositions containing them HK50485A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782806721 DE2806721A1 (de) 1978-02-17 1978-02-17 Neue carbostyril-derivate
DE19782853314 DE2853314A1 (de) 1978-12-09 1978-12-09 Neue carbostyril- und oxindolderivate, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
HK50485A true HK50485A (en) 1985-07-12

Family

ID=25773852

Family Applications (1)

Application Number Title Priority Date Filing Date
HK504/85A HK50485A (en) 1978-02-17 1985-07-04 Carbostyrile derivatives,their preparation and pharmaceutical compositions containing them

Country Status (24)

Country Link
EP (1) EP0003771B1 (ro)
JP (1) JPS54132581A (ro)
AT (1) AT374183B (ro)
AU (1) AU523147B2 (ro)
CA (1) CA1116600A (ro)
CS (1) CS227005B2 (ro)
DD (1) DD141829A5 (ro)
DE (1) DE2963868D1 (ro)
DK (1) DK157017C (ro)
ES (3) ES477517A1 (ro)
FI (1) FI69064C (ro)
GR (1) GR66565B (ro)
HK (1) HK50485A (ro)
HU (1) HU177522B (ro)
IE (1) IE48179B1 (ro)
IL (1) IL56677A (ro)
NO (1) NO152839C (ro)
NZ (1) NZ189685A (ro)
PH (1) PH16698A (ro)
PL (3) PL119177B1 (ro)
PT (1) PT69244A (ro)
RO (2) RO76683A (ro)
SU (2) SU843739A3 (ro)
YU (1) YU41146B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1171624B (it) * 1980-11-12 1987-06-10 Thomae Gmbh Dr K Indolinoni dotati di proprieta' farmaceutiche e procedimento per la loro produzione
US4442111A (en) * 1981-07-25 1984-04-10 Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung Antithrombotic sulfimino and sulfoximino indolinones-2
DE3217012A1 (de) * 1982-05-06 1983-11-10 Dr. Karl Thomae Gmbh, 7950 Biberach Benzoxazin-2-one, deren herstellung und diese verbindungen enthaltende arzneimittel
AU653060B2 (en) * 1991-08-23 1994-09-15 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelet agglutination inhibitor
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
MY129350A (en) 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5082218A (ro) * 1973-11-10 1975-07-03
US3904761A (en) * 1974-01-25 1975-09-09 Hoechst Co American Method of preventing thrombosis
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use
JPS5321176A (en) * 1976-08-09 1978-02-27 Otsuka Pharmaceut Co Ltd Carbostyryl derivatives
NZ187452A (en) * 1977-06-10 1980-05-27 Otsuka Pharma Co Ltd N- substituted-aminocarbonylpropoxy-carbostyrils and their preparation

Also Published As

Publication number Publication date
ATA93379A (de) 1983-08-15
SU843739A3 (ru) 1981-06-30
DE2963868D1 (en) 1982-11-25
DK157017B (da) 1989-10-30
ES484634A1 (es) 1980-05-16
FI790507A (fi) 1979-08-18
JPS54132581A (en) 1979-10-15
YU36679A (en) 1983-02-28
PL119177B1 (en) 1981-12-31
NO152839B (no) 1985-08-19
YU41146B (en) 1986-12-31
PH16698A (en) 1984-01-16
ES484633A1 (es) 1980-05-16
EP0003771B1 (de) 1982-10-20
AU523147B2 (en) 1982-07-15
GR66565B (ro) 1981-03-27
AT374183B (de) 1984-03-26
PL119423B1 (en) 1981-12-31
IL56677A (en) 1982-09-30
SU852170A3 (ru) 1981-07-30
IE790313L (en) 1979-08-17
DK69679A (da) 1979-08-18
JPS6331464B2 (ro) 1988-06-23
NZ189685A (en) 1984-07-06
FI69064C (fi) 1985-12-10
EP0003771A1 (de) 1979-09-05
RO82013B (ro) 1983-05-30
AU4432979A (en) 1979-08-23
CA1116600A (en) 1982-01-19
DK157017C (da) 1990-03-26
IE48179B1 (en) 1984-10-17
PL213471A1 (ro) 1980-02-25
NO152839C (no) 1985-11-27
NO790521L (no) 1979-08-20
FI69064B (fi) 1985-08-30
RO76683A (ro) 1981-05-30
RO82013A (ro) 1983-06-01
CS227005B2 (en) 1984-04-16
PL117771B1 (en) 1981-08-31
DD141829A5 (de) 1980-05-21
ES477517A1 (es) 1980-01-16
IL56677A0 (en) 1979-05-31
HU177522B (en) 1981-10-28
PT69244A (de) 1979-03-01

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