HK21795A - Cross-protective human monoclonal antibody compositions - Google Patents

Cross-protective human monoclonal antibody compositions

Info

Publication number
HK21795A
HK21795A HK21795A HK21795A HK21795A HK 21795 A HK21795 A HK 21795A HK 21795 A HK21795 A HK 21795A HK 21795 A HK21795 A HK 21795A HK 21795 A HK21795 A HK 21795A
Authority
HK
Hong Kong
Prior art keywords
crl
human monoclonal
antibodies
cross
monoclonal antibody
Prior art date
Application number
HK21795A
Other languages
English (en)
Inventor
V Raff Howard
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of HK21795A publication Critical patent/HK21795A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK21795A 1986-02-07 1995-02-16 Cross-protective human monoclonal antibody compositions HK21795A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82800586A 1986-02-07 1986-02-07
US94449586A 1986-12-19 1986-12-19

Publications (1)

Publication Number Publication Date
HK21795A true HK21795A (en) 1995-02-24

Family

ID=27125154

Family Applications (1)

Application Number Title Priority Date Filing Date
HK21795A HK21795A (en) 1986-02-07 1995-02-16 Cross-protective human monoclonal antibody compositions

Country Status (28)

Country Link
US (2) US5717071A (show.php)
JP (1) JP2645343B2 (show.php)
KR (1) KR870007697A (show.php)
CN (1) CN87102167A (show.php)
AT (1) AT398781B (show.php)
BE (1) BE1000967A5 (show.php)
CA (1) CA1339013C (show.php)
CH (1) CH672072A5 (show.php)
DE (1) DE3703711A1 (show.php)
DK (1) DK63187A (show.php)
ES (1) ES2009140A6 (show.php)
FI (1) FI94489C (show.php)
FR (1) FR2595946B1 (show.php)
GB (1) GB2186592B (show.php)
GR (1) GR870194B (show.php)
HK (1) HK21795A (show.php)
HU (1) HU203583B (show.php)
IE (1) IE59627B1 (show.php)
IL (1) IL81370A (show.php)
IT (1) IT1207589B (show.php)
LU (1) LU86761A1 (show.php)
MX (1) MX9203629A (show.php)
NL (1) NL8700286A (show.php)
NO (1) NO176924C (show.php)
NZ (2) NZ233920A (show.php)
OA (1) OA08477A (show.php)
PT (1) PT84258B (show.php)
SE (1) SE468747B (show.php)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256713A3 (en) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutic human antipseudomonas aeruginosa antibodies
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
DE3925161A1 (de) * 1989-03-15 1990-09-27 Boehringer Mannheim Gmbh Monoklonale, gegen eca gerichtete antikoerper und ihre verwendung
WO1990013660A2 (en) * 1989-05-09 1990-11-15 Cetus Corporation Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria
US6315999B1 (en) 1989-08-10 2001-11-13 Solvay, S.A. Pharmaceutical product for the treatment of sepsis
GB8918232D0 (en) * 1989-08-10 1989-09-20 Opal Stephen M Pharmaceutical product for the treatment of septic shock
US20080139789A1 (en) * 1990-10-22 2008-06-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated Broadly Reactive Opsonic Immunoglobulin for Treating a Pathogenic Coagulase-Negative Staphylococcus Infection
WO1993019373A1 (en) * 1992-03-19 1993-09-30 U.S. GOVERNMENT, as represented by THE SECRETARY O Broadly reactive opsonic antibodies that react with common staphylococcal antigens
EP0680337A4 (en) * 1993-01-12 1997-07-30 Anthony George Gristina METHODS AND COMPOSITIONS FOR DIRECT APPLICATION WITH HIGH CONCENTRATION OF ANTIBODIES, PRODUCING PASSIVE IMMUNITY.
US5510264A (en) * 1993-09-28 1996-04-23 Insight Biotech Inc. Antibodies which bind meningitis related homologous antigenic sequences
WO1999054357A1 (en) * 1998-04-14 1999-10-28 Chugai Research Institute For Molecular Medicine, Inc. Novel cytokine-like protein
KR101595234B1 (ko) * 2007-07-23 2016-02-26 사노피 파스퇴르 리미티드 면역원성 폴리펩타이드 및 단일클론 항체
SG174367A1 (en) * 2009-03-23 2011-10-28 Quark Pharmaceuticals Inc Compounds compositions and methods of treating cancer and fibrotic diseases
RU2589256C2 (ru) 2010-12-03 2016-07-10 Санофи Пастер Лимитид Композиции и способы для иммунизации против streptococcus pneumoniae
AU2016353073A1 (en) * 2015-11-10 2018-06-07 Visterra, Inc. Antibody molecule-drug conjugates that specifically binds to lipopolysaccharide and uses thereof
CA3049449A1 (en) 2017-01-18 2018-07-26 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
AU2021248643A1 (en) 2020-04-03 2022-10-27 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
AU567693B2 (en) * 1982-09-30 1987-12-03 University Of Rochester Human monoclonal antibodies against bacterial toxins
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
US4675287A (en) * 1984-07-26 1987-06-23 Scripps Clinic And Research Foundation Monoclonal antibody directed to human ganglioside GD2
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus

Also Published As

Publication number Publication date
HU203583B (en) 1991-08-28
SE8700467L (sv) 1987-08-08
CA1339013C (en) 1997-03-25
SE468747B (sv) 1993-03-15
KR870007697A (ko) 1987-09-21
IL81370A (en) 1991-06-30
GB8702689D0 (en) 1987-03-11
FI94489C (fi) 1995-09-25
AT398781B (de) 1995-01-25
FI870502A0 (fi) 1987-02-06
GR870194B (en) 1987-06-10
HUT46062A (en) 1988-09-28
US5717071A (en) 1998-02-10
CN87102167A (zh) 1988-02-03
BE1000967A5 (fr) 1989-05-30
DK63187D0 (da) 1987-02-06
NO870476L (no) 1987-08-10
CH672072A5 (show.php) 1989-10-31
IT1207589B (it) 1989-05-25
ES2009140A6 (es) 1989-09-01
IE870320L (en) 1987-08-07
IT8719292A0 (it) 1987-02-06
NO176924C (no) 1995-06-21
FR2595946A1 (fr) 1987-09-25
LU86761A1 (fr) 1987-09-15
NZ219187A (en) 1990-12-21
MX9203629A (es) 1992-07-01
ATA26287A (de) 1994-06-15
SE8700467D0 (sv) 1987-02-06
GB2186592B (en) 1990-08-01
NO870476D0 (no) 1987-02-06
GB2186592A (en) 1987-08-19
DE3703711C2 (show.php) 1993-06-24
PT84258A (en) 1987-03-01
JP2645343B2 (ja) 1997-08-25
IE59627B1 (en) 1994-03-09
FI870502L (fi) 1987-08-08
FI94489B (fi) 1995-06-15
NO176924B (no) 1995-03-13
JPS62270535A (ja) 1987-11-24
PT84258B (pt) 1989-09-14
DK63187A (da) 1987-08-08
NZ233920A (en) 1990-12-21
FR2595946B1 (fr) 1991-10-04
NL8700286A (nl) 1987-09-01
IL81370A0 (en) 1987-08-31
US5837541A (en) 1998-11-17
OA08477A (fr) 1988-07-29
DE3703711A1 (de) 1987-09-24

Similar Documents

Publication Publication Date Title
HK21795A (en) Cross-protective human monoclonal antibody compositions
SE8605295D0 (sv) Monoclonal antibodies cross-reactive and crossprotective against p. aeruginosa serotypes
UA29494C2 (uk) Гуманізовані антитіла, способи їх продукування, спосіб лікування хвороби крона, спосіб лікування розсіяного склерозу, фармацевтична композиція
DE69531679D1 (de) Für e-selectin und p-selectin spezifische kreuzreaktive monoklonale antikörper
PT730608E (pt) Composicoes compreendendo hidratos de carbono e proeinas relacionadas pelo complemento e metodos para produzir e utilizar as referidas composicoes
ATE163195T1 (de) Lösliche liganden für cd40
EP0528931A4 (en) Humanized chimeric anti-icam-1 antibodies, methods of preparation and use
HUP0102535A2 (hu) Új CD 19xCD3 specifikus polipeptidek és alkalmazásuk
CA2128511A1 (en) Monomeric and dimeric antibody-fragment fusion proteins
AU7079396A (en) Anti-galalpha(1,3)gal antibody binding peptides
PT1053256E (pt) Anticorpos para o receptor de morte 4 (dr4) e utilizações destes
IT8821134A0 (it) Frazioni oligomeriche procianidoliche, loro procedimentodi preparazione e composizioni farmaceutiche che le contengono.
CA2093667A1 (en) Mouse monoclonal antibodies and uses thereof
AU2002223462A1 (en) Use of cd28-specific monoclonal antibodies for stimulating blood cells that lackcd28
DE69727142D1 (de) Verwendung eines bpi proteinproduktes als antithrombotisches mittel
ES2132556T3 (es) Nuevo derivado de benzo-tiadiazina, su procedimiento de preparacion y las composiciones farmaceuticas que lo contienen.
ES2013321A6 (es) Un metodo de produccion de anticuerpos monoclonales
GEP20002257B (en) Method for Reducing Fibrin Accumulation Speed, Prophylactics of Thrombus Complications and Treatment of Blood Vessels Diseases, Medicinal Composition and Medicinal Species
EP1211311A3 (en) Cord blood-derived activated lymphocytes and preparations containing said lymphocytes
IE861494L (en) Protective human monoclonal antibodies to pseudomonas¹aeruginosa exotoxin a
AU584690B2 (en) E87ag antigen of pseudomonas aeruginosa, monoclonal antibody against it, and hybridoma
AU6176596A (en) Compositions exhibiting adp-ribosyltransferase activity and methods for the preparation and use thereof
NO941347L (no) Fremgangsmåte for fremstilling av et humant monoklonalt antistoff
FI971879L (fi) Allogeenisten ja ksenogeenisten proteiinien vasta-aineet, niiden käyttö diagnoosissa ja hoidossa ja menetelmät niiden määrittämiseksi
WO1990013660A3 (en) Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)