WO1990013660A3 - Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria - Google Patents

Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria Download PDF

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Publication number
WO1990013660A3
WO1990013660A3 PCT/US1990/002558 US9002558W WO9013660A3 WO 1990013660 A3 WO1990013660 A3 WO 1990013660A3 US 9002558 W US9002558 W US 9002558W WO 9013660 A3 WO9013660 A3 WO 9013660A3
Authority
WO
WIPO (PCT)
Prior art keywords
monoclonal antibodies
human monoclonal
sero
gram
negative bacteria
Prior art date
Application number
PCT/US1990/002558
Other languages
French (fr)
Other versions
WO1990013660A2 (en
Inventor
Alois B Lang
James W Larrick
Stanley J Cryz
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of WO1990013660A2 publication Critical patent/WO1990013660A2/en
Publication of WO1990013660A3 publication Critical patent/WO1990013660A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Static Random-Access Memory (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Prophylactic or therapeutic compositions are described that are useful for treating bacteremic infections consisting of human monoclonal antibodies that bind to Pseudomonas aeruginosa, Klebsiella, and E. coli alone or in combination. Also described are methods for using the composition to treat patients suffering from bacteremic infections.
PCT/US1990/002558 1989-05-09 1990-05-08 Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria WO1990013660A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34959489A 1989-05-09 1989-05-09
US349,594 1989-05-09

Publications (2)

Publication Number Publication Date
WO1990013660A2 WO1990013660A2 (en) 1990-11-15
WO1990013660A3 true WO1990013660A3 (en) 1990-12-13

Family

ID=23373107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1990/002558 WO1990013660A2 (en) 1989-05-09 1990-05-08 Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria

Country Status (3)

Country Link
JP (1) JPH0329196A (en)
AU (1) AU5675790A (en)
WO (1) WO1990013660A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370872A (en) * 1991-08-12 1994-12-06 Swiss Serum And Vaccine Institute Berne Escherichia coliO-polysaccharide-protein conjugate vaccine
US6294171B2 (en) * 1999-09-14 2001-09-25 Milkhaus Laboratory, Inc. Methods for treating disease states comprising administration of low levels of antibodies
EP2098536A1 (en) 2008-03-05 2009-09-09 4-Antibody AG Isolation and identification of antigen- or ligand-specific binding proteins

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001807A1 (en) * 1984-09-07 1986-03-27 Technology Licence Company Limited Monoclonal antibodies and their use
GB2185266A (en) * 1985-12-10 1987-07-15 Genetic Systems Corp Monoclonal antibodies cross-reactive and cross-protective against P. aeruginosa serotypes
GB2186592A (en) * 1986-02-07 1987-08-19 Genetic Systems Corp Cross-protective human monoclonal antibody compositions
EP0338395A2 (en) * 1988-04-19 1989-10-25 BEHRINGWERKE Aktiengesellschaft Monoclonal antibodies to Pseudomonas aeruginosa, their production and use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001807A1 (en) * 1984-09-07 1986-03-27 Technology Licence Company Limited Monoclonal antibodies and their use
GB2185266A (en) * 1985-12-10 1987-07-15 Genetic Systems Corp Monoclonal antibodies cross-reactive and cross-protective against P. aeruginosa serotypes
GB2186592A (en) * 1986-02-07 1987-08-19 Genetic Systems Corp Cross-protective human monoclonal antibody compositions
EP0338395A2 (en) * 1988-04-19 1989-10-25 BEHRINGWERKE Aktiengesellschaft Monoclonal antibodies to Pseudomonas aeruginosa, their production and use

Also Published As

Publication number Publication date
AU5675790A (en) 1990-11-29
JPH0329196A (en) 1991-02-07
WO1990013660A2 (en) 1990-11-15

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