HK1258148A1 - 核酸探針和檢測基因組片段的方法 - Google Patents

核酸探針和檢測基因組片段的方法

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Publication number
HK1258148A1
HK1258148A1 HK19100502.0A HK19100502A HK1258148A1 HK 1258148 A1 HK1258148 A1 HK 1258148A1 HK 19100502 A HK19100502 A HK 19100502A HK 1258148 A1 HK1258148 A1 HK 1258148A1
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HK
Hong Kong
Prior art keywords
nucleic acid
acid probe
genomic fragments
detecting genomic
detecting
Prior art date
Application number
HK19100502.0A
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English (en)
Inventor
C‧O‧F‧達爾
J‧O‧埃瑞克森
Original Assignee
蘇州新波生物技術有限公司
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Publication of HK1258148A1 publication Critical patent/HK1258148A1/zh

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/501—Ligase
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/161—Modifications characterised by incorporating target specific and non-target specific sites
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30—Oligonucleotides characterised by their secondary structure
    • C12Q2525/301—Hairpin oligonucleotides
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30—Oligonucleotides characterised by their secondary structure
    • C12Q2525/307—Circular oligonucleotides
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/125—Rolling circle
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK19100502.0A 2013-12-02 2019-01-14 核酸探針和檢測基因組片段的方法 HK1258148A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1321191.7A GB2520763A (en) 2013-12-02 2013-12-02 Nucleic acid probe and method of detecting genomic fragments

Publications (1)

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HK1258148A1 true HK1258148A1 (zh) 2019-11-08

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US (3) US10240198B2 (zh)
EP (2) EP3077540B1 (zh)
JP (3) JP6542771B2 (zh)
KR (1) KR102390285B1 (zh)
CN (2) CN108707652B (zh)
AU (2) AU2014358861B2 (zh)
BR (1) BR112016012264B1 (zh)
CA (1) CA2931013C (zh)
ES (2) ES2818920T3 (zh)
GB (1) GB2520763A (zh)
HK (1) HK1258148A1 (zh)
RU (1) RU2733888C2 (zh)
WO (1) WO2015083001A2 (zh)

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GB2520763A (en) 2013-12-02 2015-06-03 Vanadis Diagnostics Ab Nucleic acid probe and method of detecting genomic fragments
US10174383B2 (en) 2014-08-13 2019-01-08 Vanadis Diagnostics Method of estimating the amount of a methylated locus in a sample
GB201507376D0 (en) 2015-04-30 2015-06-17 Vanadis Diagnostics Ab Use of a porous transparent capillary membrane for counting rolling circle amplification products
CN106536735B (zh) 2015-09-18 2020-01-14 苏州新波生物技术有限公司 分析dna样品的探针集合和使用所述探针集合的方法
JPWO2017135383A1 (ja) * 2016-02-03 2018-12-06 国立大学法人豊橋技術科学大学 偽環状二重鎖ポリヌクレオチドと、それを用いた遺伝子発現阻害剤
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CN110225979B (zh) * 2017-05-23 2024-05-31 深圳华大基因股份有限公司 基于滚环扩增的基因组目标区域富集方法及其应用
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CN117377775A (zh) * 2021-04-29 2024-01-09 因美纳有限公司 用于核酸表征的扩增技术
WO2023282164A1 (ja) * 2021-07-08 2023-01-12 国立大学法人九州大学 プローブ、プローブセット、及び哺乳動物の核酸検出キット
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KR20160096633A (ko) 2016-08-16
JP2019176867A (ja) 2019-10-17
BR112016012264A2 (pt) 2017-09-26
US10240198B2 (en) 2019-03-26
GB2520763A (en) 2015-06-03
US20190194748A1 (en) 2019-06-27
US20170016065A1 (en) 2017-01-19
AU2021200461A1 (en) 2021-02-25
AU2014358861A1 (en) 2016-06-09
BR112016012264B1 (pt) 2023-04-25
CN105899680B (zh) 2018-06-15
WO2015083001A3 (en) 2015-11-26
US10731214B2 (en) 2020-08-04
CA2931013A1 (en) 2015-06-11
KR102390285B1 (ko) 2022-04-25
JP2016537990A (ja) 2016-12-08
CN108707652A (zh) 2018-10-26
RU2733888C2 (ru) 2020-10-07
ES2818920T3 (es) 2021-04-14
JP6766236B2 (ja) 2020-10-07
EP3770273A1 (en) 2021-01-27
JP6571895B1 (ja) 2019-09-04
CA2931013C (en) 2023-06-06
EP3077540B1 (en) 2020-09-02
CN105899680A (zh) 2016-08-24
JP2019216734A (ja) 2019-12-26
WO2015083001A2 (en) 2015-06-11
GB201321191D0 (en) 2014-01-15
AU2021200461B2 (en) 2022-10-06
CN108707652B (zh) 2022-04-15
ES2899693T3 (es) 2022-03-14
EP3077540A2 (en) 2016-10-12
AU2014358861B2 (en) 2020-12-10
JP6542771B2 (ja) 2019-07-10
EP3770273B1 (en) 2021-09-29
US20200318186A1 (en) 2020-10-08

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