HK1252152A1 - 用於評估無細胞dna的多重優化錯配擴增(moma)實時pcr - Google Patents
用於評估無細胞dna的多重優化錯配擴增(moma)實時pcrInfo
- Publication number
- HK1252152A1 HK1252152A1 HK18111543.9A HK18111543A HK1252152A1 HK 1252152 A1 HK1252152 A1 HK 1252152A1 HK 18111543 A HK18111543 A HK 18111543A HK 1252152 A1 HK1252152 A1 HK 1252152A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- moma
- real time
- time pcr
- free dna
- assessing cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562155453P | 2015-04-30 | 2015-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1252152A1 true HK1252152A1 (zh) | 2019-05-17 |
Family
ID=56027193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18111543.9A HK1252152A1 (zh) | 2015-04-30 | 2018-09-07 | 用於評估無細胞dna的多重優化錯配擴增(moma)實時pcr |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180142296A1 (zh) |
| EP (1) | EP3289102A1 (zh) |
| JP (2) | JP2018514219A (zh) |
| CN (1) | CN107849604A (zh) |
| AU (2) | AU2016255573A1 (zh) |
| BR (1) | BR112017023232A2 (zh) |
| CA (1) | CA2984352A1 (zh) |
| EA (1) | EA201792389A1 (zh) |
| HK (1) | HK1252152A1 (zh) |
| IL (2) | IL255301B (zh) |
| MX (1) | MX2017013878A (zh) |
| WO (1) | WO2016176662A1 (zh) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US8825412B2 (en) | 2010-05-18 | 2014-09-02 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10385396B2 (en) | 2012-04-19 | 2019-08-20 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| JP6659575B2 (ja) | 2014-04-21 | 2020-03-04 | ナテラ， インコーポレイテッド | 変異の検出および染色体分節の倍数性 |
| WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| EP3449019B1 (en) | 2016-04-29 | 2023-08-23 | The Medical College of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-target number |
| EA201892491A1 (ru) * | 2016-04-29 | 2019-06-28 | Дзе Медикал Колледж Оф Висконсин, Инк. | Пцр в реальном времени с мультиплексной оптимизированной амплификацией неправильно спаренных оснований (moma) для анализа злокачественных новообразований |
| BR112018072197A2 (pt) * | 2016-04-29 | 2019-02-12 | Medical College Wisconsin Inc | amplificação de emparelhamento optimizado múltiplo (moma) - pcr de tempo real para avaliar o poço fetal |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| JP2019534016A (ja) * | 2016-11-02 | 2019-11-28 | ザ メディカル カレッジ オブ ウィスコンシン，インコーポレイテッドＴｈｅ Ｍｅｄｉｃａｌ Ｃｏｌｌｅｇｅ ｏｆ Ｗｉｓｃｏｎｓｉｎ， Ｉｎｃ． | 全および特異的な無細胞ｄｎａを使用しリスクを評価するための方法 |
| CA3042722A1 (en) * | 2016-11-02 | 2018-05-11 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using mismatch amplification and statistical methods |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| WO2018237078A1 (en) | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | ASSESSMENT OF CONDITIONS IN GRAFT SUBJECTS USING SPECIFIC ACELLULAR DNA FROM A DONOR |
| WO2018237075A1 (en) | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | ASSESSING THE RISK OF GRAFT COMPLICATION WITH TOTAL ACELLULAR DNA |
| CA3067635A1 (en) * | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| WO2019035995A1 (en) * | 2017-08-17 | 2019-02-21 | Tai Diagnostics, Inc. | METHODS OF DETERMINING FREE DNA FROM A DONOR WITHOUT DONOR GENOTYPE |
| US11479819B2 (en) | 2017-12-15 | 2022-10-25 | Acrannolife Genomics Pvt. Ltd. | Non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| US11525159B2 (en) | 2018-07-03 | 2022-12-13 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020131955A1 (en) * | 2018-12-17 | 2020-06-25 | The Medical College Of Wisconsin, Inc. | Assessing risk with total cell-free dna |
| WO2020206290A1 (en) * | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total cell-free dna |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| WO2021236962A1 (en) | 2020-05-20 | 2021-11-25 | The Medical College Of Wisconsin, Inc. | Compositions and methods for inhibiting cytokine-release syndrome |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60123448T2 (de) * | 2001-12-24 | 2007-08-23 | Prof. Wolfgang Holzgreve | Verfahren zur nicht-invasiven Diagnose von Transplantationen und Transfusionen |
| AU2010315084A1 (en) * | 2009-11-06 | 2012-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive diagnosis of graft rejection in organ transplant patients |
| US20130143219A1 (en) * | 2010-01-28 | 2013-06-06 | Medical College of Wisconsin Inc. | Methods and compositions for high yield, specific amplification |
| WO2011118603A1 (ja) * | 2010-03-24 | 2011-09-29 | 凸版印刷株式会社 | 競合プライマーによる標的塩基配列の検出方法 |
| US10385396B2 (en) * | 2012-04-19 | 2019-08-20 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| SG11201506660RA (en) * | 2013-02-21 | 2015-09-29 | Toma Biosciences Inc | Methods, compositions, and kits for nucleic acid analysis |
| WO2014194113A2 (en) * | 2013-05-29 | 2014-12-04 | Chronix Biomedical | Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients |
-
2016
- 2016-04-29 AU AU2016255573A patent/AU2016255573A1/en not_active Abandoned
- 2016-04-29 CA CA2984352A patent/CA2984352A1/en active Pending
- 2016-04-29 JP JP2017557142A patent/JP2018514219A/ja active Pending
- 2016-04-29 BR BR112017023232A patent/BR112017023232A2/pt not_active IP Right Cessation
- 2016-04-29 CN CN201680039018.XA patent/CN107849604A/zh active Pending
- 2016-04-29 EP EP16724189.2A patent/EP3289102A1/en active Pending
- 2016-04-29 US US15/570,560 patent/US20180142296A1/en active Pending
- 2016-04-29 EA EA201792389A patent/EA201792389A1/ru unknown
- 2016-04-29 WO PCT/US2016/030313 patent/WO2016176662A1/en active Application Filing
- 2016-04-29 MX MX2017013878A patent/MX2017013878A/es unknown
-
2017
- 2017-10-29 IL IL255301A patent/IL255301B/en unknown
-
2018
- 2018-09-07 HK HK18111543.9A patent/HK1252152A1/zh unknown
-
2021
- 2021-08-03 JP JP2021127555A patent/JP2022002508A/ja active Pending
- 2021-12-26 IL IL289404A patent/IL289404A/en unknown
-
2022
- 2022-05-23 AU AU2022203482A patent/AU2022203482A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL255301B (en) | 2022-02-01 |
| JP2018514219A (ja) | 2018-06-07 |
| JP2022002508A (ja) | 2022-01-11 |
| CA2984352A1 (en) | 2016-11-03 |
| EP3289102A1 (en) | 2018-03-07 |
| WO2016176662A1 (en) | 2016-11-03 |
| BR112017023232A2 (pt) | 2018-08-07 |
| AU2016255573A1 (en) | 2017-12-21 |
| IL289404A (en) | 2022-02-01 |
| MX2017013878A (es) | 2018-06-22 |
| CN107849604A (zh) | 2018-03-27 |
| US20180142296A1 (en) | 2018-05-24 |
| AU2022203482A1 (en) | 2022-06-09 |
| IL255301A0 (en) | 2017-12-31 |
| EA201792389A1 (ru) | 2018-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL289404A (en) | Optimal mismatch amplification from real-time multiplex-PCR for cell-free DNA estimation | |
| HK1248284A1 (zh) | 多重乳液核酸擴增 | |
| IL254516A0 (en) | cd137-specific proteins | |
| SG11201608585RA (en) | Modified transposases for improved insertion sequence bias and increased dna input tolerance | |
| HK1253372A1 (zh) | 作為bace1抑制劑的2-氨基-3-氟-3-(氟甲基)-6-甲基-6-苯基-3，4，5，6-四氫吡啶 | |
| GB2540441B (en) | Amplifiers | |
| SG11201610315YA (en) | Sample preparation for nucleic acid amplification | |
| IL262641A (en) | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing fetal well being | |
| EP3156789C0 (en) | BIOSENSOR | |
| EP3240910A4 (en) | Multiplex quantitative pcr | |
| IL252724A0 (en) | A modular architecture optimized for the preparation of microsatellites | |
| IL262640A (en) | Multiplexed optimal mismatch amplification (moma)-real-time pcr for cancer assessment | |
| IL255834A (en) | Electrochemical biosensor | |
| HK1251621A1 (zh) | 生物傳感器 | |
| EP3346006A4 (en) | DNA AMPLIFICATION METHOD | |
| HK1250682A1 (zh) | 核酸擴增 | |
| PT3350597T (pt) | Substrato para amplificação da fluorescência | |
| IL257500A (en) | Altered cullin1 gene | |
| GB201517241D0 (en) | DNA modification | |
| EP3134551A4 (en) | Compositions and methods for enhancing and/or predicting dna amplification | |
| HK1244036A1 (zh) | Pcr方法 | |
| EP3295959A4 (en) | Cmlck gene introduction | |
| EP3398778A4 (en) | BIOLOGICAL PRINTER | |
| GB201721053D0 (en) | DNA polymerases | |
| GB201522414D0 (en) | Monoamine oxidase B binders |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AM | Amended specification (according sect 146 of patent law) |
Free format text: CORRECTION OF THE NAME OF THE APPLICANT FROM MEDICAL COLLEGE OF WISCONSIN, INC. T Effective date: 20190925 |