HK1250737A1 - 结合cd79的抗体分子 - Google Patents
结合cd79的抗体分子 Download PDFInfo
- Publication number
- HK1250737A1 HK1250737A1 HK18110248.9A HK18110248A HK1250737A1 HK 1250737 A1 HK1250737 A1 HK 1250737A1 HK 18110248 A HK18110248 A HK 18110248A HK 1250737 A1 HK1250737 A1 HK 1250737A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- antibody molecules
- bind
- seq
- binding domain
- compositions
- Prior art date
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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- C07K2317/00—Immunoglobulins specific features
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- C07K2317/55—Fab or Fab'
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2015/066369 WO2016009030A2 (en) | 2014-07-16 | 2015-07-16 | Molecules with specificity for cd79 and cd22 |
| EPPCT/EP2015/066369 | 2015-07-16 | ||
| EPPCT/EP2015/066368 | 2015-07-16 | ||
| PCT/EP2015/066368 WO2016009029A1 (en) | 2014-07-16 | 2015-07-16 | Molecules with specificity for cd45 and cd79 |
| GB201601075 | 2016-01-20 | ||
| GBGB1601075.3A GB201601075D0 (en) | 2016-01-20 | 2016-01-20 | Antibodies molecules |
| PCT/EP2016/066989 WO2017009474A1 (en) | 2015-07-16 | 2016-07-15 | Antibody molecules which bind cd79 |
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| HK1250737A1 true HK1250737A1 (zh) | 2019-01-11 |
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| HK18110248.9A HK1250737A1 (zh) | 2015-07-16 | 2016-07-15 | 结合cd79的抗体分子 |
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| EP (1) | EP3322728A1 (zh) |
| JP (1) | JP6998857B2 (zh) |
| KR (1) | KR20180030662A (zh) |
| CN (1) | CN107922492B (zh) |
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| GB (1) | GB201601075D0 (zh) |
| HK (1) | HK1250737A1 (zh) |
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| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| GB201412658D0 (en) * | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201521382D0 (en) * | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521393D0 (en) * | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201807870D0 (en) | 2018-05-15 | 2018-06-27 | Autolus Ltd | A CD79-specific chimeric antigen receptor |
| EP3806857A4 (en) * | 2018-06-14 | 2022-03-02 | 2seventy bio, Inc. | CD79A CHIMERIC ANTIGEN RECEPTORS |
| AU2019287720B2 (en) | 2018-06-14 | 2025-08-28 | Regeneron Pharmaceuticals, Inc. | CD79A chimeric antigen receptors |
| JP2022513338A (ja) * | 2018-10-03 | 2022-02-07 | ネペンザ・バイオサイエンシズ・エルエルシー | 抗cd79抗体およびその使用 |
| KR20210121102A (ko) | 2019-01-28 | 2021-10-07 | 투오지에 바이오텍 (상하이) 컴퍼니 리미티드 | 항-cd79b 항체, 이의 항원-결합 단편, 및 이의 약학적 용도 |
| CN110684740B (zh) * | 2019-08-09 | 2020-12-08 | 无锡傲锐东源生物科技有限公司 | 一种抗人泛素羧基末端水解酶-1(uch-l1)的单克隆抗体及其应用 |
| TW202542200A (zh) * | 2022-12-29 | 2025-11-01 | 美商Ltz治療股份有限公司 | 抗CD79b抗體及其用途 |
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2016
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- 2016-07-15 BR BR112018000632A patent/BR112018000632A8/pt not_active IP Right Cessation
- 2016-07-15 HK HK18110248.9A patent/HK1250737A1/zh unknown
- 2016-07-15 EP EP16739476.6A patent/EP3322728A1/en active Pending
- 2016-07-15 CN CN201680041930.9A patent/CN107922492B/zh active Active
- 2016-07-15 EA EA201890320A patent/EA201890320A1/ru unknown
- 2016-07-15 AU AU2016293119A patent/AU2016293119A1/en not_active Abandoned
- 2016-07-15 KR KR1020187004606A patent/KR20180030662A/ko not_active Withdrawn
- 2016-07-15 US US15/743,764 patent/US10618957B2/en active Active
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- 2016-07-15 WO PCT/EP2016/066989 patent/WO2017009474A1/en not_active Ceased
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| CN107922492A (zh) | 2018-04-17 |
| CA2992371A1 (en) | 2017-01-19 |
| US10618957B2 (en) | 2020-04-14 |
| WO2017009474A1 (en) | 2017-01-19 |
| GB201601075D0 (en) | 2016-03-02 |
| EP3322728A1 (en) | 2018-05-23 |
| CL2018000107A1 (es) | 2018-07-27 |
| MX2018000590A (es) | 2018-08-01 |
| US20180201678A1 (en) | 2018-07-19 |
| JP6998857B2 (ja) | 2022-02-10 |
| BR112018000632A8 (pt) | 2023-03-21 |
| EA201890320A1 (ru) | 2018-06-29 |
| CO2018000410A2 (es) | 2018-04-10 |
| IL256853A (en) | 2018-03-29 |
| AU2016293119A1 (en) | 2018-01-25 |
| KR20180030662A (ko) | 2018-03-23 |
| BR112018000632A2 (pt) | 2018-09-18 |
| CN107922492B (zh) | 2022-03-18 |
| JP2018529313A (ja) | 2018-10-11 |
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