HK1250737A1 - 结合cd79的抗体分子 - Google Patents
结合cd79的抗体分子 Download PDFInfo
- Publication number
- HK1250737A1 HK1250737A1 HK18110248.9A HK18110248A HK1250737A1 HK 1250737 A1 HK1250737 A1 HK 1250737A1 HK 18110248 A HK18110248 A HK 18110248A HK 1250737 A1 HK1250737 A1 HK 1250737A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- antibody molecules
- bind
- seq
- binding domain
- compositions
- Prior art date
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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- C07K2317/00—Immunoglobulins specific features
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| EPPCT/EP2015/066368 | 2015-07-16 | ||
| PCT/EP2015/066368 WO2016009029A1 (en) | 2014-07-16 | 2015-07-16 | Molecules with specificity for cd45 and cd79 |
| EPPCT/EP2015/066369 | 2015-07-16 | ||
| PCT/EP2015/066369 WO2016009030A2 (en) | 2014-07-16 | 2015-07-16 | Molecules with specificity for cd79 and cd22 |
| GB201601075 | 2016-01-20 | ||
| GBGB1601075.3A GB201601075D0 (en) | 2016-01-20 | 2016-01-20 | Antibodies molecules |
| PCT/EP2016/066989 WO2017009474A1 (en) | 2015-07-16 | 2016-07-15 | Antibody molecules which bind cd79 |
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| HK1250737A1 true HK1250737A1 (zh) | 2019-01-11 |
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| HK18110248.9A HK1250737A1 (zh) | 2015-07-16 | 2016-07-15 | 结合cd79的抗体分子 |
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| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521393D0 (en) * | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521382D0 (en) * | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201807870D0 (en) | 2018-05-15 | 2018-06-27 | Autolus Ltd | A CD79-specific chimeric antigen receptor |
| US20220226374A1 (en) * | 2018-06-14 | 2022-07-21 | 2seventy bio, Inc | Cd79b chimeric antigen receptors |
| EP3806903B1 (en) * | 2018-06-14 | 2024-02-14 | 2seventy bio, Inc. | Cd79a chimeric antigen receptors |
| CN120022359A (zh) * | 2018-10-03 | 2025-05-23 | 柰裴斯生命科学公司 | 抗cd79抗体及其应用 |
| WO2020156439A1 (zh) | 2019-01-28 | 2020-08-06 | 上海拓界生物医药科技有限公司 | 抗cd79b抗体、其抗原结合片段及其医药用途 |
| CN110684740B (zh) * | 2019-08-09 | 2020-12-08 | 无锡傲锐东源生物科技有限公司 | 一种抗人泛素羧基末端水解酶-1(uch-l1)的单克隆抗体及其应用 |
| TWI894742B (zh) * | 2022-12-29 | 2025-08-21 | 美商Ltz治療股份有限公司 | 抗CD79b抗體及其用途 |
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| BR112014029888A2 (pt) | 2012-06-27 | 2020-05-12 | Hoffmann La Roche | Métodos de produção de um anticorpo, de determinação de uma combinação de sítios de ligação e de tratamento de um indivíduo com câncer, formulação farmacêutica, anticorpo e uso de um anticorpo |
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| JP2015523380A (ja) | 2012-07-09 | 2015-08-13 | ジェネンテック, インコーポレイテッド | 抗cd79b抗体を含む免疫複合体 |
| HK1207972A1 (zh) * | 2012-07-09 | 2016-02-19 | 基因泰克公司 | 包含抗cd79b抗體的免疫偶聯物 |
| TW201408696A (zh) | 2012-07-09 | 2014-03-01 | Genentech Inc | 抗cd22抗體及免疫結合物 |
| RU2015105588A (ru) | 2012-07-19 | 2016-09-10 | Редвуд Байосайнс, Инк. | Антитело, специфическое к cd22, и способы его применения |
| US9682143B2 (en) | 2012-08-14 | 2017-06-20 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| KR101963231B1 (ko) | 2012-09-11 | 2019-03-28 | 삼성전자주식회사 | 이중특이 항체의 제작을 위한 단백질 복합체 및 이를 이용한 이중특이 항체 제조 방법 |
| GB201223276D0 (en) | 2012-12-21 | 2013-02-06 | Ucb Pharma Sa | Antibodies and methods of producing same |
| CN105143270B (zh) | 2013-02-26 | 2019-11-12 | 罗切格利卡特公司 | 双特异性t细胞活化抗原结合分子 |
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| UA116479C2 (uk) | 2013-08-09 | 2018-03-26 | Макродженікс, Інк. | БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ |
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| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| GB201411320D0 (en) | 2014-06-25 | 2014-08-06 | Ucb Biopharma Sprl | Antibody construct |
| GB201411420D0 (en) | 2014-06-26 | 2014-08-13 | Ucb Biopharma Sprl | Antibody constructs |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| CA2957313C (en) | 2014-08-06 | 2023-05-09 | Astellas Pharma Inc. | Novel anti-human ig.beta. antibody |
| JP6802158B2 (ja) | 2014-12-05 | 2020-12-16 | ジェネンテック, インコーポレイテッド | 抗CD79b抗体及び使用方法 |
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| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521393D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| WO2018112407A1 (en) | 2016-12-15 | 2018-06-21 | Duke University | Antibodies and methods for depleting regulatory b10 cells and use in combination with immune checkpoint inhibitors |
-
2016
- 2016-01-20 GB GBGB1601075.3A patent/GB201601075D0/en not_active Ceased
- 2016-07-15 JP JP2018501993A patent/JP6998857B2/ja active Active
- 2016-07-15 KR KR1020187004606A patent/KR20180030662A/ko not_active Withdrawn
- 2016-07-15 HK HK18110248.9A patent/HK1250737A1/zh unknown
- 2016-07-15 EP EP16739476.6A patent/EP3322728A1/en active Pending
- 2016-07-15 MX MX2018000590A patent/MX2018000590A/es unknown
- 2016-07-15 BR BR112018000632A patent/BR112018000632A8/pt not_active IP Right Cessation
- 2016-07-15 US US15/743,764 patent/US10618957B2/en active Active
- 2016-07-15 CA CA2992371A patent/CA2992371A1/en active Pending
- 2016-07-15 EA EA201890320A patent/EA201890320A1/ru unknown
- 2016-07-15 AU AU2016293119A patent/AU2016293119A1/en not_active Abandoned
- 2016-07-15 WO PCT/EP2016/066989 patent/WO2017009474A1/en not_active Ceased
- 2016-07-15 CN CN201680041930.9A patent/CN107922492B/zh active Active
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2018
- 2018-01-11 IL IL256853A patent/IL256853A/en unknown
- 2018-01-12 CL CL2018000107A patent/CL2018000107A1/es unknown
- 2018-01-17 CO CONC2018/0000410A patent/CO2018000410A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018529313A (ja) | 2018-10-11 |
| AU2016293119A1 (en) | 2018-01-25 |
| EA201890320A1 (ru) | 2018-06-29 |
| WO2017009474A1 (en) | 2017-01-19 |
| IL256853A (en) | 2018-03-29 |
| BR112018000632A2 (pt) | 2018-09-18 |
| US10618957B2 (en) | 2020-04-14 |
| US20180201678A1 (en) | 2018-07-19 |
| GB201601075D0 (en) | 2016-03-02 |
| MX2018000590A (es) | 2018-08-01 |
| BR112018000632A8 (pt) | 2023-03-21 |
| CN107922492B (zh) | 2022-03-18 |
| CO2018000410A2 (es) | 2018-04-10 |
| CL2018000107A1 (es) | 2018-07-27 |
| EP3322728A1 (en) | 2018-05-23 |
| KR20180030662A (ko) | 2018-03-23 |
| JP6998857B2 (ja) | 2022-02-10 |
| CN107922492A (zh) | 2018-04-17 |
| CA2992371A1 (en) | 2017-01-19 |
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