HK1248739A1 - 聚合物骨架元素標簽 - Google Patents
聚合物骨架元素標簽Info
- Publication number
- HK1248739A1 HK1248739A1 HK18108653.1A HK18108653A HK1248739A1 HK 1248739 A1 HK1248739 A1 HK 1248739A1 HK 18108653 A HK18108653 A HK 18108653A HK 1248739 A1 HK1248739 A1 HK 1248739A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- polymer backbone
- element tags
- backbone element
- tags
- polymer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
- C08F220/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
- C08F220/56—Acrylamide; Methacrylamide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/14—Esterification
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
- C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/42—Introducing metal atoms or metal-containing groups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80335606P | 2006-05-27 | 2006-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1248739A1 true HK1248739A1 (zh) | 2018-10-19 |
Family
ID=38778063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18108653.1A HK1248739A1 (zh) | 2006-05-27 | 2018-07-04 | 聚合物骨架元素標簽 |
Country Status (9)
Country | Link |
---|---|
US (6) | US9012239B2 (zh) |
EP (4) | EP2960263B1 (zh) |
CN (2) | CN107573445B (zh) |
CA (1) | CA2653408C (zh) |
DK (1) | DK2444804T3 (zh) |
ES (1) | ES2553141T3 (zh) |
HK (1) | HK1248739A1 (zh) |
PT (1) | PT2444804E (zh) |
WO (1) | WO2007137418A1 (zh) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
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US7479630B2 (en) * | 2004-03-25 | 2009-01-20 | Bandura Dmitry R | Method and apparatus for flow cytometry linked with elemental analysis |
US7591994B2 (en) * | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
CA2506388A1 (en) * | 2004-05-05 | 2005-11-05 | Tieneke Emily Dykstra | Surface modification of nanocrystals using multidentate polymer ligands |
CA2640508C (en) | 2006-02-13 | 2014-04-15 | Olga Ornatsky | Gene expression assays conducted by elemental analysis |
US8101368B2 (en) * | 2006-02-13 | 2012-01-24 | Dvs Sciences Inc. | Quantitation of cellular DNA and cell numbers using element labeling |
US9012239B2 (en) | 2006-05-27 | 2015-04-21 | Fluidigm Canada Inc. | Polymer backbone element tags |
EP2037272B1 (en) * | 2006-06-30 | 2013-09-18 | JNC Corporation | Kit for detection/quantification of analyte, and method for detection/quantification of analyte |
CA2658787C (en) | 2006-08-15 | 2013-04-09 | Alexei Antonov | Apparatus and method for elemental analysis of particles by mass spectrometry |
US7875747B2 (en) * | 2006-10-10 | 2011-01-25 | Afton Chemical Corporation | Branched succinimide dispersant compounds and methods of making the compounds |
EP2092294B1 (en) | 2006-11-02 | 2015-06-03 | Mitchell A. Winnik | Particles containing detectable elemental code |
CA2687178C (en) * | 2007-05-23 | 2014-02-04 | Ventana Medical Systems, Inc. | Polymeric carriers for immunohistochemistry and in situ hybridization |
DE102007049335A1 (de) * | 2007-10-12 | 2009-04-16 | Qiagen Gmbh | Wasserlösliche Polymere mit Chelatoren |
AU2011237729B2 (en) | 2010-04-05 | 2014-04-03 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
DE102012104504B4 (de) | 2012-05-24 | 2021-10-07 | Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Wirtschaft und Technologie, dieses vertreten durch den Präsidenten der BAM, Bundesanstalt für Materialforschung und -prüfung | Polypeptidmarker |
EP3901280A1 (en) | 2012-10-17 | 2021-10-27 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
WO2014079802A2 (en) | 2012-11-20 | 2014-05-30 | Ventana Medical Systems, Inc. | Laser ablation inductively-coupled plasma mass spectral tissue diagnostics |
CN105378469A (zh) * | 2013-05-28 | 2016-03-02 | 富鲁达加拿大公司 | 分子血细胞计数 |
US9218949B2 (en) | 2013-06-04 | 2015-12-22 | Fluidigm Canada, Inc. | Strategic dynamic range control for time-of-flight mass spectrometry |
EP4234716A3 (en) | 2013-06-25 | 2023-12-06 | Prognosys Biosciences, Inc. | Methods for determining spatial patterns of biological targets in a sample |
US10041949B2 (en) | 2013-09-13 | 2018-08-07 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed imaging of tissues using mass tags and secondary ion mass spectrometry |
CN107406410B (zh) | 2014-08-20 | 2021-10-29 | 多伦多大学理事会 | 有机碲化合物、组合物及其使用方法 |
EP3191840B1 (en) * | 2014-09-12 | 2020-04-08 | Purdue Research Foundation | Metal-antibody tagging and plasma-based detection |
US20160139141A1 (en) * | 2014-11-13 | 2016-05-19 | Fluidigm Canada Inc. | Imaging mass cytometry using molecular tagging |
JP6757730B2 (ja) | 2014-12-31 | 2020-09-23 | フリューダイム カナダ インコーポレイテッド | マスサイトメトリーによる分析用の構造化生体試料 |
WO2016153819A1 (en) | 2015-03-25 | 2016-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis using secondary ion mass spectrometry |
CA2982146A1 (en) | 2015-04-10 | 2016-10-13 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
US10935545B2 (en) | 2015-05-13 | 2021-03-02 | Slsbio Co., Ltd. | Simultaneous analysis method for multiple targets using multiple metal nano-tags |
US11738321B2 (en) * | 2016-06-02 | 2023-08-29 | The Regents Of The University Of California | Lanthanide-chelator combinatorial barcoding |
CN107255722A (zh) * | 2017-04-26 | 2017-10-17 | 马鞍山易廷生物科技有限公司 | 基于金属同位素标记流式结合icp‑ms的单细胞蛋白检测方法 |
WO2019089088A1 (en) | 2017-11-03 | 2019-05-09 | Fluidigm Canada Inc. | Reagents and methods for elemental imaging mass spectrometry of biological samples |
CN112262316A (zh) * | 2018-04-13 | 2021-01-22 | 富鲁达加拿大公司 | 用于元素分析的稳定细胞采集 |
WO2019209657A1 (en) * | 2018-04-23 | 2019-10-31 | The Board Of Trustees Of The Leland Stanford Junior University | Labeling of molecular probes with nonmetal and metalloid isotopes for multiplexed high resolution analysis |
CA3101613A1 (en) * | 2018-05-31 | 2019-12-05 | George Mason Research Foundation, Inc. | Organometallic labels for the detection of biomolecules, methods of synthesis and processes for conjugating an organometallic labels to a biomolecule |
CN111693691B (zh) * | 2019-03-14 | 2023-09-05 | 天津华科泰生物技术有限公司 | 一种基于卟啉结构的聚合物标签 |
CN114127974B (zh) * | 2019-05-13 | 2023-04-18 | 上海宸安生物科技有限公司 | 用于标记生物分子的标志 |
CN115135680A (zh) * | 2019-12-18 | 2022-09-30 | 标准生物工具加拿大公司 | 用于信号放大的质谱细胞术试剂和方法 |
CA3177923A1 (en) * | 2020-05-18 | 2021-11-25 | Shanghai Polaris Biology Co., Ltd. | Microbeads and uses thereof |
EP4215025A1 (en) | 2020-09-18 | 2023-07-26 | Fluidigm Canada Inc. | Inductively coupled plasma based atomic analysis systems and methods |
CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
CN113588523B (zh) * | 2021-07-26 | 2022-03-29 | 浙江大学 | 一种用于质谱流式细胞技术的基于框架结构的纳米颗粒及其制备方法 |
CN114062565B (zh) * | 2022-01-14 | 2022-03-29 | 北京先通国际医药科技股份有限公司 | 一种检测样品中含dota环或nota环的化合物的方法 |
CN115322289B (zh) * | 2022-02-22 | 2024-03-26 | 中国科学院苏州生物医学工程技术研究所 | 用于质谱流式细胞术的稀土金属配位的聚集诱导发光聚合物 |
WO2023176963A1 (ja) * | 2022-03-17 | 2023-09-21 | 株式会社島津製作所 | 小胞に存在する生体分子の分析方法 |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
SE454781B (sv) | 1986-10-17 | 1988-05-30 | Wallac Oy | Hybridiseringsforfarande for detektion av polynukleotidsekvens |
US4962045A (en) | 1988-05-02 | 1990-10-09 | The Perkin-Elmer Corporation | Time-resolved fluorimetric detection of lanthanide labeled nucleotides |
US5914095A (en) * | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
US5554748A (en) * | 1989-04-07 | 1996-09-10 | Nycomed Salutar, Inc. | Adducts of macrocyclic chelants |
US6031074A (en) * | 1989-08-25 | 2000-02-29 | National Institutes Of Health | Automated Peptide design and synthesis |
DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
AU670108B2 (en) * | 1992-09-11 | 1996-07-04 | Becton Dickinson & Company | Improved antibodies to plasmodium falciparum |
US6203775B1 (en) * | 1993-03-19 | 2001-03-20 | The General Hospital Corporation | Chelating polymers for labeling of proteins |
US6060040A (en) * | 1996-12-23 | 2000-05-09 | Bracco Research S.A. | Cross-linked polymeric compositions for increasing the MRI contrast in visualising the digestive tract of patients |
US20040248801A1 (en) * | 2000-03-21 | 2004-12-09 | Kiessling Laura L. | Methods and reagents for regulation of cellular responses in biological systems |
US6806289B1 (en) * | 2000-07-14 | 2004-10-19 | Stephen J. Lippard | Coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same |
JP2004511223A (ja) * | 2000-08-08 | 2004-04-15 | アクララ バイオサイエンシーズ, インコーポレイテッド | 多重化酵素アッセイ |
GB0030727D0 (en) * | 2000-12-15 | 2001-01-31 | Lumitech Uk Ltd | Methods and kits for detecting kinase activity |
US7700295B2 (en) | 2000-12-28 | 2010-04-20 | Mds Sciex | Elemental analysis of tagged biologically active materials |
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CA2431864C (en) | 2000-12-28 | 2011-09-06 | Mds Inc., Doing Business As Mds Sciex | Elemental analysis of tagged biologically active materials |
US7479630B2 (en) | 2004-03-25 | 2009-01-20 | Bandura Dmitry R | Method and apparatus for flow cytometry linked with elemental analysis |
US20040043030A1 (en) * | 2001-07-31 | 2004-03-04 | Immunomedics, Inc. | Polymeric delivery systems |
US20040171034A1 (en) * | 2002-05-03 | 2004-09-02 | Brian Agnew | Compositions and methods for detection and isolation of phosphorylated molecules |
US20040146961A1 (en) | 2002-12-20 | 2004-07-29 | Brian Noland | Fret-based homogeneous in vitro phosphate transfer assay system |
US20040258614A1 (en) * | 2003-06-20 | 2004-12-23 | University Of Maryland, Baltimore | Microparticles for microarterial imaging and radiotherapy |
JP4736310B2 (ja) * | 2003-07-14 | 2011-07-27 | 富士ゼロックス株式会社 | マレイミド基含有ポリマー粒子およびその製造方法 |
JP2007516973A (ja) * | 2003-12-12 | 2007-06-28 | キューティーエル バイオシステムズ リミティド ライアビリティ カンパニー | 金属イオン介在性蛍光スーパークエンチングアッセイ、キット及び試薬 |
US20050218139A1 (en) | 2004-03-31 | 2005-10-06 | Hp Intellectual Corporation | Intelligent user interface for new cooking technologies |
SE0400916D0 (sv) * | 2004-04-05 | 2004-04-05 | Amersham Biosciences Ab | Polymeric ligands |
WO2005123959A2 (en) | 2004-06-10 | 2005-12-29 | Perkinelmer Las, Inc. | Multiplexing assays for analyte detection |
CA2572226A1 (en) * | 2004-06-28 | 2006-02-02 | Bruce R. Line | Radiolabeled nanohybrids targeting solid tumor neovasculature and method of using same |
CN1321122C (zh) * | 2005-02-03 | 2007-06-13 | 华东师范大学 | 一种水热合成钆-二乙三胺五乙酸的方法 |
CA2642201C (en) | 2006-02-13 | 2014-09-02 | Olga Ornatsky | Kinase and phosphatase assays conducted by elemental analysis |
US9012239B2 (en) | 2006-05-27 | 2015-04-21 | Fluidigm Canada Inc. | Polymer backbone element tags |
-
2007
- 2007-05-28 US US11/754,340 patent/US9012239B2/en active Active
- 2007-05-28 EP EP15177058.3A patent/EP2960263B1/en active Active
- 2007-05-28 CN CN201710702403.4A patent/CN107573445B/zh active Active
- 2007-05-28 CA CA2653408A patent/CA2653408C/en active Active
- 2007-05-28 WO PCT/CA2007/000946 patent/WO2007137418A1/en active Application Filing
- 2007-05-28 EP EP17176041.6A patent/EP3260863B1/en active Active
- 2007-05-28 CN CN200780027791.5A patent/CN101495867B/zh active Active
- 2007-05-28 PT PT110080355T patent/PT2444804E/pt unknown
- 2007-05-28 EP EP07719866.1A patent/EP2021793B1/en active Active
- 2007-05-28 ES ES11008035.5T patent/ES2553141T3/es active Active
- 2007-05-28 DK DK11008035.5T patent/DK2444804T3/en active
- 2007-05-28 EP EP11008035.5A patent/EP2444804B1/en active Active
-
2015
- 2015-03-16 US US14/659,224 patent/US9296838B2/en active Active
- 2015-10-05 US US14/875,553 patent/US10072104B2/en active Active
-
2018
- 2018-07-04 HK HK18108653.1A patent/HK1248739A1/zh unknown
- 2018-07-27 US US16/047,927 patent/US10669358B2/en active Active
-
2019
- 2019-07-09 US US16/506,243 patent/US10752707B2/en active Active
-
2020
- 2020-05-05 US US16/867,023 patent/US20200362062A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20190077890A1 (en) | 2019-03-14 |
EP2021793B1 (en) | 2017-04-26 |
PT2444804E (pt) | 2015-11-25 |
EP2444804A3 (en) | 2014-04-30 |
US20190345272A1 (en) | 2019-11-14 |
EP2444804A2 (en) | 2012-04-25 |
CN107573445A (zh) | 2018-01-12 |
WO2007137418A1 (en) | 2007-12-06 |
US10072104B2 (en) | 2018-09-11 |
US20150183895A1 (en) | 2015-07-02 |
US20080003616A1 (en) | 2008-01-03 |
EP2021793A4 (en) | 2009-07-29 |
US20200362062A1 (en) | 2020-11-19 |
US10669358B2 (en) | 2020-06-02 |
CA2653408C (en) | 2017-08-01 |
CN101495867A (zh) | 2009-07-29 |
CN107573445B (zh) | 2021-05-25 |
DK2444804T3 (en) | 2015-11-30 |
EP3260863A1 (en) | 2017-12-27 |
EP2960263A1 (en) | 2015-12-30 |
CN101495867B (zh) | 2017-09-05 |
CA2653408A1 (en) | 2007-12-06 |
EP2021793A1 (en) | 2009-02-11 |
ES2553141T3 (es) | 2015-12-04 |
US9296838B2 (en) | 2016-03-29 |
US9012239B2 (en) | 2015-04-21 |
US10752707B2 (en) | 2020-08-25 |
US20160025731A1 (en) | 2016-01-28 |
EP3260863B1 (en) | 2021-03-10 |
EP2960263B1 (en) | 2017-07-12 |
EP2444804B1 (en) | 2015-10-07 |
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