HK1248221A1 - 異噻唑啉酮類，吡唑並嘧啶酮類和吡咯並嘧啶酮作為泛蛋白特異性蛋白酶7抑制劑 - Google Patents

異噻唑啉酮類，吡唑並嘧啶酮類和吡咯並嘧啶酮作為泛蛋白特異性蛋白酶7抑制劑

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Publication number
HK1248221A1
HK1248221A1 HK18107586.5A HK18107586A HK1248221A1 HK 1248221 A1 HK1248221 A1 HK 1248221A1 HK 18107586 A HK18107586 A HK 18107586A HK 1248221 A1 HK1248221 A1 HK 1248221A1
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HK
Hong Kong
Prior art keywords
pyrrolopyrimidinones
isothiazolopyrimidinones
pyrazolopyrimidinones
ubiquitin
inhibitors
Prior art date
Application number
HK18107586.5A
Other languages
English (en)
Inventor
Stephanos Ioannidis
Adam Charles Talbot
Bruce Follows
Alexandre Joseph Buckmelter
Minghua Wang
Ann-Marie Campbell
Original Assignee
Forma Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forma Therapeutics Inc filed Critical Forma Therapeutics Inc
Publication of HK1248221A1 publication Critical patent/HK1248221A1/zh

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    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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HK18107586.5A 2015-02-05 2018-06-11 異噻唑啉酮類，吡唑並嘧啶酮類和吡咯並嘧啶酮作為泛蛋白特異性蛋白酶7抑制劑 HK1248221A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562112540P 2015-02-05 2015-02-05
PCT/US2016/016556 WO2016126935A1 (en) 2015-02-05 2016-02-04 Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors

Publications (1)

Publication Number Publication Date
HK1248221A1 true HK1248221A1 (zh) 2018-10-12

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HK18107586.5A HK1248221A1 (zh) 2015-02-05 2018-06-11 異噻唑啉酮類，吡唑並嘧啶酮類和吡咯並嘧啶酮作為泛蛋白特異性蛋白酶7抑制劑

Country Status (5)

Country Link
US (4) US9938300B2 (zh)
EP (1) EP3253759A1 (zh)
JP (1) JP2018504432A (zh)
HK (1) HK1248221A1 (zh)
WO (1) WO2016126935A1 (zh)

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CN113087724B (zh) * 2020-01-08 2024-01-19 四川科伦博泰生物医药股份有限公司 异噻唑并嘧啶酮类化合物，包含其的药物组合物及其用途
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